Details for: SLBP

Gene ID: 7884

Symbol: SLBP

Ensembl ID: ENSG00000163950

Description: stem-loop histone mRNA binding protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 142.4047
    Cell Significance Index: -36.1200
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 134.6554
    Cell Significance Index: -20.9500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.7603
    Cell Significance Index: -42.8500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 90.1892
    Cell Significance Index: -36.6400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 80.3872
    Cell Significance Index: -41.3500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 63.8727
    Cell Significance Index: -42.8600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.4763
    Cell Significance Index: -36.7400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.2623
    Cell Significance Index: -38.5500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.7396
    Cell Significance Index: -28.7700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.6030
    Cell Significance Index: -41.8400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.6246
    Cell Significance Index: -26.4900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 4.7468
    Cell Significance Index: 76.1600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.6880
    Cell Significance Index: -10.2600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 2.8411
    Cell Significance Index: 331.1000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.4897
    Cell Significance Index: 293.6100
  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.4183
    Cell Significance Index: 18.2600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.5034
    Cell Significance Index: 40.9200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.1027
    Cell Significance Index: 29.0000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0833
    Cell Significance Index: 69.8900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9786
    Cell Significance Index: 534.4200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9579
    Cell Significance Index: 117.7800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8412
    Cell Significance Index: 39.5400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8170
    Cell Significance Index: 112.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.7804
    Cell Significance Index: 27.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.7668
    Cell Significance Index: 22.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.7243
    Cell Significance Index: 19.3400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.7184
    Cell Significance Index: 7.8100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6450
    Cell Significance Index: 285.1900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6130
    Cell Significance Index: 110.5000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6053
    Cell Significance Index: 121.4300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5910
    Cell Significance Index: 40.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5737
    Cell Significance Index: 113.8600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.5523
    Cell Significance Index: 11.5600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5473
    Cell Significance Index: 494.1900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4759
    Cell Significance Index: 61.0100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4607
    Cell Significance Index: 32.5800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4105
    Cell Significance Index: 10.9800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3530
    Cell Significance Index: 10.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2981
    Cell Significance Index: 38.5100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2687
    Cell Significance Index: 14.1100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2497
    Cell Significance Index: 5.4100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2316
    Cell Significance Index: 83.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1774
    Cell Significance Index: 8.2700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1699
    Cell Significance Index: 117.5300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1684
    Cell Significance Index: 8.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1681
    Cell Significance Index: 7.6200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1510
    Cell Significance Index: 25.7900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1157
    Cell Significance Index: 22.0300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1093
    Cell Significance Index: 8.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1013
    Cell Significance Index: 2.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0885
    Cell Significance Index: 8.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0564
    Cell Significance Index: 106.1600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0287
    Cell Significance Index: 0.4800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0173
    Cell Significance Index: 26.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0095
    Cell Significance Index: 17.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0016
    Cell Significance Index: -2.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0071
    Cell Significance Index: -5.2400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0113
    Cell Significance Index: -8.5800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0131
    Cell Significance Index: -8.1600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0145
    Cell Significance Index: -10.6700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0162
    Cell Significance Index: -10.3000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0358
    Cell Significance Index: -3.6600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0514
    Cell Significance Index: -7.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0514
    Cell Significance Index: -29.0000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0560
    Cell Significance Index: -1.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0586
    Cell Significance Index: -26.6100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0740
    Cell Significance Index: -2.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0944
    Cell Significance Index: -19.8800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1002
    Cell Significance Index: -28.8300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1018
    Cell Significance Index: -0.8300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1281
    Cell Significance Index: -14.6800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1312
    Cell Significance Index: -3.5200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1579
    Cell Significance Index: -18.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1776
    Cell Significance Index: -6.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1785
    Cell Significance Index: -10.9700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2029
    Cell Significance Index: -13.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2850
    Cell Significance Index: -15.9900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2905
    Cell Significance Index: -8.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3021
    Cell Significance Index: -19.0400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3083
    Cell Significance Index: -23.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3611
    Cell Significance Index: -37.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4099
    Cell Significance Index: -32.4700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4244
    Cell Significance Index: -5.7900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4421
    Cell Significance Index: -9.4200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4781
    Cell Significance Index: -11.9500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5074
    Cell Significance Index: -14.4800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5098
    Cell Significance Index: -3.0800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5625
    Cell Significance Index: -5.1800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5736
    Cell Significance Index: -25.3700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6345
    Cell Significance Index: -18.6900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.6449
    Cell Significance Index: -11.9200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6506
    Cell Significance Index: -33.8900
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.6635
    Cell Significance Index: -9.3000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.6823
    Cell Significance Index: -9.5700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6839
    Cell Significance Index: -15.8000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7046
    Cell Significance Index: -26.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7058
    Cell Significance Index: -43.2700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7318
    Cell Significance Index: -36.9800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7516
    Cell Significance Index: -12.8800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7598
    Cell Significance Index: -19.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **MRNA Binding Protein:** SLBP is a stem-loop histone mRNA binding protein that recognizes and binds to specific stem-loop structures within histone mRNAs. 2. **Histone mRNA Processing:** SLBP participates in the processing of histone mRNAs, ensuring their translation and proper incorporation into chromatin. 3. **Regulation of Gene Expression:** By controlling histone mRNA processing, SLBP influences gene expression, allowing for precise regulation of chromatin structure and function. 4. **Cell Type-Specific Expression:** SLBP is expressed in various cell types, including early promyelocytes, oogonial cells, and mature T cells, indicating its importance in different cellular contexts. **Pathways and Functions:** 1. **Cap-Dependent Translational Initiation:** SLBP is involved in the regulation of cap-dependent translational initiation, ensuring the accurate translation of histone mRNAs. 2. **Histone Pre-mRNA Processing Complex:** SLBP is a key component of the histone pre-mRNA processing complex, facilitating the precise processing of histone mRNAs. 3. **RNA Binding:** SLBP recognizes and binds to specific stem-loop structures within histone mRNAs, regulating their processing and translation. 4. **Metabolism of RNA:** SLBP influences the metabolism of RNA, ensuring the proper processing and translation of histone mRNAs. **Clinical Significance:** 1. **Genetic Disorders:** Mutations in the SLBP gene have been linked to genetic disorders, such as Aplastic Anemia, highlighting its importance in maintaining genome stability. 2. **Cancer:** Alterations in SLBP expression have been observed in various cancers, suggesting its role in cancer development and progression. 3. **Immunological Disorders:** SLBP is expressed in mature T cells, and alterations in its expression have been linked to immunological disorders, such as autoimmune diseases. 4. **Regulation of Gene Expression:** SLBP's role in regulating gene expression makes it a valuable target for the development of novel therapeutic strategies for diseases characterized by dysregulated gene expression. In conclusion, the SLBP gene plays a crucial role in the regulation of histone mRNA processing and gene expression, with implications for genome stability, cellular function, and disease development. Further research into the SLBP gene and its functions is necessary to fully appreciate its significance in human health and disease.

Genular Protein ID: 4133971025

Symbol: SLBP_HUMAN

Name: Histone RNA hairpin-binding protein

UniProtKB Accession Codes:

Q14493 B3KRJ5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 8 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1338771

Title: Expressed genes, Alu repeats and polymorphisms in cosmids sequenced from chromosome 4p16.3.

PubMed ID: 1338771

DOI: 10.1038/ng0892-348

PubMed ID: 8957003

Title: The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing.

PubMed ID: 8957003

DOI: 10.1101/gad.10.23.3028

PubMed ID: 9049306

Title: The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein.

PubMed ID: 9049306

DOI: 10.1093/emboj/16.4.769

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11782445

Title: A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing.

PubMed ID: 11782445

DOI: 10.1101/gad.932302

PubMed ID: 12588979

Title: Phosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phase.

PubMed ID: 12588979

DOI: 10.1128/mcb.23.5.1590-1601.2003

PubMed ID: 15829567

Title: Nuclear import of the stem-loop binding protein and localization during the cell cycle.

PubMed ID: 15829567

DOI: 10.1091/mbc.e04-11-1023

PubMed ID: 16086026

Title: Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.

PubMed ID: 16086026

DOI: 10.1038/nsmb972

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16912046

Title: Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA.

PubMed ID: 16912046

DOI: 10.1074/jbc.m602947200

PubMed ID: 18172165

Title: Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

PubMed ID: 18172165

DOI: 10.1101/gad.1622708

PubMed ID: 18025107

Title: SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.

PubMed ID: 18025107

DOI: 10.1128/mcb.01500-07

PubMed ID: 18490441

Title: Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase.

PubMed ID: 18490441

DOI: 10.1128/mcb.01416-07

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19155325

Title: Knockdown of SLBP results in nuclear retention of histone mRNA.

PubMed ID: 19155325

DOI: 10.1261/rna.1205409

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28118078

Title: FEM1 proteins are ancient regulators of SLBP degradation.

PubMed ID: 28118078

DOI: 10.1080/15384101.2017.1284715

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 22439849

Title: Interaction of the histone mRNA hairpin with stem-loop binding protein (SLBP) and regulation of the SLBP-RNA complex by phosphorylation and proline isomerization.

PubMed ID: 22439849

DOI: 10.1021/bi2018255

Sequence Information:

  • Length: 270
  • Mass: 31286
  • Checksum: 4E84E502393D1BF7
  • Sequence:
    • MACRPRSPPR HQSRCDGDAS PPSPARWSLG RKRRADGRRW RPEDAEEAEH RGAERRPESF 
TTPEGPKPRS RCSDWASAVE EDEMRTRVNK EMARYKRKLL INDFGRERKS SSGSSDSKES 
MSTVPADFET DESVLMRRQK QINYGKNTIA YDRYIKEVPR HLRQPGIHPK TPNKFKKYSR 
RSWDQQIKLW KVALHFWDPP AEEGCDLQEI HPVDLESAES SSEPQTSSQD DFDVYSGTPT 
KVRHMDSQVE DEFDLEACLT EPLRDFSAMS

Genular Protein ID: 3520619597

Symbol: B3KSC5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KSC5

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 6 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMR 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 187
  • Mass: 21808
  • Checksum: 0925EA048AC9AC32
  • Sequence:
    • MRTRVNKEMA RYKRKLLIND FGRERKSSSG SSDSKESMST VPADFETDES VLMRRQKQIN 
YGKNTIAYDR YIKEVPRHLR QPGIHPKTPN KFKKYSRRSW DQQIKLWKVA LHFWDPPAEE 
GCDLQEIHPV DLESAESSSE PQTSSQDDFD VYSGTPTKVR HMDSQVEDEF DLEACLTEPL 
RDFSAMS

Genular Protein ID: 3307770022

Symbol: B3KST9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KST9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 3 SAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 270
  • Mass: 31285
  • Checksum: 448442B4948B1BF7
  • Sequence:
    • MACRPRSPPR HQSRCDGDAS PPSPARWSLG RKRRADGRRW RPEDAEEAEH RGAERRPESF 
TTPEGPKPRS RCSDWASAVE EDEMRTRVNK EMARYKRKLL INDFGRERKS SSGSSDSKES 
MSTVPADFET DKSVLMRRQK QINYGKNTIA YDRYIKEVPR HLRQPGIHPK TPNKFKKYSR 
RSWDQQIKLW KVALHFWDPP AEEGCDLQEI HPVDLESAES SSEPQTSSQD DFDVYSGTPT 
KVRHMDSQVE DEFDLEACLT EPLRDFSAMS

Genular Protein ID: 947447551

Symbol: B4DUW7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DUW7

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMR 1

Sequence Information:

  • Length: 235
  • Mass: 27246
  • Checksum: C29D21012D8A4A61
  • Sequence:
    • MACRPRSPPR HQSRCDGDAS PPSPARWSLG RKRRADGRRW RPEDAEEAEH RGAERRPERY 
KRKLLINDFG RERKSSSGSS DSKESMSTVP ADFETDESVL MRRQKQINYG KNTIAYGRYI 
KEVPRHLRQP GIHPKTPNKF KKYSRRSWDQ QIKLWKVALH FWDPPAEEGC DLQEIHPVDL 
ESAESSSEPQ TSSQDDFDVY SGTPTKVRHM DSQVEDEFDL EACLTEPLRD FSAMS

Genular Protein ID: 2281648231

Symbol: E7EUV9_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EUV9

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 235
  • Mass: 27304
  • Checksum: F19D21012E8A4B28
  • Sequence:
    • MACRPRSPPR HQSRCDGDAS PPSPARWSLG RKRRADGRRW RPEDAEEAEH RGAERRPERY 
KRKLLINDFG RERKSSSGSS DSKESMSTVP ADFETDESVL MRRQKQINYG KNTIAYDRYI 
KEVPRHLRQP GIHPKTPNKF KKYSRRSWDQ QIKLWKVALH FWDPPAEEGC DLQEIHPVDL 
ESAESSSEPQ TSSQDDFDVY SGTPTKVRHM DSQVEDEFDL EACLTEPLRD FSAMS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.