Details for: NOSIP
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 233.0512
Cell Significance Index: -36.2500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 144.5731
Cell Significance Index: -36.6700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 109.3396
Cell Significance Index: -44.4200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 104.2526
Cell Significance Index: -49.2200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 97.3006
Cell Significance Index: -50.0500 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 73.3955
Cell Significance Index: -49.2500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 47.0598
Cell Significance Index: -44.9300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 34.2754
Cell Significance Index: -42.2600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.6813
Cell Significance Index: -46.1000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 11.5012
Cell Significance Index: -30.8100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.3599
Cell Significance Index: -31.8200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.3296
Cell Significance Index: -18.2300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 3.7792
Cell Significance Index: 261.3500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 3.1361
Cell Significance Index: 92.1100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.0713
Cell Significance Index: 124.3500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.3493
Cell Significance Index: 35.4800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.2092
Cell Significance Index: 660.4000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.0013
Cell Significance Index: 137.5100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.9093
Cell Significance Index: 58.6700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.8227
Cell Significance Index: 38.3600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8065
Cell Significance Index: 79.7800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.7352
Cell Significance Index: 132.5300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.6994
Cell Significance Index: 31.7000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6825
Cell Significance Index: 80.4900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.6642
Cell Significance Index: 23.0800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.6441
Cell Significance Index: 30.2700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.6258
Cell Significance Index: 80.2200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6148
Cell Significance Index: 75.5900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5494
Cell Significance Index: 242.9100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5470
Cell Significance Index: 11.4500 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.5184
Cell Significance Index: 1.5800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.4779
Cell Significance Index: 25.0900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4630
Cell Significance Index: 10.0300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4533
Cell Significance Index: 89.9600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.4326
Cell Significance Index: 11.5500 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.4231
Cell Significance Index: 54.6600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3559
Cell Significance Index: 18.5400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3502
Cell Significance Index: 66.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3443
Cell Significance Index: 69.0600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3430
Cell Significance Index: 25.5600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3124
Cell Significance Index: 53.3500 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.2394
Cell Significance Index: 2.7200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1957
Cell Significance Index: 13.8400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1855
Cell Significance Index: 167.4800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1681
Cell Significance Index: 4.5800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1583
Cell Significance Index: 2.1600 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.1578
Cell Significance Index: 1.2600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1033
Cell Significance Index: 37.0600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0736
Cell Significance Index: 50.8800 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.0671
Cell Significance Index: 0.7300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0328
Cell Significance Index: 1.0500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0166
Cell Significance Index: 0.8600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0125
Cell Significance Index: 0.2100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0125
Cell Significance Index: 0.3500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0082
Cell Significance Index: -15.4100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0163
Cell Significance Index: -11.9300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0196
Cell Significance Index: -36.1200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0200
Cell Significance Index: -15.1300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0239
Cell Significance Index: -36.7700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0285
Cell Significance Index: -38.7100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0333
Cell Significance Index: -3.4000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0488
Cell Significance Index: -36.1500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0490
Cell Significance Index: -31.1500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0621
Cell Significance Index: -28.1900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0719
Cell Significance Index: -40.5600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0855
Cell Significance Index: -53.4000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0885
Cell Significance Index: -3.1100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1197
Cell Significance Index: -9.1900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1282
Cell Significance Index: -36.8800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2075
Cell Significance Index: -3.8400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2266
Cell Significance Index: -26.4100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2305
Cell Significance Index: -14.5300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2457
Cell Significance Index: -35.7200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2470
Cell Significance Index: -28.3000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2482
Cell Significance Index: -6.3400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2576
Cell Significance Index: -54.2600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.2630
Cell Significance Index: -4.6500 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: -0.3441
Cell Significance Index: -3.4500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3842
Cell Significance Index: -21.5600 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.4078
Cell Significance Index: -7.0300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4196
Cell Significance Index: -25.7900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.4196
Cell Significance Index: -10.4900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4364
Cell Significance Index: -45.4400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.4522
Cell Significance Index: -7.7500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4992
Cell Significance Index: -39.5400 - Cell Name: peg cell (CL4033014)
Fold Change: -0.5194
Cell Significance Index: -12.0000 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.5560
Cell Significance Index: -7.1200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5889
Cell Significance Index: -39.6000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.6088
Cell Significance Index: -15.6500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.6268
Cell Significance Index: -16.8000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6275
Cell Significance Index: -38.4700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6309
Cell Significance Index: -18.0900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.6527
Cell Significance Index: -7.7800 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.6621
Cell Significance Index: -4.0000 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.6675
Cell Significance Index: -3.6400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.6800
Cell Significance Index: -19.5900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.6975
Cell Significance Index: -7.2200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.7109
Cell Significance Index: -20.9400 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.7814
Cell Significance Index: -10.9600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.8215
Cell Significance Index: -7.5700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 397194866
Symbol: NOSIP_HUMAN
Name: Nitric oxide synthase-interacting protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11149895
Title: NOSIP, a novel modulator of endothelial nitric oxide synthase activity.
PubMed ID: 11149895
PubMed ID: 10810093
Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.
PubMed ID: 10810093
DOI: 10.1101/gr.10.5.703
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15548660
Title: Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity.
PubMed ID: 15548660
PubMed ID: 16135813
Title: Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton.
PubMed ID: 16135813
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 301
- Mass: 33172
- Checksum: FB77D6E31511C884
- Sequence:
MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP DGYLYEREAI LEYILHQKKE IARQMKAYEK QRGTRREEQK ELQRAASQDH VRGFLEKESA IVSRPLNPFT AKALSGTSPD DVQPGPSVGP PSKDKDKVLP SFWIPSLTPE AKATKLEKPS RTVTCPMSGK PLRMSDLTPV HFTPLDSSVD RVGLITRSER YVCAVTRDSL SNATPCAVLR PSGAVVTLEC VEKLIRKDMV DPVTGDKLTD RDIIVLQRGG TGFAGSGVKL QAEKSRPVMQ A
Genular Protein ID: 2890121548
Symbol: A0A075B6F9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 304
- Mass: 33431
- Checksum: 918126FDC655775B
- Sequence:
MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP DGYLYEREAI LEYILHQKKE IARQMKAYEK QRGTRREEQK ELQRAASQDH VRGFLEKESA IVSRPLNPFT AKALSGTSPG DSDDVQPGPS VGPPSKDKDK VLPSFWIPSL TPEAKATKLE KPSRTVTCPM SGKPLRMSDL TPVHFTPLDS SVDRVGLITR SERYVCAVTR DSLSNATPCA VLRPSGAVVT LECVEKLIRK DMVDPVTGDK LTDRDIIVLQ RGGTGFAGSG VKLQAEKSRP VMQA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.