Details for: AIMP2

Gene ID: 7965

Symbol: AIMP2

Ensembl ID: ENSG00000106305

Description: aminoacyl tRNA synthetase complex interacting multifunctional protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 132.6302
    Cell Significance Index: -20.6300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 75.5391
    Cell Significance Index: -19.1600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 62.7507
    Cell Significance Index: -25.8500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 52.7088
    Cell Significance Index: -24.8900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 49.4761
    Cell Significance Index: -20.1000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 46.9298
    Cell Significance Index: -24.1400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.2832
    Cell Significance Index: -20.3200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.9098
    Cell Significance Index: -23.3200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.5853
    Cell Significance Index: -20.3200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.1124
    Cell Significance Index: -24.1200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.9265
    Cell Significance Index: -12.0600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.4908
    Cell Significance Index: -7.6400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.5787
    Cell Significance Index: 178.3300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.7178
    Cell Significance Index: 103.1300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2555
    Cell Significance Index: 17.1300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1955
    Cell Significance Index: 118.2700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0112
    Cell Significance Index: 913.0100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.9160
    Cell Significance Index: 23.4000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7446
    Cell Significance Index: 121.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.6744
    Cell Significance Index: 78.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5400
    Cell Significance Index: 28.0500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5008
    Cell Significance Index: 10.8500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4670
    Cell Significance Index: 12.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4473
    Cell Significance Index: 88.7600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4220
    Cell Significance Index: 27.2300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3880
    Cell Significance Index: 211.8700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3572
    Cell Significance Index: 27.4100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3381
    Cell Significance Index: 39.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3349
    Cell Significance Index: 60.3700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3163
    Cell Significance Index: 22.3700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3024
    Cell Significance Index: 133.6900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2934
    Cell Significance Index: 7.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2593
    Cell Significance Index: 52.0100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2566
    Cell Significance Index: 31.5500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.2421
    Cell Significance Index: 7.7600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2050
    Cell Significance Index: 39.0100
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.1988
    Cell Significance Index: 3.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1877
    Cell Significance Index: 25.7700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1840
    Cell Significance Index: 8.5800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1633
    Cell Significance Index: 10.2900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1604
    Cell Significance Index: 20.7200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.1518
    Cell Significance Index: 1.6500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1371
    Cell Significance Index: 2.9200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1188
    Cell Significance Index: 3.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1185
    Cell Significance Index: 8.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1180
    Cell Significance Index: 2.9500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1066
    Cell Significance Index: 13.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1015
    Cell Significance Index: 2.6100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0965
    Cell Significance Index: 34.6000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0814
    Cell Significance Index: 1.2200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.0723
    Cell Significance Index: 1.7700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0667
    Cell Significance Index: 4.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0517
    Cell Significance Index: 35.7300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0466
    Cell Significance Index: 1.2300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0460
    Cell Significance Index: 1.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0449
    Cell Significance Index: 2.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0258
    Cell Significance Index: 0.7200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0207
    Cell Significance Index: 0.5600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0200
    Cell Significance Index: 0.3000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0117
    Cell Significance Index: 0.4100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0103
    Cell Significance Index: 0.2700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0037
    Cell Significance Index: 6.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0007
    Cell Significance Index: 0.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0002
    Cell Significance Index: 0.2800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0000
    Cell Significance Index: 0.0900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0007
    Cell Significance Index: -1.0200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0039
    Cell Significance Index: -2.9700
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0112
    Cell Significance Index: -0.1800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0127
    Cell Significance Index: -1.3000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0180
    Cell Significance Index: -3.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0213
    Cell Significance Index: -9.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0226
    Cell Significance Index: -14.3400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0268
    Cell Significance Index: -0.5600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0274
    Cell Significance Index: -0.2300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0275
    Cell Significance Index: -20.3900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0395
    Cell Significance Index: -22.2600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0454
    Cell Significance Index: -28.3200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0574
    Cell Significance Index: -16.5100
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.0642
    Cell Significance Index: -0.4900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0707
    Cell Significance Index: -3.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0816
    Cell Significance Index: -11.8600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0998
    Cell Significance Index: -5.2000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1064
    Cell Significance Index: -1.7800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1190
    Cell Significance Index: -2.0400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1192
    Cell Significance Index: -13.6600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1309
    Cell Significance Index: -1.3600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1349
    Cell Significance Index: -28.4100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1705
    Cell Significance Index: -1.0300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1822
    Cell Significance Index: -2.0700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2113
    Cell Significance Index: -22.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2162
    Cell Significance Index: -17.1200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2403
    Cell Significance Index: -10.8900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2429
    Cell Significance Index: -12.7600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2469
    Cell Significance Index: -16.6000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2541
    Cell Significance Index: -2.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2756
    Cell Significance Index: -12.1900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2781
    Cell Significance Index: -5.1400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.2918
    Cell Significance Index: -2.3300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3008
    Cell Significance Index: -6.9500
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.3153
    Cell Significance Index: -4.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AIMP2 is a multifunctional protein that interacts with aminoacyl-tRNA synthetases, which are essential for the accurate translation of mRNA into proteins. AIMP2 has been shown to modulate the activity of these synthetases, influencing the fidelity of protein synthesis. Additionally, AIMP2 has been implicated in the regulation of protein ubiquitination, a process that targets proteins for degradation. **Pathways and Functions:** AIMP2 is involved in several key pathways, including: 1. **Aminoacyl-trna synthetase multienzyme complex**: AIMP2 interacts with aminoacyl-tRNA synthetases, which are essential for the accurate translation of mRNA into proteins. 2. **Apoptotic process**: AIMP2 has been shown to regulate apoptosis, a process of programmed cell death, by modulating the activity of pro-apoptotic and anti-apoptotic proteins. 3. **Cytosol and nucleus**: AIMP2 is localized to both the cytosol and nucleus, where it interacts with proteins involved in protein synthesis, apoptosis, and cellular differentiation. 4. **Metabolism of amino acids and derivatives**: AIMP2 is involved in the regulation of amino acid metabolism, including the synthesis and degradation of amino acids. 5. **Protein-containing complex assembly**: AIMP2 interacts with proteins involved in the assembly of protein-containing complexes, such as ribosomes and protein ubiquitination complexes. **Functions:** AIMP2 has several functions, including: 1. **Regulation of protein synthesis**: AIMP2 modulates the activity of aminoacyl-tRNA synthetases, influencing the fidelity of protein synthesis. 2. **Regulation of apoptosis**: AIMP2 regulates apoptosis by modulating the activity of pro-apoptotic and anti-apoptotic proteins. 3. **Cellular differentiation**: AIMP2 is involved in the regulation of cellular differentiation, including the differentiation of type II pneumocytes and primordial germ cells. 4. **Protein ubiquitination**: AIMP2 interacts with proteins involved in protein ubiquitination, regulating the degradation of proteins. **Clinical Significance:** AIMP2 has significant clinical implications, including: 1. **Cancer**: AIMP2 is overexpressed in several types of cancer, including breast, lung, and colon cancer, suggesting its potential as a prognostic marker. 2. **Neurodegenerative diseases**: AIMP2 has been implicated in neurodegenerative diseases, including Alzheimer's and Parkinson's disease, suggesting its potential as a therapeutic target. 3. **Apoptosis**: AIMP2 regulates apoptosis, which is essential for the elimination of damaged or dysfunctional cells, suggesting its potential as a therapeutic target for cancer and neurodegenerative diseases. In conclusion, AIMP2 is a multifaceted gene involved in various cellular processes, including protein synthesis, apoptosis, and cellular differentiation. Its significant expression in different cell types and its clinical implications make it an important target for further research and potential therapeutic applications.

Genular Protein ID: 3669904268

Symbol: AIMP2_HUMAN

Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

UniProtKB Accession Codes:

Q13155 F8W950 Q75MR1 Q96CZ5 Q9P1L2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8666379

Title: Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene.

PubMed ID: 8666379

DOI: 10.1006/geno.1995.9997

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24312579

Title: Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex.

PubMed ID: 24312579

DOI: 10.1371/journal.pone.0081734

PubMed ID: 9878398

Title: Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein.

PubMed ID: 9878398

DOI: 10.1006/jmbi.1998.2316

PubMed ID: 12819782

Title: Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation.

PubMed ID: 12819782

DOI: 10.1038/ng1182

PubMed ID: 15220430

Title: Cellular distribution of Lysyl-tRNA synthetase and its interaction with Gag during human immunodeficiency virus type 1 assembly.

PubMed ID: 15220430

DOI: 10.1128/jvi.78.14.7553-7564.2004

PubMed ID: 16135753

Title: Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

PubMed ID: 16135753

DOI: 10.1523/jneurosci.2172-05.2005

PubMed ID: 18029264

Title: Lysyl-tRNA synthetase interacts with EF1alpha, aspartyl-tRNA synthetase and p38 in vitro.

PubMed ID: 18029264

DOI: 10.1016/j.bbrc.2007.11.028

PubMed ID: 18695251

Title: AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53.

PubMed ID: 18695251

DOI: 10.1073/pnas.0800297105

PubMed ID: 19131329

Title: Dissection of the structural organization of the aminoacyl-tRNA synthetase complex.

PubMed ID: 19131329

DOI: 10.1074/jbc.m809636200

PubMed ID: 19289464

Title: Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.

PubMed ID: 19289464

DOI: 10.1074/jbc.m900480200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 23159739

Title: Structural switch of lysyl-tRNA synthetase between translation and transcription.

PubMed ID: 23159739

DOI: 10.1016/j.molcel.2012.10.010

PubMed ID: 26074468

Title: Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.

PubMed ID: 26074468

DOI: 10.1016/j.chembiol.2015.05.007

PubMed ID: 26472928

Title: Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains.

PubMed ID: 26472928

DOI: 10.1074/jbc.m115.690867

PubMed ID: 29215095

Title: Homozygosity for a nonsense variant in AIMP2 is associated with a progressive neurodevelopmental disorder with microcephaly, seizures, and spastic quadriparesis.

PubMed ID: 29215095

DOI: 10.1038/s10038-017-0363-1

Sequence Information:

  • Length: 320
  • Mass: 35349
  • Checksum: F253726B63C12BAB
  • Sequence:
    • MPMYQVKPYH GGGAPLRVEL PTCMYRLPNV HGRSYGPAPG AGHVQEESNL SLQALESRQD 
DILKRLYELK AAVDGLSKMI QTPDADLDVT NIIQADEPTT LTTNALDLNS VLGKDYGALK 
DIVINANPAS PPLSLLVLHR LLCEHFRVLS TVHTHSSVKS VPENLLKCFG EQNKKQPRQD 
YQLGFTLIWK NVPKTQMKFS IQTMCPIEGE GNIARFLFSL FGQKHNAVNA TLIDSWVDIA 
IFQLKEGSSK EKAAVFRSMN SALGKSPWLA GNELTVADVV LWSVLQQIGG CSVTVPANVQ 
RWMRSCENLA PFNTALKLLK

Genular Protein ID: 3482054776

Symbol: A8MU58_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8MU58

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 4 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 242
  • Mass: 26760
  • Checksum: 4DFA64C55EAA29F0
  • Sequence:
    • MIQTPDADLD VTNIIQADEP TTLTTNALDL NSVLGKDYGA LKDIVINANP ASPPLSLLVL 
HRLLCEHFRV LSTVHTHSSV KSVPENLLKC FGEQNKKQPR QDYQLGFTLI WKNVPKTQMK 
FSIQTMCPIE GEGNIARFLF SLFGQKHNAV NATLIDSWVD IAIFQLKEGS SKEKAAVFRS 
MNSALGKSPW LAGNELTVAD VVLWSVLQQI GGCSVTVPAN VQRWMRSCEN LAPFNTALKL 
LK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.