Details for: TARBP2

Gene ID: 6895

Symbol: TARBP2

Ensembl ID: ENSG00000139546

Description: TARBP2 subunit of RISC loading complex

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 64.0328
    Cell Significance Index: -9.9600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 35.0098
    Cell Significance Index: -8.8800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 24.5063
    Cell Significance Index: -11.5700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.0271
    Cell Significance Index: -11.1300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.7329
    Cell Significance Index: -10.0000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.8991
    Cell Significance Index: -11.4400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.5949
    Cell Significance Index: -7.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0610
    Cell Significance Index: 104.9600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8196
    Cell Significance Index: 49.2100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7487
    Cell Significance Index: 47.1900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7339
    Cell Significance Index: 79.8300
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.6413
    Cell Significance Index: 5.1200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.6411
    Cell Significance Index: 6.9700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5952
    Cell Significance Index: 30.9200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5928
    Cell Significance Index: 96.4100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.5843
    Cell Significance Index: 12.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5484
    Cell Significance Index: 14.7000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3699
    Cell Significance Index: 12.8600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.3514
    Cell Significance Index: 4.5000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3284
    Cell Significance Index: 4.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3276
    Cell Significance Index: 9.4400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3236
    Cell Significance Index: 292.1500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3102
    Cell Significance Index: 14.0600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3058
    Cell Significance Index: 8.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2977
    Cell Significance Index: 6.4500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2827
    Cell Significance Index: 19.5500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2720
    Cell Significance Index: 4.0800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2577
    Cell Significance Index: 30.3900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2149
    Cell Significance Index: 10.0200
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.2060
    Cell Significance Index: 4.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2056
    Cell Significance Index: 40.8000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1931
    Cell Significance Index: 34.8100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1847
    Cell Significance Index: 100.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1822
    Cell Significance Index: 4.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1801
    Cell Significance Index: 34.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1610
    Cell Significance Index: 4.5000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1454
    Cell Significance Index: 19.9700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1373
    Cell Significance Index: 3.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1368
    Cell Significance Index: 3.6600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1348
    Cell Significance Index: 59.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1292
    Cell Significance Index: 15.8900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1221
    Cell Significance Index: 3.2600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1218
    Cell Significance Index: 3.9000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0971
    Cell Significance Index: 6.2700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0958
    Cell Significance Index: 2.0400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0864
    Cell Significance Index: 1.0300
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.0724
    Cell Significance Index: 1.1000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0695
    Cell Significance Index: 13.9400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0594
    Cell Significance Index: 4.2000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0449
    Cell Significance Index: 5.7600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0366
    Cell Significance Index: 13.1400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0320
    Cell Significance Index: 0.3000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0305
    Cell Significance Index: 1.0700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0284
    Cell Significance Index: 3.6700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0237
    Cell Significance Index: 1.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0074
    Cell Significance Index: 0.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0065
    Cell Significance Index: 4.9200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0054
    Cell Significance Index: 0.9200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0015
    Cell Significance Index: -2.8400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0018
    Cell Significance Index: -0.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0057
    Cell Significance Index: -10.4200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0071
    Cell Significance Index: -10.9900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0076
    Cell Significance Index: -5.5700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0093
    Cell Significance Index: -12.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0099
    Cell Significance Index: -0.1700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0111
    Cell Significance Index: -7.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0122
    Cell Significance Index: -9.0500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0140
    Cell Significance Index: -1.4400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0140
    Cell Significance Index: -1.0400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0141
    Cell Significance Index: -0.3600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0160
    Cell Significance Index: -9.0000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0199
    Cell Significance Index: -12.4500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0230
    Cell Significance Index: -10.4400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0296
    Cell Significance Index: -8.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0301
    Cell Significance Index: -4.3700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0308
    Cell Significance Index: -0.3500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0420
    Cell Significance Index: -4.8900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0433
    Cell Significance Index: -4.9600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.0556
    Cell Significance Index: -0.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0592
    Cell Significance Index: -12.4600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1078
    Cell Significance Index: -11.2200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1103
    Cell Significance Index: -1.5800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1119
    Cell Significance Index: -6.2800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1130
    Cell Significance Index: -2.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1136
    Cell Significance Index: -8.7200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1174
    Cell Significance Index: -9.3000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1217
    Cell Significance Index: -8.1800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1318
    Cell Significance Index: -8.1000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1581
    Cell Significance Index: -9.6900
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1629
    Cell Significance Index: -2.3400
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1634
    Cell Significance Index: -2.2900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1666
    Cell Significance Index: -2.5100
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: -0.1768
    Cell Significance Index: -0.8600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1785
    Cell Significance Index: -1.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1803
    Cell Significance Index: -5.3100
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.1997
    Cell Significance Index: -1.2500
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.2018
    Cell Significance Index: -2.8000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2086
    Cell Significance Index: -3.8600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2104
    Cell Significance Index: -5.2600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2109
    Cell Significance Index: -9.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit of RISC loading complex:** TARBP2 is a crucial component of the RISC loading complex, which is responsible for loading small interfering RNAs (siRNAs) and microRNAs (miRNAs) into the RISC complex. 2. **RNA-binding protein:** TARBP2 possesses RNA-binding capabilities, allowing it to interact with various RNAs, including siRNAs, miRNAs, and pre-miRNAs. 3. **Regulation of gene silencing:** TARBP2 plays a pivotal role in the regulation of gene silencing by RISC-mediated cleavage of target mRNAs. 4. **Antiviral defense:** TARBP2 is involved in the negative regulation of defense responses to viruses by host cells, highlighting its potential role in preventing viral replication. **Pathways and Functions:** 1. **Antiviral mechanism by IFN-stimulated genes:** TARBP2 is involved in the regulation of antiviral responses mediated by IFN-stimulated genes, which are crucial for defending against viral infections. 2. **Cytokine signaling in the immune system:** TARBP2 is part of the RISC complex, which regulates cytokine signaling pathways, including those involved in immune responses. 3. **Global gene silencing by mRNA cleavage:** TARBP2 facilitates the global silencing of genes by RISC-mediated cleavage of target mRNAs. 4. **Regulation of miRNA biogenesis:** TARBP2 is involved in the regulation of miRNA biogenesis, processing, and binding, highlighting its role in the post-transcriptional regulation of gene expression. **Clinical Significance:** 1. **Viral infections:** TARBP2's role in antiviral defense and gene silencing makes it a potential target for the treatment of viral infections. 2. **Autoimmune diseases:** The regulation of cytokine signaling pathways by TARBP2 may have implications for the treatment of autoimmune diseases, such as rheumatoid arthritis and lupus. 3. **Cancer:** TARBP2's involvement in the regulation of gene silencing and miRNA biogenesis may have implications for the development of cancer therapies. 4. **Neurological disorders:** The regulation of miRNA biogenesis and binding by TARBP2 may have implications for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, TARBP2 is a crucial regulator of immune response and gene silencing, with significant implications for our understanding of antiviral defense, cytokine signaling, and global gene silencing. Further research is needed to fully elucidate the functions and clinical significance of TARBP2.

Genular Protein ID: 3410427334

Symbol: TRBP2_HUMAN

Name: TAR RNA-binding protein 2

UniProtKB Accession Codes:

Q15633 Q12878 Q8WY32 Q8WY33 Q9BRY2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CORUM 1 CTD 1 ChEMBL 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EMBL 7 EMDB 3 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 31 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2011739

Title: Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR.

PubMed ID: 2011739

DOI: 10.1126/science.2011739

PubMed ID: 7774957

Title: Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1).

PubMed ID: 7774957

DOI: 10.1016/0888-7543(95)80110-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11641396

Title: Organization of the human tarbp2 gene reveals two promoters that are repressed in an astrocytic cell line.

PubMed ID: 11641396

DOI: 10.1074/jbc.m104645200

PubMed ID: 8455607

Title: Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufen.

PubMed ID: 8455607

DOI: 10.1128/mcb.13.4.2193-2202.1993

PubMed ID: 11438532

Title: Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression.

PubMed ID: 11438532

DOI: 10.1074/jbc.m103584200

PubMed ID: 12475984

Title: The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR.

PubMed ID: 12475984

DOI: 10.1074/jbc.m208954200

PubMed ID: 16271387

Title: Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.

PubMed ID: 16271387

DOI: 10.1016/j.cell.2005.10.022

PubMed ID: 16142218

Title: TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.

PubMed ID: 16142218

DOI: 10.1038/sj.embor.7400509

PubMed ID: 16357216

Title: A human, ATP-independent, RISC assembly machine fueled by pre-miRNA.

PubMed ID: 16357216

DOI: 10.1101/gad.1384005

PubMed ID: 15973356

Title: TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

PubMed ID: 15973356

DOI: 10.1038/nature03868

PubMed ID: 16424907

Title: The role of PACT in the RNA silencing pathway.

PubMed ID: 16424907

DOI: 10.1038/sj.emboj.7600942

PubMed ID: 17452327

Title: Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA.

PubMed ID: 17452327

DOI: 10.1074/jbc.m611768200

PubMed ID: 17531811

Title: RNA helicase A interacts with RISC in human cells and functions in RISC loading.

PubMed ID: 17531811

DOI: 10.1016/j.molcel.2007.04.016

PubMed ID: 17507929

Title: MicroRNA silencing through RISC recruitment of eIF6.

PubMed ID: 17507929

DOI: 10.1038/nature05841

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18178619

Title: In vitro reconstitution of the human RISC-loading complex.

PubMed ID: 18178619

DOI: 10.1073/pnas.0710869105

PubMed ID: 18421256

Title: Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions.

PubMed ID: 18421256

DOI: 10.4161/rna.5.2.6069

PubMed ID: 19219043

Title: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.

PubMed ID: 19219043

DOI: 10.1038/ng.317

PubMed ID: 26813765

Title: Retraction: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.

PubMed ID: 26813765

DOI: 10.1038/ng0216-221

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21228243

Title: Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway.

PubMed ID: 21228243

DOI: 10.1128/jvi.01160-10

PubMed ID: 23063653

Title: Dicer partner proteins tune the length of mature miRNAs in flies and mammals.

PubMed ID: 23063653

DOI: 10.1016/j.cell.2012.09.027

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30626973

Title: FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing.

PubMed ID: 30626973

DOI: 10.1038/s41586-018-0841-4

PubMed ID: 30927622

Title: TARBP2 inhibits IRF7 activation by suppressing TRAF6-mediated K63-linked ubiquitination of IRF7.

PubMed ID: 30927622

DOI: 10.1016/j.molimm.2019.02.019

Sequence Information:

  • Length: 366
  • Mass: 39039
  • Checksum: 768BA11751DA4912
  • Sequence:
    • MSEEEQGSGT TTGCGLPSIE QMLAANPGKT PISLLQEYGT RIGKTPVYDL LKAEGQAHQP 
NFTFRVTVGD TSCTGQGPSK KAAKHKAAEV ALKHLKGGSM LEPALEDSSS FSPLDSSLPE 
DIPVFTAAAA ATPVPSVVLT RSPPMELQPP VSPQQSECNP VGALQELVVQ KGWRLPEYTV 
TQESGPAHRK EFTMTCRVER FIEIGSGTSK KLAKRNAAAK MLLRVHTVPL DARDGNEVEP 
DDDHFSIGVG SRLDGLRNRG PGCTWDSLRN SVGEKILSLR SCSLGSLGAL GPACCRVLSE 
LSEEQAFHVS YLDIEELSLS GLCQCLVELS TQPATVCHGS ATTREAARGE AARRALQYLK 
IMAGSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.