Details for: SURF4

Gene ID: 6836

Symbol: SURF4

Ensembl ID: ENSG00000148248

Description: surfeit 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 293.5481
    Cell Significance Index: -45.6600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 181.8695
    Cell Significance Index: -46.1300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 119.5452
    Cell Significance Index: -56.4400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 118.1157
    Cell Significance Index: -48.6600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 114.2134
    Cell Significance Index: -46.4000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 104.4742
    Cell Significance Index: -53.7400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 84.2372
    Cell Significance Index: -56.5300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 49.3222
    Cell Significance Index: -47.0900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 40.0258
    Cell Significance Index: -49.3500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.3158
    Cell Significance Index: -38.3500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.6962
    Cell Significance Index: -50.1000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.0860
    Cell Significance Index: -34.0500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.0789
    Cell Significance Index: 124.8100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.0412
    Cell Significance Index: 95.1700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.0097
    Cell Significance Index: 218.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.7227
    Cell Significance Index: 46.8900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.5869
    Cell Significance Index: 45.4900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5421
    Cell Significance Index: 306.0400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.3467
    Cell Significance Index: 39.5500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.2460
    Cell Significance Index: 64.9000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.1982
    Cell Significance Index: 25.0800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.1372
    Cell Significance Index: 16.7900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.1067
    Cell Significance Index: 29.5500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0103
    Cell Significance Index: 202.6700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9463
    Cell Significance Index: 129.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.9402
    Cell Significance Index: 44.1900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7978
    Cell Significance Index: 143.8200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7454
    Cell Significance Index: 91.6500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7039
    Cell Significance Index: 20.2800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6679
    Cell Significance Index: 49.7800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6470
    Cell Significance Index: 353.3400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6211
    Cell Significance Index: 42.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.5443
    Cell Significance Index: 92.9500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.5344
    Cell Significance Index: 18.5700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5121
    Cell Significance Index: 66.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5111
    Cell Significance Index: 65.5200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4473
    Cell Significance Index: 9.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4317
    Cell Significance Index: 190.8500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4016
    Cell Significance Index: 20.8600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2571
    Cell Significance Index: 48.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2570
    Cell Significance Index: 92.1700
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.2503
    Cell Significance Index: 1.5600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2015
    Cell Significance Index: 5.6300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1763
    Cell Significance Index: 12.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0990
    Cell Significance Index: 74.9700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0988
    Cell Significance Index: 68.3600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0741
    Cell Significance Index: 7.3300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0710
    Cell Significance Index: 3.2200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0653
    Cell Significance Index: 58.9500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0185
    Cell Significance Index: 0.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0149
    Cell Significance Index: 1.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0043
    Cell Significance Index: 0.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0036
    Cell Significance Index: 6.8000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0026
    Cell Significance Index: 0.0600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0004
    Cell Significance Index: 0.2300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0077
    Cell Significance Index: -0.4900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0094
    Cell Significance Index: -14.4700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0109
    Cell Significance Index: -20.0800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0135
    Cell Significance Index: -9.9200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0139
    Cell Significance Index: -0.7000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0174
    Cell Significance Index: -12.9000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0223
    Cell Significance Index: -30.3700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0399
    Cell Significance Index: -24.9000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0538
    Cell Significance Index: -24.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0538
    Cell Significance Index: -5.5000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0546
    Cell Significance Index: -0.6200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0609
    Cell Significance Index: -34.3300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0846
    Cell Significance Index: -9.7000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1279
    Cell Significance Index: -26.9400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1286
    Cell Significance Index: -4.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1346
    Cell Significance Index: -4.7300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1610
    Cell Significance Index: -18.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1841
    Cell Significance Index: -52.9800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1852
    Cell Significance Index: -4.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2018
    Cell Significance Index: -29.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2336
    Cell Significance Index: -14.7200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2447
    Cell Significance Index: -18.7800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2929
    Cell Significance Index: -15.3800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3020
    Cell Significance Index: -35.1900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4517
    Cell Significance Index: -25.3500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4752
    Cell Significance Index: -49.4800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4861
    Cell Significance Index: -19.9200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5436
    Cell Significance Index: -10.6100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.5716
    Cell Significance Index: -7.3200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5850
    Cell Significance Index: -4.7700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5966
    Cell Significance Index: -8.1400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6002
    Cell Significance Index: -26.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6061
    Cell Significance Index: -37.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6183
    Cell Significance Index: -48.9700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6487
    Cell Significance Index: -6.7200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6549
    Cell Significance Index: -16.7300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.7266
    Cell Significance Index: -4.3900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7677
    Cell Significance Index: -29.0700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7808
    Cell Significance Index: -20.0700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.8177
    Cell Significance Index: -8.8900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.8224
    Cell Significance Index: -15.2000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.8295
    Cell Significance Index: -5.6200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.8742
    Cell Significance Index: -8.0500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.9172
    Cell Significance Index: -32.1300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9231
    Cell Significance Index: -29.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SURF4 is a gene with a relatively high degree of conservation across species, suggesting its importance in maintaining cellular homeostasis. Its expression is predominantly observed in cells involved in immune response, such as neutrophils, dendritic cells, and natural killer cells, highlighting its role in regulating immune system function. Furthermore, SURF4 is co-expressed with other genes involved in lipid metabolism and membrane trafficking, underscoring its potential involvement in these processes. **Pathways and Functions:** SURF4 is implicated in various cellular pathways, including: 1. **Immune System:** SURF4 is essential for the proper functioning of immune cells, such as neutrophils and natural killer cells, regulating their activation, proliferation, and survival. It also modulates the activity of immune checkpoint molecules, like B7-1 and B7-2, which are critical for maintaining immune homeostasis. 2. **Lipid Homeostasis:** SURF4 is involved in regulating lipid metabolism, particularly in the context of lipid trafficking and transport. It interacts with proteins involved in lipid synthesis and degradation, influencing the cellular lipid profile. 3. **Membrane Trafficking:** SURF4 plays a crucial role in regulating membrane trafficking, including endocytosis, exocytosis, and retrograde transport. It interacts with proteins involved in these processes, ensuring the proper functioning of cellular membranes. **Clinical Significance:** The dysregulation of SURF4 has been implicated in various diseases, including: 1. **Autoimmune Disorders:** Alterations in SURF4 expression have been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where immune system dysfunction plays a key role. 2. **Cancer:** SURF4 has been implicated in cancer progression, where its dysregulation contributes to enhanced cell proliferation, survival, and metastasis. 3. **Neurological Disorders:** SURF4 has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease, where its dysregulation contributes to impaired lipid metabolism and membrane trafficking. In conclusion, the SURF4 gene is a complex and multifaceted molecule with far-reaching implications in immune response, lipid homeostasis, and membrane trafficking. Further research is necessary to fully elucidate its mechanisms of action and to explore its potential as a therapeutic target in various diseases.

Genular Protein ID: 647388776

Symbol: SURF4_HUMAN

Name: N/A

UniProtKB Accession Codes:

O15260 B7Z6A4 O60923 Q5T8U6 Q9UNZ0 Q9UNZ1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CORUM 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 6 ExpressionAtlas 1 GO 23 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 STRING 1 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7540914

Title: The surf-4 gene encodes a novel 30 kDa integral membrane protein.

PubMed ID: 7540914

DOI: 10.3109/09687689509027508

PubMed ID: 9740673

Title: The human Surfeit locus.

PubMed ID: 9740673

DOI: 10.1006/geno.1998.5372

PubMed ID: 15308636

Title: Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

PubMed ID: 15308636

DOI: 10.1074/jbc.m406644200

PubMed ID: 18287528

Title: The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi.

PubMed ID: 18287528

DOI: 10.1091/mbc.e07-10-0989

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30251625

Title: The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9.

PubMed ID: 30251625

DOI: 10.7554/elife.38839

PubMed ID: 29643117

Title: SFT-4/Surf4 control ER export of soluble cargo proteins and participate in ER exit site organization.

PubMed ID: 29643117

DOI: 10.1083/jcb.201708115

PubMed ID: 29251827

Title: Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.

PubMed ID: 29251827

DOI: 10.1002/pmic.201700403

PubMed ID: 32989016

Title: The endoplasmic reticulum cargo receptor SURF4 facilitates efficient erythropoietin secretion.

PubMed ID: 32989016

DOI: 10.1128/mcb.00180-20

PubMed ID: 33186557

Title: Receptor-mediated ER export of lipoproteins controls lipid homeostasis in mice and humans.

PubMed ID: 33186557

DOI: 10.1016/j.cmet.2020.10.020

PubMed ID: 34015269

Title: TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.

PubMed ID: 34015269

DOI: 10.1016/j.cmet.2021.05.006

Sequence Information:

  • Length: 269
  • Mass: 30394
  • Checksum: 03366E29882B97A5
  • Sequence:
    • MGQNDLMGTA EDFADQFLRV TKQYLPHVAR LCLISTFLED GIRMWFQWSE QRDYIDTTWN 
CGYLLASSFV FLNLLGQLTG CVLVLSRNFV QYACFGLFGI IALQTIAYSI LWDLKFLMRN 
LALGGGLLLL LAESRSEGKS MFAGVPTMRE SSPKQYMQLG GRVLLVLMFM TLLHFDASFF 
SIVQNIVGTA LMILVAIGFK TKLAALTLVV WLFAINVYFN AFWTIPVYKP MHDFLKYDFF 
QTMSVIGGLL LVVALGPGGV SMDEKKKEW

Genular Protein ID: 1198704673

Symbol: B7Z7A8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z7A8

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 2 SAM 1

Sequence Information:

  • Length: 260
  • Mass: 29458
  • Checksum: 795E288F8EA30C02
  • Sequence:
    • MRSLATEFLR VTKQYLPHVA RLCLISTFLE DGIRMWFQWS EQRDYIDTTW NCGYLLASSF 
VFLNLLGQLT GCVLVLSRNF VQYACFGLFG IIALQTIAYS ILWDLKFLMR NLALGGGLLL 
LLAESRSEGK SMFAGVPTMR ESSPKQYMQL GGRVLLVLMF MTLLHFDASF FSIVQNIVGT 
ALMILVAIGF KTKLAALTLV VWLFAINVYF NAFWTIPVYK PMHDFLKYDF FQTMSVIGGL 
LLVVALGPGG VSMDEKKKEW

Genular Protein ID: 516839150

Symbol: B7Z1G8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z1G8 A0A024R8C4

Database IDs:

ARBA 13 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 5 GO 4 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 226
  • Mass: 25497
  • Checksum: 13E6BAC55DA33F5D
  • Sequence:
    • MWFQWSEQRD YIDTTWNCGY LLASSFVFLN LLGQLTGCVL VLSRNFVQYA CFGLFGIIAL 
QTIAYSILWD LKFLMRNLAL GGGLLLLLAE SRSEGKSMFA GVPTMRESSP KQYMQLGGRV 
LLVLMFMTLL HFDASFFSIV QNIVGTALMI LVAIGFKTKL AALTLVVWLF AINVYFNAFW 
TIPVYKPMHD FLKYDFFQTM SVIGGLLLVV ALGPGGVSMD EKKKEW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.