Details for: ARHGEF3

Gene ID: 50650

Symbol: ARHGEF3

Ensembl ID: ENSG00000163947

Description: Rho guanine nucleotide exchange factor 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 256.3885
    Cell Significance Index: -39.8800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 152.4581
    Cell Significance Index: -38.6700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 97.1726
    Cell Significance Index: -40.0300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 87.6785
    Cell Significance Index: -35.6200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 77.4128
    Cell Significance Index: -39.8200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.4342
    Cell Significance Index: -35.7400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 32.4586
    Cell Significance Index: -40.0200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.1931
    Cell Significance Index: -35.4400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.5794
    Cell Significance Index: -44.7800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.0163
    Cell Significance Index: -32.1900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.1747
    Cell Significance Index: -40.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 5.2067
    Cell Significance Index: 145.5100
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 4.1258
    Cell Significance Index: 25.4600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.7616
    Cell Significance Index: 143.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.5329
    Cell Significance Index: 72.2800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.4945
    Cell Significance Index: 30.9400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4832
    Cell Significance Index: 498.1200
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.0588
    Cell Significance Index: 18.2800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.6464
    Cell Significance Index: 23.6800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.5779
    Cell Significance Index: 106.1000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.4638
    Cell Significance Index: 28.5700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.4215
    Cell Significance Index: 509.8800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4018
    Cell Significance Index: 278.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.1173
    Cell Significance Index: 2060.5800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.0948
    Cell Significance Index: 29.3400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9502
    Cell Significance Index: 72.9200
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.7859
    Cell Significance Index: 8.1400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.7805
    Cell Significance Index: 1469.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7053
    Cell Significance Index: 69.7700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6824
    Cell Significance Index: 25.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6724
    Cell Significance Index: 607.1200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.6509
    Cell Significance Index: 1002.0100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.6405
    Cell Significance Index: 74.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.6048
    Cell Significance Index: 26.7500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.5199
    Cell Significance Index: 330.1800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.4995
    Cell Significance Index: 8.5600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4584
    Cell Significance Index: 317.0500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4495
    Cell Significance Index: 81.0300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3949
    Cell Significance Index: 48.5600
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: 0.3727
    Cell Significance Index: 3.7300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3661
    Cell Significance Index: 22.5000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3352
    Cell Significance Index: 54.5300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2956
    Cell Significance Index: 7.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2658
    Cell Significance Index: 145.1500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1884
    Cell Significance Index: 9.5200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1803
    Cell Significance Index: 245.1200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.1619
    Cell Significance Index: 2.1600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1425
    Cell Significance Index: 27.1100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1316
    Cell Significance Index: 14.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0900
    Cell Significance Index: 4.7300
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.0716
    Cell Significance Index: 1.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0668
    Cell Significance Index: 30.3400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0262
    Cell Significance Index: 4.4800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0211
    Cell Significance Index: 9.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0004
    Cell Significance Index: 0.0100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0102
    Cell Significance Index: -1.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0158
    Cell Significance Index: -9.8500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0242
    Cell Significance Index: -17.9100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0262
    Cell Significance Index: -0.9200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0323
    Cell Significance Index: -0.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0361
    Cell Significance Index: -20.3500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0416
    Cell Significance Index: -30.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0493
    Cell Significance Index: -37.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0502
    Cell Significance Index: -2.3400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0627
    Cell Significance Index: -2.8400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0710
    Cell Significance Index: -9.7500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0991
    Cell Significance Index: -6.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1074
    Cell Significance Index: -22.6200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1206
    Cell Significance Index: -34.6900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1523
    Cell Significance Index: -15.5500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1666
    Cell Significance Index: -3.6100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1705
    Cell Significance Index: -4.0900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1836
    Cell Significance Index: -8.6300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1850
    Cell Significance Index: -10.3800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2383
    Cell Significance Index: -27.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2461
    Cell Significance Index: -31.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2502
    Cell Significance Index: -28.6600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2550
    Cell Significance Index: -16.4500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2642
    Cell Significance Index: -15.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2692
    Cell Significance Index: -28.0400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2741
    Cell Significance Index: -3.7400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2744
    Cell Significance Index: -32.3700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3597
    Cell Significance Index: -26.8100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3598
    Cell Significance Index: -46.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3617
    Cell Significance Index: -18.7900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4176
    Cell Significance Index: -12.2700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4329
    Cell Significance Index: -6.2000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4701
    Cell Significance Index: -37.2300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.4847
    Cell Significance Index: -6.9000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5014
    Cell Significance Index: -35.4600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5268
    Cell Significance Index: -11.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5345
    Cell Significance Index: -10.7300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5480
    Cell Significance Index: -33.6000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5485
    Cell Significance Index: -17.4700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.5874
    Cell Significance Index: -6.4000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6031
    Cell Significance Index: -12.5100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.6223
    Cell Significance Index: -3.7600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6316
    Cell Significance Index: -20.6800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6488
    Cell Significance Index: -14.9900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6719
    Cell Significance Index: -9.9200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Rho GTPase-Activating Protein (RhoGAP) Activity:** ARHGEF3 possesses RhoGAP activity, which regulates the activity of Rho GTPases by accelerating their GTP hydrolysis. This activity is essential for controlling the Rho GTPase cycle and modulating downstream signaling pathways. 2. **Cell Signaling Modulation:** ARHGEF3 regulates various signaling pathways, including cell death signaling, GPCR downstream signaling, and small GTPase-mediated signal transduction. Its dysregulation can lead to aberrant signaling and contribute to disease development. 3. **Expression in Different Cell Types:** ARHGEF3 is expressed in diverse cell types, including hematopoietic cells, epithelial cells, immune cells, and stem cells, underscoring its importance in maintaining tissue homeostasis and immune function. 4. **Protein-Protein Interactions:** ARHGEF3 interacts with various proteins, including NRAGE, NRI, and P75 NTR, which are involved in cell death signaling and immune responses. **Pathways and Functions:** 1. **Cell Death Signaling:** ARHGEF3 modulates cell death signaling pathways, including those involving NRAGE, NRI, and P75 NTR. Its dysregulation can lead to aberrant cell death and contribute to disease development. 2. **GPCR Downstream Signaling:** ARHGEF3 regulates GPCR downstream signaling, which is essential for controlling various cellular processes, including cell growth, differentiation, and survival. 3. **Small GTPase-Mediated Signal Transduction:** ARHGEF3 regulates small GTPase-mediated signal transduction, which is critical for controlling cytoskeleton organization, cell migration, and cell death signaling. 4. **Rho GTPase Cycle Regulation:** ARHGEF3 regulates the Rho GTPase cycle, which is essential for controlling cell growth, differentiation, and survival. **Clinical Significance:** 1. **Cancer:** ARHGEF3 dysregulation has been implicated in various cancers, including leukemia, lymphoma, and solid tumors. Its dysregulation can contribute to aberrant cell growth, differentiation, and survival. 2. **Immunological Disorders:** ARHGEF3 dysregulation has been linked to immunological disorders, including autoimmune diseases and immunodeficiency syndromes. Its dysregulation can contribute to aberrant immune responses and tissue damage. 3. **Neurological Disorders:** ARHGEF3 dysregulation has been implicated in various neurological disorders, including Parkinson's disease, Alzheimer's disease, and multiple sclerosis. Its dysregulation can contribute to aberrant neural signaling and tissue damage. 4. **Infectious Diseases:** ARHGEF3 dysregulation has been linked to infectious diseases, including viral infections and bacterial infections. Its dysregulation can contribute to aberrant immune responses and tissue damage. In conclusion, ARHGEF3 is a critical gene involved in regulating various signaling pathways that control cell growth, differentiation, and survival. Its dysregulation has been implicated in various diseases, including cancer, immunological disorders, neurological disorders, and infectious diseases. Further research is needed to fully elucidate the role of ARHGEF3 in human health and disease.

Genular Protein ID: 2779413917

Symbol: ARHG3_HUMAN

Name: Rho guanine nucleotide exchange factor 3

UniProtKB Accession Codes:

Q9NR81 A8K5U7 Q4FZB6 Q4QQI5 Q4QQQ0 Q59F00 Q6NUN3 Q7Z4U2 Q7Z5T2 Q9H7T4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 3 ExpressionAtlas 1 GO 5 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 4 RefSeq 6 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10873612

Title: Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22.

PubMed ID: 10873612

DOI: 10.1006/bbrc.2000.2925

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12221096

Title: XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.

PubMed ID: 12221096

DOI: 10.1074/jbc.m207401200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

  • Length: 526
  • Mass: 59783
  • Checksum: 0FE8248AB52D1CBC
  • Sequence:
    • MVAKDYPFYL TVKRANCSLE LPPASGPAKD AEEPSNKRVK PLSRVTSLAN LIPPVKATPL 
KRFSQTLQRS ISFRSESRPD ILAPRPWSRN AAPSSTKRRD SKLWSETFDV CVNQMLTSKE 
IKRQEAIFEL SQGEEDLIED LKLAKKAYHD PMLKLSIMTE QELNQIFGTL DSLIPLHEEL 
LSQLRDVRKP DGSTEHVGPI LVGWLPCLSS YDSYCSNQVA AKALLDHKKQ DHRVQDFLQR 
CLESPFSRKL DLWNFLDIPR SRLVKYPLLL REILRHTPND NPDQQHLEEA INIIQGIVAE 
INTKTGESEC RYYKERLLYL EEGQKDSLID SSRVLCCHGE LKNNRGVKLH VFLFQEVLVI 
TRAVTHNEQL CYQLYRQPIP VKDLLLEDLQ DGEVRLGGSL RGAFSNNERI KNFFRVSFKN 
GSQSQTHSLQ ANDTFNKQQW LNCIRQAKET VLCAAGQAGV LDSEGSFLNP TTGSRELQGE 
TKLEQMDQSD SESDCSMDTS EVSLDCERME QTDSSCGNSR HGESNV

Genular Protein ID: 3592170991

Symbol: E9PG37_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PG37

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 532
  • Mass: 60790
  • Checksum: A8A32FEA5303B6D7
  • Sequence:
    • MRSERPMVWC CLFVRSQRKR KQSTQDEDAV SLCSLDISEP SNKRVKPLSR VTSLANLIPP 
VKATPLKRFS QTLQRSISFR SESRPDILAP RPWSRNAAPS STKRRDSKLW SETFDVCVNQ 
MLTSKEIKRQ EAIFELSQGE EDLIEDLKLA KKAYHDPMLK LSIMTEQELN QIFGTLDSLI 
PLHEELLSQL RDVRKPDGST EHVGPILVGW LPCLSSYDSY CSNQVAAKAL LDHKKQDHRV 
QDFLQRCLES PFSRKLDLWN FLDIPRSRLV KYPLLLREIL RHTPNDNPDQ QHLEEAINII 
QGIVAEINTK TGESECRYYK ERLLYLEEGQ KDSLIDSSRV LCCHGELKNN RGVKLHVFLF 
QEVLVITRAV THNEQLCYQL YRQPIPVKDL LLEDLQDGEV RLGGSLRGAF SNNERIKNFF 
RVSFKNGSQS QTHSLQANDT FNKQQWLNCI RQAKETVLCA AGQAGVLDSE GSFLNPTTGS 
RELQGETKLE QMDQSDSESD CSMDTSEVSL DCERMEQTDS SCGNSRHGES NV

Genular Protein ID: 1420657643

Symbol: B7Z6B2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z6B2

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 532
  • Mass: 60776
  • Checksum: 3F4A211154E3A338
  • Sequence:
    • MRSERPMVWC CLFVRSQRKR KQSTQDEDAV SLCSLDISEP SNKRVKPLSR VTSLANLIPP 
VKATPLKRFS QTLQRSISFR SESRPDILAP RPWSRNAAPS STKRRDSKLW SETFDVCVNQ 
MLTSKEIKRQ EAIFELSQGE EDLIEDLKLA KKAYHDPMLK LSIMTEQELN QIFGTLDSLI 
PLHEELLSQL RDVRKPDGST EHVGPILVGW LPCLSSYDSY CSNQVAAKAL LDHKKQDHRV 
QDFLQRCLES PFSRKLDLWN FLDIPRSRLV KYPLLLREIL RHTPNDNPDQ QHLEEAINII 
QGIVAEINTK TGESECRYYK ERLLYLEEGQ KDSLIDSSRV VCCHGELKNN RGVKLHVFLF 
QEVLVITRAV THNEQLCYQL YRQPIPVKDL LLEDLQDGEV RLGGSLRGAF SNNERIKNFF 
RVSFKNGSQS QTHSLQANDT FNKQQWLNCI RQAKETVLCA AGQAGVLDSE GSFLNPTTGS 
RELQGETKLE QMDQSDSESD CSMDTSEVSL DCERMEQTDS SCGNSRHGES NV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.