Details for: TBXA2R
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 21.1514
Cell Significance Index: -3.2900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 10.9208
Cell Significance Index: -2.7700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 7.5322
Cell Significance Index: -3.0600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 7.1697
Cell Significance Index: -3.3900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 6.8237
Cell Significance Index: -3.5100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 2.6684
Cell Significance Index: -3.2900 - Cell Name: glomerular capillary endothelial cell (CL1001005)
Fold Change: 2.4765
Cell Significance Index: 9.2300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.4335
Cell Significance Index: 65.2100 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.7548
Cell Significance Index: 12.1100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.4087
Cell Significance Index: 26.3700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2743
Cell Significance Index: 14.2900 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.2594
Cell Significance Index: 3.6400 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.1970
Cell Significance Index: 1.8700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1371
Cell Significance Index: 8.6400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0915
Cell Significance Index: 1.3100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0719
Cell Significance Index: 1.2700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0566
Cell Significance Index: 0.9700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0501
Cell Significance Index: 6.4200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.0442
Cell Significance Index: 0.6400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.0150
Cell Significance Index: 0.1700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0134
Cell Significance Index: 4.8000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0128
Cell Significance Index: 0.3300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0106
Cell Significance Index: 2.1300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.0099
Cell Significance Index: 0.0600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0091
Cell Significance Index: 1.8100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0080
Cell Significance Index: 5.5300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0002
Cell Significance Index: -0.3300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0011
Cell Significance Index: -1.6800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0012
Cell Significance Index: -2.1600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0023
Cell Significance Index: -3.1400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0028
Cell Significance Index: -1.2600 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.0030
Cell Significance Index: -0.0300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0043
Cell Significance Index: -2.7400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0045
Cell Significance Index: -3.4000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0046
Cell Significance Index: -3.4000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0049
Cell Significance Index: -3.6700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0060
Cell Significance Index: -1.7400 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0060
Cell Significance Index: -3.3000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0063
Cell Significance Index: -2.8500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0065
Cell Significance Index: -3.6800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0070
Cell Significance Index: -4.3700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0074
Cell Significance Index: -1.0100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0078
Cell Significance Index: -1.4000 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: -0.0101
Cell Significance Index: -0.0800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0114
Cell Significance Index: -1.6500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0149
Cell Significance Index: -2.5400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0180
Cell Significance Index: -3.7900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0193
Cell Significance Index: -2.3700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0232
Cell Significance Index: -2.3700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0257
Cell Significance Index: -3.3200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0260
Cell Significance Index: -1.6000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0280
Cell Significance Index: -3.2600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0288
Cell Significance Index: -3.3000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0301
Cell Significance Index: -3.1400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0310
Cell Significance Index: -3.6500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0371
Cell Significance Index: -2.8500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0381
Cell Significance Index: -1.0200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0452
Cell Significance Index: -3.3700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0452
Cell Significance Index: -3.0400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0479
Cell Significance Index: -1.3400 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: -0.0526
Cell Significance Index: -0.5600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0532
Cell Significance Index: -1.3600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0541
Cell Significance Index: -2.8100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0562
Cell Significance Index: -2.6200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0615
Cell Significance Index: -1.0300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0618
Cell Significance Index: -3.4700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0619
Cell Significance Index: -2.9100 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.0636
Cell Significance Index: -1.5400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0638
Cell Significance Index: -2.8200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0644
Cell Significance Index: -3.3800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0688
Cell Significance Index: -2.1900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0702
Cell Significance Index: -2.4600 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0732
Cell Significance Index: -1.4700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0733
Cell Significance Index: -2.4000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0747
Cell Significance Index: -2.8300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0755
Cell Significance Index: -3.4200 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.0825
Cell Significance Index: -0.4500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0825
Cell Significance Index: -1.6100 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.0843
Cell Significance Index: -0.8700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0938
Cell Significance Index: -2.3400 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0950
Cell Significance Index: -4.1300 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.0960
Cell Significance Index: -0.9500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0987
Cell Significance Index: -3.4300 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0993
Cell Significance Index: -3.1400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1008
Cell Significance Index: -2.8900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1008
Cell Significance Index: -3.7000 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1014
Cell Significance Index: -2.1900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1022
Cell Significance Index: -2.1400 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -0.1044
Cell Significance Index: -0.7500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1047
Cell Significance Index: -3.6800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1052
Cell Significance Index: -3.0900 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.1052
Cell Significance Index: -1.4400 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.1062
Cell Significance Index: -2.0900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1062
Cell Significance Index: -2.1000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1070
Cell Significance Index: -5.4000 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.1081
Cell Significance Index: -1.3700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1093
Cell Significance Index: -3.2200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1095
Cell Significance Index: -2.9800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1098
Cell Significance Index: -2.3300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1114
Cell Significance Index: -3.1800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2728433353
Symbol: TA2R_HUMAN
Name: Thromboxane A2 receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1825698
Title: Cloning and expression of cDNA for a human thromboxane A2 receptor.
PubMed ID: 1825698
DOI: 10.1038/349617a0
PubMed ID: 8227091
Title: Characterization and chromosomal mapping of the human thromboxane A2 receptor gene.
PubMed ID: 8227091
PubMed ID: 8034687
Title: Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor.
PubMed ID: 8034687
PubMed ID: 7896853
PubMed ID: 7965765
Title: Cloning and pharmacologic characterization of a thromboxane A2 receptor from K562 (human chronic myelogenous leukemia) cells.
PubMed ID: 7965765
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8613548
Title: Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation.
PubMed ID: 8613548
DOI: 10.1172/jci118518
PubMed ID: 8246916
Title: Point mutation in the seventh hydrophobic domain of the human thromboxane A2 receptor allows discrimination between agonist and antagonist binding sites.
PubMed ID: 8246916
PubMed ID: 17499743
Title: Low expression of cell-surface thromboxane A2 receptor beta-isoform through the negative regulation of its membrane traffic by proteasomes.
PubMed ID: 17499743
PubMed ID: 18088317
Title: RACK1 regulates the cell surface expression of the G protein-coupled receptor for thromboxane A(2).
PubMed ID: 18088317
PubMed ID: 19464661
Title: Thromboxane A2-induced signal transduction is negatively regulated by KIAA1005 that directly interacts with thromboxane A2 receptor.
PubMed ID: 19464661
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 7929844
Title: Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder.
PubMed ID: 7929844
DOI: 10.1172/jci117510
Sequence Information:
- Length: 343
- Mass: 37431
- Checksum: 114A7C3F3F0D35F1
- Sequence:
MWPNGSSLGP CFRPTNITLE ERRLIASPWF AASFCVVGLA SNLLALSVLA GARQGGSHTR SSFLTFLCGL VLTDFLGLLV TGTIVVSQHA ALFEWHAVDP GCRLCRFMGV VMIFFGLSPL LLGAAMASER YLGITRPFSR PAVASQRRAW ATVGLVWAAA LALGLLPLLG VGRYTVQYPG SWCFLTLGAE SGDVAFGLLF SMLGGLSVGL SFLLNTVSVA TLCHVYHGQE AAQQRPRDSE VEMMAQLLGI MVVASVCWLP LLVFIAQTVL RNPPAMSPAG QLSRTTEKEL LIYLRVATWN QILDPWVYIL FRRAVLRRLQ PRLSTRPRSL SLQPQLTQRS GLQ
Genular Protein ID: 4223167969
Symbol: Q0VAB0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 259
- Mass: 26619
- Checksum: D2BA8D736E967010
- Sequence:
MWPNGSSLGP CFRPTNITLE ERRLIASPWF AASFCVVGLA SNLLALSVLA GARQGGSHTR SSFLTFLCGL VLTDFLGLLV TGTIVVSQHA ALFEWHAVDP GCRLCRFMGV VMIFFGLSPL LLGAAMASER YLGLHCPDSA AKPACHEPRR AAVPHHGEGA AHLLARGHLE PDPGPLGVYP VPPRRAPASP ASPQHPAQVA VPPAPAHAAL RAAVGSGQSA PPAPFRGALG PSDSPSACSE DSGAGGAGWT VGISSRVLG
Genular Protein ID: 395275013
Symbol: Q05C92_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 156
- Mass: 16772
- Checksum: 30C541B7BC25706E
- Sequence:
MWPNGSSLGP CFRPTNITLE ERRLIASPWF AASFCVVGLA SNLLALSVLA GARQGGSHTR SSFLTFLCGL VLTDFLGLLV TGTIVVSQHA ALFEWHAVDP GCRLCRFMGV VMIFFGLSPL LLGAAMASER YLGITRPFSR PAVASQRRAW ATVGLV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.