Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 169.5970
Cell Significance Index: -26.3800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 92.8075
Cell Significance Index: -23.5400 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 71.4654
Cell Significance Index: -29.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 63.9496
Cell Significance Index: -25.9800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 61.8907
Cell Significance Index: -29.2200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 55.9697
Cell Significance Index: -28.7900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 22.2311
Cell Significance Index: -27.4100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 8.3804
Cell Significance Index: -22.4500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.2506
Cell Significance Index: -22.2700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.1616
Cell Significance Index: -28.2600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.0665
Cell Significance Index: -8.9000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.8336
Cell Significance Index: 52.5600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.5388
Cell Significance Index: 21.0000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.3931
Cell Significance Index: 137.8100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.7558
Cell Significance Index: 52.2700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.7370
Cell Significance Index: 20.0600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7138
Cell Significance Index: 37.0800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.6346
Cell Significance Index: 29.8300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6124
Cell Significance Index: 75.3000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5585
Cell Significance Index: 25.3200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5520
Cell Significance Index: 11.9600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5341
Cell Significance Index: 96.2900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4750
Cell Significance Index: 13.6900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4627
Cell Significance Index: 204.5600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.4626
Cell Significance Index: 63.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4448
Cell Significance Index: 20.7400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3994
Cell Significance Index: 25.7700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3985
Cell Significance Index: 217.6200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.3617
Cell Significance Index: 9.5100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.3265
Cell Significance Index: 6.0400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.3050
Cell Significance Index: 21.5700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2974
Cell Significance Index: 8.3100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2721
Cell Significance Index: 245.6800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1962
Cell Significance Index: 39.3600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1922
Cell Significance Index: 24.6400 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1821
Cell Significance Index: 23.5300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1740
Cell Significance Index: 34.5400 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.1698
Cell Significance Index: 3.0000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.1522
Cell Significance Index: 2.2800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.1363
Cell Significance Index: 3.6400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1257
Cell Significance Index: 9.3700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0975
Cell Significance Index: 18.5500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0768
Cell Significance Index: 2.7000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.0728
Cell Significance Index: 0.6700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0541
Cell Significance Index: 1.4500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0531
Cell Significance Index: 36.7500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0496
Cell Significance Index: 1.5900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.0443
Cell Significance Index: 1.3000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0413
Cell Significance Index: 0.8800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0277
Cell Significance Index: 3.2700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0274
Cell Significance Index: 9.8300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.0238
Cell Significance Index: 0.2700 - Cell Name: peg cell (CL4033014)
Fold Change: 0.0151
Cell Significance Index: 0.3500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0080
Cell Significance Index: 15.1000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0075
Cell Significance Index: -1.2800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0098
Cell Significance Index: -7.4500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0106
Cell Significance Index: -1.0800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0114
Cell Significance Index: -20.9900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0125
Cell Significance Index: -9.2000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0133
Cell Significance Index: -20.5200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0160
Cell Significance Index: -21.7700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0223
Cell Significance Index: -14.1900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0296
Cell Significance Index: -4.8200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0326
Cell Significance Index: -0.8200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0342
Cell Significance Index: -25.3600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0380
Cell Significance Index: -5.5200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0479
Cell Significance Index: -27.0400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0487
Cell Significance Index: -22.1300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0518
Cell Significance Index: -32.3700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0759
Cell Significance Index: -3.9600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0824
Cell Significance Index: -23.7000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1203
Cell Significance Index: -13.7900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1341
Cell Significance Index: -2.2500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1394
Cell Significance Index: -3.7300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1418
Cell Significance Index: -16.5200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1548
Cell Significance Index: -32.6000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1737
Cell Significance Index: -9.1200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1742
Cell Significance Index: -13.3700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2011
Cell Significance Index: -10.1600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2587
Cell Significance Index: -5.0500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2642
Cell Significance Index: -16.2400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2654
Cell Significance Index: -27.6300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2717
Cell Significance Index: -6.9400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2731
Cell Significance Index: -17.2100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2859
Cell Significance Index: -22.6400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3221
Cell Significance Index: -21.6600 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -0.3578
Cell Significance Index: -2.5700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3742
Cell Significance Index: -22.9400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.4788
Cell Significance Index: -26.8700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4803
Cell Significance Index: -16.6900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.4811
Cell Significance Index: -4.9800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.4897
Cell Significance Index: -10.2500 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.5226
Cell Significance Index: -21.4100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5272
Cell Significance Index: -23.3200 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.5356
Cell Significance Index: -15.7800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6380
Cell Significance Index: -24.1600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.6652
Cell Significance Index: -24.4200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.6866
Cell Significance Index: -17.6500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.6879
Cell Significance Index: -24.1000 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.6947
Cell Significance Index: -16.9500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3044278225
Symbol: STX4_HUMAN
Name: Syntaxin-4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8206394
Title: Isolation and sequence analysis of the human syntaxin-encoding gene.
PubMed ID: 8206394
PubMed ID: 8760387
Title: Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.
PubMed ID: 8760387
DOI: 10.1042/bj3170945
PubMed ID: 10080545
Title: Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1.
PubMed ID: 10080545
DOI: 10.1002/jlb.65.3.397
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10508479
Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.
PubMed ID: 10508479
DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 36355422
Title: Syntaxin 4 is essential for hearing in human and zebrafish.
PubMed ID: 36355422
DOI: 10.1093/hmg/ddac257
Sequence Information:
- Length: 297
- Mass: 34180
- Checksum: 5084FD1C49A86BAA
- Sequence:
MRDRTHELRQ GDDSSDEEDK ERVALVVHPG TARLGSPDEE FFHKVRTIRQ TIVKLGNKVQ ELEKQQVTIL ATPLPEESMK QELQNLRDEI KQLGREIRLQ LKAIEPQKEE ADENYNSVNT RMRKTQHGVL SQQFVELINK CNSMQSEYRE KNVERIRRQL KITNAGMVSD EELEQMLDSG QSEVFVSNIL KDTQVTRQAL NEISARHSEI QQLERSIREL HDIFTFLATE VEMQGEMINR IEKNILSSAD YVERGQEHVK TALENQKKAR KKKVLIAICV SITVVLLAVI IGVTVVG
Genular Protein ID: 1213771306
Symbol: B7Z425_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 219
- Mass: 25262
- Checksum: 4062706AB6A41D45
- Sequence:
MKQELQNLRD EIKQLGREIR LQLKAIEPQK EEADENYNSV NTRMRKTQHG VLSQQFVELI NKCNSMQSEY REKNVERIRR QLKITNAGMV SDEELEQMLD SGQSEVFVSN ILKDTQVTRQ ALNEISARHS EIQQLERSIR ELHDIFTFLA TEVEMQGEMI NRIEKNILSS ADYVERGQEH VKTALENQKK ARKKKVLIAI CVSITVVLLA VIIGVTVVG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.