Details for: PPID

Gene ID: 5481

Symbol: PPID

Ensembl ID: ENSG00000171497

Description: peptidylprolyl isomerase D

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 207.5281
    Cell Significance Index: -32.2800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 117.8820
    Cell Significance Index: -29.9000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 74.8534
    Cell Significance Index: -35.3400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 74.0418
    Cell Significance Index: -30.0800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 52.9193
    Cell Significance Index: -35.5100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 31.5582
    Cell Significance Index: -30.1300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.8518
    Cell Significance Index: -34.3400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.7653
    Cell Significance Index: -26.1600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.8468
    Cell Significance Index: -34.9100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.9837
    Cell Significance Index: -21.4500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.3818
    Cell Significance Index: -9.5900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.1953
    Cell Significance Index: 35.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.6342
    Cell Significance Index: 470.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.6258
    Cell Significance Index: 189.4700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.4433
    Cell Significance Index: 86.6500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0787
    Cell Significance Index: 175.4500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7966
    Cell Significance Index: 159.8100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7038
    Cell Significance Index: 384.3800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6956
    Cell Significance Index: 44.8800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4868
    Cell Significance Index: 14.0300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4789
    Cell Significance Index: 65.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4143
    Cell Significance Index: 21.7500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3913
    Cell Significance Index: 270.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3796
    Cell Significance Index: 75.3400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3751
    Cell Significance Index: 13.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3711
    Cell Significance Index: 8.0400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3552
    Cell Significance Index: 22.3900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3413
    Cell Significance Index: 122.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3260
    Cell Significance Index: 58.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3058
    Cell Significance Index: 135.2100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2952
    Cell Significance Index: 266.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2900
    Cell Significance Index: 35.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2836
    Cell Significance Index: 33.4500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2753
    Cell Significance Index: 7.3500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2685
    Cell Significance Index: 12.6200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2499
    Cell Significance Index: 5.2300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1978
    Cell Significance Index: 13.9900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1959
    Cell Significance Index: 19.3800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1902
    Cell Significance Index: 36.1900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1485
    Cell Significance Index: 6.9300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1453
    Cell Significance Index: 18.6300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1191
    Cell Significance Index: 6.1900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0902
    Cell Significance Index: 2.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0786
    Cell Significance Index: 2.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0761
    Cell Significance Index: 12.9900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.0699
    Cell Significance Index: 0.7600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.0476
    Cell Significance Index: 0.4000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0470
    Cell Significance Index: 1.0000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0458
    Cell Significance Index: 1.6100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0240
    Cell Significance Index: 0.6700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0172
    Cell Significance Index: 1.0600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0148
    Cell Significance Index: 0.3900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0059
    Cell Significance Index: 11.1300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0065
    Cell Significance Index: -8.8500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0114
    Cell Significance Index: -21.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0122
    Cell Significance Index: -18.8500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0129
    Cell Significance Index: -9.4900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0136
    Cell Significance Index: -8.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0173
    Cell Significance Index: -12.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0209
    Cell Significance Index: -13.2800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0230
    Cell Significance Index: -17.3800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0387
    Cell Significance Index: -21.8400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0485
    Cell Significance Index: -22.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0572
    Cell Significance Index: -5.8400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0611
    Cell Significance Index: -7.9000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0646
    Cell Significance Index: -0.7700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0661
    Cell Significance Index: -5.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0687
    Cell Significance Index: -1.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0745
    Cell Significance Index: -2.3900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0940
    Cell Significance Index: -10.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0961
    Cell Significance Index: -20.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1143
    Cell Significance Index: -13.0900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1653
    Cell Significance Index: -24.0300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1962
    Cell Significance Index: -1.6000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2152
    Cell Significance Index: -16.0400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2332
    Cell Significance Index: -15.6800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2370
    Cell Significance Index: -6.3400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2462
    Cell Significance Index: -6.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2477
    Cell Significance Index: -13.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3095
    Cell Significance Index: -14.0300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3114
    Cell Significance Index: -16.2200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3274
    Cell Significance Index: -34.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3348
    Cell Significance Index: -8.3700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3449
    Cell Significance Index: -10.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3499
    Cell Significance Index: -27.7100
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.3841
    Cell Significance Index: -2.9000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3909
    Cell Significance Index: -10.4800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4073
    Cell Significance Index: -10.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4144
    Cell Significance Index: -9.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4502
    Cell Significance Index: -27.6000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4605
    Cell Significance Index: -13.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4863
    Cell Significance Index: -21.5100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5279
    Cell Significance Index: -5.4700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5545
    Cell Significance Index: -3.3500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5569
    Cell Significance Index: -21.0900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5873
    Cell Significance Index: -8.8000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5876
    Cell Significance Index: -10.0700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.6083
    Cell Significance Index: -6.9100
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.6306
    Cell Significance Index: -8.5100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6545
    Cell Significance Index: -8.9300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Catalytic Activity:** PPID's primary function is the catalysis of peptidylprolyl cis-trans isomerization, a process essential for protein folding and stability. 2. **Subcellular Localization:** PPID is predominantly found in the mitochondria, where it plays a critical role in regulating mitochondrial dynamics and function. 3. **Interactions with Other Proteins:** PPID interacts with a wide range of proteins, including heat shock proteins (Hsp70, Hsp90), transcription factors, and signaling molecules, modulating their activity and localization. 4. **Regulation of Apoptosis:** PPID has been implicated in the regulation of apoptosis, a process essential for maintaining tissue homeostasis and eliminating damaged or infected cells. **Pathways and Functions:** 1. **Apoptotic Process:** PPID modulates apoptosis by regulating the activity of pro-apoptotic and anti-apoptotic proteins, influencing the mitochondrial outer membrane permeabilization (MOMP) pathway. 2. **Chaperone-Mediated Protein Folding:** PPID assists in the folding of proteins into their native conformation, ensuring proper protein function and stability. 3. **Signaling Pathways:** PPID interacts with various signaling molecules, including nuclear receptors, transcription factors, and kinases, modulating their activity and influencing cellular responses to stress and stimuli. 4. **Viral Release from Host Cells:** PPID has been implicated in the regulation of viral release from host cells, influencing the replication and assembly of viruses. **Clinical Significance:** 1. **Cyclosporin A Binding:** PPID's interaction with cyclosporin A (CsA) has led to the development of CsA-based immunosuppressive therapies, which are used to prevent organ rejection in transplant patients. 2. **Mitochondrial Dysfunction:** PPID's role in regulating mitochondrial dynamics and function has implications for the diagnosis and treatment of mitochondrial disorders, such as mitochondrial myopathies and neurodegenerative diseases. 3. **Cancer and Apoptosis:** PPID's involvement in regulating apoptosis has led to its investigation as a potential therapeutic target in cancer treatment, where its modulation could enhance cancer cell death and reduce tumor growth. 4. **Neurodegenerative Diseases:** PPID's interaction with Hsp90 has led to its investigation as a potential therapeutic target in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where its modulation could influence protein folding and aggregation. In conclusion, PPID is a multifunctional protein that plays a critical role in various cellular processes, including apoptosis, protein folding, and signaling pathways. Its unique catalytic activity and interactions with other proteins make it a valuable target for the development of novel therapeutic strategies for various diseases, including cancer, mitochondrial disorders, and neurodegenerative diseases.

Genular Protein ID: 2423915075

Symbol: PPID_HUMAN

Name: 40 kDa peptidyl-prolyl cis-trans isomerase

UniProtKB Accession Codes:

Q08752 B2R9V2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 2 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 25 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 3 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8509368

Title: Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterization.

PubMed ID: 8509368

DOI: 10.1016/s0021-9258(18)31389-9

PubMed ID: 8812478

Title: The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene.

PubMed ID: 8812478

DOI: 10.1006/geno.1996.0384

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 9659917

Title: Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism.

PubMed ID: 9659917

DOI: 10.1016/s1097-2765(00)80021-0

PubMed ID: 11525244

Title: Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock.

PubMed ID: 11525244

DOI: 10.1379/1466-1268(2001)006<0059:hciahs>2.0.co;2

PubMed ID: 11350175

Title: Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40.

PubMed ID: 11350175

DOI: 10.1006/jmbi.2001.4595

PubMed ID: 12145316

Title: A structure-based mutational analysis of cyclophilin 40 identifies key residues in the core tetratricopeptide repeat domain that mediate binding to Hsp90.

PubMed ID: 12145316

DOI: 10.1074/jbc.m207097200

PubMed ID: 14580201

Title: High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients.

PubMed ID: 14580201

DOI: 10.1021/bi035001t

PubMed ID: 15497503

Title: Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70.

PubMed ID: 15497503

DOI: 10.1379/csc-26r.1

PubMed ID: 18708059

Title: Cyclophilin-40 has a cellular role in the aryl hydrocarbon receptor signaling.

PubMed ID: 18708059

DOI: 10.1016/j.febslet.2008.08.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20676357

Title: Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.

PubMed ID: 20676357

DOI: 10.1371/journal.pbio.1000439

PubMed ID: 19932913

Title: Multiple cyclophilins involved in different cellular pathways mediate HCV replication.

PubMed ID: 19932913

DOI: 10.1016/j.virol.2009.10.043

PubMed ID: 21146485

Title: Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40.

PubMed ID: 21146485

DOI: 10.1016/j.ab.2010.12.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21711559

Title: Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion.

PubMed ID: 21711559

DOI: 10.1186/1743-422x-8-329

PubMed ID: 22681779

Title: The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.

PubMed ID: 22681779

DOI: 10.1186/1471-2407-12-229

PubMed ID: 23220213

Title: Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes.

PubMed ID: 23220213

DOI: 10.1016/j.yexcr.2012.11.016

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 370
  • Mass: 40764
  • Checksum: 39D4100748B35D48
  • Sequence:
    • MSHPSPQAKP SNPSNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGIGH 
TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM 
ANAGRNTNGS QFFITTVPTP HLDGKHVVFG QVIKGIGVAR ILENVEVKGE KPAKLCVIAE 
CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LITEDLKNIG NTFFKSQNWE 
MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL 
ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK 
EKAVYAKMFA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.