Details for: VDAC2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 513.6770
Cell Significance Index: -79.9000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 268.2112
Cell Significance Index: -68.0300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 229.6166
Cell Significance Index: -94.5900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 197.1098
Cell Significance Index: -93.0600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 195.8858
Cell Significance Index: -79.5800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 177.0852
Cell Significance Index: -91.0900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 139.1757
Cell Significance Index: -93.3900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 85.3214
Cell Significance Index: -81.4600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 72.9467
Cell Significance Index: -89.9400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 26.2089
Cell Significance Index: -70.2100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 23.5324
Cell Significance Index: -92.8600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.2426
Cell Significance Index: -52.9600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.4686
Cell Significance Index: -25.1000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.8456
Cell Significance Index: 201.9100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 3.6408
Cell Significance Index: 39.5800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.3138
Cell Significance Index: 90.2000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 3.2242
Cell Significance Index: 112.0400 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.9245
Cell Significance Index: 23.3500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.8251
Cell Significance Index: 74.2900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 2.7666
Cell Significance Index: 57.9100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 2.6584
Cell Significance Index: 188.0100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.5686
Cell Significance Index: 120.7200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.5680
Cell Significance Index: 119.7300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.5058
Cell Significance Index: 308.1100 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.4640
Cell Significance Index: 318.3300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.3167
Cell Significance Index: 139.0800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.2864
Cell Significance Index: 412.1600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.1806
Cell Significance Index: 140.6800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.0878
Cell Significance Index: 155.6000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.0378
Cell Significance Index: 279.8500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.0369
Cell Significance Index: 1112.4000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.9502
Cell Significance Index: 862.2400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.7073
Cell Significance Index: 88.6900 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.5505
Cell Significance Index: 198.7700 - Cell Name: peg cell (CL4033014)
Fold Change: 1.4444
Cell Significance Index: 33.3700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.4257
Cell Significance Index: 168.1300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.2901
Cell Significance Index: 11.8800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.1965
Cell Significance Index: 118.3600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.1045
Cell Significance Index: 57.5300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.9788
Cell Significance Index: 11.1200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.9432
Cell Significance Index: 59.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.9112
Cell Significance Index: 155.6000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.8737
Cell Significance Index: 23.3300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8006
Cell Significance Index: 722.8800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.7647
Cell Significance Index: 21.9200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.7147
Cell Significance Index: 20.9900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.6992
Cell Significance Index: 19.5400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.6342
Cell Significance Index: 7.5600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5686
Cell Significance Index: 114.0700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4675
Cell Significance Index: 92.7900 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.3690
Cell Significance Index: 6.5200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3283
Cell Significance Index: 62.4700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3273
Cell Significance Index: 53.2400 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.2880
Cell Significance Index: 2.2200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.2484
Cell Significance Index: 182.1200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2288
Cell Significance Index: 82.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1961
Cell Significance Index: 8.8900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1404
Cell Significance Index: 4.9400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0827
Cell Significance Index: 57.1700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0589
Cell Significance Index: 0.9900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0247
Cell Significance Index: 18.7000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0053
Cell Significance Index: 9.9600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0072
Cell Significance Index: -5.3700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0169
Cell Significance Index: -31.2400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0308
Cell Significance Index: -47.4900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0344
Cell Significance Index: -3.5100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0480
Cell Significance Index: -29.9800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0641
Cell Significance Index: -87.1200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0777
Cell Significance Index: -49.3500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1044
Cell Significance Index: -58.8900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.1084
Cell Significance Index: -1.6300 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.1238
Cell Significance Index: -1.5900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1245
Cell Significance Index: -56.4900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1650
Cell Significance Index: -13.0700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1750
Cell Significance Index: -36.8600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1817
Cell Significance Index: -13.9400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2307
Cell Significance Index: -6.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2562
Cell Significance Index: -73.7200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3500
Cell Significance Index: -21.5100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3593
Cell Significance Index: -41.1600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3738
Cell Significance Index: -9.5500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.4482
Cell Significance Index: -7.6800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.4642
Cell Significance Index: -67.4700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.4950
Cell Significance Index: -57.6900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.5773
Cell Significance Index: -10.6700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.6281
Cell Significance Index: -8.5700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.6314
Cell Significance Index: -13.6800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.6387
Cell Significance Index: -72.9100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.6720
Cell Significance Index: -4.0600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7865
Cell Significance Index: -19.6600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.8077
Cell Significance Index: -25.8700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.8553
Cell Significance Index: -89.0600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.9195
Cell Significance Index: -51.6000 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -1.0695
Cell Significance Index: -9.1900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -1.1124
Cell Significance Index: -74.8000 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -1.3536
Cell Significance Index: -11.3700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.4138
Cell Significance Index: -86.6800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.4191
Cell Significance Index: -38.0300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -1.4197
Cell Significance Index: -20.9600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.4453
Cell Significance Index: -37.1500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 301754818
Symbol: VDAC2_HUMAN
Name: Voltage-dependent anion-selective channel protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7685033
Title: A mitochondrial porin cDNA predicts the existence of multiple human porins.
PubMed ID: 7685033
PubMed ID: 8420959
Title: Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.
PubMed ID: 8420959
PubMed ID: 10501981
Title: Revised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis.
PubMed ID: 10501981
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7539795
Title: Subcellular localization of human voltage-dependent anion channel isoforms.
PubMed ID: 7539795
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18088087
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25621951
Title: USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria.
PubMed ID: 25621951
DOI: 10.1038/ncb3097
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27641616
Title: TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.
PubMed ID: 27641616
DOI: 10.1038/srep33516
PubMed ID: 31015432
Title: Ceramides bind VDAC2 to trigger mitochondrial apoptosis.
PubMed ID: 31015432
PubMed ID: 38065946
Title: Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase.
PubMed ID: 38065946
Sequence Information:
- Length: 294
- Mass: 31567
- Checksum: F4EAE732E653637E
- Sequence:
MATHGQTCAR PMCIPPSYAD LGKAARDIFN KGFGFGLVKL DVKTKSCSGV EFSTSGSSNT DTGKVTGTLE TKYKWCEYGL TFTEKWNTDN TLGTEIAIED QICQGLKLTF DTTFSPNTGK KSGKIKSSYK RECINLGCDV DFDFAGPAIH GSAVFGYEGW LAGYQMTFDS AKSKLTRNNF AVGYRTGDFQ LHTNVNDGTE FGGSIYQKVC EDLDTSVNLA WTSGTNCTRF GIAAKYQLDP TASISAKVNN SSLIGVGYTQ TLRPGVKLTL SALVDGKSIN AGGHKVGLAL ELEA
Genular Protein ID: 419035041
Symbol: B4DKM5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 255
- Mass: 27479
- Checksum: 00718160955CE746
- Sequence:
MLVIPATQEA EEFSTSGSSN TDTGKVTGTL ETKYKWCEYG LTFTEKWNTD NTLGTEIAIE DQICQGLKLT FDTTFSPNTG KKSGKIKSSY KRECINLGCD VDFDFAGPAI HGSAVFGYEG WLAGYQMTFD SAKSKLTRNN FAVGYRTGDF QLHTNVNDGT EFGGSIYQKV CEDLDTSVNL AWTSGTNCTR FGIAAKYQLD PTASISAKVN NSSLIGVGYT QTLRPGVKLT LSALVDGKSI NAGGHKVGLA LELEA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.