Details for: SMARCE1

Gene ID: 6605

Symbol: SMARCE1

Ensembl ID: ENSG00000073584

Description: SWI/SNF related BAF chromatin remodeling complex subunit E1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 206.3066
    Cell Significance Index: -32.0900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 133.2185
    Cell Significance Index: -33.7900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 99.4058
    Cell Significance Index: -40.9500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.2467
    Cell Significance Index: -42.6100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 89.5923
    Cell Significance Index: -36.4000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 81.2037
    Cell Significance Index: -41.7700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.6701
    Cell Significance Index: -36.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 32.4180
    Cell Significance Index: -39.9700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.6248
    Cell Significance Index: -33.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.4940
    Cell Significance Index: -41.4100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.7608
    Cell Significance Index: -29.9800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.5014
    Cell Significance Index: 35.9400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 3.0087
    Cell Significance Index: 104.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.2679
    Cell Significance Index: 127.2700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.0846
    Cell Significance Index: 54.8200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.0752
    Cell Significance Index: 19.1100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.9187
    Cell Significance Index: 312.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.9088
    Cell Significance Index: 262.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.7107
    Cell Significance Index: 186.0800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.6430
    Cell Significance Index: 37.9600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.6346
    Cell Significance Index: 18.5700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6323
    Cell Significance Index: 200.7100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.6109
    Cell Significance Index: 290.3900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.4660
    Cell Significance Index: 18.7800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.3055
    Cell Significance Index: 68.0000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2006
    Cell Significance Index: 655.6700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7968
    Cell Significance Index: 159.8400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.7908
    Cell Significance Index: 41.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7365
    Cell Significance Index: 21.2200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7258
    Cell Significance Index: 93.0400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5946
    Cell Significance Index: 70.1200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5883
    Cell Significance Index: 58.2000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.5264
    Cell Significance Index: 15.4600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5248
    Cell Significance Index: 36.3000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5153
    Cell Significance Index: 33.2500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5103
    Cell Significance Index: 13.8900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4597
    Cell Significance Index: 203.2300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.4471
    Cell Significance Index: 6.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4305
    Cell Significance Index: 26.4600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4270
    Cell Significance Index: 9.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3692
    Cell Significance Index: 132.4300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3468
    Cell Significance Index: 15.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2796
    Cell Significance Index: 17.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2793
    Cell Significance Index: 13.0200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2570
    Cell Significance Index: 48.9000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2131
    Cell Significance Index: 6.1100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1868
    Cell Significance Index: 13.2100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1503
    Cell Significance Index: 3.1500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1289
    Cell Significance Index: 116.4000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1221
    Cell Significance Index: 7.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0618
    Cell Significance Index: 10.5600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0585
    Cell Significance Index: 3.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0474
    Cell Significance Index: 2.2300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0350
    Cell Significance Index: 2.6900
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.0323
    Cell Significance Index: 0.1900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0275
    Cell Significance Index: 0.4600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0240
    Cell Significance Index: 0.6400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0080
    Cell Significance Index: -5.0000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0081
    Cell Significance Index: -6.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0163
    Cell Significance Index: -30.7500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0179
    Cell Significance Index: -13.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0189
    Cell Significance Index: -13.8500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0210
    Cell Significance Index: -38.6800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0251
    Cell Significance Index: -38.6100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0309
    Cell Significance Index: -42.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0521
    Cell Significance Index: -5.3200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0524
    Cell Significance Index: -29.5400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0605
    Cell Significance Index: -38.4000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0812
    Cell Significance Index: -1.6900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0873
    Cell Significance Index: -18.3900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0900
    Cell Significance Index: -40.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1072
    Cell Significance Index: -30.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1107
    Cell Significance Index: -3.8900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1248
    Cell Significance Index: -16.1200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1309
    Cell Significance Index: -5.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1374
    Cell Significance Index: -16.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1695
    Cell Significance Index: -12.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1733
    Cell Significance Index: -19.8500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1837
    Cell Significance Index: -2.1900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1875
    Cell Significance Index: -5.0200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1914
    Cell Significance Index: -4.8900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1936
    Cell Significance Index: -6.2000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1995
    Cell Significance Index: -39.6000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2039
    Cell Significance Index: -3.9800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2136
    Cell Significance Index: -4.5500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2303
    Cell Significance Index: -8.7200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2549
    Cell Significance Index: -37.0500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2960
    Cell Significance Index: -7.4000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.3022
    Cell Significance Index: -4.5900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3093
    Cell Significance Index: -35.3100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3277
    Cell Significance Index: -7.8600
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.3306
    Cell Significance Index: -3.3400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3544
    Cell Significance Index: -9.5000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4053
    Cell Significance Index: -42.2000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.4292
    Cell Significance Index: -3.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4352
    Cell Significance Index: -22.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4562
    Cell Significance Index: -36.1400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4568
    Cell Significance Index: -2.7600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5072
    Cell Significance Index: -7.6000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5407
    Cell Significance Index: -15.9300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SMARCE1 is a 27-kDa protein that belongs to the SWI/SNF subfamily of chromatin remodeling complexes. Its structure consists of a C-terminal domain that interacts with the SWI/SNF complex and a N-terminal domain that binds to histone H3. SMARCE1 exhibits a unique enzymatic activity, which includes: 1. **Chromatin remodeling**: SMARCE1 participates in the ATP-dependent remodeling of chromatin structure, allowing for the regulation of gene expression. 2. **Histone modification**: SMARCE1 is involved in the methylation of histone arginine 3 (H3R3) and the trimethylation of histone arginine 17 (H3R17). 3. **Transcriptional regulation**: SMARCE1 modulates the expression of target genes by interacting with transcription factors, such as Runx1. **Pathways and Functions** SMARCE1 is involved in various cellular processes, including: 1. **Cell differentiation**: SMARCE1 regulates the expression of genes involved in cell differentiation, including myoblast differentiation and stem cell population maintenance. 2. **Gene expression (transcription)**: SMARCE1 modulates the expression of target genes by interacting with transcription factors and RNA polymerase II. 3. **DNA repair**: SMARCE1 is involved in the regulation of DNA repair pathways, including double-strand break repair and nucleotide-excision repair. 4. **Cell cycle regulation**: SMARCE1 regulates the cell cycle by controlling the expression of genes involved in the G0 to G1 transition and the G1/S transition of the mitotic cell cycle. **Clinical Significance** Dysregulation of SMARCE1 has been implicated in several human diseases, including: 1. **Cancer**: SMARCE1 loss is observed in various types of cancer, including breast, lung, and colon cancer. 2. **Neurodegenerative diseases**: SMARCE1 is involved in the regulation of gene expression in neurons, and its loss has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 3. **Immunological disorders**: SMARCE1 plays a crucial role in regulating immune cell function, and its loss has been implicated in autoimmune diseases, such as lupus and rheumatoid arthritis. In conclusion, SMARCE1 is a critical regulator of chromatin structure and gene expression, and its dysregulation has significant implications for human health. Further research is needed to fully understand the mechanisms by which SMARCE1 regulates chromatin and to develop therapeutic strategies for the treatment of diseases associated with SMARCE1 loss.

Genular Protein ID: 2112138246

Symbol: SMCE1_HUMAN

Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

UniProtKB Accession Codes:

Q969G3 B3KMC1 B4DFR4 C0IMW4 C0IMW5 C0IMW7 H7C3F6 O43539

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 31 DIP 2 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 15 EMDB 3 Ensembl 10 ExpressionAtlas 1 GO 33 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 4 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9435219

Title: Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes.

PubMed ID: 9435219

DOI: 10.1073/pnas.95.2.492

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12192000

Title: REST repression of neuronal genes requires components of the hSWI.SNF complex.

PubMed ID: 12192000

DOI: 10.1074/jbc.m205691200

PubMed ID: 12110891

Title: Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

PubMed ID: 12110891

DOI: 10.1038/nature00876

PubMed ID: 12145209

Title: Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes.

PubMed ID: 12145209

DOI: 10.1093/emboj/cdf412

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 12672490

Title: Recent advances in understanding chromatin remodeling by SWI/SNF complexes.

PubMed ID: 12672490

DOI: 10.1016/s0959-437x(03)00022-4

PubMed ID: 12917342

Title: BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.

PubMed ID: 12917342

DOI: 10.1128/mcb.23.17.6210-6220.2003

PubMed ID: 16051670

Title: hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes.

PubMed ID: 16051670

DOI: 10.1210/me.2005-0097

PubMed ID: 18765789

Title: Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

PubMed ID: 18765789

DOI: 10.1101/gad.471408

PubMed ID: 20829358

Title: Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex.

PubMed ID: 20829358

DOI: 10.1074/jbc.m110.173997

PubMed ID: 22952240

Title: SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions.

PubMed ID: 22952240

DOI: 10.1074/jbc.r111.309302

PubMed ID: 26601204

Title: Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics.

PubMed ID: 26601204

DOI: 10.1126/sciadv.1500447

PubMed ID: 22426308

Title: Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

PubMed ID: 22426308

DOI: 10.1038/ng.2219

PubMed ID: 23377182

Title: Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas.

PubMed ID: 23377182

DOI: 10.1038/ng.2552

PubMed ID: 23906836

Title: A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling.

PubMed ID: 23906836

DOI: 10.1093/hmg/ddt366

PubMed ID: 25249420

Title: Pediatric intracranial clear cell meningioma associated with a germline mutation of SMARCE1: a novel case.

PubMed ID: 25249420

DOI: 10.1007/s00381-014-2558-5

Sequence Information:

  • Length: 411
  • Mass: 46649
  • Checksum: 6F1C1B7917BAD506
  • Sequence:
    • MSKRPSYAPP PTPAPATQMP STPGFVGYNP YSHLAYNNYR LGGNPGTNSR VTASSGITIP 
KPPKPPDKPL MPYMRYSRKV WDQVKASNPD LKLWEIGKII GGMWRDLTDE EKQEYLNEYE 
AEKIEYNESM KAYHNSPAYL AYINAKSRAE AALEEESRQR QSRMEKGEPY MSIQPAEDPD 
DYDDGFSMKH TATARFQRNH RLISEILSES VVPDVRSVVT TARMQVLKRQ VQSLMVHQRK 
LEAELLQIEE RHQEKKRKFL ESTDSFNNEL KRLCGLKVEV DMEKIAAEIA QAEEQARKRQ 
EEREKEAAEQ AERSQSSIVP EEEQAANKGE EKKDDENIPM ETEETHLEET TESQQNGEEG 
TSTPEDKESG QEGVDSMAEE GTSDSNTGSE SNSATVEEPP TDPIPEDEKK E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.