Details for: ARID4A

Gene ID: 5926

Symbol: ARID4A

Ensembl ID: ENSG00000032219

Description: AT-rich interaction domain 4A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 384.7755
    Cell Significance Index: -59.8500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 224.3701
    Cell Significance Index: -56.9100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 153.1020
    Cell Significance Index: -63.0700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 138.3327
    Cell Significance Index: -65.3100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 126.0778
    Cell Significance Index: -51.2200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 116.6441
    Cell Significance Index: -60.0000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 97.4782
    Cell Significance Index: -65.4100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 54.0879
    Cell Significance Index: -51.6400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.9021
    Cell Significance Index: -62.7600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 21.4980
    Cell Significance Index: -57.5900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.3531
    Cell Significance Index: -64.5300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.8334
    Cell Significance Index: -45.5600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.4092
    Cell Significance Index: -24.9700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.8386
    Cell Significance Index: 299.0300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.7504
    Cell Significance Index: 107.5900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4184
    Cell Significance Index: 1280.7500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4033
    Cell Significance Index: 278.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2242
    Cell Significance Index: 439.1100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.1925
    Cell Significance Index: 28.6000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0719
    Cell Significance Index: 69.1600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0629
    Cell Significance Index: 115.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.0145
    Cell Significance Index: 53.2700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8625
    Cell Significance Index: 51.7800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8173
    Cell Significance Index: 565.2600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.8158
    Cell Significance Index: 36.0900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.7641
    Cell Significance Index: 42.8800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7447
    Cell Significance Index: 134.2600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.7030
    Cell Significance Index: 26.6200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6938
    Cell Significance Index: 46.6500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6152
    Cell Significance Index: 75.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5191
    Cell Significance Index: 66.5500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4990
    Cell Significance Index: 10.8100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4944
    Cell Significance Index: 67.9000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4365
    Cell Significance Index: 33.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4266
    Cell Significance Index: 12.2900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3985
    Cell Significance Index: 176.1800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3826
    Cell Significance Index: 19.9300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.3564
    Cell Significance Index: 8.9100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3384
    Cell Significance Index: 5.8000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2794
    Cell Significance Index: 152.5900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2266
    Cell Significance Index: 2.8100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.2055
    Cell Significance Index: 4.0100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1886
    Cell Significance Index: 18.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1633
    Cell Significance Index: 19.2600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1624
    Cell Significance Index: 305.8000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0739
    Cell Significance Index: 100.4700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0679
    Cell Significance Index: 125.2400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0656
    Cell Significance Index: 100.9900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0591
    Cell Significance Index: 37.5400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0517
    Cell Significance Index: 8.8300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0400
    Cell Significance Index: 8.0300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0280
    Cell Significance Index: 5.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0205
    Cell Significance Index: 9.3100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0047
    Cell Significance Index: -0.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0188
    Cell Significance Index: -13.9400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0211
    Cell Significance Index: -2.7300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0246
    Cell Significance Index: -18.0100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0261
    Cell Significance Index: -1.8100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0563
    Cell Significance Index: -35.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0631
    Cell Significance Index: -47.7300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0640
    Cell Significance Index: -36.1000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0860
    Cell Significance Index: -4.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0989
    Cell Significance Index: -4.6100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1170
    Cell Significance Index: -3.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1178
    Cell Significance Index: -12.0400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1560
    Cell Significance Index: -1.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1605
    Cell Significance Index: -33.8200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1692
    Cell Significance Index: -8.7900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1909
    Cell Significance Index: -54.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2029
    Cell Significance Index: -29.4900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2316
    Cell Significance Index: -14.6000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2737
    Cell Significance Index: -7.8100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2800
    Cell Significance Index: -9.8400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2839
    Cell Significance Index: -7.5800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3135
    Cell Significance Index: -36.5300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3338
    Cell Significance Index: -38.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3467
    Cell Significance Index: -39.7300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3982
    Cell Significance Index: -29.6800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4958
    Cell Significance Index: -51.6200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5368
    Cell Significance Index: -14.3600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6029
    Cell Significance Index: -19.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6619
    Cell Significance Index: -52.4200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.6919
    Cell Significance Index: -11.5800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.7052
    Cell Significance Index: -14.7600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.7348
    Cell Significance Index: -11.1600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.7385
    Cell Significance Index: -16.1700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7431
    Cell Significance Index: -19.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7508
    Cell Significance Index: -26.0900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.8236
    Cell Significance Index: -17.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.8243
    Cell Significance Index: -21.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9152
    Cell Significance Index: -56.1100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.0105
    Cell Significance Index: -27.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.1115
    Cell Significance Index: -50.3800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.1865
    Cell Significance Index: -30.3100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -1.1872
    Cell Significance Index: -17.8900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.1879
    Cell Significance Index: -20.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.1885
    Cell Significance Index: -34.9100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.2014
    Cell Significance Index: -34.4400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -1.2429
    Cell Significance Index: -9.5800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.2666
    Cell Significance Index: -23.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ARID4A is a member of the AT-rich interaction domain (ARID) family of proteins, which are known for their ability to bind to AT-rich DNA sequences. The ARID4A protein is characterized by its unique structure, which includes a DNA-binding domain, a helicase domain, and a histone deacetylase (HDAC) domain. This combination of domains enables ARID4A to regulate chromatin structure, histone modification, and gene expression. **Pathways and Functions:** ARID4A is involved in various cellular pathways, including: 1. **Chromatin modifying enzymes:** ARID4A regulates chromatin structure and histone modification by interacting with chromatin-modifying enzymes, such as HDACs and histone acetyltransferases (HATs). 2. **Chromatin organization:** ARID4A plays a crucial role in maintaining chromatin organization by regulating the assembly of nucleosomes and the formation of chromatin loops. 3. **Gene expression:** ARID4A regulates gene expression by controlling the recruitment of transcription factors and the assembly of transcriptional complexes. 4. **Immune regulation:** ARID4A is involved in immune regulation by modulating the expression of immune-related genes and influencing the activity of immune cells, such as T cells and dendritic cells. **Clinical Significance:** ARID4A has been implicated in various diseases, including: 1. **Immunodeficiency disorders:** Mutations in ARID4A have been associated with immunodeficiency disorders, such as severe combined immunodeficiency (SCID) and hyper-IgM syndrome. 2. **Cancer:** ARID4A has been found to be overexpressed in several types of cancer, including breast, ovarian, and lung cancer. 3. **Neurological disorders:** ARID4A has been implicated in neurological disorders, such as autism spectrum disorder and schizophrenia. 4. **SARS-CoV infections:** ARID4A has been identified as a potential therapeutic target for SARS-CoV infections, given its role in regulating immune responses. **Significantly Expressed Cells:** ARID4A is expressed in various cell types, including: 1. **GABAergic neurons:** ARID4A is expressed in GABAergic neurons, which are involved in regulating neurotransmitter release and synaptic plasticity. 2. **Astrocytes:** ARID4A is expressed in astrocytes, which are involved in maintaining the blood-brain barrier and regulating the immune response in the central nervous system. 3. **Ependymal cells:** ARID4A is expressed in ependymal cells, which are involved in producing cerebrospinal fluid and regulating the immune response in the central nervous system. **Proteins:** The ARID4A protein is also known as ARI4A_HUMAN, and it is encoded by the ENSG00000032219 gene. In conclusion, ARID4A is a multifunctional regulator that plays a crucial role in various cellular processes, including immune regulation, chromatin organization, and gene expression. Its clinical significance in diseases, such as immunodeficiency disorders, cancer, and neurological disorders, highlights the importance of understanding its role in maintaining immune homeostasis. Further research is needed to elucidate the complex mechanisms by which ARID4A regulates cellular processes and to identify potential therapeutic targets for diseases associated with ARID4A dysfunction.

Genular Protein ID: 4004831933

Symbol: ARI4A_HUMAN

Name: AT-rich interactive domain-containing protein 4A

UniProtKB Accession Codes:

P29374 Q15991 Q15992 Q15993

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8414517

Title: Characterization of the retinoblastoma binding proteins RBP1 and RBP2.

PubMed ID: 8414517

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 8455946

Title: Alternative splicing of the RBP1 gene clusters in an internal exon that encodes potential phosphorylation sites.

PubMed ID: 8455946

PubMed ID: 1857421

Title: Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product.

PubMed ID: 1857421

DOI: 10.1038/352251a0

PubMed ID: 14581478

Title: Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription.

PubMed ID: 14581478

DOI: 10.1074/jbc.m307969200

PubMed ID: 17043311

Title: Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain.

PubMed ID: 17043311

DOI: 10.1101/gad.1452206

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23487765

Title: ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.

PubMed ID: 23487765

DOI: 10.1073/pnas.1218318110

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 22247551

Title: Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1.

PubMed ID: 22247551

DOI: 10.1074/jbc.m111.299149

PubMed ID: 24379399

Title: Retinoblastoma-binding protein 1 has an interdigitated double Tudor domain with DNA binding activity.

PubMed ID: 24379399

DOI: 10.1074/jbc.m113.501940

PubMed ID: 29408527

Title: Crystal structure of chromo barrel domain of RBBP1.

PubMed ID: 29408527

DOI: 10.1016/j.bbrc.2018.02.016

Sequence Information:

  • Length: 1257
  • Mass: 142752
  • Checksum: 5B3F6A5AFB7588CF
  • Sequence:
    • MKAADEPAYL TVGTDVSAKY RGAFCEAKIK TVKRLVKVKV LLKQDNTTQL VQDDQVKGPL 
RVGAIVETRT SDGSFQEAII SKLTDASWYT VVFDDGDERT LRRTSLCLKG ERHFAESETL 
DQLPLTNPEH FGTPVIAKKT NRGRRSSLPV TEDEKEEESS EEEDEDKRRL NDELLGKVVS 
VVSATERTEW YPALVISPSC NDDITVKKDQ CLVRSFIDSK FYSIARKDIK EVDILNLPES 
ELSTKPGLQK ASIFLKTRVV PDNWKMDISE ILESSSSDDE DGPAEENDEE KEKEAKKTEE 
EVPEEELDPE ERDNFLQQLY KFMEDRGTPI NKPPVLGYKD LNLFKLFRLV YHQGGCDNID 
SGAVWKQIYM DLGIPILNSA ASYNVKTAYR KYLYGFEEYC RSANIQFRTV HHHEPKVKEE 
KKDLEESMEE ALKLDQEMPL TEVKSEPEEN IDSNSESERE EIELKSPRGR RRIARDVNSI 
KKEIEEEKTE DKLKDNDTEN KDVDDDYETA EKKENELLLG RKNTPKQKEK KIKKQEDSDK 
DSDEEEEKSQ EREETESKCD SEGEEDEEDM EPCLTGTKVK VKYGRGKTQK IYEASIKSTE 
IDDGEVLYLV HYYGWNVRYD EWVKADRIIW PLDKGGPKKK QKKKAKNKED SEKDEKRDEE 
RQKSKRGRPP LKSTLSSNMP YGLSKTANSE GKSDSCSSDS ETEDALEKNL INEELSLKDE 
LEKNENLNDD KLDEENPKIS AHILKENDRT QMQPLETLKL EVGENEQIVQ IFGNKMEKTE 
EVKKEAEKSP KGKGRRSKTK DLSLEIIKIS SFGQNEAGSE PHIEAHSLEL SSLDNKNFSS 
ATEDEIDQCV KEKKLKRKIL GQSSPEKKIR IENGMEMTNT VSQERTSDCI GSEGMKNLNF 
EQHFERENEG MPSLIAESNQ CIQQLTSERF DSPAEETVNI PLKEDEDAMP LIGPETLVCH 
EVDLDDLDEK DKTSIEDVAV ESSESNSLVS IPPALPPVVQ HNFSVASPLT LSQDESRSVK 
SESDITIEVD SIAEESQEGL CERESANGFE TNVASGTCSI IVQERESREK GQKRPSDGNS 
GLMAKKQKRT PKRTSAAAKN EKNGTGQSSD SEDLPVLDNS SKCTPVKHLN VSKPQKLARS 
PARISPHIKD GEKDKHREKH PNSSPRTYKW SFQLNELDNM NSTERISFLQ EKLQEIRKYY 
MSLKSEVATI DRRRKRLKKK DREVSHAGAS MSSASSDTGM SPSSSSPPQN VLAVECR

Genular Protein ID: 1681789160

Symbol: Q05CG0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q05CG0

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 3 SAM 1 SMART 3 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 424
  • Mass: 48479
  • Checksum: FEDB5BFE9E0DA1C5
  • Sequence:
    • MKAADEPAYL TVGTDVSAKY RGAFCEAKIK TVKRLVKVKV LLKQDNTTQL VQDDQVKGPL 
RVGAIVETRT SDGSFQEAII SKLTDASWYT VVFDDGDERT LRRTSLCLKG ERHFAESETL 
DQLPLTNPEH FGTPVIAKKT NRGRRSSLPV TEDEKEEESS EEEDEDKRRL NDELLGKVVS 
VVSATERTEW YPALVISPSC NDDITVKKDQ CLVRSFIDSK FYSIARKDIK EVDILNLPES 
ELSTKPGLQK ASIFLKTRVV PDNWKMDISE ILESSSSDDE DGPAEENDEE KEKEAKKTEE 
EVPEEELDPE ERDNFLQQLY KFMEDRGTPI NKPPVLGYKD LNLFKLFRLV YHQGGCDNID 
SGAVWKQIYM DLGIPILNSA ASYNVKTAYR KYLYGFEEYC RSANIQFRTV HHHEPKKKKK 
KKKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.