Details for: DDX41

Gene ID: 51428

Symbol: DDX41

Ensembl ID: ENSG00000183258

Description: DEAD-box helicase 41

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 98.4280
    Cell Significance Index: -15.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 61.0306
    Cell Significance Index: -15.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 43.9293
    Cell Significance Index: -20.7400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 43.3962
    Cell Significance Index: -17.6300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 30.8932
    Cell Significance Index: -20.7300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.6542
    Cell Significance Index: -17.8100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.5561
    Cell Significance Index: -19.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.6293
    Cell Significance Index: -15.0800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.0734
    Cell Significance Index: -20.0200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.1886
    Cell Significance Index: -4.7900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8997
    Cell Significance Index: 146.3200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7326
    Cell Significance Index: 661.4700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6541
    Cell Significance Index: 8.9300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.4921
    Cell Significance Index: 5.3500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.4900
    Cell Significance Index: 13.1300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.4840
    Cell Significance Index: 8.1000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4642
    Cell Significance Index: 24.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4555
    Cell Significance Index: 23.6600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4273
    Cell Significance Index: 19.3700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4034
    Cell Significance Index: 10.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4009
    Cell Significance Index: 27.7300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3962
    Cell Significance Index: 75.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3718
    Cell Significance Index: 23.9900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3468
    Cell Significance Index: 7.2600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3446
    Cell Significance Index: 9.6300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3391
    Cell Significance Index: 9.0700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.3386
    Cell Significance Index: 25.2400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3374
    Cell Significance Index: 7.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3265
    Cell Significance Index: 38.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3264
    Cell Significance Index: 40.1300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3245
    Cell Significance Index: 9.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3215
    Cell Significance Index: 44.1500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3095
    Cell Significance Index: 10.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2947
    Cell Significance Index: 53.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2842
    Cell Significance Index: 13.2500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2738
    Cell Significance Index: 3.1100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.2530
    Cell Significance Index: 2.0200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2518
    Cell Significance Index: 137.5000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2327
    Cell Significance Index: 6.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2263
    Cell Significance Index: 29.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2242
    Cell Significance Index: 99.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1980
    Cell Significance Index: 39.7200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1871
    Cell Significance Index: 24.1700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1807
    Cell Significance Index: 9.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1598
    Cell Significance Index: 11.3000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1412
    Cell Significance Index: 8.9000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1303
    Cell Significance Index: 90.0900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1179
    Cell Significance Index: 11.6600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1104
    Cell Significance Index: 21.9100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0928
    Cell Significance Index: 33.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0906
    Cell Significance Index: 2.4200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0899
    Cell Significance Index: 4.2300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0540
    Cell Significance Index: 1.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0440
    Cell Significance Index: 1.4100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0323
    Cell Significance Index: 0.9500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0242
    Cell Significance Index: 0.8500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0184
    Cell Significance Index: 0.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0048
    Cell Significance Index: -9.0500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0071
    Cell Significance Index: -5.4100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0074
    Cell Significance Index: -13.5700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0079
    Cell Significance Index: -12.1300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0093
    Cell Significance Index: -12.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0115
    Cell Significance Index: -1.1700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0117
    Cell Significance Index: -8.6100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0173
    Cell Significance Index: -0.3200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0212
    Cell Significance Index: -15.7100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0230
    Cell Significance Index: -14.6000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0296
    Cell Significance Index: -5.0600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0297
    Cell Significance Index: -0.7600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0305
    Cell Significance Index: -17.2000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0387
    Cell Significance Index: -17.5500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0398
    Cell Significance Index: -24.8800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0521
    Cell Significance Index: -15.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0737
    Cell Significance Index: -8.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0809
    Cell Significance Index: -9.2700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0836
    Cell Significance Index: -1.2500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1052
    Cell Significance Index: -15.2900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1078
    Cell Significance Index: -22.7000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1228
    Cell Significance Index: -3.0700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1748
    Cell Significance Index: -1.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1778
    Cell Significance Index: -10.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1882
    Cell Significance Index: -19.6000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2015
    Cell Significance Index: -13.5500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2077
    Cell Significance Index: -16.4500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2157
    Cell Significance Index: -16.5500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.2501
    Cell Significance Index: -4.4200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2549
    Cell Significance Index: -15.6300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2817
    Cell Significance Index: -15.8100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2904
    Cell Significance Index: -6.7100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3304
    Cell Significance Index: -9.4700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3445
    Cell Significance Index: -9.8300
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.3558
    Cell Significance Index: -2.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3771
    Cell Significance Index: -16.6800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.4014
    Cell Significance Index: -5.1400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4179
    Cell Significance Index: -9.1500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4317
    Cell Significance Index: -12.7200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4450
    Cell Significance Index: -16.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4478
    Cell Significance Index: -11.5100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4503
    Cell Significance Index: -16.5300
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.4513
    Cell Significance Index: -6.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DDX41 is a member of the DEAD-box helicase family, characterized by its ability to unwind double-stranded RNA and facilitate RNA processing. Its high sequence similarity to other DEAD-box helicases, such as DDX20 and DDX11, suggests that DDX41 may share similar functional properties. The protein's ability to bind to RNA and ATP is crucial for its enzymatic activity, which is essential for its role in regulating immune responses. **Pathways and Functions:** DDX41 is involved in multiple pathways, including: 1. **Apoptotic process:** DDX41 has been shown to play a role in regulating apoptosis, a process of programmed cell death essential for maintaining immune homeostasis. 2. **ATP binding and hydrolysis:** DDX41's ability to bind to ATP and hydrolyze it is crucial for its enzymatic activity, which is necessary for its role in regulating RNA processing. 3. **Cytosol and nucleus:** DDX41 is localized to both the cytosol and nucleus, where it can interact with RNA and other proteins to regulate gene expression. 4. **Immune system:** DDX41 is highly expressed in cells involved in innate and adaptive immunity, suggesting its critical role in regulating immune responses. 5. **Spliceosome complex:** DDX41 is a key component of the spliceosome complex, which is responsible for processing pre-mRNA and regulating gene expression. **Clinical Significance:** DDX41's role in regulating immune responses and cellular proliferation makes it an important gene in the context of various diseases. Some potential clinical implications of DDX41 include: 1. **Innate immune disorders:** Abnormalities in DDX41 expression may contribute to innate immune disorders, such as sepsis or chronic inflammatory diseases. 2. **Cancer:** DDX41's role in regulating cell proliferation and apoptosis makes it a potential target for cancer therapy. 3. **Autoimmune diseases:** DDX41's involvement in regulating immune responses may contribute to the development of autoimmune diseases, such as rheumatoid arthritis or lupus. 4. **Neurological disorders:** DDX41's expression in neurons and glial cells suggests its potential role in neurological disorders, such as Alzheimer's disease or multiple sclerosis. In conclusion, DDX41 is a multifaceted gene that plays a critical role in regulating immune responses, cellular proliferation, and RNA processing. Its expression in cells involved in immune function and its involvement in various pathways make it an important gene in the context of various diseases. Further research is necessary to fully understand the clinical significance of DDX41 and its potential therapeutic applications.

Genular Protein ID: 806102851

Symbol: DDX41_HUMAN

Name: Probable ATP-dependent RNA helicase DDX41

UniProtKB Accession Codes:

Q9UJV9 B2RDC8 Q96BK6 Q96K05 Q9NT96 Q9NW04

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 CarbonylDB 1 ChEBI 6 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 8 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 3 Rhea 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10607561

Title: Developmental and cell biological functions of the Drosophila DEAD-box protein abstrakt.

PubMed ID: 10607561

DOI: 10.1016/s0960-9822(00)80082-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25920683

Title: Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

PubMed ID: 25920683

DOI: 10.1016/j.ccell.2015.03.017

PubMed ID: 26030138

Title: Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

PubMed ID: 26030138

DOI: 10.1371/journal.pone.0128558

PubMed ID: 26712909

Title: Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.

PubMed ID: 26712909

DOI: 10.1182/blood-2015-10-676098

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 32703943

Title: Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy.

PubMed ID: 32703943

DOI: 10.1038/s41467-020-17452-6

PubMed ID: 20941364

Title: Comparative structural analysis of human DEAD-box RNA helicases.

PubMed ID: 20941364

DOI: 10.1371/journal.pone.0012791

Sequence Information:

  • Length: 622
  • Mass: 69838
  • Checksum: E0A328724E0DF99A
  • Sequence:
    • MEESEPERKR ARTDEVPAGG SRSEAEDEDD EDYVPYVPLR QRRQLLLQKL LQRRRKGAAE 
EEQQDSGSEP RGDEDDIPLG PQSNVSLLDQ HQHLKEKAEA RKESAKEKQL KEEEKILESV 
AEGRALMSVK EMAKGITYDD PIKTSWTPPR YVLSMSEERH ERVRKKYHIL VEGDGIPPPI 
KSFKEMKFPA AILRGLKKKG IHHPTPIQIQ GIPTILSGRD MIGIAFTGSG KTLVFTLPVI 
MFCLEQEKRL PFSKREGPYG LIICPSRELA RQTHGILEYY CRLLQEDSSP LLRCALCIGG 
MSVKEQMETI RHGVHMMVAT PGRLMDLLQK KMVSLDICRY LALDEADRMI DMGFEGDIRT 
IFSYFKGQRQ TLLFSATMPK KIQNFAKSAL VKPVTINVGR AGAASLDVIQ EVEYVKEEAK 
MVYLLECLQK TPPPVLIFAE KKADVDAIHE YLLLKGVEAV AIHGGKDQEE RTKAIEAFRE 
GKKDVLVATD VASKGLDFPA IQHVINYDMP EEIENYVHRI GRTGRSGNTG IATTFINKAC 
DESVLMDLKA LLLEAKQKVP PVLQVLHCGD ESMLDIGGER GCAFCGGLGH RITDCPKLEA 
MQTKQVSNIG RKDYLAHSSM DF

Genular Protein ID: 1645900496

Symbol: B3KRK2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KRK2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 5 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 GO 6 Gene3D 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 Rhea 1 SMART 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 496
  • Mass: 55410
  • Checksum: EE29D6F0C8CB30A8
  • Sequence:
    • MSVKEMAKGI TYDDPIKTSW TPPRYVLSMS EERHERVRKK YHILVEGDGI PPPIKSFKEM 
KFPAAILRGL KKKGIHHPTP IQIQGIPTIL SGRDMIGIAF TGSGKTLVFT LPVIMFCLEQ 
EKRLPFSKRE GPYGLIICPS RELARQTHGI LEYYCRLLQE DSSPLLRCAL CIGGMSVKEQ 
METIRHGVHM MVATPGRLMD LLQKKMVSLD ICRYLALDEA DRMIDMGFEG DIRTIFSYFK 
GQRQTLLFSA TMPKKIQNFA KSALVKPVTI NVGRAGAASL DVIQEVEYVK EEAKMVYLLE 
CLQKTPPPVL IFAEKKADVD AIHEYLLLKG VEAVAIHGGK DQEERTKAIE AFREGKKDVL 
VATDVASKGL DFPAIQHVIN YDMPEEIENY VHRIGRTGRS GNTGIATTFI NKACDESVLM 
DLKALLLEAK QKVPPVLQVL HCGDESMLDI GGERGCAFCG GLGHRITDCP KLEAMQTKQV 
SNIGRKDYLA HSSMDF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.