Details for: UBTF

Gene ID: 7343

Symbol: UBTF

Ensembl ID: ENSG00000108312

Description: upstream binding transcription factor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 261.5317
    Cell Significance Index: -40.6800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 173.2452
    Cell Significance Index: -43.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 101.9438
    Cell Significance Index: -48.1300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 92.2445
    Cell Significance Index: -37.4800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 88.1441
    Cell Significance Index: -45.3400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 71.9723
    Cell Significance Index: -48.3000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 39.8851
    Cell Significance Index: -38.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.8254
    Cell Significance Index: -47.8700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.7306
    Cell Significance Index: -42.1400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.5391
    Cell Significance Index: -49.4800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.7516
    Cell Significance Index: -26.8800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.0234
    Cell Significance Index: -17.5600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.0738
    Cell Significance Index: 337.2800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.6301
    Cell Significance Index: 84.9100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.4641
    Cell Significance Index: 23.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2931
    Cell Significance Index: 140.6500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1712
    Cell Significance Index: 15.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.1687
    Cell Significance Index: 136.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8247
    Cell Significance Index: 148.6800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7302
    Cell Significance Index: 100.2700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7245
    Cell Significance Index: 46.7400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7171
    Cell Significance Index: 88.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6762
    Cell Significance Index: 298.9600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6342
    Cell Significance Index: 43.8600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5702
    Cell Significance Index: 40.3300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5622
    Cell Significance Index: 112.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5479
    Cell Significance Index: 64.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5425
    Cell Significance Index: 24.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5244
    Cell Significance Index: 286.3800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4738
    Cell Significance Index: 13.6500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4594
    Cell Significance Index: 21.4200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4281
    Cell Significance Index: 42.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3728
    Cell Significance Index: 73.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3393
    Cell Significance Index: 7.3500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3181
    Cell Significance Index: 219.9900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3054
    Cell Significance Index: 109.5600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3013
    Cell Significance Index: 38.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2487
    Cell Significance Index: 6.7700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1819
    Cell Significance Index: 6.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1106
    Cell Significance Index: 3.0900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0821
    Cell Significance Index: 15.6200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0763
    Cell Significance Index: 4.8100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0473
    Cell Significance Index: 0.9900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0461
    Cell Significance Index: 41.6700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0353
    Cell Significance Index: 1.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0305
    Cell Significance Index: 1.7100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0202
    Cell Significance Index: 14.8400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0062
    Cell Significance Index: 3.9500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0032
    Cell Significance Index: 6.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0212
    Cell Significance Index: -39.1000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0257
    Cell Significance Index: -34.9300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0303
    Cell Significance Index: -46.6600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0434
    Cell Significance Index: -2.6700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0461
    Cell Significance Index: -34.8700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0672
    Cell Significance Index: -3.1600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0690
    Cell Significance Index: -51.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0771
    Cell Significance Index: -34.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0869
    Cell Significance Index: -49.0300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0938
    Cell Significance Index: -58.5900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0957
    Cell Significance Index: -2.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1024
    Cell Significance Index: -10.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1109
    Cell Significance Index: -18.9300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1249
    Cell Significance Index: -2.0900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1313
    Cell Significance Index: -37.7700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1532
    Cell Significance Index: -1.7400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1856
    Cell Significance Index: -21.2600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1898
    Cell Significance Index: -24.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1979
    Cell Significance Index: -10.3900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2243
    Cell Significance Index: -32.6000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2597
    Cell Significance Index: -19.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2789
    Cell Significance Index: -9.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2831
    Cell Significance Index: -59.6300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3248
    Cell Significance Index: -21.8400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3302
    Cell Significance Index: -24.6100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3653
    Cell Significance Index: -8.4400
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.3997
    Cell Significance Index: -5.6800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4027
    Cell Significance Index: -31.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4711
    Cell Significance Index: -49.0500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5077
    Cell Significance Index: -12.9700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5223
    Cell Significance Index: -13.7400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5461
    Cell Significance Index: -33.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5643
    Cell Significance Index: -14.1100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5983
    Cell Significance Index: -16.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6146
    Cell Significance Index: -18.0500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6210
    Cell Significance Index: -19.8900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.6937
    Cell Significance Index: -13.5400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7361
    Cell Significance Index: -32.5600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7396
    Cell Significance Index: -12.6800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.8251
    Cell Significance Index: -8.9700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8532
    Cell Significance Index: -21.9300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.8681
    Cell Significance Index: -25.5700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.9068
    Cell Significance Index: -8.3500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.9090
    Cell Significance Index: -9.4100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9264
    Cell Significance Index: -35.0800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.0162
    Cell Significance Index: -29.1300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.0345
    Cell Significance Index: -29.5200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.1157
    Cell Significance Index: -24.4300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.1277
    Cell Significance Index: -24.0200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.1682
    Cell Significance Index: -31.3000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -1.1806
    Cell Significance Index: -9.1000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** UBTF is a transcription factor that belongs to the USF (upstream stimulatory factor) family. It is characterized by its ability to bind to specific DNA sequences, particularly those containing the GC-rich motif. UBTF is also known as Nucleolar transcription factor 1 (NUTF1) and is encoded by the UBTF gene (ENSG00000108312). The UBTF protein is composed of four zinc fingers, which enable it to recognize and interact with specific DNA sequences. Its expression is tightly regulated, with a significant increase in mRNA levels during cell proliferation and differentiation. **Pathways and Functions:** UBTF's primary function is to regulate the transcription of rRNA genes, which are essential for protein synthesis. It interacts with RNA polymerase I to facilitate the initiation of transcription, thereby ensuring the production of rRNA. UBTF's role in rRNA expression is critical for cell growth, proliferation, and differentiation. Beyond its function in rRNA expression, UBTF is involved in various other biological pathways, including: 1. **Epigenetic regulation**: UBTF interacts with histone-modifying enzymes to regulate chromatin structure and gene expression. 2. **Cell differentiation**: UBTF plays a crucial role in the differentiation of immune cells, such as T cells and B cells. 3. **Immune responses**: UBTF is expressed in immune cells, where it regulates the transcription of genes involved in immune responses. 4. **Gene expression**: UBTF modulates the expression of genes involved in various cellular processes, including cell growth, proliferation, and survival. **Clinical Significance:** UBTF's dysregulation has been implicated in various diseases, including: 1. **Immune disorders**: UBTF's role in immune cell differentiation and function makes it a potential target for therapies in immune-related disorders, such as autoimmune diseases and cancer. 2. **Cancer**: UBTF's overexpression has been linked to cancer progression and metastasis. 3. **Neurological disorders**: UBTF's expression in neural cells suggests its potential involvement in neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Reproductive disorders**: UBTF's role in ovarian function and fertility makes it a potential target for therapies in reproductive disorders. In conclusion, UBTF is a multifaceted gene that plays a critical role in regulating gene expression across various cellular contexts. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms of UBTF's function and its potential as a therapeutic target.

Genular Protein ID: 3653447889

Symbol: UBF1_HUMAN

Name: Nucleolar transcription factor 1

UniProtKB Accession Codes:

P17480 A8K6R8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 6 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 6 Ensembl 10 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 8 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2330041

Title: Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins.

PubMed ID: 2330041

DOI: 10.1038/344830a0

PubMed ID: 1940801

Title: Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor.

PubMed ID: 1940801

DOI: 10.1084/jem.174.5.1239

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7982918

Title: The RNA polymerase I transcription factor, upstream binding factor, interacts directly with the TATA box-binding protein.

PubMed ID: 7982918

DOI: 10.1016/s0021-9258(18)43788-x

PubMed ID: 7491500

Title: Coactivator and promoter-selective properties of RNA polymerase I TAFs.

PubMed ID: 7491500

DOI: 10.1126/science.270.5241.1506

PubMed ID: 11250903

Title: hRRN3 is essential in the SL1-mediated recruitment of RNA polymerase I to rRNA gene promoters.

PubMed ID: 11250903

DOI: 10.1093/emboj/20.6.1373

PubMed ID: 11283244

Title: A step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription.

PubMed ID: 11283244

DOI: 10.1128/mcb.21.8.2641-2649.2001

PubMed ID: 16858408

Title: UBF activates RNA polymerase I transcription by stimulating promoter escape.

PubMed ID: 16858408

DOI: 10.1038/sj.emboj.7601221

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20075868

Title: Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size.

PubMed ID: 20075868

DOI: 10.1038/emboj.2009.404

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21930779

Title: Identification of DHX33 as a mediator of rRNA synthesis and cell growth.

PubMed ID: 21930779

DOI: 10.1128/mcb.05832-11

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23972994

Title: ABH2 couples regulation of ribosomal DNA transcription with DNA alkylation repair.

PubMed ID: 23972994

DOI: 10.1016/j.celrep.2013.07.027

PubMed ID: 23229552

Title: PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis.

PubMed ID: 23229552

DOI: 10.1074/jbc.m112.414839

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26089203

Title: The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development.

PubMed ID: 26089203

DOI: 10.1093/hmg/ddv213

PubMed ID: 27729611

Title: PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.

PubMed ID: 27729611

DOI: 10.18632/oncotarget.12288

PubMed ID: 36271492

Title: The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.

PubMed ID: 36271492

DOI: 10.26508/lsa.202201568

PubMed ID: 28777933

Title: Heterozygous de novo UBTF gain-of-function variant is associated with neurodegeneration in childhood.

PubMed ID: 28777933

DOI: 10.1016/j.ajhg.2017.07.002

PubMed ID: 11969401

Title: Solution structure of the first HMG box domain in human upstream binding factor.

PubMed ID: 11969401

DOI: 10.1021/bi015977a

PubMed ID: 12590579

Title: Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor.

PubMed ID: 12590579

DOI: 10.1021/bi026372x

Sequence Information:

  • Length: 764
  • Mass: 89406
  • Checksum: D4F0F8BB180E757D
  • Sequence:
    • MNGEADCPTD LEMAAPKGQD RWSQEDMLTL LECMKNNLPS NDSSKFKTTE SHMDWEKVAF 
KDFSGDMCKL KWVEISNEVR KFRTLTELIL DAQEHVKNPY KGKKLKKHPD FPKKPLTPYF 
RFFMEKRAKY AKLHPEMSNL DLTKILSKKY KELPEKKKMK YIQDFQREKQ EFERNLARFR 
EDHPDLIQNA KKSDIPEKPK TPQQLWYTHE KKVYLKVRPD ATTKEVKDSL GKQWSQLSDK 
KRLKWIHKAL EQRKEYEEIM RDYIQKHPEL NISEEGITKS TLTKAERQLK DKFDGRPTKP 
PPNSYSLYCA ELMANMKDVP STERMVLCSQ QWKLLSQKEK DAYHKKCDQK KKDYEVELLR 
FLESLPEEEQ QRVLGEEKML NINKKQATSP ASKKPAQEGG KGGSEKPKRP VSAMFIFSEE 
KRRQLQEERP ELSESELTRL LARMWNDLSE KKKAKYKARE AALKAQSERK PGGEREERGK 
LPESPKRAEE IWQQSVIGDY LARFKNDRVK ALKAMEMTWN NMEKKEKLMW IKKAAEDQKR 
YERELSEMRA PPAATNSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI 
GSRWQRISQS QKEHYKKLAE EQQKQYKVHL DLWVKSLSPQ DRAAYKEYIS NKRKSMTKLR 
GPNPKSSRTT LQSKSESEED DEEDEDDEDE DEEEEDDENG DSSEDGGDSS ESSSEDESED 
GDENEEDDED EDDDEDDDED EDNESEGSSS SSSSSGDSSD SDSN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.