Details for: FKBP11
Gene ID: 51303
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: FKBP11
Ensembl ID: ENSG00000134285
Description: FKBP prolyl isomerase 11
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 63.1rCSI 49.64%PRS 86.56
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CSI 58.01rCSI 59.39%PRS 88.43
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CSI 50.18rCSI 60.1%PRS 90.57
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CSI 45.02rCSI 59%PRS 93.17
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CSI 31.69rCSI 42.11%PRS 87.07
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CSI 20.2rCSI 14.5%PRS 93.16
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CSI 13.15rCSI 10.44%PRS 95.96
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CSI 13.11rCSI 15.66%PRS 94.72
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CSI 12.59rCSI 18.14%PRS 87.94
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CSI 11.76rCSI 13.23%PRS 93.25
-
CSI 11.69rCSI 18.56%PRS 89.67
-
CSI 11.32rCSI 50.93%PRS 94.93
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CSI 9.88rCSI 23.48%PRS 86.56
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CSI 9.31rCSI 8.26%PRS 79.83
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CSI 9.18rCSI 36.67%PRS 89.04
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CSI 8.05rCSI 7.33%PRS 92.39
-
CSI 8.01rCSI 34.62%PRS 88.18
-
CSI 7.91rCSI 8.27%PRS 79.6
-
CSI 7.46rCSI 16.35%PRS 86.82
-
CSI 7.26rCSI 5.45%PRS 95.45
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CSI 7.11rCSI 12.83%PRS 94.65
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CSI 7rCSI 19.62%PRS 88.22
-
CSI 6.24rCSI 6.54%PRS 85.07
-
CSI 5.98rCSI 11.53%PRS 96.04
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CSI 5.83rCSI 8.01%PRS 94.94
-
CSI 5.59rCSI 4.54%PRS 81.43
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CSI 5.57rCSI 5.81%PRS 81.32
-
CSI 5.45rCSI 5.44%PRS 75.95
-
CSI 5.36rCSI 3.73%PRS 93.91
-
CSI 5.21rCSI 14.23%PRS 88.54
-
CSI 5.2rCSI 4.17%PRS 93.13
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CSI 5.11rCSI 7.07%PRS 78.96
-
CSI 4.92rCSI 3.72%PRS 92.78
-
CSI 4.88rCSI 4.61%PRS 80.47
-
CSI 4.87rCSI 3.78%PRS 85.6
-
CSI 4.87rCSI 3.64%PRS 93.12
-
CSI 4.86rCSI 28.3%PRS 85.45
-
CSI 4.81rCSI 2.84%PRS 95
-
CSI 4.74rCSI 4.95%PRS 92.94
-
CSI 4.66rCSI 3.1%PRS 92.29
-
CSI 4.45rCSI 4.12%PRS 94.47
-
CSI 4.45rCSI 43.75%PRS 91.04
-
CSI 4.39rCSI 3.05%PRS 92.29
-
CSI 4.34rCSI 6.35%PRS 86.64
-
CSI 4.11rCSI 3.09%PRS 87.45
-
CSI 4.09rCSI 5.6%PRS 86.37
-
CSI 4.04rCSI 3.27%PRS 84.05
-
CSI 4rCSI 3.93%PRS 93.5
-
CSI 4rCSI 3.86%PRS 75.82
-
CSI 4rCSI 4.69%PRS 83.5
-
CSI 3.99rCSI 5.1%PRS 90.35
-
CSI 3.96rCSI 5.41%PRS 81.63
-
CSI 3.86rCSI 3.39%PRS 86.79
-
CSI 3.7rCSI 8.85%PRS 85.59
-
CSI 3.7rCSI 2.46%PRS 84.48
-
CSI 3.67rCSI 2.79%PRS 93.16
-
CSI 3.63rCSI 4.86%PRS 80.32
-
CSI 3.54rCSI 2.75%PRS 93.73
-
CSI 3.45rCSI 4.88%PRS 80.45
-
CSI 3.31rCSI 3.88%PRS 93.59
-
CSI 3.28rCSI 4.85%PRS 90.89
-
CSI 3.23rCSI 2.67%PRS 82.92
-
CSI 3.19rCSI 3.95%PRS 80.24
-
CSI 3.1rCSI 4.47%PRS 87.1
-
CSI 3.03rCSI 7.83%PRS 95.21
-
CSI 3rCSI 2.1%PRS 85.41
-
CSI 3rCSI 5.36%PRS 81.28
-
CSI 2.92rCSI 3.98%PRS 95.63
-
CSI 2.85rCSI 2.39%PRS 84.34
-
CSI 2.84rCSI 4.42%PRS 95.05
-
CSI 2.75rCSI 4.38%PRS 75.32
-
CSI 2.75rCSI 6.24%PRS 82.21
-
CSI 2.74rCSI 2.69%PRS 84.37
-
CSI 2.72rCSI 5.63%PRS 78.47
-
CSI 2.71rCSI 5.98%PRS 85.48
-
CSI 2.69rCSI 2.01%PRS 92.57
-
CSI 2.64rCSI 2.29%PRS 85.64
-
CSI 2.54rCSI 3.73%PRS 90.34
-
CSI 2.52rCSI 11.04%PRS 88.94
-
CSI 2.49rCSI 4.26%PRS 92.97
-
CSI 2.4rCSI 6.08%PRS 75.71
-
CSI 2.33rCSI 1.57%PRS 93.22
-
CSI 2.29rCSI 3.62%PRS 83.39
-
CSI 2.26rCSI 2.62%PRS 85.4
-
CSI 2.2rCSI 2.34%PRS 86.63
-
CSI 2.1rCSI 6.02%PRS 95.79
-
CSI 2.06rCSI 4.28%PRS 78.88
-
CSI 2.05rCSI 4.47%PRS 88.23
-
CSI 1.96rCSI 1.77%PRS 80.19
-
CSI 1.78rCSI 2.24%PRS 89.53
-
CSI 1.76rCSI 3.33%PRS 96.9
-
CSI 1.74rCSI 3.85%PRS 81.48
-
CSI 1.68rCSI 3.57%PRS 87.45
-
CSI 1.66rCSI 4.39%PRS 88.1
-
CSI 1.58rCSI 2.54%PRS 80.96
-
CSI 1.53rCSI 4.42%PRS 87.74
-
CSI 1.51rCSI 1.32%PRS 71.54
-
CSI 1.48rCSI 2.26%PRS 89.31
-
CSI 1.42rCSI 2.89%PRS 60.99
-
CSI 1.39rCSI 2.7%PRS 84.87
-
CSI 0.2rCSI 1.3%PRS 84.7%
-
CSI 0.3rCSI 7.9%PRS 63.2%
-
CSI 0.3rCSI 3.7%PRS 86.7%
-
CSI 0.4rCSI 9.9%PRS 62.6%
-
CSI 0.5rCSI 11.3%PRS 92.0%
-
CSI 0.8rCSI 5.2%PRS 87.9%
-
CSI 0.8rCSI 2.7%PRS 89.1%
-
CSI 0.8rCSI 4.6%PRS 86.6%
-
CSI 0.8rCSI 2.2%PRS 95.4%
-
CSI 0.8rCSI 1.4%PRS 49.2%
-
CSI 0.9rCSI 2.5%PRS 87.3%
-
CSI 1.0rCSI 5.2%PRS 94.3%
-
CSI 1.0rCSI 1.2%PRS 62.7%
-
CSI 1.0rCSI 5.4%PRS 88.8%
-
CSI 1.1rCSI 1.5%PRS 49.2%
-
CSI 1.1rCSI 5.0%PRS 96.7%
-
CSI 1.2rCSI 4.9%PRS 86.4%
-
CSI 1.2rCSI 12.8%PRS 89.0%
-
CSI 1.2rCSI 2.1%PRS 64.1%
-
CSI 1.2rCSI 2.9%PRS 96.5%
-
CSI 1.3rCSI 6.3%PRS 92.4%
-
CSI 1.3rCSI 4.7%PRS 95.0%
-
CSI 1.3rCSI 2.3%PRS 51.1%
-
CSI 1.3rCSI 3.7%PRS 77.2%
-
CSI 1.4rCSI 32.3%PRS 89.6%
-
CSI 1.4rCSI 1.4%PRS 85.6%
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CSI 1.4rCSI 7.0%PRS 92.8%
-
CSI 1.4rCSI 2.7%PRS 84.9%
-
CSI 1.4rCSI 2.9%PRS 61.0%
-
CSI 1.5rCSI 2.3%PRS 89.3%
-
CSI 1.5rCSI 1.3%PRS 71.5%
-
CSI 1.5rCSI 4.4%PRS 87.7%
-
CSI 1.6rCSI 2.5%PRS 81.0%
-
CSI 1.7rCSI 4.4%PRS 88.1%
-
CSI 1.7rCSI 3.6%PRS 87.5%
-
CSI 1.7rCSI 3.9%PRS 81.5%
-
CSI 1.8rCSI 3.3%PRS 96.9%
-
CSI 1.8rCSI 2.2%PRS 89.5%
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CSI 2.0rCSI 1.8%PRS 80.2%
-
CSI 2.1rCSI 4.5%PRS 88.2%
-
CSI 2.1rCSI 4.3%PRS 78.9%
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CSI 2.1rCSI 6.0%PRS 95.8%
-
CSI 2.2rCSI 2.3%PRS 86.6%
-
CSI 2.3rCSI 2.6%PRS 85.4%
-
CSI 2.3rCSI 3.6%PRS 83.4%
-
CSI 2.3rCSI 1.6%PRS 93.2%
-
CSI 2.4rCSI 6.1%PRS 75.7%
-
CSI 2.5rCSI 4.3%PRS 93.0%
-
CSI 2.5rCSI 11.0%PRS 88.9%
-
CSI 2.5rCSI 3.7%PRS 90.3%
-
CSI 2.6rCSI 2.3%PRS 85.6%
-
CSI 2.7rCSI 2.0%PRS 92.6%
-
CSI 2.7rCSI 6.0%PRS 85.5%
-
CSI 2.7rCSI 5.6%PRS 78.5%
-
CSI 2.7rCSI 2.7%PRS 84.4%
-
CSI 2.8rCSI 6.2%PRS 82.2%
-
CSI 2.8rCSI 4.4%PRS 75.3%
-
CSI 2.8rCSI 4.4%PRS 95.1%
-
CSI 2.9rCSI 2.4%PRS 84.3%
-
CSI 2.9rCSI 4.0%PRS 95.6%
-
CSI 3.0rCSI 5.4%PRS 81.3%
-
CSI 3.0rCSI 2.1%PRS 85.4%
-
CSI 3.0rCSI 7.8%PRS 95.2%
-
CSI 3.1rCSI 4.5%PRS 87.1%
-
CSI 3.2rCSI 4.0%PRS 80.2%
-
CSI 3.2rCSI 2.7%PRS 82.9%
-
CSI 3.3rCSI 4.9%PRS 90.9%
-
CSI 3.3rCSI 3.9%PRS 93.6%
-
CSI 3.5rCSI 4.9%PRS 80.5%
-
CSI 3.5rCSI 2.8%PRS 93.7%
-
CSI 3.6rCSI 4.9%PRS 80.3%
-
CSI 3.7rCSI 2.8%PRS 93.2%
-
CSI 3.7rCSI 2.5%PRS 84.5%
-
CSI 3.7rCSI 8.9%PRS 85.6%
-
CSI 3.9rCSI 3.4%PRS 86.8%
-
CSI 4.0rCSI 5.4%PRS 81.6%
-
CSI 4.0rCSI 5.1%PRS 90.4%
-
CSI 4.0rCSI 4.7%PRS 83.5%
-
CSI 4.0rCSI 3.9%PRS 75.8%
-
CSI 4.0rCSI 3.9%PRS 93.5%
-
CSI 4.0rCSI 3.3%PRS 84.1%
-
CSI 4.1rCSI 5.6%PRS 86.4%
-
CSI 4.1rCSI 3.1%PRS 87.5%
-
CSI 4.3rCSI 6.4%PRS 86.6%
-
CSI 4.4rCSI 3.1%PRS 92.3%
-
CSI 4.5rCSI 43.8%PRS 91.0%
-
CSI 4.5rCSI 4.1%PRS 94.5%
-
CSI 4.7rCSI 3.1%PRS 92.3%
-
CSI 4.7rCSI 5.0%PRS 92.9%
-
CSI 4.8rCSI 2.8%PRS 95.0%
-
CSI 4.9rCSI 28.3%PRS 85.5%
-
CSI 4.9rCSI 3.6%PRS 93.1%
-
CSI 4.9rCSI 3.8%PRS 85.6%
-
CSI 4.9rCSI 4.6%PRS 80.5%
-
CSI 4.9rCSI 3.7%PRS 92.8%
-
CSI 5.1rCSI 7.1%PRS 79.0%
-
CSI 5.2rCSI 4.2%PRS 93.1%
-
CSI 5.2rCSI 14.2%PRS 88.5%
-
CSI 5.4rCSI 3.7%PRS 93.9%
-
CSI 5.5rCSI 5.4%PRS 76.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1419477804
Symbol: FKB11_HUMAN
Name: Peptidyl-prolyl cis-trans isomerase FKBP11
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 201
- Mass: 22180
- Checksum: 586E430B9D2DC0A2
- Sequence:
MTLRPSLLPL HLLLLLLLSA AVCRAEAGLE TESPVRTLQV ETLVEPPEPC AEPAAFGDTL HIHYTGSLVD GRIIDTSLTR DPLVIELGQK QVIPGLEQSL LDMCVGEKRR AIIPSHLAYG KRGFPPSVPA DAVVQYDVEL IALIRANYWL KLVKGILPLV GMAMVPALLG LIGYHLYRKA NRPKVSKKKL KEEKRNKSKK K
Genular Protein ID: 2278854799
Symbol: E9PAR0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
Sequence Information:
- Length: 99
- Mass: 11168
- Checksum: 3FFA385BAA609381
- Sequence:
MCVGEKRRAI IPSHLAYGKR GFPPSVPADA VVQYDVELIA LIRANYWLKL VKGILPLVGM AMVPALLGLI GYHLYRKANR PKVSKKKLKE EKRNKSKKK