Details for: RPL10
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: embryonic stem cell (CL0002322)
Fold Change: 997.9667
Cell Significance Index: -411.1100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 813.0938
Cell Significance Index: -383.8800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 766.3711
Cell Significance Index: -394.2100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 574.9214
Cell Significance Index: -385.7900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 35.2986
Cell Significance Index: -94.5600 - Cell Name: pro-T cell (CL0000827)
Fold Change: 22.3841
Cell Significance Index: 571.8400 - Cell Name: abnormal cell (CL0001061)
Fold Change: 21.2801
Cell Significance Index: 2173.7600 - Cell Name: theca cell (CL0000503)
Fold Change: 18.6808
Cell Significance Index: 109.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 15.9501
Cell Significance Index: 749.6400 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 14.5510
Cell Significance Index: 186.3500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 14.4001
Cell Significance Index: 378.6500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 14.3745
Cell Significance Index: 384.5100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 13.2332
Cell Significance Index: 379.3400 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 13.0709
Cell Significance Index: 230.9800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 12.2970
Cell Significance Index: 427.3200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 12.1883
Cell Significance Index: 255.1200 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 12.0778
Cell Significance Index: 32.3600 - Cell Name: lactocyte (CL0002325)
Fold Change: 11.5744
Cell Significance Index: 1495.3400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 10.8763
Cell Significance Index: 123.5600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 10.1225
Cell Significance Index: 1390.1000 - Cell Name: peg cell (CL4033014)
Fold Change: 10.0293
Cell Significance Index: 231.7100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 10.0102
Cell Significance Index: 707.9600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 9.8498
Cell Significance Index: 1211.1200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 9.5027
Cell Significance Index: 175.6400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 9.4995
Cell Significance Index: 1712.4600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 9.4519
Cell Significance Index: 704.4400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 9.1257
Cell Significance Index: 4034.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 9.0911
Cell Significance Index: 1165.4200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 9.0472
Cell Significance Index: 4940.8900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 9.0412
Cell Significance Index: 1066.2300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 8.4654
Cell Significance Index: 248.6200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 8.3421
Cell Significance Index: 538.1900 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 8.0496
Cell Significance Index: 87.5100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 7.6846
Cell Significance Index: 5816.6100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 6.9163
Cell Significance Index: 363.1300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 5.6638
Cell Significance Index: 967.1300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 5.1394
Cell Significance Index: 139.8900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.8805
Cell Significance Index: 227.5500 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 4.1948
Cell Significance Index: 87.4900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 2.7741
Cell Significance Index: 219.7100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 2.7725
Cell Significance Index: 2032.7800 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 2.5556
Cell Significance Index: 15.7300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.4285
Cell Significance Index: 481.9400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 2.0379
Cell Significance Index: 1840.1100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.9646
Cell Significance Index: 194.3400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.8650
Cell Significance Index: 213.6700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.0740
Cell Significance Index: 204.3900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.2693
Cell Significance Index: 2.4800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.1528
Cell Significance Index: 4.0800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0827
Cell Significance Index: 16.5800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0411
Cell Significance Index: -77.4100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1612
Cell Significance Index: -119.4200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1633
Cell Significance Index: -301.2600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.1684
Cell Significance Index: -60.3900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1871
Cell Significance Index: -288.1000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.2748
Cell Significance Index: -373.7100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.3298
Cell Significance Index: -185.9800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.3674
Cell Significance Index: -229.4500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.4323
Cell Significance Index: -274.5300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.5658
Cell Significance Index: -31.7500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.7164
Cell Significance Index: -325.1400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.7766
Cell Significance Index: -163.5700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.9235
Cell Significance Index: -63.8700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -1.0432
Cell Significance Index: -119.0800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -1.1849
Cell Significance Index: -72.8300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.2026
Cell Significance Index: -62.4700 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.3238
Cell Significance Index: -22.8200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -1.7505
Cell Significance Index: -284.7100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -2.0202
Cell Significance Index: -91.5700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -2.2251
Cell Significance Index: -323.4500 - Cell Name: kidney cell (CL1000497)
Fold Change: -2.3521
Cell Significance Index: -18.7800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -2.5968
Cell Significance Index: -43.4600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -2.7316
Cell Significance Index: -87.4900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -3.4874
Cell Significance Index: -363.1200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -3.5794
Cell Significance Index: -225.6000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -4.0925
Cell Significance Index: -314.0600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -4.6826
Cell Significance Index: -281.1200 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -4.7155
Cell Significance Index: -40.5200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -4.9753
Cell Significance Index: -334.5400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -5.5683
Cell Significance Index: -341.3900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -5.7386
Cell Significance Index: -143.4500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -6.8468
Cell Significance Index: -149.9200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -6.9668
Cell Significance Index: -119.3900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -7.0919
Cell Significance Index: -84.5400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -7.2704
Cell Significance Index: -108.9400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -7.7001
Cell Significance Index: -226.8000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -8.1496
Cell Significance Index: -111.1900 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -8.9273
Cell Significance Index: -64.1200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -8.9789
Cell Significance Index: -329.6100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -8.9853
Cell Significance Index: -397.4400 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -9.0247
Cell Significance Index: -49.2100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -9.1777
Cell Significance Index: -55.4500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -10.1880
Cell Significance Index: -261.8800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -10.4309
Cell Significance Index: -107.9800 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -10.5381
Cell Significance Index: -135.7100 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -10.5491
Cell Significance Index: -88.6100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -10.5729
Cell Significance Index: -229.0600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -10.6133
Cell Significance Index: -401.9000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -10.7327
Cell Significance Index: -309.2300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -11.2123
Cell Significance Index: -367.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3019187403
Symbol: RL10_HUMAN
Name: Laminin receptor homolog
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1658743
Title: The isolation and characterization of a novel cDNA demonstrating an altered mRNA level in nontumorigenic Wilms' microcell hybrid cells.
PubMed ID: 1658743
PubMed ID: 1303197
Title: Identification and characterization of a new gene in the human Xq28 region.
PubMed ID: 1303197
DOI: 10.1093/hmg/1.4.269
PubMed ID: 1339145
Title: Genomic organization of a cDNA (QM) demonstrating an altered mRNA level in nontumorigenic Wilms' microcell hybrid cells and its localization to Xq28.
PubMed ID: 1339145
DOI: 10.1093/hmg/1.7.529
PubMed ID: 12138090
Title: QM, a putative tumor suppressor, regulates proto-oncogene c-Yes.
PubMed ID: 12138090
PubMed ID: 16627977
Title: Loss of heterozygosity and microsatellite instability at the Xq28 and the A/G heterozygosity of the QM gene are associated with ovarian cancer.
PubMed ID: 16627977
DOI: 10.4161/cbt.5.5.2610
PubMed ID: 8733135
Title: Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci.
PubMed ID: 8733135
DOI: 10.1093/hmg/5.5.659
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1534224
Title: cDNA cloning and genomic analysis of a new multigene family sharing common phylogenetic and expression profiles with the laminin receptor gene.
PubMed ID: 1534224
PubMed ID: 9582194
PubMed ID: 12962325
Title: Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing.
PubMed ID: 12962325
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24524803
Title: A new system for naming ribosomal proteins.
PubMed ID: 24524803
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 18258260
Title: Crystal structure of human ribosomal protein L10 core domain reveals eukaryote-specific motifs in addition to the conserved fold.
PubMed ID: 18258260
PubMed ID: 16940977
Title: Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autism.
PubMed ID: 16940977
PubMed ID: 21567917
Title: Mutation and expression analyses of the ribosomal protein gene RPL10 in an extended German sample of patients with autism spectrum disorder.
PubMed ID: 21567917
DOI: 10.1002/ajmg.a.33977
PubMed ID: 25316788
Title: A novel ribosomopathy caused by dysfunction of RPL10 disrupts neurodevelopment and causes X-linked microcephaly in humans.
PubMed ID: 25316788
PubMed ID: 25846674
Title: RPL10 mutation segregating in a family with X-linked syndromic Intellectual Disability.
PubMed ID: 25846674
DOI: 10.1002/ajmg.a.37094
PubMed ID: 26290468
Title: A novel mutation in RPL10 (Ribosomal Protein L10) causes X-Linked intellectual disability, cerebellar hypoplasia, and spondylo-epiphyseal dysplasia.
PubMed ID: 26290468
DOI: 10.1002/humu.22860
Sequence Information:
- Length: 214
- Mass: 24577
- Checksum: 0860CECC8BF674FE
- Sequence:
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDMVAEKRL IPDGCGVKYI PSRGPLDKWR ALHS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.