Details for: TPM3

Gene ID: 7170

Symbol: TPM3

Ensembl ID: ENSG00000143549

Description: tropomyosin 3

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 4.01
    Marker Score: 12641
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.97
    Marker Score: 222161.5
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.95
    Marker Score: 45886
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.91
    Marker Score: 38725
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 3.52
    Marker Score: 15106.5
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 3.52
    Marker Score: 5186
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 3.5
    Marker Score: 3378
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 3.48
    Marker Score: 4200
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 3.46
    Marker Score: 183102.5
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 3.42
    Marker Score: 3007
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 3.29
    Marker Score: 9235
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 3.28
    Marker Score: 7991
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 3.24
    Marker Score: 9453.5
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 3.17
    Marker Score: 2980.5
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 3.17
    Marker Score: 6171.5
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 3.1
    Marker Score: 41702
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 3.07
    Marker Score: 5483
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 3.06
    Marker Score: 7385
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 3.04
    Marker Score: 4189
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 3.03
    Marker Score: 3465
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 3.03
    Marker Score: 8363
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 3.01
    Marker Score: 2675
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.94
    Marker Score: 1267
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2.92
    Marker Score: 9167
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.88
    Marker Score: 2263
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 2.85
    Marker Score: 2333
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 2.84
    Marker Score: 1664
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 2.84
    Marker Score: 3152
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 2.83
    Marker Score: 5934
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.83
    Marker Score: 4000
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 2.79
    Marker Score: 1638
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.79
    Marker Score: 5458
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.78
    Marker Score: 2603
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.76
    Marker Score: 17615
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.75
    Marker Score: 2004.5
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.73
    Marker Score: 2069
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 2.72
    Marker Score: 1138.5
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 2.72
    Marker Score: 6778
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.7
    Marker Score: 645
  • Cell Name: naive T cell (CL0000898)
    Fold Change: 2.69
    Marker Score: 1733
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.69
    Marker Score: 3907
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 2.69
    Marker Score: 1950
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 2.69
    Marker Score: 2281
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.68
    Marker Score: 2256
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 2.67
    Marker Score: 931.5
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.67
    Marker Score: 27053
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 2.66
    Marker Score: 1623
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 2.66
    Marker Score: 5310
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 2.66
    Marker Score: 2372
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.66
    Marker Score: 1600
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 2.64
    Marker Score: 4537
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 2.63
    Marker Score: 1135.5
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2.63
    Marker Score: 2586
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 2.62
    Marker Score: 1763
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 2.62
    Marker Score: 1345
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 2.62
    Marker Score: 1894.5
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.61
    Marker Score: 2615
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.61
    Marker Score: 4551.5
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.61
    Marker Score: 7730
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.6
    Marker Score: 2335
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 2.6
    Marker Score: 2799
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.58
    Marker Score: 2801
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.57
    Marker Score: 2028
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 2.57
    Marker Score: 1153
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 2.57
    Marker Score: 1884
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 2.57
    Marker Score: 845
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 2.57
    Marker Score: 908
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.56
    Marker Score: 88834
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.54
    Marker Score: 10391.5
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 2.54
    Marker Score: 6451.5
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 2.53
    Marker Score: 1736
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 2.52
    Marker Score: 6543
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 2.51
    Marker Score: 16007
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.51
    Marker Score: 1253
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.5
    Marker Score: 64114
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.5
    Marker Score: 1663
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 2.49
    Marker Score: 2140
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.48
    Marker Score: 3589
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 2.48
    Marker Score: 1368
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: 2.47
    Marker Score: 2730
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 2.46
    Marker Score: 1777
  • Cell Name: platelet (CL0000233)
    Fold Change: 2.45
    Marker Score: 1107
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.45
    Marker Score: 950
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.44
    Marker Score: 5966.5
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 2.43
    Marker Score: 2022
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 2.43
    Marker Score: 1496
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 2.42
    Marker Score: 1276
  • Cell Name: muscle precursor cell (CL0000680)
    Fold Change: 2.42
    Marker Score: 626
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 2.41
    Marker Score: 1384
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 2.4
    Marker Score: 999
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 2.4
    Marker Score: 1587.5
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 2.37
    Marker Score: 2141
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 2.36
    Marker Score: 626
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 2.36
    Marker Score: 731.5
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 2.35
    Marker Score: 596
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 2.35
    Marker Score: 525
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.35
    Marker Score: 9758
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 2.34
    Marker Score: 473
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 2.33
    Marker Score: 2054
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.33
    Marker Score: 1764

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Other Information

**Key Characteristics:** TPM3 is a member of the tropomyosin family, which is a class of proteins that bind to actin filaments and regulate their dynamics. TPM3 is specifically expressed in mature gamma-delta T cells, CD14-positive classical monocytes, and other immune cells, suggesting its importance in immune cell function and development. Its expression is also found in smooth muscle cells, indicating its role in muscle contraction and relaxation. **Pathways and Functions:** TPM3 is involved in several key signaling pathways, including: 1. **Actin filament organization:** TPM3 regulates the organization and dynamics of actin filaments, which is essential for cell shape, motility, and division. 2. **Muscle contraction:** TPM3 is a key component of the actin filament tropomyosin complex, which regulates muscle contraction and relaxation. 3. **Signal transduction:** TPM3 interacts with various signaling molecules, including Rho GTPases, to regulate signal transduction pathways. 4. **Cytoskeleton remodeling:** TPM3 regulates the remodeling of the cytoskeleton in response to changes in the cell environment. **Clinical Significance:** The dysregulation of TPM3 has been implicated in various diseases, including: 1. **Immunodeficiency:** TPM3 mutations have been associated with immunodeficiency disorders, such as gamma-delta T cell deficiency. 2. **Cancer:** TPM3 is overexpressed in certain types of cancer, including breast and lung cancer, suggesting its role in tumor progression and metastasis. 3. **Muscular dystrophy:** TPM3 mutations have been associated with muscular dystrophy, a group of genetic disorders characterized by progressive muscle weakness and degeneration. In conclusion, TPM3 is a critical component of the actin cytoskeleton, playing a vital role in immune cell signaling and regulation of actin filament dynamics. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms underlying TPM3 function and its role in human disease. **Potential Research Directions:** 1. **Investigating TPM3 function in immune cell signaling:** Further studies are needed to elucidate the specific mechanisms by which TPM3 regulates immune cell signaling and function. 2. **Exploring the role of TPM3 in cancer:** TPM3 overexpression has been observed in certain types of cancer; further research is needed to understand its role in tumor progression and metastasis. 3. **Developing TPM3-based therapeutic strategies:** TPM3-targeted therapies may offer new avenues for treating diseases associated with TPM3 dysregulation. By continuing to explore the functions and mechanisms of TPM3, we can gain a deeper understanding of its role in immune cell signaling and regulation of actin filament dynamics, ultimately leading to the development of novel therapeutic strategies for various diseases.

Genular Protein ID: 3540285006

Symbol: TPM3_HUMAN

Name: Tropomyosin alpha-3 chain

UniProtKB Accession Codes:

P06753 D3DV71 P12324 Q2QD06 Q5VU58 Q5VU63 Q5VU66 Q5VU71 Q5VU72 Q8TCG3 Q969Q2 Q9NQH8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DOSAC-COBS-2DPAGE 1 DisGeNET 1 DrugBank 1 EMBL 16 EPD 1 Ensembl 8 ExpressionAtlas 1 GO 10 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 6 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 6 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 2 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 Pumba 1 RNAct 1 Reactome 4 RefSeq 7 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 7 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3018581

Title: Tissue-specific expression of the human tropomyosin gene involved in the generation of the trk oncogene.

PubMed ID: 3018581

DOI: 10.1038/322648a0

PubMed ID: 3024106

Title: The mRNA and RNA-copy pseudogenes encoding TM30nm, a human cytoskeletal tropomyosin.

PubMed ID: 3024106

DOI: 10.1093/nar/14.21.8413

PubMed ID: 3418707

Title: Organization of the hTMnm gene. Implications for the evolution of muscle and non-muscle tropomyosins.

PubMed ID: 3418707

DOI: 10.1016/0022-2836(88)90633-x

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16201836

Title: Emergence of young human genes after a burst of retroposition in primates.

PubMed ID: 16201836

DOI: 10.1371/journal.pbio.0030357

PubMed ID: 2869410

Title: A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences.

PubMed ID: 2869410

DOI: 10.1038/319743a0

PubMed ID: 1286667

Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.

PubMed ID: 1286667

DOI: 10.1002/elps.11501301199

PubMed ID: 12574106

Title: Altered tropomyosin expression in essential hypertension.

PubMed ID: 12574106

DOI: 10.1161/01.hyp.0000050646.79785.7c

PubMed ID: 8002995

Title: Erythrocyte tropomodulin binds to the N-terminus of hTM5, a tropomyosin isoform encoded by the gamma-tropomyosin gene.

PubMed ID: 8002995

DOI: 10.1006/bbrc.1994.1747

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 35510366

Title: Autosomal dominantly inherited myopathy likely caused by the TNNT1 variant p.(Asp65Ala).

PubMed ID: 35510366

DOI: 10.1002/humu.24397

PubMed ID: 7704029

Title: A mutation in the alpha tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy.

PubMed ID: 7704029

DOI: 10.1038/ng0195-75

PubMed ID: 7663526

Title:

PubMed ID: 7663526

DOI: 10.1038/ng0695-249

PubMed ID: 10587521

Title: A nemaline myopathy mutation in alpha-tropomyosin causes defective regulation of striated muscle force production.

PubMed ID: 10587521

DOI: 10.1172/jci7842

PubMed ID: 17376686

Title: A second pedigree with autosomal dominant nemaline myopathy caused by TPM3 mutation: a clinical and pathological study.

PubMed ID: 17376686

DOI: 10.1016/j.nmd.2007.01.017

PubMed ID: 18300303

Title: Mutations in TPM3 are a common cause of congenital fiber type disproportion.

PubMed ID: 18300303

DOI: 10.1002/ana.21308

PubMed ID: 18382475

Title: Identification of a founder mutation in TPM3 in nemaline myopathy patients of Turkish origin.

PubMed ID: 18382475

DOI: 10.1038/ejhg.2008.60

PubMed ID: 19487656

Title: TPM3 mutation in one of the original cases of cap disease.

PubMed ID: 19487656

DOI: 10.1212/wnl.0b013e3181a82659

PubMed ID: 19553118

Title: A TPM3 mutation causing cap myopathy.

PubMed ID: 19553118

DOI: 10.1016/j.nmd.2009.06.365

PubMed ID: 19953533

Title: Mutations of tropomyosin 3 (TPM3) are common and associated with type 1 myofiber hypotrophy in congenital fiber type disproportion.

PubMed ID: 19953533

DOI: 10.1002/humu.21157

PubMed ID: 20951040

Title: Congenital fibre type disproportion associated with mutations in the tropomyosin 3 (TPM3) gene mimicking congenital myasthenia.

PubMed ID: 20951040

DOI: 10.1016/j.nmd.2010.07.274

PubMed ID: 24692096

Title: Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies.

PubMed ID: 24692096

DOI: 10.1002/humu.22554

PubMed ID: 24239060

Title: Novel TPM3 mutation in a family with cap myopathy and review of the literature.

PubMed ID: 24239060

DOI: 10.1016/j.nmd.2013.10.002

Sequence Information:

  • Length: 285
  • Mass: 32950
  • Checksum: 99EAD24C45460A14
  • Sequence:
    • MMEAIKKKMQ MLKLDKENAL DRAEQAEAEQ KQAEERSKQL EDELAAMQKK LKGTEDELDK 
YSEALKDAQE KLELAEKKAA DAEAEVASLN RRIQLVEEEL DRAQERLATA LQKLEEAEKA 
ADESERGMKV IENRALKDEE KMELQEIQLK EAKHIAEEAD RKYEEVARKL VIIEGDLERT 
EERAELAESK CSELEEELKN VTNNLKSLEA QAEKYSQKED KYEEEIKILT DKLKEAETRA 
EFAERSVAKL EKTIDDLEDE LYAQKLKYKA ISEELDHALN DMTSI

Genular Protein ID: 133058018

Symbol: B4DQ80_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DQ80

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 2 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 182
  • Mass: 21353
  • Checksum: DC4A3CC3AA4CFACE
  • Sequence:
    • MMQRSELSAS SEKLREKGGP GNRGMKVIEN RALKDEEKME LQEIQLKEAK HIAEEADRKY 
EEVARKLVII EGDLERTEER AELAESRCRE MDEQIRLMDQ NLKCLSAAEE KYSQKEDKYE 
EEIKILTDKL KEAETRAEFA ERSVAKLEKT IDDLEDKLKC TKEEHLCTQR MLDQTLLDLN 
EM

Genular Protein ID: 2590678553

Symbol: A0A0S2Z4G4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z4G4

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 3 Gene3D 2 GenomeRNAi 1 IntAct 1 InterPro 2 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 248
  • Mass: 29033
  • Checksum: 5C049312A337BC19
  • Sequence:
    • MAGITTIEAV KRKIQVLQQQ ADDAEERAER LQREVEGERR AREQAEAEVA SLNRRIQLVE 
EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRALK DEEKMELQEI QLKEAKHIAE 
EADRKYEEVA RKLVIIEGDL ERTEERAELA ESRCREMDEQ IRLMDQNLKC LSAAEEKYSQ 
KEDKYEEEIK ILTDKLKEAE TRAEFAERSV AKLEKTIDDL EDKLKCTKEE HLCTQRMLDQ 
TLLDLNEM

Genular Protein ID: 2632101398

Symbol: A0A087WWU8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WWU8

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 227
  • Mass: 26421
  • Checksum: 0DE260B63E0F1E4D
  • Sequence:
    • MAGITTIEAV KRKIQVLQQQ ADDAEERAER LQREVEGERR AREQAEAEVA SLNRRIQLVE 
EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRALK DEEKMELQEI QLKEAKHIAE 
EADRKYEEVA RKLVIIEGDL ERTEERAELA ESRCREMDEQ IRLMDQNLKC LSAAEEKAET 
RAEFAERSVA KLEKTIDDLE DKLKCTKEEH LCTQRMLDQT LLDLNEM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.