Details for: WNT6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 27.7161
Cell Significance Index: -7.0300 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.7783
Cell Significance Index: 11.3000 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.7015
Cell Significance Index: 3.2400 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.5356
Cell Significance Index: 6.3300 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.4500
Cell Significance Index: 3.7800 - Cell Name: peridermal cell (CL0000078)
Fold Change: 0.3784
Cell Significance Index: 2.3600 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.2624
Cell Significance Index: 3.0500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2379
Cell Significance Index: 9.0100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2236
Cell Significance Index: 9.8900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1977
Cell Significance Index: 87.4200 - Cell Name: perivascular cell (CL4033054)
Fold Change: 0.1971
Cell Significance Index: 0.9100 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.1889
Cell Significance Index: 2.5900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1451
Cell Significance Index: 3.9500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.1254
Cell Significance Index: 2.6800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0782
Cell Significance Index: 14.1000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0757
Cell Significance Index: 1.9900 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.0523
Cell Significance Index: 0.6700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0516
Cell Significance Index: 2.7100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0395
Cell Significance Index: 5.0700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0278
Cell Significance Index: 1.9700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0217
Cell Significance Index: 2.6700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0216
Cell Significance Index: 11.8100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0183
Cell Significance Index: 0.8600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0157
Cell Significance Index: 2.1500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0155
Cell Significance Index: 3.0700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0090
Cell Significance Index: 0.1400 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0015
Cell Significance Index: 0.2000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0003
Cell Significance Index: 0.2300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0002
Cell Significance Index: -0.3500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0064
Cell Significance Index: -9.8400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0069
Cell Significance Index: -5.1000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0069
Cell Significance Index: -9.4000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0070
Cell Significance Index: -4.4500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0078
Cell Significance Index: -5.7800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0091
Cell Significance Index: -1.8300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0093
Cell Significance Index: -2.6900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0097
Cell Significance Index: -4.4300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0112
Cell Significance Index: -6.3300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0139
Cell Significance Index: -4.9800 - Cell Name: muscle cell (CL0000187)
Fold Change: -0.0199
Cell Significance Index: -0.1900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0239
Cell Significance Index: -1.2100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0271
Cell Significance Index: -3.9400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0271
Cell Significance Index: -1.1100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0283
Cell Significance Index: -0.7900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0323
Cell Significance Index: -3.8200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0397
Cell Significance Index: -8.3700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0402
Cell Significance Index: -6.8600 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.0421
Cell Significance Index: -0.5900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0458
Cell Significance Index: -4.7700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0491
Cell Significance Index: -1.3100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0502
Cell Significance Index: -3.1700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0521
Cell Significance Index: -1.3400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0524
Cell Significance Index: -5.3600 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.0543
Cell Significance Index: -0.6600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0563
Cell Significance Index: -6.4600 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: -0.0576
Cell Significance Index: -0.2800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0695
Cell Significance Index: -5.1800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0708
Cell Significance Index: -4.7600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0737
Cell Significance Index: -5.6600 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0872
Cell Significance Index: -3.7900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.0912
Cell Significance Index: -2.2100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0958
Cell Significance Index: -5.8900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0966
Cell Significance Index: -2.7700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1019
Cell Significance Index: -1.3900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1053
Cell Significance Index: -5.9100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1093
Cell Significance Index: -5.6800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1096
Cell Significance Index: -3.8400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1137
Cell Significance Index: -2.3800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1163
Cell Significance Index: -1.6700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1216
Cell Significance Index: -5.6700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1258
Cell Significance Index: -5.7000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1331
Cell Significance Index: -2.9200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1331
Cell Significance Index: -3.5600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1401
Cell Significance Index: -4.8700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1409
Cell Significance Index: -4.0200 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.1456
Cell Significance Index: -2.3100 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: -0.1508
Cell Significance Index: -1.6900 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1528
Cell Significance Index: -3.8100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1532
Cell Significance Index: -5.0200 - Cell Name: megakaryocyte (CL0000556)
Fold Change: -0.1599
Cell Significance Index: -2.5900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1627
Cell Significance Index: -4.3600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1652
Cell Significance Index: -5.2600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1708
Cell Significance Index: -5.0300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1747
Cell Significance Index: -1.9800 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.1786
Cell Significance Index: -2.5400 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: -0.1852
Cell Significance Index: -1.1100 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -0.1873
Cell Significance Index: -2.5900 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1880
Cell Significance Index: -4.6900 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.1909
Cell Significance Index: -2.4700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1917
Cell Significance Index: -5.6300 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.1988
Cell Significance Index: -1.6900 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.2006
Cell Significance Index: -5.0100 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.2062
Cell Significance Index: -2.1900 - Cell Name: mural cell (CL0008034)
Fold Change: -0.2111
Cell Significance Index: -2.5700 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.2133
Cell Significance Index: -4.3400 - Cell Name: Schwann cell (CL0002573)
Fold Change: -0.2135
Cell Significance Index: -2.3900 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.2169
Cell Significance Index: -2.0600 - Cell Name: medium spiny neuron (CL1001474)
Fold Change: -0.2171
Cell Significance Index: -2.9300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2209
Cell Significance Index: -8.1100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.2251
Cell Significance Index: -3.9800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3928823601
Symbol: WNT6_HUMAN
Name: Protein Wnt-6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11350055
Title: WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly co-expressed in SW480 cells.
PubMed ID: 11350055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10343101
Title: Partial cloning and assignment of WNT6 to human chromosome band 2q35 by in situ hybridization.
PubMed ID: 10343101
DOI: 10.1159/000015212
PubMed ID: 22370641
Title: WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells.
PubMed ID: 22370641
DOI: 10.1038/onc.2012.40
Sequence Information:
- Length: 365
- Mass: 39721
- Checksum: 928DE396C58E295B
- Sequence:
MLPPLPSRLG LLLLLLLCPA HVGGLWWAVG SPLVMDPTSI CRKARRLAGR QAELCQAEPE VVAELARGAR LGVRECQFQF RFRRWNCSSH SKAFGRILQQ DIRETAFVFA ITAAGASHAV TQACSMGELL QCGCQAPRGR APPRPSGLPG TPGPPGPAGS PEGSAAWEWG GCGDDVDFGD EKSRLFMDAR HKRGRGDIRA LVQLHNNEAG RLAVRSHTRT ECKCHGLSGS CALRTCWQKL PPFREVGARL LERFHGASRV MGTNDGKALL PAVRTLKPPG RADLLYAADS PDFCAPNRRT GSPGTRGRAC NSSAPDLSGC DLLCCGRGHR QESVQLEENC LCRFHWCCVV QCHRCRVRKE LSLCL
Genular Protein ID: 1366991155
Symbol: Q8N2E5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16303743
Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
PubMed ID: 16303743
Sequence Information:
- Length: 365
- Mass: 39850
- Checksum: 865EA878D1C5C8E5
- Sequence:
MLPPLPSRLG LLLLLLLCPA HVGGLWWAVG SPLVMDPTSI CRKARRLAGR QAELCQAEPE VVAELARGAR LGVRECQFQF RFRRWNCSSH SKAFGRILQQ DIRETAFVFA ITAAGASHAV TQACSMGELL QCGCQAPRWR APPRPSGLPG TPGPPGPAGS PEGSAAWEWG GCGDDVDFGD EKSRLFMDAR HKRGRGDIRA LVQLHNNEAG RLAVRSHTRT ECKCHGLSGS CALRTCWQKL PPFREVGARL LERFHGASRV MGTNDGKALL PAVRTLKPPG RADLLYAADS PDFCAPNRRT GSPGTRGRAC NSSAPDLSGC DLLCCGRGHR QESVQLEENC LCRFHWCCVV QCHRCRVRKE LSLCL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.