Details for: SMARCB1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: GABAergic neuron (CL0000617)
Fold Change: 2.55
Marker Score: 10621 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.37
Marker Score: 4944 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 2.34
Marker Score: 15210 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.32
Marker Score: 6891 - Cell Name: centroblast (CL0009112)
Fold Change: 2.29
Marker Score: 1128 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 2.26
Marker Score: 2714 - Cell Name: germinal center B cell (CL0000844)
Fold Change: 2.24
Marker Score: 1365 - Cell Name: neural cell (CL0002319)
Fold Change: 2.2
Marker Score: 1062.5 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 2.15
Marker Score: 2166 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.15
Marker Score: 28345 - Cell Name: Unknown (CL0002371)
Fold Change: 2.14
Marker Score: 2276 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2.13
Marker Score: 2392 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 2.13
Marker Score: 2003 - Cell Name: neural crest cell (CL0011012)
Fold Change: 2.11
Marker Score: 2255 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 2.11
Marker Score: 1325 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2.09
Marker Score: 3560 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 2.02
Marker Score: 1220 - Cell Name: pro-T cell (CL0000827)
Fold Change: 1.99
Marker Score: 8164.5 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.98
Marker Score: 5383 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.96
Marker Score: 19842.5 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.96
Marker Score: 1305 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.94
Marker Score: 4104 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.93
Marker Score: 5238 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 1.92
Marker Score: 1803 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 1.91
Marker Score: 677 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.9
Marker Score: 3852 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.87
Marker Score: 2650 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.86
Marker Score: 7212 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.82
Marker Score: 1927 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.81
Marker Score: 18218 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 1.78
Marker Score: 842 - Cell Name: memory B cell (CL0000787)
Fold Change: 1.76
Marker Score: 1328 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 1.75
Marker Score: 3049 - Cell Name: Leydig cell (CL0000178)
Fold Change: 1.75
Marker Score: 1884 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.74
Marker Score: 6830 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.73
Marker Score: 6402 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 1.72
Marker Score: 843 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.71
Marker Score: 2455.5 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.69
Marker Score: 2044 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.68
Marker Score: 565 - Cell Name: motor neuron (CL0000100)
Fold Change: 1.68
Marker Score: 995 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.67
Marker Score: 917.5 - Cell Name: plasmablast (CL0000980)
Fold Change: 1.66
Marker Score: 2204.5 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.65
Marker Score: 3891 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.65
Marker Score: 9788 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.64
Marker Score: 2052.5 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.63
Marker Score: 1534.5 - Cell Name: blood cell (CL0000081)
Fold Change: 1.61
Marker Score: 18772 - Cell Name: unswitched memory B cell (CL0000970)
Fold Change: 1.61
Marker Score: 946 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.6
Marker Score: 18070 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.6
Marker Score: 461 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 1.57
Marker Score: 828 - Cell Name: malignant cell (CL0001064)
Fold Change: 1.55
Marker Score: 20877 - Cell Name: preosteoblast (CL0007010)
Fold Change: 1.55
Marker Score: 439 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.54
Marker Score: 2519 - Cell Name: IgA plasma cell (CL0000987)
Fold Change: 1.53
Marker Score: 1303 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.51
Marker Score: 1488 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.49
Marker Score: 350 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 1.48
Marker Score: 1073 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.48
Marker Score: 1391 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 1.47
Marker Score: 472 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 1.46
Marker Score: 1727 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.46
Marker Score: 508 - Cell Name: naive B cell (CL0000788)
Fold Change: 1.44
Marker Score: 1287 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 1.44
Marker Score: 504 - Cell Name: enteric neuron (CL0007011)
Fold Change: 1.42
Marker Score: 757 - Cell Name: IgM plasma cell (CL0000986)
Fold Change: 1.42
Marker Score: 495 - Cell Name: centrocyte (CL0009111)
Fold Change: 1.41
Marker Score: 336 - Cell Name: immature B cell (CL0000816)
Fold Change: 1.41
Marker Score: 932.5 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.4
Marker Score: 8968 - Cell Name: stem cell (CL0000034)
Fold Change: 1.4
Marker Score: 3317 - Cell Name: oocyte (CL0000023)
Fold Change: 1.4
Marker Score: 345 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 1.39
Marker Score: 946 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 1.38
Marker Score: 709.5 - Cell Name: Unknown (CL0000548)
Fold Change: 1.37
Marker Score: 1000 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.37
Marker Score: 10211.5 - Cell Name: B-1b B cell (CL0000821)
Fold Change: 1.37
Marker Score: 315 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.37
Marker Score: 407 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.36
Marker Score: 47142 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.35
Marker Score: 5832 - Cell Name: glial cell (CL0000125)
Fold Change: 1.32
Marker Score: 1456 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.32
Marker Score: 1947.5 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.3
Marker Score: 1363 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.29
Marker Score: 3688.5 - Cell Name: pro-B cell (CL0000826)
Fold Change: 1.29
Marker Score: 1242.5 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 1.27
Marker Score: 440 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.27
Marker Score: 303 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 1.27
Marker Score: 439 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.25
Marker Score: 46238 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.24
Marker Score: 2339 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 1.23
Marker Score: 314 - Cell Name: osteoblast (CL0000062)
Fold Change: 1.23
Marker Score: 660 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 1.23
Marker Score: 501 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.23
Marker Score: 457 - Cell Name: stromal cell (CL0000499)
Fold Change: 1.22
Marker Score: 1432 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 1.22
Marker Score: 913 - Cell Name: neuron (CL0000540)
Fold Change: 1.22
Marker Score: 4952.5 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.21
Marker Score: 1082 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.21
Marker Score: 493 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.21
Marker Score: 45841.5
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Other Information
Genular Protein ID: 3351108447
Symbol: SNF5_HUMAN
Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7801128
Title: Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5.
PubMed ID: 7801128
PubMed ID: 9671307
Title: Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.
PubMed ID: 9671307
DOI: 10.1038/28212
PubMed ID: 10208879
Title: The mouse ortholog of the human SMARCB1 gene encodes two splice forms.
PubMed ID: 10208879
PubMed ID: 15461802
Title: A genome annotation-driven approach to cloning the human ORFeome.
PubMed ID: 15461802
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8895581
Title: Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
PubMed ID: 8895581
PubMed ID: 8709224
Title: Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1.
PubMed ID: 8709224
PubMed ID: 9448295
Title: Structure-function analysis of integrase interactor 1/hSNF5L1 reveals differential properties of two repeat motifs present in the highly conserved region.
PubMed ID: 9448295
PubMed ID: 10490642
Title: Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins.
PubMed ID: 10490642
PubMed ID: 10319872
Title: c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function.
PubMed ID: 10319872
DOI: 10.1038/8811
PubMed ID: 10365963
Title: Interaction of E1 and hSNF5 proteins stimulates replication of human papillomavirus DNA.
PubMed ID: 10365963
DOI: 10.1038/20966
PubMed ID: 10078207
Title: Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.
PubMed ID: 10078207
PubMed ID: 9892189
Title: Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors.
PubMed ID: 9892189
PubMed ID: 12016208
Title: The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity.
PubMed ID: 12016208
PubMed ID: 12226744
Title: A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle.
PubMed ID: 12226744
PubMed ID: 14604992
Title: P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells.
PubMed ID: 14604992
PubMed ID: 16267391
Title: Chromatin-remodeling factor INI1/hSNF5/BAF47 is involved in activation of the colony stimulating factor 1 promoter.
PubMed ID: 16267391
PubMed ID: 15899790
Title: SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas.
PubMed ID: 15899790
PubMed ID: 16959763
Title: Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.
PubMed ID: 16959763
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 20111005
Title: Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
PubMed ID: 20111005
DOI: 10.1038/emboj.2010.3
PubMed ID: 20460684
Title: Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.
PubMed ID: 20460684
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 16314535
Title: Human SWI/SNF generates abundant, structurally altered dinucleosomes on polynucleosomal templates.
PubMed ID: 16314535
PubMed ID: 18765789
Title: Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
PubMed ID: 18765789
DOI: 10.1101/gad.471408
PubMed ID: 17357086
Title: Germline mutation of INI1/SMARCB1 in familial schwannomatosis.
PubMed ID: 17357086
DOI: 10.1086/513207
PubMed ID: 18072270
Title: Evidence of a four-hit mechanism involving SMARCB1 and NF2 in schwannomatosis-associated schwannomas.
PubMed ID: 18072270
DOI: 10.1002/humu.20679
PubMed ID: 22368283
Title: Human PIH1 associates with histone H4 to mediate the glucose-dependent enhancement of pre-rRNA synthesis.
PubMed ID: 22368283
DOI: 10.1093/jmcb/mjs003
PubMed ID: 22952240
Title: SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions.
PubMed ID: 22952240
PubMed ID: 24874740
Title: The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesis.
PubMed ID: 24874740
PubMed ID: 26601204
Title: Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics.
PubMed ID: 26601204
PubMed ID: 23906836
Title: A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling.
PubMed ID: 23906836
DOI: 10.1093/hmg/ddt366
PubMed ID: 26073604
Title: The SWI/SNF subunit INI1 contains an N-terminal winged helix DNA binding domain that is a target for mutations in schwannomatosis.
PubMed ID: 26073604
PubMed ID: 22726846
Title: Disruption of an EHMT1-associated chromatin-modification module causes intellectual disability.
PubMed ID: 22726846
PubMed ID: 22426308
Title: Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.
PubMed ID: 22426308
DOI: 10.1038/ng.2219
Sequence Information:
- Length: 385
- Mass: 44141
- Checksum: B7BCA26875BD943D
- Sequence:
MMMMALSKTF GQKPVKFQLE DDGEFYMIGS EVGNYLRMFR GSLYKRYPSL WRRLATVEER KKIVASSHGK KTKPNTKDHG YTTLATSVTL LKASEVEEIL DGNDEKYKAV SISTEPPTYL REQKAKRNSQ WVPTLPNSSH HLDAVPCSTT INRNRMGRDK KRTFPLCFDD HDPAVIHENA SQPEVLVPIR LDMEIDGQKL RDAFTWNMNE KLMTPEMFSE ILCDDLDLNP LTFVPAIASA IRQQIESYPT DSILEDQSDQ RVIIKLNIHV GNISLVDQFE WDMSEKENSP EKFALKLCSE LGLGGEFVTT IAYSIRGQLS WHQKTYAFSE NPLPTVEIAI RNTGDADQWC PLLETLTDAE MEKKIRDQDR NTRRMRRLAN TAPAW
Genular Protein ID: 1996297471
Symbol: Q9H836_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 394
- Mass: 45051
- Checksum: D21D4C5325519D34
- Sequence:
MMMMALSKTF GQKPVKFQLE DDGEFYMIGS EVGNYLRMFR GSLYKRYPSL WRRLATVEER KKIVASSHDH GYTTLATSVT LLKASEVEEI LDGNDEKYKA VSISTEPPTY LREQKAKRNS QWVPTLPNSS HHLDAVPCST TINRDRMGRD KKRTFPLWCG CIAALTLRAD SALVLHFDDH DPAVIHENAS QPEVLVPIRL DMEIDGQKLR DAFTWNMNEK LMTPEMFSEI LCDDLDLNPL TFVPAIASAI RQQIESYPTD SILEDQSDQR VIIKLNIHVG NISLVDQFEW DMSEKENSPE KFALKLCSEL GLGGEFVTTI AYSIRGQLSW HQKTYAFSEN PLPTVEIAIR NTGDADQWCP LLETLTDAEM EKKIRDQDRN TRRMRRLANT APAW
Genular Protein ID: 3169730616
Symbol: G5E975_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10591208
PubMed ID: 11181995
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
Sequence Information:
- Length: 394
- Mass: 45050
- Checksum: D21FEE5325557D34
- Sequence:
MMMMALSKTF GQKPVKFQLE DDGEFYMIGS EVGNYLRMFR GSLYKRYPSL WRRLATVEER KKIVASSHDH GYTTLATSVT LLKASEVEEI LDGNDEKYKA VSISTEPPTY LREQKAKRNS QWVPTLPNSS HHLDAVPCST TINRNRMGRD KKRTFPLWCG CIAALTLRAD SALVLHFDDH DPAVIHENAS QPEVLVPIRL DMEIDGQKLR DAFTWNMNEK LMTPEMFSEI LCDDLDLNPL TFVPAIASAI RQQIESYPTD SILEDQSDQR VIIKLNIHVG NISLVDQFEW DMSEKENSPE KFALKLCSEL GLGGEFVTTI AYSIRGQLSW HQKTYAFSEN PLPTVEIAIR NTGDADQWCP LLETLTDAEM EKKIRDQDRN TRRMRRLANT APAW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.