Details for: REL

Gene ID: 5966

Symbol: REL

Ensembl ID: ENSG00000162924

Description: REL proto-oncogene, NF-kB subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 297.4055
    Cell Significance Index: -46.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 161.9597
    Cell Significance Index: -41.0800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 118.1149
    Cell Significance Index: -47.9900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 107.9910
    Cell Significance Index: -50.9900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 100.0806
    Cell Significance Index: -51.4800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 75.9513
    Cell Significance Index: -50.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 50.8043
    Cell Significance Index: -48.5100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.9957
    Cell Significance Index: -48.0800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.6904
    Cell Significance Index: -47.3900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.3326
    Cell Significance Index: -48.6700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.9520
    Cell Significance Index: -36.7100
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 10.2353
    Cell Significance Index: 30.4400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.0065
    Cell Significance Index: -21.9000
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 3.4715
    Cell Significance Index: 59.6400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.7838
    Cell Significance Index: 79.8000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 2.6443
    Cell Significance Index: 56.3200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.6127
    Cell Significance Index: 48.2900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.5496
    Cell Significance Index: 300.6700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.3172
    Cell Significance Index: 120.3700
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 1.5592
    Cell Significance Index: 8.9400
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.3148
    Cell Significance Index: 5.8800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 1.3049
    Cell Significance Index: 34.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.2302
    Cell Significance Index: 221.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.1622
    Cell Significance Index: 513.8500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.1383
    Cell Significance Index: 53.5000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.0507
    Cell Significance Index: 74.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0235
    Cell Significance Index: 125.8500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9882
    Cell Significance Index: 107.4900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.8861
    Cell Significance Index: 114.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8481
    Cell Significance Index: 54.7200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7699
    Cell Significance Index: 20.9600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7632
    Cell Significance Index: 151.4500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7515
    Cell Significance Index: 6.9200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7343
    Cell Significance Index: 401.0200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6811
    Cell Significance Index: 50.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6515
    Cell Significance Index: 29.5300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6425
    Cell Significance Index: 580.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5357
    Cell Significance Index: 107.4700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.4864
    Cell Significance Index: 8.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4418
    Cell Significance Index: 60.6700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4138
    Cell Significance Index: 8.9700
  • Cell Name: centroblast (CL0009112)
    Fold Change: 0.2657
    Cell Significance Index: 0.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2541
    Cell Significance Index: 7.3200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2094
    Cell Significance Index: 5.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1880
    Cell Significance Index: 18.6000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1692
    Cell Significance Index: 32.2000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1551
    Cell Significance Index: 55.6400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1386
    Cell Significance Index: 95.8700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.1137
    Cell Significance Index: 0.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0906
    Cell Significance Index: 170.6100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0534
    Cell Significance Index: 4.1000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0399
    Cell Significance Index: 1.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0150
    Cell Significance Index: 23.0900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0124
    Cell Significance Index: 0.3300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0082
    Cell Significance Index: 1.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0072
    Cell Significance Index: 13.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0011
    Cell Significance Index: -0.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0159
    Cell Significance Index: -21.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0181
    Cell Significance Index: -13.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0207
    Cell Significance Index: -2.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0243
    Cell Significance Index: -0.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0283
    Cell Significance Index: -12.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0309
    Cell Significance Index: -1.6200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0400
    Cell Significance Index: -29.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0514
    Cell Significance Index: -38.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0784
    Cell Significance Index: -44.2200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0845
    Cell Significance Index: -52.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0981
    Cell Significance Index: -16.7500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0985
    Cell Significance Index: -3.4600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1336
    Cell Significance Index: -38.4500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1340
    Cell Significance Index: -7.5200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1556
    Cell Significance Index: -17.8300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1824
    Cell Significance Index: -26.5200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.1868
    Cell Significance Index: -1.4400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2105
    Cell Significance Index: -24.5300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2392
    Cell Significance Index: -50.3800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3226
    Cell Significance Index: -19.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3230
    Cell Significance Index: -8.0800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3372
    Cell Significance Index: -4.6000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3406
    Cell Significance Index: -5.7000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3755
    Cell Significance Index: -25.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4073
    Cell Significance Index: -25.6700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4089
    Cell Significance Index: -42.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4485
    Cell Significance Index: -19.8400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4617
    Cell Significance Index: -23.3300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4811
    Cell Significance Index: -10.0700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4835
    Cell Significance Index: -16.8000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4986
    Cell Significance Index: -13.3600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5257
    Cell Significance Index: -10.2600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5506
    Cell Significance Index: -28.6800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5548
    Cell Significance Index: -21.0100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6036
    Cell Significance Index: -15.4200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6096
    Cell Significance Index: -48.2800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6316
    Cell Significance Index: -38.7200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.7120
    Cell Significance Index: -20.9100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8133
    Cell Significance Index: -18.7900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.8176
    Cell Significance Index: -33.5000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8922
    Cell Significance Index: -28.5800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.9473
    Cell Significance Index: -24.3500
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.9916
    Cell Significance Index: -12.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **NF-kB Subunit:** The REL proto-oncogene encodes for the c-Rel protein, which is a subunit of the NF-kB transcription factor complex. 2. **Dimerization with other NF-kB subunits:** c-Rel can dimerize with other NF-kB subunits, such as p50 and p65, to form the NF-kB complex. 3. **Activation of NF-kB:** c-Rel can be activated by various stimuli, including cytokines, stress, and bacterial products, leading to the translocation of the NF-kB complex to the nucleus. 4. **Regulation of Gene Expression:** NF-kB, including the c-Rel subunit, regulates the expression of genes involved in immune responses, inflammation, and cellular stress. **Pathways and Functions:** 1. **Activation of NF-kB in B cells:** c-Rel plays a crucial role in the activation of NF-kB in B cells, which is essential for the regulation of class switching and antibody production. 2. **Adaptive immune system:** NF-kB, including the c-Rel subunit, is involved in the regulation of the adaptive immune system, including T cell activation and antibody production. 3. **Canonical NF-kB signal transduction:** c-Rel is a key component of the canonical NF-kB signaling pathway, which involves the activation of NF-kB by IKK and subsequent translocation to the nucleus. 4. **Non-canonical NF-kB signal transduction:** c-Rel is also involved in the non-canonical NF-kB signaling pathway, which is activated by the receptor-associated kinase (RANK) and the NF-κB-inducing kinase (NIK). **Clinical Significance:** 1. **Cancer:** Dysregulation of NF-kB, including the c-Rel subunit, has been implicated in various cancers, including lymphoma, leukemia, and solid tumors. 2. **Autoimmune disorders:** NF-kB, including the c-Rel subunit, is involved in the regulation of autoimmune disorders, such as rheumatoid arthritis and lupus. 3. **Inflammatory conditions:** NF-kB, including the c-Rel subunit, is involved in the regulation of inflammatory conditions, such as asthma and chronic obstructive pulmonary disease (COPD). 4. **Infectious diseases:** NF-kB, including the c-Rel subunit, is involved in the regulation of the innate immune response to infectious diseases, such as bacterial and viral infections. In conclusion, the REL proto-oncogene plays a critical role in the regulation of immune responses, cellular stress, and inflammation. Its dysregulation has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions. Further research is needed to fully understand the mechanisms of NF-kB regulation and its clinical significance.

Genular Protein ID: 921745193

Symbol: REL_HUMAN

Name: Proto-oncogene c-Rel

UniProtKB Accession Codes:

Q04864 Q17RU2 Q2PNZ7 Q6LDY0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 19 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2666912

Title: A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.

PubMed ID: 2666912

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3016517

Title: Genetic characterization of human c-rel sequences.

PubMed ID: 3016517

DOI: 10.1128/mcb.5.10.2826-2831.1985

PubMed ID: 1740106

Title: A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene.

PubMed ID: 1740106

DOI: 10.1002/j.1460-2075.1992.tb05043.x

PubMed ID: 8152812

Title: Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor.

PubMed ID: 8152812

PubMed ID: 9056676

Title: Regulation of intercellular adhesion molecule-1 gene by tumor necrosis factor-alpha is mediated by the nuclear factor-kappaB heterodimers p65/p65 and p65/c-Rel in the absence of p50.

PubMed ID: 9056676

PubMed ID: 9315679

Title: A new member of the IkappaB protein family, IkappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription.

PubMed ID: 9315679

DOI: 10.1128/mcb.17.10.6184

PubMed ID: 10823840

Title: Tumor necrosis factor-alpha activation of NF-kappa B requires the phosphorylation of Ser-471 in the transactivation domain of c-Rel.

PubMed ID: 10823840

DOI: 10.1074/jbc.m909396199

PubMed ID: 15102766

Title: Leishmania major amastigotes induce p50/c-Rel NF-kappa B transcription factor in human macrophages: involvement in cytokine synthesis.

PubMed ID: 15102766

DOI: 10.1128/iai.72.5.2582-2589.2004

PubMed ID: 15024091

Title: Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras.

PubMed ID: 15024091

DOI: 10.1128/mcb.24.7.3048-3056.2004

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 31103457

Title: Combined immunodeficiency in a patient with c-Rel deficiency.

PubMed ID: 31103457

DOI: 10.1016/j.jaci.2019.05.003

PubMed ID: 34623332

Title: Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents.

PubMed ID: 34623332

DOI: 10.1172/jci150143

Sequence Information:

  • Length: 619
  • Mass: 68520
  • Checksum: 03E1033BDF7B1B30
  • Sequence:
    • MASGAYNPYI EIIEQPRQRG MRFRYKCEGR SAGSIPGEHS TDNNRTYPSI QIMNYYGKGK 
VRITLVTKND PYKPHPHDLV GKDCRDGYYE AEFGQERRPL FFQNLGIRCV KKKEVKEAII 
TRIKAGINPF NVPEKQLNDI EDCDLNVVRL CFQVFLPDEH GNLTTALPPV VSNPIYDNRA 
PNTAELRICR VNKNCGSVRG GDEIFLLCDK VQKDDIEVRF VLNDWEAKGI FSQADVHRQV 
AIVFKTPPYC KAITEPVTVK MQLRRPSDQE VSESMDFRYL PDEKDTYGNK AKKQKTTLLF 
QKLCQDHVET GFRHVDQDGL ELLTSGDPPT LASQSAGITV NFPERPRPGL LGSIGEGRYF 
KKEPNLFSHD AVVREMPTGV SSQAESYYPS PGPISSGLSH HASMAPLPSS SWSSVAHPTP 
RSGNTNPLSS FSTRTLPSNS QGIPPFLRIP VGNDLNASNA CIYNNADDIV GMEASSMPSA 
DLYGISDPNM LSNCSVNMMT TSSDSMGETD NPRLLSMNLE NPSCNSVLDP RDLRQLHQMS 
SSSMSAGANS NTTVFVSQSD AFEGSDFSCA DNSMINESGP SNSTNPNSHG FVQDSQYSGI 
GSMQNEQLSD SFPYEFFQV

Genular Protein ID: 2467715084

Symbol: A0A8V8TPL7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8V8TPL7

Database IDs:

ARBA 4 CDD 2 CTD 1 EMBL 1 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 11 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 564
  • Mass: 62625
  • Checksum: 5307D1A4F7B0291F
  • Sequence:
    • MASGAYNPYI EIIEQPRQRG MRFRYKCEGR SAGSIPGEHS TDNNRTYPSI QIMNYYGKGK 
VRITLVTKND PYKPHPHDLV GKDCRDGYYE AEFGQERRPL FFQNLGIRCV KKKEVKEAII 
TRIKAGINPF NVPEKQLNDI EDCDLNVVRL CFQVFLPDEH GNLTTALPPV VSNPIYDNRA 
PNTAELRICR VNKNCGSVRG GDEIFLLCDK VQKDDIEVRF VLNDWEAKGI FSQADVHRQV 
AIVFKTPPYC KAITEPVTVK MQLRRPSDQE VSESMDFRYL PDEKDTYGNK AKKQKTTLLF 
QKLCQDHEPN LFSHDAVVRE MPTGVSSQAE SYYPSPGPIS SGLSHHASMA PLPSSSWSSV 
AHPTPRSGNT NPLSSFSTRT LPSNSQGIPP FLRIPVGNDL NASNACIYNN ADDIVGMEAS 
SMPSADLYGI SDPNMLSNCS VNMMTTSSDS MGETDNPRLL SMNLENPSCN SVLDPRDLRQ 
LHQMSSSSMS AGANSNTTVF VSQSDAFEGS DFSCADNSMI NESGPSNSTN PNSHGFVQDS 
QYSGIGSMQN EQLSDSFPYE FFQV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.