Details for: SRRT
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 165.0324
Cell Significance Index: -25.6700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 114.5703
Cell Significance Index: -29.0600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 83.9670
Cell Significance Index: -34.5900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 73.7097
Cell Significance Index: -34.8000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 71.6295
Cell Significance Index: -29.1000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 65.5929
Cell Significance Index: -33.7400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 51.8910
Cell Significance Index: -34.8200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 30.7098
Cell Significance Index: -29.3200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 26.1161
Cell Significance Index: -32.2000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.3887
Cell Significance Index: -27.8300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.4312
Cell Significance Index: -33.2700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.2311
Cell Significance Index: -22.2100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.3870
Cell Significance Index: -11.7900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.9650
Cell Significance Index: 26.8100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.7980
Cell Significance Index: 124.3400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0531
Cell Significance Index: 114.5500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.9276
Cell Significance Index: 109.3900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9232
Cell Significance Index: 25.8000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7913
Cell Significance Index: 714.5100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7694
Cell Significance Index: 20.5800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6771
Cell Significance Index: 134.3800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6421
Cell Significance Index: 18.5000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.6180
Cell Significance Index: 28.0100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.6029
Cell Significance Index: 16.4100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6027
Cell Significance Index: 74.1100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.5978
Cell Significance Index: 20.7800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5799
Cell Significance Index: 104.5400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.5517
Cell Significance Index: 14.7300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.5336
Cell Significance Index: 34.4300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5275
Cell Significance Index: 27.4000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.5095
Cell Significance Index: 32.1100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4627
Cell Significance Index: 21.7500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.4513
Cell Significance Index: 23.5100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.4341
Cell Significance Index: 59.6200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4016
Cell Significance Index: 80.5600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3983
Cell Significance Index: 8.6300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3960
Cell Significance Index: 216.2900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.3782
Cell Significance Index: 10.8400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3400
Cell Significance Index: 64.7000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3337
Cell Significance Index: 147.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3217
Cell Significance Index: 15.0000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2685
Cell Significance Index: 7.0600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2393
Cell Significance Index: 30.6800 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.2088
Cell Significance Index: 2.2700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1926
Cell Significance Index: 69.0900 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1832
Cell Significance Index: 23.6700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1789
Cell Significance Index: 10.0400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1724
Cell Significance Index: 4.3100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1691
Cell Significance Index: 3.5400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1511
Cell Significance Index: 9.2900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1508
Cell Significance Index: 104.3200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1328
Cell Significance Index: 9.9000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1153
Cell Significance Index: 11.4100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0515
Cell Significance Index: 1.3800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0399
Cell Significance Index: 2.8300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0333
Cell Significance Index: 5.6800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.0242
Cell Significance Index: 0.7100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0210
Cell Significance Index: 38.7100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0206
Cell Significance Index: 31.7300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0128
Cell Significance Index: 24.0500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0017
Cell Significance Index: 2.2700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0039
Cell Significance Index: -2.9300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0075
Cell Significance Index: -0.1600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0088
Cell Significance Index: -5.4800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0135
Cell Significance Index: -9.9300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0153
Cell Significance Index: -9.6900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0230
Cell Significance Index: -17.4500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0231
Cell Significance Index: -13.0300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0304
Cell Significance Index: -13.8100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0308
Cell Significance Index: -5.0100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0378
Cell Significance Index: -2.9000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0385
Cell Significance Index: -0.6500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0390
Cell Significance Index: -1.3700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0412
Cell Significance Index: -1.3200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0488
Cell Significance Index: -4.9900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0690
Cell Significance Index: -14.5300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0971
Cell Significance Index: -27.9400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1178
Cell Significance Index: -3.0100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1281
Cell Significance Index: -18.6200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1309
Cell Significance Index: -1.5600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1529
Cell Significance Index: -17.5200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1582
Cell Significance Index: -18.0600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1641
Cell Significance Index: -19.1200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1747
Cell Significance Index: -9.1800 - Cell Name: germ cell (CL0000586)
Fold Change: -0.2384
Cell Significance Index: -1.8000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3011
Cell Significance Index: -31.3500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.3133
Cell Significance Index: -2.8900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3313
Cell Significance Index: -22.2800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3502
Cell Significance Index: -15.4900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3641
Cell Significance Index: -28.8400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.4150
Cell Significance Index: -8.1000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4218
Cell Significance Index: -25.8600 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.4385
Cell Significance Index: -6.1500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4616
Cell Significance Index: -17.4800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4999
Cell Significance Index: -12.8500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.5115
Cell Significance Index: -6.5500 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.5678
Cell Significance Index: -10.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.6234
Cell Significance Index: -10.6800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6414
Cell Significance Index: -32.4100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.6546
Cell Significance Index: -15.7000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 587305656
Symbol: SRRT_HUMAN
Name: Serrate RNA effector molecule homolog
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11239002
Title: Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.
PubMed ID: 11239002
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17924679
Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
PubMed ID: 17924679
DOI: 10.1021/pr070152u
PubMed ID: 17693683
Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
PubMed ID: 17693683
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18086880
Title: ARS2 is a conserved eukaryotic gene essential for early mammalian development.
PubMed ID: 18086880
DOI: 10.1128/mcb.01565-07
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19632182
Title: Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.
PubMed ID: 19632182
PubMed ID: 19546234
Title: Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase.
PubMed ID: 19546234
DOI: 10.1128/mcb.00289-09
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20858735
Title: Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.
PubMed ID: 20858735
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 26382858
Title: mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.
PubMed ID: 26382858
DOI: 10.1038/ncomms9192
PubMed ID: 25662211
Title: Luzp4 defines a new mRNA export pathway in cancer cells.
PubMed ID: 25662211
DOI: 10.1093/nar/gkv070
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 30842217
Title: NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
PubMed ID: 30842217
Sequence Information:
- Length: 876
- Mass: 100666
- Checksum: EB3ABD1325EA98D9
- Sequence:
MGDSDDEYDR RRRDKFRRER SDYDRSRERD ERRRGDDWND REWDRGRERR SRGEYRDYDR NRRERFSPPR HELSPPQKRM RRDWDEHSSD PYHSGYEMPY AGGGGGPTYG PPQPWGHPDV HIMQHHVLPI QARLGSIAEI DLGVPPPVMK TFKEFLLSLD DSVDETEAVK RYNDYKLDFR RQQMQDFFLA HKDEEWFRSK YHPDEVGKRR QEARGALQNR LRVFLSLMET GWFDNLLLDI DKADAIVKML DAAVIKMEGG TENDLRILEQ EEEEEQAGKP GEPSKKEEGR AGAGLGDGER KTNDKDEKKE DGKQAENDSS NDDKTKKSEG DGDKEEKKED SEKEAKKSSK KRNRKHSGDD SFDEGSVSES ESESESGQAE EEKEEAEEAL KEKEKPKEEE WEKPKDAAGL ECKPRPLHKT CSLFMRNIAP NISRAEIISL CKRYPGFMRV ALSEPQPERR FFRRGWVTFD RSVNIKEICW NLQNIRLREC ELSPGVNRDL TRRVRNINGI TQHKQIVRND IKLAAKLIHT LDDRTQLWAS EPGTPPLPTS LPSQNPILKN ITDYLIEEVS AEEEELLGSS GGAPPEEPPK EGNPAEINVE RDEKLIKVLD KLLLYLRIVH SLDYYNTCEY PNEDEMPNRC GIIHVRGPMP PNRISHGEVL EWQKTFEEKL TPLLSVRESL SEEEAQKMGR KDPEQEVEKF VTSNTQELGK DKWLCPLSGK KFKGPEFVRK HIFNKHAEKI EEVKKEVAFF NNFLTDAKRP ALPEIKPAQP PGPAQILPPG LTPGLPYPHQ TPQGLMPYGQ PRPPILGYGA GAVRPAVPTG GPPYPHAPYG AGRGNYDAFR GQGGYPGKPR NRMVRGDPRA IVEYRDLDAP DDVDFF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.