Details for: KCNK4

Gene ID: 50801

Symbol: KCNK4

Ensembl ID: ENSG00000182450

Description: potassium two pore domain channel subfamily K member 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.0196
    Cell Significance Index: 22.3300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.3382
    Cell Significance Index: 9.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2779
    Cell Significance Index: 38.1700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2402
    Cell Significance Index: 48.1900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.1554
    Cell Significance Index: -0.3400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1389
    Cell Significance Index: 9.3400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0967
    Cell Significance Index: 3.6600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0909
    Cell Significance Index: 4.0200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.0622
    Cell Significance Index: 0.8300
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.0533
    Cell Significance Index: 0.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0479
    Cell Significance Index: 17.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0402
    Cell Significance Index: 2.1100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0369
    Cell Significance Index: 25.5200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0326
    Cell Significance Index: 0.2200
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.0179
    Cell Significance Index: 0.1700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0054
    Cell Significance Index: 0.9800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0048
    Cell Significance Index: 0.1200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0022
    Cell Significance Index: 0.1100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.0018
    Cell Significance Index: 0.0100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0011
    Cell Significance Index: 0.0300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0004
    Cell Significance Index: -0.1900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0043
    Cell Significance Index: -0.1800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0047
    Cell Significance Index: -3.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0047
    Cell Significance Index: -3.4900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0050
    Cell Significance Index: -3.7900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0051
    Cell Significance Index: -2.8100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0056
    Cell Significance Index: -3.1800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0077
    Cell Significance Index: -0.4300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0088
    Cell Significance Index: -0.2800
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.0095
    Cell Significance Index: -0.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0117
    Cell Significance Index: -2.3300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0118
    Cell Significance Index: -3.4000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0159
    Cell Significance Index: -0.5200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0161
    Cell Significance Index: -0.2300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0169
    Cell Significance Index: -3.5500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0180
    Cell Significance Index: -3.0800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0192
    Cell Significance Index: -1.1800
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.0200
    Cell Significance Index: -0.0500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0227
    Cell Significance Index: -2.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0234
    Cell Significance Index: -2.8800
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: -0.0250
    Cell Significance Index: -0.2100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0254
    Cell Significance Index: -0.8900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0260
    Cell Significance Index: -2.6600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0264
    Cell Significance Index: -0.2500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0268
    Cell Significance Index: -1.2500
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -0.0272
    Cell Significance Index: -0.2800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0274
    Cell Significance Index: -0.5500
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0278
    Cell Significance Index: -0.3900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0282
    Cell Significance Index: -0.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0283
    Cell Significance Index: -3.2400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0305
    Cell Significance Index: -3.5600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0308
    Cell Significance Index: -0.3500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0310
    Cell Significance Index: -0.3900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0310
    Cell Significance Index: -1.3500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0321
    Cell Significance Index: -0.6400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0322
    Cell Significance Index: -2.4700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0330
    Cell Significance Index: -0.7000
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.0351
    Cell Significance Index: -0.4600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0360
    Cell Significance Index: -0.4200
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0374
    Cell Significance Index: -0.4100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0429
    Cell Significance Index: -1.0700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron (CL4030065)
    Fold Change: -0.0440
    Cell Significance Index: -0.4600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0456
    Cell Significance Index: -1.2400
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: -0.0469
    Cell Significance Index: -0.4500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0475
    Cell Significance Index: -3.7600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0518
    Cell Significance Index: -0.6900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0533
    Cell Significance Index: -1.2900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0546
    Cell Significance Index: -1.1400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0548
    Cell Significance Index: -1.0700
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0571
    Cell Significance Index: -0.6300
  • Cell Name: respiratory suprabasal cell (CL4033048)
    Fold Change: -0.0579
    Cell Significance Index: -0.5200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0583
    Cell Significance Index: -1.2200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0586
    Cell Significance Index: -1.2200
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.0586
    Cell Significance Index: -0.5300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0596
    Cell Significance Index: -2.8000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0598
    Cell Significance Index: -2.1000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0601
    Cell Significance Index: -0.6600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0605
    Cell Significance Index: -1.4500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0618
    Cell Significance Index: -0.6400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0644
    Cell Significance Index: -0.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0657
    Cell Significance Index: -3.4200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0665
    Cell Significance Index: -1.1200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0673
    Cell Significance Index: -2.4700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0690
    Cell Significance Index: -0.8600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.0701
    Cell Significance Index: -0.7300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0702
    Cell Significance Index: -3.1800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0716
    Cell Significance Index: -1.5300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0753
    Cell Significance Index: -2.1700
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.0770
    Cell Significance Index: -0.8400
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: -0.0773
    Cell Significance Index: -0.1000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0813
    Cell Significance Index: -1.6000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0816
    Cell Significance Index: -1.0300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0840
    Cell Significance Index: -1.4400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0850
    Cell Significance Index: -1.4700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0887
    Cell Significance Index: -1.1200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0901
    Cell Significance Index: -2.2500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0941
    Cell Significance Index: -1.9200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0988
    Cell Significance Index: -2.4100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0992
    Cell Significance Index: -2.6500
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1068
    Cell Significance Index: -2.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** KCNK4 is a member of the potassium channel subfamily K, which is characterized by its two-pore domain structure. This unique structure allows KCNK4 to regulate the flow of potassium ions across cell membranes, influencing various cellular processes. The gene is expressed in numerous cell types, including Purkinje cells, hippocampal pyramidal neurons, and Langerhans cells, highlighting its widespread distribution in the human body. **Pathways and Functions** KCNK4 is involved in several key pathways, including: 1. **Cardiac Conduction**: KCNK4 channels contribute to the regulation of cardiac action potentials, ensuring proper heart rhythm and function. 2. **Sensory Perception**: KCNK4 channels are involved in the detection of mechanical stimuli, such as touch and pain, and temperature changes. 3. **Neuronal Activity**: KCNK4 channels regulate neuronal excitability and action potentials in various brain regions, including the hippocampus and cerebral cortex. 4. **Muscle Contraction**: KCNK4 channels contribute to muscle contraction by regulating the influx of potassium ions. **Functions** The primary functions of KCNK4 channels include: 1. **Regulation of Ion Balance**: KCNK4 channels help maintain the balance of potassium ions across cell membranes, which is essential for various cellular processes. 2. **Sensory Transduction**: KCNK4 channels enable the detection of mechanical and thermal stimuli, allowing the body to respond to changes in its environment. 3. **Neuronal Communication**: KCNK4 channels facilitate communication between neurons, enabling the transmission of electrical signals. **Clinical Significance** Dysregulation of KCNK4 channels has been implicated in various neurological and cardiovascular disorders, including: 1. **Neurological Disorders**: KCNK4 channel dysfunction has been linked to conditions such as epilepsy, Parkinson's disease, and multiple sclerosis. 2. **Cardiovascular Disorders**: KCNK4 channel dysfunction has been implicated in cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. 3. **Pain Disorders**: KCNK4 channel dysfunction has been linked to chronic pain conditions, such as neuropathic pain. In conclusion, KCNK4 is a crucial gene that plays a vital role in regulating various physiological processes. Its dysregulation has been implicated in numerous neurological and cardiovascular disorders, highlighting the importance of understanding its functions and mechanisms of action. Further research is needed to fully elucidate the clinical significance of KCNK4 and its potential therapeutic applications.

Genular Protein ID: 3134871676

Symbol: KCNK4_HUMAN

Name: Potassium channel subfamily K member 4

UniProtKB Accession Codes:

Q9NYG8 B5TJL1 Q96T94

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 17 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PRINTS 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 11042359

Title: Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel.

PubMed ID: 11042359

DOI: 10.1016/s0169-328x(00)00183-2

PubMed ID: 10767409

Title: Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel.

PubMed ID: 10767409

DOI: 10.1016/s0014-5793(00)01388-0

PubMed ID: 12191490

Title: Cloning of two transcripts, HKT4.1a and HKT4.1b, from the human two-pore K+ channel gene KCNK4. Chromosomal localization, tissue distribution and functional expression.

PubMed ID: 12191490

DOI: 10.1016/s0169-328x(02)00157-2

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 26919430

Title: A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.

PubMed ID: 26919430

DOI: 10.1016/j.cell.2016.02.002

PubMed ID: 28693035

Title: K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.

PubMed ID: 28693035

DOI: 10.1038/nature22988

PubMed ID: 38605031

Title: Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2.

PubMed ID: 38605031

DOI: 10.1038/s41467-024-47208-5

PubMed ID: 30290154

Title: Mutations in KCNK4 that affect gating cause a recognizable neurodevelopmental syndrome.

PubMed ID: 30290154

DOI: 10.1016/j.ajhg.2018.09.001

PubMed ID: 22282805

Title: Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel.

PubMed ID: 22282805

DOI: 10.1126/science.1213808

PubMed ID: 23341632

Title: Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.

PubMed ID: 23341632

DOI: 10.1073/pnas.1218950110

PubMed ID: 25471887

Title: Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.

PubMed ID: 25471887

DOI: 10.1038/nature14013

PubMed ID: 25500157

Title: Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.

PubMed ID: 25500157

DOI: 10.1016/j.neuron.2014.11.017

PubMed ID: 34390650

Title: Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK.

PubMed ID: 34390650

DOI: 10.1016/j.neuron.2021.07.009

Sequence Information:

  • Length: 393
  • Mass: 42704
  • Checksum: 7F18E53A0A9AD57D
  • Sequence:
    • MRSTTLLALL ALVLLYLVSG ALVFRALEQP HEQQAQRELG EVREKFLRAH PCVSDQELGL 
LIKEVADALG GGADPETNST SNSSHSAWDL GSAFFFSGTI ITTIGYGNVA LRTDAGRLFC 
IFYALVGIPL FGILLAGVGD RLGSSLRHGI GHIEAIFLKW HVPPELVRVL SAMLFLLIGC 
LLFVLTPTFV FCYMEDWSKL EAIYFVIVTL TTVGFGDYVA GADPRQDSPA YQPLVWFWIL 
LGLAYFASVL TTIGNWLRVV SRRTRAEMGG LTAQAASWTG TVTARVTQRA GPAAPPPEKE 
QPLLPPPPCP AQPLGRPRSP SPPEKAQPPS PPTASALDYP SENLAFIDES SDTQSERGCP 
LPRAPRGRRR PNPPRKPVRP RGPGRPRDKG VPV

Genular Protein ID: 2110045130

Symbol: Q2YDA1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2YDA1

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 455
  • Mass: 49232
  • Checksum: ECB73347048833DD
  • Sequence:
    • VHASVHTRVR GLWVPWRGRH AHGGRGCRGV CGECRWVTTA PQEPPARPLQ AGSGAGPAPG 
RAMRSTTLLA LLALVLLYLV SGALVFRALE QPHEQQAQRE LGEVREKFLR AHPCVSDQEL 
GLLIKEVADA LGGGADPETN STSNSSHSAW DLGSAFFFSG TIITTIGYGN VALRTDAGRL 
FCIFYALVGI PLFGILLAGV GDRLGSSLRH GIGHIEAIFL KWHVPPELVR VLSAMLFLLI 
GCLLFVLTPT FVFCYMEDWS KLEAIYFVIV TLTTVGFGDY VAGADPRQDS PAYQPLVWFW 
ILLGLAYFAS VLTTIGNWLR VVSRRTRAEM GGLTAQAASW TGTVTARVTQ RAGPAAPPPE 
KEQPLLPPPP CPAQPLGRPR SPSPPEKAQL PSPPTASALD YPSENLAFID ESSDTQSERG 
CPLPRAPRGR RRPNPPRKPV RPRGPGRPRD KGVPV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.