Details for: SSR3
Gene ID: 6747
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SSR3
Ensembl ID: ENSG00000114850
Description: signal sequence receptor subunit 3
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 112.13rCSI 88.21%PRS 8.99
-
CSI 82.5rCSI 84.46%PRS 14.29
-
CSI 74.63rCSI 64.62%PRS 8.38
-
CSI 69.77rCSI 86.31%PRS 6.6
-
CSI 69.42rCSI 90.98%PRS 37.41
-
CSI 63.93rCSI 61.54%PRS 7.79
-
CSI 60.11rCSI 72%PRS 13.13
-
CSI 57.37rCSI 76.25%PRS 8.18
-
CSI 55.73rCSI 45.06%PRS 7.42
-
CSI 50.19rCSI 35.05%PRS 7.93
-
CSI 48.6rCSI 50.8%PRS 7.92
-
CSI 43.39rCSI 42.68%PRS 8.17
-
CSI 43.18rCSI 62.27%PRS 10.51
-
CSI 38.32rCSI 34.61%PRS 6.65
-
CSI 37.19rCSI 53.59%PRS 12.17
-
CSI 37.02rCSI 32.86%PRS 7.52
-
CSI 36.23rCSI 34.94%PRS 4.73
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CSI 32.37rCSI 55.45%PRS 10.1
-
CSI 31.74rCSI 29.14%PRS 8.56
-
CSI 30.3rCSI 58.92%PRS 7.67
-
CSI 28.79rCSI 44.49%PRS 7.08
-
CSI 28.24rCSI 35.45%PRS 9.59
-
CSI 27.9rCSI 61.78%PRS 6.99
-
CSI 27.35rCSI 28.65%PRS 7
-
CSI 27.3rCSI 18.14%PRS 8.98
-
CSI 24.14rCSI 57.39%PRS 11.34
-
CSI 23.35rCSI 44.14%PRS 16.71
-
CSI 22.56rCSI 79.15%PRS 13.7
-
CSI 20.84rCSI 44.36%PRS 12.2
-
CSI 20.09rCSI 89.33%PRS 33.17
-
CSI 18.17rCSI 33.01%PRS 11.49
-
CSI 17.9rCSI 33.79%PRS 9.35
-
CSI 17.81rCSI 18.66%PRS 8.01
-
CSI 17.41rCSI 25.53%PRS 9.93
-
CSI 17.15rCSI 23.45%PRS 8.55
-
CSI 16.88rCSI 44.43%PRS 14.75
-
CSI 16.36rCSI 73.57%PRS 38.46
-
CSI 16.25rCSI 47.03%PRS 8.54
-
CSI 16.21rCSI 16.42%PRS 44.44
-
CSI 15.77rCSI 24.46%PRS 11.76
-
CSI 15.42rCSI 16.09%PRS 7.73
-
CSI 14.82rCSI 12.04%PRS 8.02
-
CSI 14.61rCSI 24.07%PRS 8.82
-
CSI 14.31rCSI 13.2%PRS 7.66
-
CSI 14.12rCSI 15%PRS 13.49
-
CSI 13.96rCSI 33.33%PRS 12.06
-
CSI 13.93rCSI 16.36%PRS 9.01
-
CSI 13.78rCSI 20.34%PRS 11.9
-
CSI 13.62rCSI 12.87%PRS 7.87
-
CSI 13.27rCSI 11.66%PRS 8.45
-
CSI 13.16rCSI 10.2%PRS 7.15
-
CSI 12.96rCSI 19.92%PRS 10.81
-
CSI 12.62rCSI 19.29%PRS 12.29
-
CSI 12.55rCSI 73.02%PRS 11.37
-
CSI 12.18rCSI 31.66%PRS 22.44
-
CSI 11.92rCSI 19.22%PRS 12.14
-
CSI 11.51rCSI 56.73%PRS 10.19
-
CSI 11.16rCSI 16.33%PRS 7.98
-
CSI 11.07rCSI 17.01%PRS 8.78
-
CSI 10.65rCSI 29.26%PRS 12.5
-
CSI 10.48rCSI 8.07%PRS 6.82
-
CSI 9.56rCSI 7.98%PRS 23.81
-
CSI 9.47rCSI 50.96%PRS 13.68
-
CSI 9.34rCSI 49.83%PRS 27.78
-
CSI 9.26rCSI 14.7%PRS 9.76
-
CSI 9.2rCSI 17.56%PRS 18.19
-
CSI 8.82rCSI 23.77%PRS 9.75
-
CSI 8.41rCSI 5.85%PRS 10.87
-
CSI 8.33rCSI 9.54%PRS 15.64
-
CSI 8.29rCSI 35.8%PRS 14.63
-
CSI 8.25rCSI 6.84%PRS 7.14
-
CSI 8.08rCSI 12.86%PRS 6.63
-
CSI 8.07rCSI 9.94%PRS 25.19
-
CSI 7.99rCSI 52.45%PRS 19.95
-
CSI 7.93rCSI 9.52%PRS 7.45
-
CSI 7.84rCSI 48.38%PRS 24.91
-
CSI 7.61rCSI 5.79%PRS 9.98
-
CSI 7.52rCSI 10.66%PRS 7.13
-
CSI 7.44rCSI 29.74%PRS 16.64
-
CSI 7rCSI 7.88%PRS 12.36
-
CSI 6.84rCSI 19.7%PRS 15.09
-
CSI 6.72rCSI 9.15%PRS 18.76
-
CSI 6.7rCSI 5.01%PRS 12.34
-
CSI 6.67rCSI 5.59%PRS 9.01
-
CSI 6.58rCSI 10.05%PRS 13.21
-
CSI 6.52rCSI 15.64%PRS 14.02
-
CSI 6.51rCSI 35.14%PRS 14.49
-
CSI 6.48rCSI 5.12%PRS 5.19
-
CSI 6.41rCSI 7.75%PRS 8.86
-
CSI 6.41rCSI 33.09%PRS 15.13
-
CSI 6.37rCSI 9.73%PRS 9.48
-
CSI 6.34rCSI 62.41%PRS 23.36
-
CSI 6.34rCSI 5.58%PRS 5.45
-
CSI 6.33rCSI 4.26%PRS 9.08
-
CSI 6.21rCSI 67.58%PRS 14.44
-
CSI 6.21rCSI 8.6%PRS 10.84
-
CSI 6.12rCSI 8.96%PRS 8.83
-
CSI 6.1rCSI 28.17%PRS 16.2
-
CSI 6.02rCSI 8.59%PRS 8.51
-
CSI 5.89rCSI 25.85%PRS 14.17
-
CSI -8.6rCSI -27.8%PRS 9.2%
-
CSI -8.4rCSI -20.0%PRS 9.9%
-
CSI -7.2rCSI -22.4%PRS 5.1%
-
CSI -5.6rCSI -9.5%PRS 16.1%
-
CSI -4.6rCSI -9.3%PRS 5.6%
-
CSI -3.9rCSI -10.4%PRS 9.0%
-
CSI -3.6rCSI -5.8%PRS 4.9%
-
CSI -3.6rCSI -22.4%PRS 6.1%
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CSI -3.3rCSI -6.6%PRS 21.1%
-
CSI -2.8rCSI -6.4%PRS 4.7%
-
CSI -1.5rCSI -4.4%PRS 28.3%
-
CSI -1.3rCSI -2.3%PRS 5.7%
-
CSI -1.2rCSI -2.1%PRS 10.0%
-
CSI -1.2rCSI -5.4%PRS 20.7%
-
CSI -0.9rCSI -1.0%PRS 13.2%
-
CSI -0.5rCSI -0.9%PRS 9.1%
-
CSI -0.2rCSI -0.7%PRS 22.6%
-
CSI 0.1rCSI 1.6%PRS 39.3%
-
CSI 0.1rCSI 0.7%PRS 11.4%
-
CSI 0.1rCSI 0.7%PRS 26.4%
-
CSI 0.2rCSI 0.1%PRS 9.3%
-
CSI 0.2rCSI 0.4%PRS 4.3%
-
CSI 0.2rCSI 1.9%PRS 30.8%
-
CSI 0.2rCSI 0.3%PRS 7.1%
-
CSI 0.2rCSI 1.9%PRS 22.5%
-
CSI 0.2rCSI 3.1%PRS 44.4%
-
CSI 0.2rCSI 3.8%PRS 54.2%
-
CSI 0.2rCSI 1.6%PRS 17.2%
-
CSI 0.2rCSI 0.6%PRS 5.8%
-
CSI 0.2rCSI 0.4%PRS 5.8%
-
CSI 0.2rCSI 0.7%PRS 4.7%
-
CSI 0.2rCSI 0.3%PRS 4.7%
-
CSI 0.2rCSI 6.2%PRS 39.2%
-
CSI 0.2rCSI 0.3%PRS 12.8%
-
CSI 0.2rCSI 2.0%PRS 8.0%
-
CSI 0.3rCSI 1.3%PRS 10.9%
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CSI 0.3rCSI 0.5%PRS 4.4%
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CSI 0.3rCSI 7.9%PRS 40.5%
-
CSI 0.3rCSI 2.1%PRS 25.6%
-
CSI 0.3rCSI 1.2%PRS 13.0%
-
CSI 0.3rCSI 0.7%PRS 16.2%
-
CSI 0.4rCSI 0.7%PRS 12.8%
-
CSI 0.4rCSI 1.0%PRS 14.1%
-
CSI 0.4rCSI 2.9%PRS 24.0%
-
CSI 0.5rCSI 11.7%PRS 26.1%
-
CSI 0.5rCSI 1.1%PRS 15.3%
-
CSI 0.5rCSI 0.8%PRS 10.9%
-
CSI 0.6rCSI 9.5%PRS 31.5%
-
CSI 0.6rCSI 1.4%PRS 24.3%
-
CSI 0.6rCSI 4.5%PRS 33.0%
-
CSI 0.6rCSI 0.9%PRS 8.2%
-
CSI 0.6rCSI 2.3%PRS 16.1%
-
CSI 0.6rCSI 2.1%PRS 12.4%
-
CSI 0.6rCSI 1.2%PRS 8.2%
-
CSI 0.7rCSI 2.6%PRS 11.7%
-
CSI 0.7rCSI 2.2%PRS 10.4%
-
CSI 0.7rCSI 1.5%PRS 5.4%
-
CSI 0.7rCSI 1.9%PRS 7.7%
-
CSI 0.7rCSI 7.0%PRS 29.4%
-
CSI 0.7rCSI 18.3%PRS 57.9%
-
CSI 0.8rCSI 4.2%PRS 25.8%
-
CSI 0.8rCSI 0.8%PRS 8.7%
-
CSI 0.8rCSI 3.6%PRS 18.5%
-
CSI 0.8rCSI 1.0%PRS 8.7%
-
CSI 0.8rCSI 0.6%PRS 12.7%
-
CSI 0.8rCSI 1.5%PRS 5.6%
-
CSI 0.8rCSI 2.9%PRS 24.3%
-
CSI 0.9rCSI 1.0%PRS 5.5%
-
CSI 0.9rCSI 1.6%PRS 14.9%
-
CSI 0.9rCSI 0.7%PRS 13.3%
-
CSI 0.9rCSI 2.3%PRS 9.4%
-
CSI 0.9rCSI 4.3%PRS 18.7%
-
CSI 0.9rCSI 22.4%PRS 27.7%
-
CSI 1.0rCSI 0.6%PRS 10.5%
-
CSI 1.0rCSI 2.5%PRS 7.0%
-
CSI 1.0rCSI 2.1%PRS 10.2%
-
CSI 1.0rCSI 0.7%PRS 11.3%
-
CSI 1.0rCSI 2.2%PRS 7.9%
-
CSI 1.0rCSI 6.0%PRS 35.1%
-
CSI 1.0rCSI 10.9%PRS 33.5%
-
CSI 1.0rCSI 2.9%PRS 10.9%
-
CSI 1.1rCSI 1.5%PRS 10.4%
-
CSI 1.1rCSI 7.2%PRS 49.6%
-
CSI 1.1rCSI 2.0%PRS 6.6%
-
CSI 1.2rCSI 3.4%PRS 12.1%
-
CSI 1.2rCSI 1.2%PRS 12.0%
-
CSI 1.2rCSI 5.6%PRS 28.0%
-
CSI 1.2rCSI 9.0%PRS 21.1%
-
CSI 1.2rCSI 2.4%PRS 17.2%
-
CSI 1.3rCSI 19.3%PRS 19.1%
-
CSI 1.3rCSI 1.6%PRS 8.0%
-
CSI 1.3rCSI 3.2%PRS 7.7%
-
CSI 1.3rCSI 1.7%PRS 10.6%
-
CSI 1.3rCSI 3.2%PRS 11.9%
-
CSI 1.3rCSI 2.2%PRS 5.9%
-
CSI 1.4rCSI 2.3%PRS 15.5%
-
CSI 1.4rCSI 1.9%PRS 6.8%
-
CSI 1.4rCSI 3.4%PRS 7.7%
-
CSI 1.4rCSI 4.9%PRS 32.0%
-
CSI 1.5rCSI 1.8%PRS 9.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 3431163339
Symbol: SSRG_HUMAN
Name: Translocon-associated protein subunit gamma
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25732826
Title: An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity.
PubMed ID: 25732826
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 185
- Mass: 21080
- Checksum: DEE0B14BF524F62A
- Sequence:
MAPKGSSKQQ SEEDLLLQDF SRNLSAKSSA LFFGNAFIVS AIPIWLYWRI WHMDLIQSAV LYSVMTLVST YLVAFAYKNV KFVLKHKVAQ KREDAVSKEV TRKLSEADNR KMSRKEKDER ILWKKNEVAD YEATTFSIFY NNTLFLVVVI VASFFILKNF NPTVNYILSI SASSGLIALL STGSK
Genular Protein ID: 3084284176
Symbol: C9J365_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 133
- Mass: 15113
- Checksum: B053A7EEF645D1A4
- Sequence:
MDLIQSAVLY SVMTLVSTYL VAFAYKNVKF VLKHKVAQKR EDAVSKEVTR KLSEADNRKM SRKEKDERIL WKKNEVADYE ATTFSIFYNN TLFLVVVIVA SFFILKNFNP TVNYILSISA SSGLIALLST GSK