Details for: SH3GLB1

Gene ID: 51100

Symbol: SH3GLB1

Ensembl ID: ENSG00000097033

Description: SH3 domain containing GRB2 like, endophilin B1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 469.8955
    Cell Significance Index: -73.0900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 280.9456
    Cell Significance Index: -71.2600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 206.6768
    Cell Significance Index: -85.1400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 168.9392
    Cell Significance Index: -79.7600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 156.3788
    Cell Significance Index: -63.5300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 143.6861
    Cell Significance Index: -73.9100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 118.8932
    Cell Significance Index: -79.7800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 67.2956
    Cell Significance Index: -64.2500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 62.7273
    Cell Significance Index: -77.3400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 24.2305
    Cell Significance Index: -64.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 19.9769
    Cell Significance Index: -78.8300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.9654
    Cell Significance Index: -55.1800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.6647
    Cell Significance Index: -32.1000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.8106
    Cell Significance Index: 146.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.2462
    Cell Significance Index: 104.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.0565
    Cell Significance Index: 370.7200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.9455
    Cell Significance Index: 239.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6057
    Cell Significance Index: 322.1000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.5988
    Cell Significance Index: 75.1400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1679
    Cell Significance Index: 31.7900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1086
    Cell Significance Index: 85.0800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.0088
    Cell Significance Index: 9.2900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9998
    Cell Significance Index: 691.5300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9128
    Cell Significance Index: 498.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8694
    Cell Significance Index: 119.3900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.8681
    Cell Significance Index: 383.8300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8593
    Cell Significance Index: 308.2200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8094
    Cell Significance Index: 49.7500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7280
    Cell Significance Index: 13.4600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6508
    Cell Significance Index: 129.1600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.6478
    Cell Significance Index: 18.5700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6391
    Cell Significance Index: 63.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6380
    Cell Significance Index: 33.1400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5824
    Cell Significance Index: 41.1900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5444
    Cell Significance Index: 40.5700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5267
    Cell Significance Index: 11.4100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5260
    Cell Significance Index: 67.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4699
    Cell Significance Index: 30.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4624
    Cell Significance Index: 25.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.4190
    Cell Significance Index: 49.4100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4041
    Cell Significance Index: 51.8000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.4011
    Cell Significance Index: 6.0100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3790
    Cell Significance Index: 64.7200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3784
    Cell Significance Index: 61.5400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3577
    Cell Significance Index: 68.0800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2752
    Cell Significance Index: 6.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1492
    Cell Significance Index: 4.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0865
    Cell Significance Index: 162.8400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.0346
    Cell Significance Index: 0.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0147
    Cell Significance Index: 6.6700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0101
    Cell Significance Index: 0.2700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0055
    Cell Significance Index: 3.5200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0042
    Cell Significance Index: 7.7100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0066
    Cell Significance Index: -10.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0114
    Cell Significance Index: -8.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0273
    Cell Significance Index: -17.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0317
    Cell Significance Index: -23.2200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0325
    Cell Significance Index: -24.5800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0388
    Cell Significance Index: -52.7300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0915
    Cell Significance Index: -9.3500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0923
    Cell Significance Index: -2.7100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0981
    Cell Significance Index: -55.3500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1250
    Cell Significance Index: -3.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1945
    Cell Significance Index: -40.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2203
    Cell Significance Index: -63.4000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2337
    Cell Significance Index: -27.2400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.2801
    Cell Significance Index: -1.6900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3050
    Cell Significance Index: -44.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3317
    Cell Significance Index: -9.2700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3460
    Cell Significance Index: -4.1300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3475
    Cell Significance Index: -15.3700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4062
    Cell Significance Index: -8.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4067
    Cell Significance Index: -46.5900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4322
    Cell Significance Index: -49.3300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4466
    Cell Significance Index: -16.9100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4520
    Cell Significance Index: -7.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.4632
    Cell Significance Index: -21.0000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4637
    Cell Significance Index: -31.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4747
    Cell Significance Index: -29.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5786
    Cell Significance Index: -30.3800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5997
    Cell Significance Index: -15.7700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6158
    Cell Significance Index: -12.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6245
    Cell Significance Index: -8.5200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.6738
    Cell Significance Index: -16.1600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6778
    Cell Significance Index: -70.5700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.7062
    Cell Significance Index: -24.8200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7236
    Cell Significance Index: -18.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7372
    Cell Significance Index: -23.6100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7511
    Cell Significance Index: -59.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7764
    Cell Significance Index: -26.9800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.9326
    Cell Significance Index: -16.4800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.9442
    Cell Significance Index: -13.9400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.0480
    Cell Significance Index: -17.9600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.1023
    Cell Significance Index: -29.4900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1993
    Cell Significance Index: -73.5300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.2593
    Cell Significance Index: -26.9200
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -1.2885
    Cell Significance Index: -20.7900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.2921
    Cell Significance Index: -33.0100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.4205
    Cell Significance Index: -41.8400
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.4489
    Cell Significance Index: -33.4800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SH3GLB1 is a member of the endophilin family, which is known for its involvement in the regulation of membrane dynamics and autophagy. The gene encodes a protein that contains a SH3 domain, a characteristic feature of proteins involved in cell signaling and membrane trafficking. SH3GLB1 is also known to interact with other proteins, such as ATG16L1, and is involved in the regulation of autophagosome assembly and membrane tubulation. The protein's expression is tightly regulated, with high levels observed in cells undergoing nutrient starvation or stress. **Pathways and Functions:** SH3GLB1 is involved in several key cellular pathways, including: 1. **Autophagy**: SH3GLB1 is a key regulator of autophagy, a process that involves the degradation and recycling of cellular components. The protein interacts with ATG16L1 to regulate autophagosome assembly and membrane tubulation. 2. **Apoptotic Process**: SH3GLB1 is also involved in the regulation of apoptosis, a process that involves the programmed death of cells. The protein's expression is upregulated in response to nutrient starvation, suggesting its role in promoting cell survival. 3. **Membrane Organization**: SH3GLB1 is involved in the regulation of membrane dynamics, including membrane fission and tubulation. The protein's expression is required for the proper organization of cellular membranes. 4. **Cytoskeleton Organization**: SH3GLB1 is also involved in the regulation of cytoskeleton organization, including the formation of cytoskeletal structures and the regulation of cellular motility. **Clinical Significance:** SH3GLB1 is an important gene that plays a critical role in maintaining cellular homeostasis and regulating cellular responses to nutrient starvation. Mutations in this gene have been implicated in several human diseases, including: 1. **Autophagy-related disorders**: SH3GLB1 mutations have been linked to autophagy-related disorders, such as Langerhans cell histiocytosis and Crohn's disease. 2. **Cancer**: SH3GLB1 expression is altered in various types of cancer, suggesting its role in tumorigenesis and cancer progression. 3. **Neurodegenerative disorders**: SH3GLB1 expression is altered in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, suggesting its role in regulating cellular homeostasis and survival. In conclusion, SH3GLB1 is an important gene that plays a critical role in regulating autophagy, cellular homeostasis, and cellular responses to nutrient starvation. Its dysregulation has been implicated in several human diseases, highlighting the need for further research into the molecular mechanisms underlying SH3GLB1 function and its role in human disease.

Genular Protein ID: 590810803

Symbol: SHLB1_HUMAN

Name: Endophilin-B1

UniProtKB Accession Codes:

Q9Y371 B4E182 Q5H8U5 Q9H3Z0 Q9NR47 Q9NYA9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EMDB 2 Ensembl 3 ExpressionAtlas 1 GO 30 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11161816

Title: SH3GLB, a new endophilin-related protein family featuring an SH3 domain.

PubMed ID: 11161816

DOI: 10.1006/geno.2000.6378

PubMed ID: 11259440

Title: Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax.

PubMed ID: 11259440

DOI: 10.1074/jbc.m101527200

PubMed ID: 12456676

Title: Characterization of endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.

PubMed ID: 12456676

DOI: 10.1074/jbc.m208568200

PubMed ID: 9455484

Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PubMed ID: 9455484

DOI: 10.1093/dnares/4.5.345

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11604418

Title: Generation of high curvature membranes mediated by direct endophilin bilayer interactions.

PubMed ID: 11604418

DOI: 10.1083/jcb.200107075

PubMed ID: 15452144

Title: Endophilin B1 is required for the maintenance of mitochondrial morphology.

PubMed ID: 15452144

DOI: 10.1083/jcb.200407046

PubMed ID: 16227588

Title: Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis.

PubMed ID: 16227588

DOI: 10.1128/mcb.25.21.9369-9382.2005

PubMed ID: 17891140

Title: Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

PubMed ID: 17891140

DOI: 10.1038/ncb1634

PubMed ID: 20643123

Title: A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.

PubMed ID: 20643123

DOI: 10.1016/j.yexcr.2010.07.008

PubMed ID: 21068542

Title: Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy.

PubMed ID: 21068542

DOI: 10.4161/auto.7.1.14015

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21499257

Title: Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease.

PubMed ID: 21499257

DOI: 10.1038/ncb2217

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 365
  • Mass: 40796
  • Checksum: 42C2AEA57A0B350E
  • Sequence:
    • MNIMDFNVKK LAADAGTFLS RAVQFTEEKL GQAEKTELDA HLENLLSKAE CTKIWTEKIM 
KQTEVLLQPN PNARIEEFVY EKLDRKAPSR INNPELLGQY MIDAGTEFGP GTAYGNALIK 
CGETQKRIGT ADRELIQTSA LNFLTPLRNF IEGDYKTIAK ERKLLQNKRL DLDAAKTRLK 
KAKAAETRNS SEQELRITQS EFDRQAEITR LLLEGISSTH AHHLRCLNDF VEAQMTYYAQ 
CYQYMLDLQK QLGSFPSNYL SNNNQTSVTP VPSVLPNAIG SSAMASTSGL VITSPSNLSD 
LKECSGSRKA RVLYDYDAAN STELSLLADE VITVFSVVGM DSDWLMGERG NQKGKVPITY 
LELLN

Genular Protein ID: 423042952

Symbol: A0A087WW40_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WW40

Database IDs:

ARBA 15 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 2 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 394
  • Mass: 44260
  • Checksum: 582F88829B394136
  • Sequence:
    • MNIMDFNVKK LAADAGTFLS RAVQFTEEKL GQAEKTELDA HLENLLSKAE CTKIWTEKIM 
KQTEVLLQPN PNARIEEFVY EKLDRKAPSR INNPELLGQY MIDAGTEFGP GTAYGNALIK 
CGETQKRIGT ADRELIQTSA LNFLTPLRNF IEGDYKTIAK ERKLLQNKRL DLDAAKTRLK 
KAKAAETRNS QLNSARLEGD NIMVNFSYML NFLHVKWLKS EQELRITQSE FDRQAEITRL 
LLEGISSTHA HHLRCLNDFV EAQMTYYAQC YQYMLDLQKQ LGSFPSNYLS NNNQTSVTPV 
PSVLPNAIGS SAMASTSGLV ITSPSNLSDL KECSGSRKAR VLYDYDAANS TELSLLADEV 
ITVFSVVGMD SDWLMGERGN QKGKVPITYL ELLN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.