Details for: TAF6

Gene ID: 6878

Symbol: TAF6

Ensembl ID: ENSG00000106290

Description: TATA-box binding protein associated factor 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 96.6278
    Cell Significance Index: -15.0300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 65.0125
    Cell Significance Index: -16.4900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 41.8535
    Cell Significance Index: -19.7600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 41.2054
    Cell Significance Index: -16.7400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 37.9677
    Cell Significance Index: -19.5300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 17.6487
    Cell Significance Index: -16.8500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.3209
    Cell Significance Index: -18.8900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.9092
    Cell Significance Index: -15.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.9569
    Cell Significance Index: -19.5600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.2000
    Cell Significance Index: -12.9000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3579
    Cell Significance Index: 220.8600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0829
    Cell Significance Index: 977.7400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8264
    Cell Significance Index: 89.8900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7664
    Cell Significance Index: 46.0100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.5236
    Cell Significance Index: 18.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5150
    Cell Significance Index: 50.9400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.4797
    Cell Significance Index: 10.0400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4439
    Cell Significance Index: 23.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4168
    Cell Significance Index: 57.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4015
    Cell Significance Index: 27.7700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3615
    Cell Significance Index: 72.5100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3449
    Cell Significance Index: 40.6800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3396
    Cell Significance Index: 9.2500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.3217
    Cell Significance Index: 8.4600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.3173
    Cell Significance Index: 2.6700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3000
    Cell Significance Index: 163.8600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2626
    Cell Significance Index: 13.7900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2581
    Cell Significance Index: 6.9200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.2555
    Cell Significance Index: 2.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2539
    Cell Significance Index: 45.7700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2516
    Cell Significance Index: 11.7300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2288
    Cell Significance Index: 6.1100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2245
    Cell Significance Index: 27.6000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1997
    Cell Significance Index: 5.7600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1963
    Cell Significance Index: 135.7800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1931
    Cell Significance Index: 8.7500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1846
    Cell Significance Index: 4.0000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1754
    Cell Significance Index: 34.8100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.1739
    Cell Significance Index: 1.8900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1530
    Cell Significance Index: 19.6100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1374
    Cell Significance Index: 60.7600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1216
    Cell Significance Index: 9.0600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1002
    Cell Significance Index: 5.2200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0958
    Cell Significance Index: 34.3500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0830
    Cell Significance Index: 5.2300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0778
    Cell Significance Index: 5.0200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0701
    Cell Significance Index: 2.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0591
    Cell Significance Index: 10.1000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0527
    Cell Significance Index: 6.8100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0460
    Cell Significance Index: 8.7600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0455
    Cell Significance Index: 1.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0434
    Cell Significance Index: 2.0400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0274
    Cell Significance Index: 1.9400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0268
    Cell Significance Index: 0.7500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0143
    Cell Significance Index: 0.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0106
    Cell Significance Index: 0.3400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0005
    Cell Significance Index: -0.9500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0036
    Cell Significance Index: -2.6500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0042
    Cell Significance Index: -2.6100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0053
    Cell Significance Index: -4.0400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0077
    Cell Significance Index: -5.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0097
    Cell Significance Index: -17.8800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0111
    Cell Significance Index: -17.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0151
    Cell Significance Index: -20.5400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0160
    Cell Significance Index: -0.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0169
    Cell Significance Index: -10.7400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0194
    Cell Significance Index: -0.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0205
    Cell Significance Index: -2.0900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0205
    Cell Significance Index: -11.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0362
    Cell Significance Index: -16.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0446
    Cell Significance Index: -9.4000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0552
    Cell Significance Index: -15.8700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0569
    Cell Significance Index: -6.5200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0661
    Cell Significance Index: -9.6100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0676
    Cell Significance Index: -7.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1181
    Cell Significance Index: -7.9400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1296
    Cell Significance Index: -3.3100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.1296
    Cell Significance Index: -1.6600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1485
    Cell Significance Index: -9.1300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1517
    Cell Significance Index: -17.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1697
    Cell Significance Index: -13.0200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1748
    Cell Significance Index: -9.8100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1825
    Cell Significance Index: -19.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1848
    Cell Significance Index: -4.6200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1885
    Cell Significance Index: -3.2300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2074
    Cell Significance Index: -16.4300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2347
    Cell Significance Index: -2.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2685
    Cell Significance Index: -16.4600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2747
    Cell Significance Index: -8.0900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2844
    Cell Significance Index: -3.3900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2913
    Cell Significance Index: -6.7300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3059
    Cell Significance Index: -8.7700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3136
    Cell Significance Index: -13.8700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3317
    Cell Significance Index: -9.4700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3436
    Cell Significance Index: -9.1900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3525
    Cell Significance Index: -4.8100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3542
    Cell Significance Index: -6.2600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3745
    Cell Significance Index: -8.2000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3774
    Cell Significance Index: -14.2900
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.3849
    Cell Significance Index: -5.3400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TAF6 is a highly conserved protein that belongs to the TATA-box binding protein (TBP) associated factor family. It is a subunit of the transcription initiation factor TFIID, which is responsible for the recognition and binding of specific DNA sequences, known as TATA boxes, that serve as promoters for gene transcription. TAF6 is a multifunctional protein that interacts with various transcription factors, including TBP, RNA polymerase II, and other general transcription factors. It is also involved in the regulation of chromatin remodeling and the assembly of the PIC. **Pathways and Functions:** TAF6 plays a critical role in the following pathways and functions: 1. **Transcription Initiation:** TAF6 is essential for the assembly of the PIC and the promotion of transcription initiation by RNA polymerase II. 2. **Cell Cycle Regulation:** TAF6 regulates the expression of genes involved in cell cycle progression, including the tumor suppressor TP53. 3. **DNA Repair:** TAF6 is involved in the regulation of DNA repair pathways, including the repair of double-strand breaks and the maintenance of genome stability. 4. **Apoptosis:** TAF6 has been implicated in the regulation of apoptosis, a process of programmed cell death that is essential for the elimination of damaged or infected cells. 5. **Infectious Disease:** TAF6 plays a role in the regulation of viral replication, including the replication of HIV. **Clinical Significance:** Dysregulation of TAF6 has been implicated in various diseases, including: 1. **Cancer:** TAF6 is often overexpressed in cancer cells, where it promotes the expression of genes involved in cell proliferation and survival. 2. **Infectious Diseases:** TAF6 is involved in the regulation of viral replication, including the replication of HIV, and its dysregulation can lead to increased viral replication and disease severity. 3. **Neurological Disorders:** TAF6 has been implicated in the regulation of gene expression in the brain, and its dysregulation has been linked to neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Reproductive Disorders:** TAF6 is involved in the regulation of gene expression in the reproductive system, and its dysregulation can lead to infertility and reproductive disorders. In conclusion, TAF6 is a crucial regulator of transcription initiation and cell cycle regulation, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the mechanisms by which TAF6 regulates gene expression and its role in disease pathogenesis.

Genular Protein ID: 1032876287

Symbol: TAF6_HUMAN

Name: Transcription initiation factor TFIID subunit 6

UniProtKB Accession Codes:

P49848 A4D2B2 A4D2B3 B4DT11 D6W5U2 Q6AI29

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 11 EMDB 30 Ensembl 27 ExpressionAtlas 1 GO 28 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 32 PDBsum 32 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 10 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8262073

Title: Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID.

PubMed ID: 8262073

DOI: 10.1002/j.1460-2075.1993.tb06226.x

PubMed ID: 7667268

Title: Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.

PubMed ID: 7667268

DOI: 10.1073/pnas.92.18.8195

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11583621

Title: Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function.

PubMed ID: 11583621

DOI: 10.1016/s1097-2765(01)00325-2

PubMed ID: 12601814

Title: Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis.

PubMed ID: 12601814

DOI: 10.1002/pmic.200390030

PubMed ID: 15960975

Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

PubMed ID: 15960975

DOI: 10.1016/j.cell.2005.04.031

PubMed ID: 15601843

Title: Core promoter binding by histone-like TAF complexes.

PubMed ID: 15601843

DOI: 10.1128/mcb.25.1.206-219.2005

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18628956

Title: TAF6delta controls apoptosis and gene expression in the absence of p53.

PubMed ID: 18628956

DOI: 10.1371/journal.pone.0002721

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20096117

Title: TAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53.

PubMed ID: 20096117

DOI: 10.1186/1471-2199-11-10

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25025302

Title: Alternative splicing of TAF6: downstream transcriptome impacts and upstream RNA splice control elements.

PubMed ID: 25025302

DOI: 10.1371/journal.pone.0102399

PubMed ID: 29358700

Title: BIM and NOXA are mitochondrial effectors of TAF6delta-driven apoptosis.

PubMed ID: 29358700

DOI: 10.1038/s41419-017-0115-3

PubMed ID: 25558065

Title: Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families.

PubMed ID: 25558065

DOI: 10.1016/j.celrep.2014.12.015

PubMed ID: 25574841

Title: Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes.

PubMed ID: 25574841

DOI: 10.1172/jci77435

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 33795473

Title: Structural insights into preinitiation complex assembly on core promoters.

PubMed ID: 33795473

DOI: 10.1126/science.aba8490

Sequence Information:

  • Length: 677
  • Mass: 72668
  • Checksum: 06C6BFA563580823
  • Sequence:
    • MAEEKKLKLS NTVLPSESMK VVAESMGIAQ IQEETCQLLT DEVSYRIKEI AQDALKFMHM 
GKRQKLTTSD IDYALKLKNV EPLYGFHAQE FIPFRFASGG GRELYFYEEK EVDLSDIINT 
PLPRVPLDVC LKAHWLSIEG CQPAIPENPP PAPKEQQKAE ATEPLKSAKP GQEEDGPLKG 
KGQGATTADG KGKEKKAPPL LEGAPLRLKP RSIHELSVEQ QLYYKEITEA CVGSCEAKRA 
EALQSIATDP GLYQMLPRFS TFISEGVRVN VVQNNLALLI YLMRMVKALM DNPTLYLEKY 
VHELIPAVMT CIVSRQLCLR PDVDNHWALR DFAARLVAQI CKHFSTTTNN IQSRITKTFT 
KSWVDEKTPW TTRYGSIAGL AELGHDVIKT LILPRLQQEG ERIRSVLDGP VLSNIDRIGA 
DHVQSLLLKH CAPVLAKLRP PPDNQDAYRA EFGSLGPLLC SQVVKARAQA ALQAQQVNRT 
TLTITQPRPT LTLSQAPQPG PRTPGLLKVP GSIALPVQTL VSARAAAPPQ PSPPPTKFIV 
MSSSSSAPST QQVLSLSTSA PGSGSTTTSP VTTTVPSVQP IVKLVSTATT APPSTAPSGP 
GSVQKYIVVS LPPTGEGKGG PTSHPSPVPP PASSPSPLSG SALCGGKQEA GDSPPPAPGT 
PKANGSQPNS GSPQPAP

Genular Protein ID: 1351226276

Symbol: A4D299_HUMAN

Name: N/A

UniProtKB Accession Codes:

A4D299

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 9 Gene3D 2 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 2 RefSeq 5 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

Sequence Information:

  • Length: 667
  • Mass: 71480
  • Checksum: 7913E23A05CFA39C
  • Sequence:
    • MAEEKKLKLS NTVLPSESMK VVAESMGIAQ IQEETCQLLT DEDALKFMHM GKRQKLTTSD 
IDYALKLKNV EPLYGFHAQE FIPFRFASGG GRELYFYEEK EVDLSDIINT PLPRVPLDVC 
LKAHWLSIEG CQPAIPENPP PAPKEQQKAE ATEPLKSAKP GQEEDGPLKG KGQGATTADG 
KGKEKKAPPL LEGAPLRLKP RSIHELSVEQ QLYYKEITEA CVGSCEAKRA EALQSIATDP 
GLYQMLPRFS TFISEGVRVN VVQNNLALLI YLMRMVKALM DNPTLYLEKY VHELIPAVMT 
CIVSRQLCLR PDVDNHWALR DFAARLVAQI CKHFSTTTNN IQSRITKTFT KSWVDEKTPW 
TTRYGSIAGL AELGHDVIKT LILPRLQQEG ERIRSVLDGP VLSNIDRIGA DHVQSLLLKH 
CAPVLAKLRP PPDNQDAYRA EFGSLGPLLC SQVVKARAQA ALQAQQVNRT TLTITQPRPT 
LTLSQAPQPG PRTPGLLKVP GSIALPVQTL VSARAAAPPQ PSPPPTKFIV MSSSSSAPST 
QQVLSLSTSA PGSGSTTTSP VTTTVPSVQP IVKLVSTATT APPSTAPSGP GSVQKYIVVS 
LPPTGEGKGG PTSHPSPVPP PASSPSPLSG SALCGGKQEA GDSPPPAPGT PKANGSQPNS 
GSPQPAP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.