Details for: SGCA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 46.0316
Cell Significance Index: -7.1600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 28.3863
Cell Significance Index: -7.2000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 15.1961
Cell Significance Index: -6.2600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 11.7554
Cell Significance Index: -5.5500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 5.6848
Cell Significance Index: 163.7900 - Cell Name: myometrial cell (CL0002366)
Fold Change: 5.3929
Cell Significance Index: 62.1100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 4.8151
Cell Significance Index: 295.2100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 4.1947
Cell Significance Index: 87.0200 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 4.1384
Cell Significance Index: 44.9900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 3.4444
Cell Significance Index: 84.0400 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 2.8081
Cell Significance Index: 45.3100 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 2.7498
Cell Significance Index: 34.8300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 2.5772
Cell Significance Index: 55.8400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 2.0949
Cell Significance Index: 67.1000 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.8564
Cell Significance Index: 19.3800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.7518
Cell Significance Index: 79.4100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.2827
Cell Significance Index: 244.1100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 1.1878
Cell Significance Index: 17.9000 - Cell Name: perivascular cell (CL4033054)
Fold Change: 1.1251
Cell Significance Index: 5.2000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.9306
Cell Significance Index: 92.0600 - Cell Name: muscle precursor cell (CL0000680)
Fold Change: 0.9178
Cell Significance Index: 6.2700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7765
Cell Significance Index: 701.1300 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.6968
Cell Significance Index: 5.7600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.6182
Cell Significance Index: 15.8900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5670
Cell Significance Index: 12.0800 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 0.5075
Cell Significance Index: 2.9100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4922
Cell Significance Index: 80.0600 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.4816
Cell Significance Index: 7.6400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.4814
Cell Significance Index: 36.9500 - Cell Name: tongue muscle cell (CL0002673)
Fold Change: 0.4754
Cell Significance Index: 3.5600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4523
Cell Significance Index: 49.2000 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.3126
Cell Significance Index: 2.9900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2559
Cell Significance Index: 17.7000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2187
Cell Significance Index: 13.1300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.1876
Cell Significance Index: 2.7700 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0877
Cell Significance Index: 1.5500 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.0786
Cell Significance Index: 0.6600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0268
Cell Significance Index: 12.1700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0148
Cell Significance Index: 0.3700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0025
Cell Significance Index: 0.3200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0002
Cell Significance Index: -0.4400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0009
Cell Significance Index: -0.0300 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0020
Cell Significance Index: -0.0300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0043
Cell Significance Index: -8.0000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0050
Cell Significance Index: -7.7200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0059
Cell Significance Index: -8.0000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0067
Cell Significance Index: -4.2600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0092
Cell Significance Index: -6.9600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0105
Cell Significance Index: -7.7600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0125
Cell Significance Index: -7.0700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0159
Cell Significance Index: -0.8000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0175
Cell Significance Index: -6.2800 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.0187
Cell Significance Index: -0.1800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0190
Cell Significance Index: -2.7600 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0191
Cell Significance Index: -0.2500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0203
Cell Significance Index: -3.6600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0255
Cell Significance Index: -7.3300 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: -0.0262
Cell Significance Index: -0.0800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0282
Cell Significance Index: -3.2900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0290
Cell Significance Index: -1.1900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0305
Cell Significance Index: -6.0600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0311
Cell Significance Index: -0.6500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0325
Cell Significance Index: -6.5200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0340
Cell Significance Index: -4.1800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0392
Cell Significance Index: -6.7000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0416
Cell Significance Index: -8.7600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0459
Cell Significance Index: -4.7800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0477
Cell Significance Index: -5.6200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0521
Cell Significance Index: -7.1600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0543
Cell Significance Index: -7.0200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0558
Cell Significance Index: -1.5600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0565
Cell Significance Index: -5.7800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0664
Cell Significance Index: -7.6100 - Cell Name: embryonic fibroblast (CL2000042)
Fold Change: -0.0794
Cell Significance Index: -0.3800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0830
Cell Significance Index: -3.8700 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: -0.0914
Cell Significance Index: -0.8800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0934
Cell Significance Index: -6.9600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0958
Cell Significance Index: -6.1800 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0972
Cell Significance Index: -1.5600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1016
Cell Significance Index: -6.8300 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.1034
Cell Significance Index: -1.5700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1039
Cell Significance Index: -1.1800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1051
Cell Significance Index: -6.4600 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1170
Cell Significance Index: -1.8100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1239
Cell Significance Index: -6.9500 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.1263
Cell Significance Index: -1.6200 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: -0.1282
Cell Significance Index: -0.9600 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1328
Cell Significance Index: -0.9000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1386
Cell Significance Index: -6.5200 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.1431
Cell Significance Index: -1.9300 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1452
Cell Significance Index: -3.6200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1490
Cell Significance Index: -7.7400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1502
Cell Significance Index: -5.2200 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: -0.1648
Cell Significance Index: -1.6600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1665
Cell Significance Index: -8.7400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1721
Cell Significance Index: -2.8800 - Cell Name: muscle fibroblast (CL1001609)
Fold Change: -0.1747
Cell Significance Index: -1.0700 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: -0.1753
Cell Significance Index: -1.8500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1781
Cell Significance Index: -6.2400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1796
Cell Significance Index: -5.2900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2519417161
Symbol: SGCA_HUMAN
Name: Alpha-sarcoglycan
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8069911
Title: Missense mutations in the adhalin gene linked to autosomal recessive muscular dystrophy.
PubMed ID: 8069911
PubMed ID: 7937874
Title: Human adhalin is alternatively spliced and the gene is on chromosome 17q21.
PubMed ID: 7937874
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8528203
Title: A common missense mutation in the adhalin gene in three unrelated Brazilian families with a relatively mild form of autosomal recessive limb-girdle muscular dystrophy.
PubMed ID: 8528203
DOI: 10.1093/hmg/4.7.1163
PubMed ID: 7657792
Title: Adhalin gene mutations in patients with autosomal recessive childhood onset muscular dystrophy with adhalin deficiency.
PubMed ID: 7657792
DOI: 10.1172/jci118152
PubMed ID: 7663524
Title: Primary adhalinopathy: a common cause of autosomal recessive muscular dystrophy of variable severity.
PubMed ID: 7663524
DOI: 10.1038/ng0695-243
PubMed ID: 9192266
Title: Mutational diversity and hot spots in the alpha-sarcoglycan gene in autosomal recessive muscular dystrophy (LGMD2D).
PubMed ID: 9192266
DOI: 10.1136/jmg.34.6.470
PubMed ID: 9032047
Title: Mutations in the sarcoglycan genes in patients with myopathy.
PubMed ID: 9032047
PubMed ID: 9585331
Title: Homozygous alpha-sarcoglycan mutation in two siblings: one asymptomatic and one steroid-responsive mild limb-girdle muscular dystrophy patient.
PubMed ID: 9585331
DOI: 10.1002/(sici)1097-4598(199806)21:6<769::aid-mus9>3.0.co;2-5
PubMed ID: 30345904
Title: The impact of PYROXD1 deficiency on cellular respiration and correlations with genetic analyses of limb-girdle muscular dystrophy in Saudi Arabia and Sudan.
PubMed ID: 30345904
Sequence Information:
- Length: 387
- Mass: 42875
- Checksum: 9CD0270A00BE03E6
- Sequence:
MAETLFWTPL LVVLLAGLGD TEAQQTTLHP LVGRVFVHTL DHETFLSLPE HVAVPPAVHI TYHAHLQGHP DLPRWLRYTQ RSPHHPGFLY GSATPEDRGL QVIEVTAYNR DSFDTTRQRL VLEIGDPEGP LLPYQAEFLV RSHDAEEVLP STPASRFLSA LGGLWEPGEL QLLNVTSALD RGGRVPLPIE GRKEGVYIKV GSASPFSTCL KMVASPDSHA RCAQGQPPLL SCYDTLAPHF RVDWCNVTLV DKSVPEPADE VPTPGDGILE HDPFFCPPTE APDRDFLVDA LVTLLVPLLV ALLLTLLLAY VMCCRREGRL KRDLATSDIQ MVHHCTIHGN TEELRQMAAS REVPRPLSTL PMFNVHTGER LPPRVDSAQV PLILDQH
Genular Protein ID: 2855513227
Symbol: A0A0S2Z4P8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 263
- Mass: 29354
- Checksum: A5437E496658776B
- Sequence:
MAETLFWTPL LVVLLAGLGD TEAQQTTLHP LVGRVFVHTL DHETFLSLPE HVAVPPAVHI TYHAHLQGHP DLPRWLRYTQ RSPHHPGFLY GSATPEDRGL QVIEVTAYNR DSFDTTRQRL VLEIGDPEGP LLPYQAEFLV RSHDAEEVLP STPASRFLSA LGGLWEPGEL QLLNVTSALD RGGRVPLPIE GRKEGLKRDL ATSDIQMVHH CTIHGNTEEL RQMAASREVP RPLSTLPMFN VHTGERLPPR VDSAQVPLIL DQH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.