Details for: SNRPF
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 356.6165
Cell Significance Index: -55.4700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 196.6027
Cell Significance Index: -80.9900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 187.8622
Cell Significance Index: -47.6500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 165.6137
Cell Significance Index: -78.1900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 144.8379
Cell Significance Index: -74.5000 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 116.7622
Cell Significance Index: -78.3500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 59.7345
Cell Significance Index: -73.6500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 24.1297
Cell Significance Index: -64.6400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 19.9744
Cell Significance Index: -78.8200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 12.4111
Cell Significance Index: -38.1200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.5672
Cell Significance Index: -18.7500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 5.6891
Cell Significance Index: 152.1800 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 5.2634
Cell Significance Index: 57.2200 - Cell Name: kidney cell (CL1000497)
Fold Change: 4.8633
Cell Significance Index: 38.8300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 4.5988
Cell Significance Index: 96.2600 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 3.4631
Cell Significance Index: 36.8000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 3.0924
Cell Significance Index: 218.7100 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.6745
Cell Significance Index: 70.3300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.6208
Cell Significance Index: 123.1800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.5317
Cell Significance Index: 298.5600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.5126
Cell Significance Index: 68.3900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 2.4888
Cell Significance Index: 1100.3500 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.4145
Cell Significance Index: 27.4300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.2462
Cell Significance Index: 78.0600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.2239
Cell Significance Index: 273.4500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.1584
Cell Significance Index: 1178.7300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.1479
Cell Significance Index: 294.9600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.0452
Cell Significance Index: 122.7800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.0164
Cell Significance Index: 363.4900 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.9473
Cell Significance Index: 251.5800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.8969
Cell Significance Index: 141.3800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.7737
Cell Significance Index: 114.4300 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 1.7514
Cell Significance Index: 15.0500 - Cell Name: sensory neuron (CL0000101)
Fold Change: 1.4901
Cell Significance Index: 8.4700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.4822
Cell Significance Index: 43.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.2877
Cell Significance Index: 60.0400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.2307
Cell Significance Index: 63.9300 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.2153
Cell Significance Index: 155.7900 - Cell Name: peg cell (CL4033014)
Fold Change: 1.1176
Cell Significance Index: 25.8200 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.0520
Cell Significance Index: 18.5900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.9639
Cell Significance Index: 27.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.9328
Cell Significance Index: 268.4100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.8015
Cell Significance Index: 36.3300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.7789
Cell Significance Index: 154.5700 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.7625
Cell Significance Index: 9.7700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.7368
Cell Significance Index: 6.7900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7366
Cell Significance Index: 665.0800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5124
Cell Significance Index: 11.1000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.4794
Cell Significance Index: 12.8000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3301
Cell Significance Index: 62.8200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.3243
Cell Significance Index: 245.4500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2941
Cell Significance Index: 105.4800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2795
Cell Significance Index: 56.0600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2466
Cell Significance Index: 40.1200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1439
Cell Significance Index: 4.6100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.1093
Cell Significance Index: 1.8300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0863
Cell Significance Index: 8.5400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0448
Cell Significance Index: 2.3500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0151
Cell Significance Index: 0.9500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0050
Cell Significance Index: 3.6600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0166
Cell Significance Index: -31.2100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0361
Cell Significance Index: -49.1000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0445
Cell Significance Index: -81.9800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0472
Cell Significance Index: -72.6300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0651
Cell Significance Index: -6.6500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0729
Cell Significance Index: -53.9700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0855
Cell Significance Index: -54.2900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1155
Cell Significance Index: -19.7200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1258
Cell Significance Index: -70.9200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1448
Cell Significance Index: -8.9000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1448
Cell Significance Index: -90.4200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1491
Cell Significance Index: -67.6500 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.1560
Cell Significance Index: -0.9600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1715
Cell Significance Index: -6.0300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1777
Cell Significance Index: -20.7100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2411
Cell Significance Index: -6.1600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2705
Cell Significance Index: -15.1800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3596
Cell Significance Index: -10.0500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.3672
Cell Significance Index: -9.1800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3711
Cell Significance Index: -5.5600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3793
Cell Significance Index: -43.4600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.4115
Cell Significance Index: -86.6800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.4288
Cell Significance Index: -62.3300 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.5389
Cell Significance Index: -9.9600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5883
Cell Significance Index: -12.5300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6346
Cell Significance Index: -50.2600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.7022
Cell Significance Index: -9.5800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.7454
Cell Significance Index: -77.6100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.8067
Cell Significance Index: -54.2400 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.8350
Cell Significance Index: -5.0500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.8731
Cell Significance Index: -60.3800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.8779
Cell Significance Index: -10.4700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.9274
Cell Significance Index: -71.1700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.0409
Cell Significance Index: -10.7800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.1034
Cell Significance Index: -67.6500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.3363
Cell Significance Index: -34.3500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.3451
Cell Significance Index: -39.6200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -1.3762
Cell Significance Index: -39.6500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.4532
Cell Significance Index: -64.2800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -1.5102
Cell Significance Index: -25.8800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1367816488
Symbol: RUXF_HUMAN
Name: Small nuclear ribonucleoprotein F
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7744013
Title: snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.
PubMed ID: 7744013
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11574479
Title: Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.
PubMed ID: 11574479
PubMed ID: 11991638
Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
PubMed ID: 11991638
PubMed ID: 12975319
Title: Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.
PubMed ID: 12975319
DOI: 10.1101/gad.274403
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 15146077
Title: The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.
PubMed ID: 15146077
DOI: 10.1261/rna.7320604
PubMed ID: 16314521
Title: Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs.
PubMed ID: 16314521
PubMed ID: 18984161
Title: An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.
PubMed ID: 18984161
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 19325628
Title: Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
PubMed ID: 19325628
DOI: 10.1038/nature07851
PubMed ID: 21816274
Title: Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly.
PubMed ID: 21816274
PubMed ID: 21516107
Title: Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis.
PubMed ID: 21516107
DOI: 10.1038/nature09956
PubMed ID: 23333303
Title: Structural basis of assembly chaperone-mediated snRNP formation.
PubMed ID: 23333303
PubMed ID: 25555158
Title: Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
PubMed ID: 25555158
DOI: 10.7554/elife.04986
PubMed ID: 26912367
Title: Molecular architecture of the human U4/U6.U5 tri-snRNP.
PubMed ID: 26912367
PubMed ID: 28502770
Title: An Atomic Structure of the Human Spliceosome.
PubMed ID: 28502770
PubMed ID: 28781166
Title: Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
PubMed ID: 28781166
PubMed ID: 28076346
Title: Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
PubMed ID: 28076346
DOI: 10.1038/nature21079
PubMed ID: 31799625
Title: Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly.
PubMed ID: 31799625
DOI: 10.1093/nar/gkz1135
PubMed ID: 32494006
Title: Molecular architecture of the human 17S U2 snRNP.
PubMed ID: 32494006
PubMed ID: 33509932
Title: Structure of the activated human minor spliceosome.
PubMed ID: 33509932
PubMed ID: 36797247
Title: Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
PubMed ID: 36797247
Sequence Information:
- Length: 86
- Mass: 9725
- Checksum: 416B88D575DAE58A
- Sequence:
MSLPLNPKPF LNGLTGKPVM VKLKWGMEYK GYLVSVDGYM NMQLANTEEY IDGALSGHLG EVLIRCNNVL YIRGVEEEEE DGEMRE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.