Details for: CSDE1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 730.2056
Cell Significance Index: -113.5800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 443.5361
Cell Significance Index: -112.5000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 331.7534
Cell Significance Index: -136.6700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 280.7957
Cell Significance Index: -132.5700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 274.3090
Cell Significance Index: -111.4400 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 244.8360
Cell Significance Index: -125.9400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 197.8474
Cell Significance Index: -132.7600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 118.3879
Cell Significance Index: -113.0300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 101.2607
Cell Significance Index: -124.8500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 40.9129
Cell Significance Index: -109.6000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 33.4360
Cell Significance Index: -131.9400 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 29.2011
Cell Significance Index: -89.6900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 19.3687
Cell Significance Index: -42.3900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 3.9398
Cell Significance Index: 272.4600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.7732
Cell Significance Index: 340.9900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.7586
Cell Significance Index: 128.6200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.6698
Cell Significance Index: 481.2900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.6560
Cell Significance Index: 70.9200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.6337
Cell Significance Index: 361.6800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.6112
Cell Significance Index: 67.1200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.2879
Cell Significance Index: 60.1600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.1746
Cell Significance Index: 1187.5800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.1529
Cell Significance Index: 112.1400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.0478
Cell Significance Index: 96.2500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.8360
Cell Significance Index: 811.7600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.7818
Cell Significance Index: 357.4200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.6384
Cell Significance Index: 44.6000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.5956
Cell Significance Index: 55.4500 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.5639
Cell Significance Index: 202.0500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.4732
Cell Significance Index: 109.8000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4700
Cell Significance Index: 291.7300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.3800
Cell Significance Index: 97.6000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.3339
Cell Significance Index: 227.7700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.3330
Cell Significance Index: 86.0000 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.2962
Cell Significance Index: 166.1700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.0981
Cell Significance Index: 129.5100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0886
Cell Significance Index: 982.8900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.0792
Cell Significance Index: 30.9400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.0612
Cell Significance Index: 380.6300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.8563
Cell Significance Index: 44.9600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8037
Cell Significance Index: 23.1600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7402
Cell Significance Index: 73.2200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.6849
Cell Significance Index: 35.5800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6818
Cell Significance Index: 40.9300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.6300
Cell Significance Index: 48.3500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6284
Cell Significance Index: 102.2100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6163
Cell Significance Index: 426.2700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5876
Cell Significance Index: 12.3000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1077
Cell Significance Index: 202.7400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0538
Cell Significance Index: 10.2500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0437
Cell Significance Index: 32.0200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.0344
Cell Significance Index: 0.6300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0183
Cell Significance Index: 33.7700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0119
Cell Significance Index: 7.5300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0077
Cell Significance Index: 11.9000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0034
Cell Significance Index: -0.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0051
Cell Significance Index: -3.8800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0182
Cell Significance Index: -0.3100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0302
Cell Significance Index: -18.8800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0333
Cell Significance Index: -1.1700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0366
Cell Significance Index: -16.6300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0408
Cell Significance Index: -55.5100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0501
Cell Significance Index: -37.0900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1111
Cell Significance Index: -11.3500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1662
Cell Significance Index: -93.7200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1961
Cell Significance Index: -11.0100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2593
Cell Significance Index: -54.6200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3061
Cell Significance Index: -8.9900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.3512
Cell Significance Index: -8.5700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3779
Cell Significance Index: -23.8200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3892
Cell Significance Index: -111.9800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4159
Cell Significance Index: -3.8300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.4292
Cell Significance Index: -62.3900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4378
Cell Significance Index: -49.9700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.5296
Cell Significance Index: -35.6100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.5632
Cell Significance Index: -64.5200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5939
Cell Significance Index: -69.2100 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.6399
Cell Significance Index: -7.2700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.7199
Cell Significance Index: -20.1200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.7542
Cell Significance Index: -10.2900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.0141
Cell Significance Index: -80.3200 - Cell Name: peg cell (CL4033014)
Fold Change: -1.1120
Cell Significance Index: -25.6900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.1133
Cell Significance Index: -115.9300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -1.1468
Cell Significance Index: -20.2700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -1.1534
Cell Significance Index: -52.2800 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -1.2105
Cell Significance Index: -13.1600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.3094
Cell Significance Index: -33.4500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.3224
Cell Significance Index: -28.6500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.4225
Cell Significance Index: -62.9200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.5662
Cell Significance Index: -39.1500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.6285
Cell Significance Index: -52.1600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.6804
Cell Significance Index: -44.9500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -1.7569
Cell Significance Index: -66.5300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.7769
Cell Significance Index: -108.9400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.8666
Cell Significance Index: -50.0200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -2.0488
Cell Significance Index: -35.1100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -2.1991
Cell Significance Index: -42.9200 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -2.2290
Cell Significance Index: -33.4000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -2.5762
Cell Significance Index: -15.5700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -2.6525
Cell Significance Index: -39.1600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 70714128
Symbol: CSDE1_HUMAN
Name: N-ras upstream gene protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2052355
Title: Organization of the human N-ras locus: characterization of a gene located immediately upstream of N-ras.
PubMed ID: 2052355
PubMed ID: 10931946
Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
PubMed ID: 10931946
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8439573
Title: Exon skipping in the expression of the gene immediately upstream of N-ras (unr/NRU).
PubMed ID: 8439573
PubMed ID: 10049359
Title: unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA.
PubMed ID: 10049359
DOI: 10.1101/gad.13.4.437
PubMed ID: 11051545
Title: A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex.
PubMed ID: 11051545
PubMed ID: 15314026
Title: UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.
PubMed ID: 15314026
DOI: 10.1101/gad.1219104
PubMed ID: 16356927
Title: The autoregulatory translational control element of poly(A)-binding protein mRNA forms a heteromeric ribonucleoprotein complex.
PubMed ID: 16356927
DOI: 10.1093/nar/gki1014
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 27342281
Title: The DDX6-4E-T interaction mediates translational repression and P-body assembly.
PubMed ID: 27342281
DOI: 10.1093/nar/gkw565
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29395067
Title: High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
PubMed ID: 29395067
PubMed ID: 32354837
Title: 4E-T-bound mRNAs are stored in a silenced and deadenylated form.
PubMed ID: 32354837
PubMed ID: 20213426
Title: The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein.
PubMed ID: 20213426
Sequence Information:
- Length: 798
- Mass: 88885
- Checksum: 2BD0B32F33D454DA
- Sequence:
MSFDPNLLHN NGHNGYPNGT SAALRETGVI EKLLTSYGFI QCSERQARLF FHCSQYNGNL QDLKVGDDVE FEVSSDRRTG KPIAVKLVKI KQEILPEERM NGQVVCAVPH NLESKSPAAP GQSPTGSVCY ERNGEVFYLT YTPEDVEGNV QLETGDKINF VIDNNKHTGA VSARNIMLLK KKQARCQGVV CAMKEAFGFI ERGDVVKEIF FHYSEFKGDL ETLQPGDDVE FTIKDRNGKE VATDVRLLPQ GTVIFEDISI EHFEGTVTKV IPKVPSKNQN DPLPGRIKVD FVIPKELPFG DKDTKSKVTL LEGDHVRFNI STDRRDKLER ATNIEVLSNT FQFTNEAREM GVIAAMRDGF GFIKCVDRDV RMFFHFSEIL DGNQLHIADE VEFTVVPDML SAQRNHAIRI KKLPKGTVSF HSHSDHRFLG TVEKEATFSN PKTTSPNKGK EKEAEDGIIA YDDCGVKLTI AFQAKDVEGS TSPQIGDKVE FSISDKQRPG QQVATCVRLL GRNSNSKRLL GYVATLKDNF GFIETANHDK EIFFHYSEFS GDVDSLELGD MVEYSLSKGK GNKVSAEKVN KTHSVNGITE EADPTIYSGK VIRPLRSVDP TQTEYQGMIE IVEEGDMKGE VYPFGIVGMA NKGDCLQKGE SVKFQLCVLG QNAQTMAYNI TPLRRATVEC VKDQFGFINY EVGDSKKLFF HVKEVQDGIE LQAGDEVEFS VILNQRTGKC SACNVWRVCE GPKAVAAPRP DRLVNRLKNI TLDDASAPRL MVLRQPRGPD NSMGFGAERK IRQAGVID
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.