Details for: ERAP1

Gene ID: 51752

Symbol: ERAP1

Ensembl ID: ENSG00000164307

Description: endoplasmic reticulum aminopeptidase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 142.4023
    Cell Significance Index: -22.1500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 82.1626
    Cell Significance Index: -20.8400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 60.1533
    Cell Significance Index: -24.7800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 51.2473
    Cell Significance Index: -24.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 51.1745
    Cell Significance Index: -20.7900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 45.9772
    Cell Significance Index: -23.6500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 35.9824
    Cell Significance Index: -24.1500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.9536
    Cell Significance Index: -20.9600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.6787
    Cell Significance Index: -23.0300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.6119
    Cell Significance Index: -23.0700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.8920
    Cell Significance Index: -23.2500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.5218
    Cell Significance Index: -16.9600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.5675
    Cell Significance Index: 50.1100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 1.9893
    Cell Significance Index: 25.0500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5340
    Cell Significance Index: 92.0900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.4140
    Cell Significance Index: 153.8000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.2987
    Cell Significance Index: 67.6500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2657
    Cell Significance Index: 1142.8700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1929
    Cell Significance Index: 194.0100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.1542
    Cell Significance Index: 7.8200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8847
    Cell Significance Index: 12.0700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8269
    Cell Significance Index: 63.4600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7436
    Cell Significance Index: 51.4300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7146
    Cell Significance Index: 141.8100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5359
    Cell Significance Index: 107.5100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5065
    Cell Significance Index: 13.5300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4797
    Cell Significance Index: 11.9900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4672
    Cell Significance Index: 13.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4391
    Cell Significance Index: 79.1600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4339
    Cell Significance Index: 53.3500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.4311
    Cell Significance Index: 9.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4135
    Cell Significance Index: 21.4800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3463
    Cell Significance Index: 9.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2779
    Cell Significance Index: 377.9100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2512
    Cell Significance Index: 386.6600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.2508
    Cell Significance Index: 6.1200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2432
    Cell Significance Index: 46.2800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2249
    Cell Significance Index: 6.0300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2231
    Cell Significance Index: 80.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1968
    Cell Significance Index: 362.9400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1823
    Cell Significance Index: 343.3000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1775
    Cell Significance Index: 78.4800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1724
    Cell Significance Index: 17.0500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1611
    Cell Significance Index: 88.0000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1489
    Cell Significance Index: 6.7500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1471
    Cell Significance Index: 20.2000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.1455
    Cell Significance Index: 2.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1356
    Cell Significance Index: 3.7900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1221
    Cell Significance Index: 2.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1150
    Cell Significance Index: 7.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0962
    Cell Significance Index: 5.9100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0934
    Cell Significance Index: 1.9900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0920
    Cell Significance Index: 4.2900
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.0834
    Cell Significance Index: 1.3500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0722
    Cell Significance Index: 49.9400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0665
    Cell Significance Index: 1.1200
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.0631
    Cell Significance Index: 0.5600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0353
    Cell Significance Index: 4.5300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0313
    Cell Significance Index: 19.8800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0255
    Cell Significance Index: 1.8000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0237
    Cell Significance Index: 2.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0148
    Cell Significance Index: 2.5300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0076
    Cell Significance Index: 0.3600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0082
    Cell Significance Index: -0.3100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0115
    Cell Significance Index: -5.2300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0176
    Cell Significance Index: -13.3200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0178
    Cell Significance Index: -0.9000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0222
    Cell Significance Index: -3.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0224
    Cell Significance Index: -16.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0244
    Cell Significance Index: -18.1100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0307
    Cell Significance Index: -0.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0358
    Cell Significance Index: -3.6600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0360
    Cell Significance Index: -1.2700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0381
    Cell Significance Index: -21.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0402
    Cell Significance Index: -25.1200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0447
    Cell Significance Index: -0.2700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0577
    Cell Significance Index: -0.8700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0645
    Cell Significance Index: -18.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0820
    Cell Significance Index: -4.6000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0824
    Cell Significance Index: -9.4500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0848
    Cell Significance Index: -10.9500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0896
    Cell Significance Index: -9.3300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0921
    Cell Significance Index: -1.3600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1111
    Cell Significance Index: -1.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1115
    Cell Significance Index: -3.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1143
    Cell Significance Index: -24.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1203
    Cell Significance Index: -8.0900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1241
    Cell Significance Index: -3.3200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1396
    Cell Significance Index: -2.5800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1413
    Cell Significance Index: -16.4700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1666
    Cell Significance Index: -4.2800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1702
    Cell Significance Index: -5.0000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1914
    Cell Significance Index: -3.2800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2123
    Cell Significance Index: -15.8200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2194
    Cell Significance Index: -13.8300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2428
    Cell Significance Index: -5.2600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2600
    Cell Significance Index: -3.7400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2605
    Cell Significance Index: -4.3600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2691
    Cell Significance Index: -7.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ERAP1 is a metalloprotease enzyme that belongs to the aminopeptidase family. It is localized to the endoplasmic reticulum (ER) and is responsible for removing N-terminal peptides from newly synthesized Class I MHC molecules. This process is essential for the proper folding and assembly of MHC molecules, which are then transported to the cell surface for antigen presentation. ERAP1's activity is regulated by the presence of zinc ions, which are required for its catalytic function. **Pathways and Functions:** ERAP1's primary function is to process and present antigens to the immune system through the following pathways: 1. **Antigen Processing and Presentation via Class I MHC:** ERAP1 removes N-terminal peptides from newly synthesized Class I MHC molecules, allowing them to be presented to CD8+ T cells. 2. **Antigen Processing and Presentation via Class I MHC:** ERAP1 also processes and presents endogenous peptides via Class I MHC, ensuring the proper presentation of self-antigens. 3. **Angiogenesis Regulation:** ERAP1 has been shown to positively regulate angiogenesis, a process critical for tumor growth and metastasis. **Clinical Significance:** ERAP1's dysregulation has been implicated in various diseases, including: 1. **Autoimmune Disorders:** ERAP1's role in antigen presentation and immune response regulation makes it a potential target for the treatment of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 2. **Cancer:** ERAP1's involvement in angiogenesis and tumor growth suggests its potential as a therapeutic target for cancer treatment. 3. **Infectious Diseases:** ERAP1's role in antigen processing and presentation via Class I MHC makes it a potential target for the treatment of infectious diseases, such as HIV and tuberculosis. In conclusion, ERAP1 is a critical gene involved in the processing and presentation of antigens to the immune system. Its dysregulation has been implicated in various diseases, highlighting the need for further research into its role in human health and disease.

Genular Protein ID: 2233465335

Symbol: ERAP1_HUMAN

Name: Endoplasmic reticulum aminopeptidase 1

UniProtKB Accession Codes:

Q9NZ08 O60278 Q6UWY6 Q8NEL4 Q8TAD0 Q9UHF8 Q9UKY2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 1 EMBL 8 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 14 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10220586

Title: Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase.

PubMed ID: 10220586

DOI: 10.1093/oxfordjournals.jbchem.a022371

PubMed ID: 11481040

Title: Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene.

PubMed ID: 11481040

DOI: 10.1093/oxfordjournals.jbchem.a002977

PubMed ID: 9628581

Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9628581

DOI: 10.1093/dnares/5.1.31

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11056387

Title: Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells.

PubMed ID: 11056387

DOI: 10.1093/oxfordjournals.jbchem.a022812

PubMed ID: 15908954

Title: Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

PubMed ID: 15908954

DOI: 10.1038/ni1208

PubMed ID: 16286653

Title: The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a 'molecular ruler' mechanism.

PubMed ID: 16286653

DOI: 10.1073/pnas.0500721102

PubMed ID: 18445477

Title: An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release.

PubMed ID: 18445477

DOI: 10.1016/j.bbrc.2008.04.103

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 21478864

Title: Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1.

PubMed ID: 21478864

DOI: 10.1038/nsmb.2021

Sequence Information:

  • Length: 941
  • Mass: 107235
  • Checksum: 22A0795C90155F04
  • Sequence:
    • MVFLPLKWSL ATMSFLLSSL LALLTVSTPS WCQSTEASPK RSDGTPFPWN KIRLPEYVIP 
VHYDLLIHAN LTTLTFWGTT KVEITASQPT STIILHSHHL QISRATLRKG AGERLSEEPL 
QVLEHPRQEQ IALLAPEPLL VGLPYTVVIH YAGNLSETFH GFYKSTYRTK EGELRILAST 
QFEPTAARMA FPCFDEPAFK ASFSIKIRRE PRHLAISNMP LVKSVTVAEG LIEDHFDVTV 
KMSTYLVAFI ISDFESVSKI TKSGVKVSVY AVPDKINQAD YALDAAVTLL EFYEDYFSIP 
YPLPKQDLAA IPDFQSGAME NWGLTTYRES ALLFDAEKSS ASSKLGITMT VAHELAHQWF 
GNLVTMEWWN DLWLNEGFAK FMEFVSVSVT HPELKVGDYF FGKCFDAMEV DALNSSHPVS 
TPVENPAQIR EMFDDVSYDK GACILNMLRE YLSADAFKSG IVQYLQKHSY KNTKNEDLWD 
SMASICPTDG VKGMDGFCSR SQHSSSSSHW HQEGVDVKTM MNTWTLQKGF PLITITVRGR 
NVHMKQEHYM KGSDGAPDTG YLWHVPLTFI TSKSDMVHRF LLKTKTDVLI LPEEVEWIKF 
NVGMNGYYIV HYEDDGWDSL TGLLKGTHTA VSSNDRASLI NNAFQLVSIG KLSIEKALDL 
SLYLKHETEI MPVFQGLNEL IPMYKLMEKR DMNEVETQFK AFLIRLLRDL IDKQTWTDEG 
SVSERMLRSQ LLLLACVHNY QPCVQRAEGY FRKWKESNGN LSLPVDVTLA VFAVGAQSTE 
GWDFLYSKYQ FSLSSTEKSQ IEFALCRTQN KEKLQWLLDE SFKGDKIKTQ EFPQILTLIG 
RNPVGYPLAW QFLRKNWNKL VQKFELGSSS IAHMVMGTTN QFSTRTRLEE VKGFFSSLKE 
NGSQLRCVQQ TIETIEENIG WMDKNFDKIR VWLQSEKLER M

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.