Details for: BRD3

Gene ID: 8019

Symbol: BRD3

Ensembl ID: ENSG00000169925

Description: bromodomain containing 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 184.5765
    Cell Significance Index: -28.7100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 109.0113
    Cell Significance Index: -27.6500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 71.1255
    Cell Significance Index: -29.3000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 64.3189
    Cell Significance Index: -26.1300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 59.8190
    Cell Significance Index: -30.7700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 48.4634
    Cell Significance Index: -32.5200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.7143
    Cell Significance Index: -26.4600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.2110
    Cell Significance Index: -33.5500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.0084
    Cell Significance Index: -29.4900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.6568
    Cell Significance Index: -34.1600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.0516
    Cell Significance Index: -24.7300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.2043
    Cell Significance Index: -11.3900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.3477
    Cell Significance Index: 81.5800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 2.2410
    Cell Significance Index: 221.6900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.8130
    Cell Significance Index: 19.7100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.7436
    Cell Significance Index: 1574.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.6858
    Cell Significance Index: 196.4700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.6420
    Cell Significance Index: 13.1100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3882
    Cell Significance Index: 18.9400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.3569
    Cell Significance Index: 70.6800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.3219
    Cell Significance Index: 143.7900
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.3000
    Cell Significance Index: 10.0200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.2741
    Cell Significance Index: 26.6700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.2236
    Cell Significance Index: 73.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7909
    Cell Significance Index: 108.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7475
    Cell Significance Index: 47.1100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6725
    Cell Significance Index: 46.5100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6229
    Cell Significance Index: 123.6200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.6180
    Cell Significance Index: 16.2500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.6108
    Cell Significance Index: 16.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5907
    Cell Significance Index: 118.4900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5832
    Cell Significance Index: 105.1300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5502
    Cell Significance Index: 35.5000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5324
    Cell Significance Index: 68.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4862
    Cell Significance Index: 265.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4848
    Cell Significance Index: 59.6100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4578
    Cell Significance Index: 25.6900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4120
    Cell Significance Index: 147.7900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4103
    Cell Significance Index: 181.4200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3892
    Cell Significance Index: 74.0600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3538
    Cell Significance Index: 7.6700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2990
    Cell Significance Index: 8.6200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2972
    Cell Significance Index: 18.2700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.2764
    Cell Significance Index: 3.5400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2190
    Cell Significance Index: 9.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2181
    Cell Significance Index: 11.4500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1856
    Cell Significance Index: 9.6400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1709
    Cell Significance Index: 4.5800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1544
    Cell Significance Index: 1.8400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1281
    Cell Significance Index: 3.5800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1152
    Cell Significance Index: 8.1500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0995
    Cell Significance Index: 4.6400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0973
    Cell Significance Index: 3.4200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0851
    Cell Significance Index: 6.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0815
    Cell Significance Index: 3.8300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0030
    Cell Significance Index: 0.3900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0026
    Cell Significance Index: 4.8700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0001
    Cell Significance Index: 0.1800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0008
    Cell Significance Index: -1.2100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0031
    Cell Significance Index: -2.2900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0042
    Cell Significance Index: -0.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0052
    Cell Significance Index: -0.1100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0098
    Cell Significance Index: -13.3100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0182
    Cell Significance Index: -11.5500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0249
    Cell Significance Index: -18.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0312
    Cell Significance Index: -23.1500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0327
    Cell Significance Index: -0.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0335
    Cell Significance Index: -15.2000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0481
    Cell Significance Index: -4.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0498
    Cell Significance Index: -28.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0502
    Cell Significance Index: -8.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0615
    Cell Significance Index: -38.4000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0727
    Cell Significance Index: -8.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0782
    Cell Significance Index: -11.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0895
    Cell Significance Index: -25.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0963
    Cell Significance Index: -3.0900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1026
    Cell Significance Index: -2.6200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1400
    Cell Significance Index: -16.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1757
    Cell Significance Index: -37.0100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1940
    Cell Significance Index: -14.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2119
    Cell Significance Index: -14.2500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2172
    Cell Significance Index: -5.2100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2372
    Cell Significance Index: -2.4600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2405
    Cell Significance Index: -5.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2461
    Cell Significance Index: -6.5700
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2685
    Cell Significance Index: -2.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3107
    Cell Significance Index: -32.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3151
    Cell Significance Index: -24.9600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.3457
    Cell Significance Index: -5.2500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3698
    Cell Significance Index: -10.6000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3960
    Cell Significance Index: -9.1500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4251
    Cell Significance Index: -26.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4341
    Cell Significance Index: -12.7900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4736
    Cell Significance Index: -5.3800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4781
    Cell Significance Index: -12.7900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4861
    Cell Significance Index: -21.5000
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.5080
    Cell Significance Index: -3.1800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5373
    Cell Significance Index: -13.4300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6088
    Cell Significance Index: -23.0600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6649
    Cell Significance Index: -21.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Bromodomain-containing protein**: BRD3 belongs to the bromodomain-containing protein family, characterized by the presence of a bromodomain, a protein-protein interaction domain that recognizes acetylated histones. 2. **High expression levels**: BRD3 is significantly expressed in various cell types, including neural crest cells, epithelial cells of the nephron, and skeletal muscle cells. 3. **Chromatin binding**: BRD3 binds to chromatin, where it regulates transcriptional activity and maintains chromatin organization. 4. **RNA polymerase II regulation**: BRD3 interacts with RNA polymerase II, a key enzyme involved in transcriptional regulation, to regulate gene expression. **Pathways and Functions:** 1. **Chromatin binding**: BRD3 binds to chromatin, where it regulates transcriptional activity and maintains chromatin organization. 2. **Lysine-acetylated histone binding**: BRD3 recognizes and binds to acetylated histones, which are modified by histone acetyltransferases (HATs). 3. **Chromatin organization**: BRD3 regulates chromatin organization by interacting with chromatin-associated proteins and maintaining the structure of chromatin. 4. **Molecular condensate scaffold activity**: BRD3 forms molecular condensates, which are dynamic structures that regulate gene expression and cellular differentiation. 5. **Regulation of transcription by RNA polymerase II**: BRD3 interacts with RNA polymerase II to regulate transcriptional activity and maintain gene expression. **Clinical Significance:** BRD3's involvement in chromatin regulation and cellular differentiation highlights its potential role in various diseases, including: 1. **Cancer**: BRD3 has been implicated in the regulation of gene expression in cancer cells, where it may contribute to tumorigenesis and cancer progression. 2. **Neurological disorders**: BRD3's involvement in chromatin regulation and neural cell differentiation suggests its potential role in neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Muscular dystrophy**: BRD3's expression in skeletal muscle cells highlights its potential role in muscular dystrophy, where it may contribute to muscle cell differentiation and function. In conclusion, BRD3 is a critical gene involved in chromatin regulation and cellular differentiation. Its high expression levels and involvement in various cellular processes make it a promising target for therapeutic interventions in various diseases. Further research is needed to fully elucidate the role of BRD3 in different diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 420672240

Symbol: BRD3_HUMAN

Name: Bromodomain-containing protein 3

UniProtKB Accession Codes:

Q15059 B1APD9 Q4G5Y3 Q5T1R7 Q8N5M3 Q92645

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 41 PDBsum 41 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 3 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7584044

Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7584044

DOI: 10.1093/dnares/1.5.223

PubMed ID: 16008511

Title: Differentially expressed genes in endothelial differentiation.

PubMed ID: 16008511

DOI: 10.1089/dna.2005.24.432

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9373153

Title: Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.

PubMed ID: 9373153

DOI: 10.1016/s0378-1119(97)00415-0

PubMed ID: 18406326

Title: The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription.

PubMed ID: 18406326

DOI: 10.1016/j.molcel.2008.01.018

PubMed ID: 17934517

Title: BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.

PubMed ID: 17934517

DOI: 10.1038/sj.onc.1210852

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20871596

Title: Selective inhibition of BET bromodomains.

PubMed ID: 20871596

DOI: 10.1038/nature09504

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 31969702

Title: Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.

PubMed ID: 31969702

DOI: 10.1038/s41586-020-1930-8

PubMed ID: 32895492

Title: lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation.

PubMed ID: 32895492

DOI: 10.1038/s41556-020-0572-2

PubMed ID: 32193360

Title: Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.

PubMed ID: 32193360

DOI: 10.1126/science.aaz8455

PubMed ID: 22464331

Title: Histone recognition and large-scale structural analysis of the human bromodomain family.

PubMed ID: 22464331

DOI: 10.1016/j.cell.2012.02.013

PubMed ID: 27105114

Title: Molecular coupling of histone crotonylation and active transcription by AF9 YEATS domain.

PubMed ID: 27105114

DOI: 10.1016/j.molcel.2016.03.028

PubMed ID: 29567837

Title: The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.

PubMed ID: 29567837

DOI: 10.1074/jbc.ra117.000678

PubMed ID: 33592170

Title: A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins.

PubMed ID: 33592170

DOI: 10.1016/j.str.2021.01.010

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 726
  • Mass: 79542
  • Checksum: 64F526FC3C1033AA
  • Sequence:
    • MSTATTVAPA GIPATPGPVN PPPPEVSNPS KPGRKTNQLQ YMQNVVVKTL WKHQFAWPFY 
QPVDAIKLNL PDYHKIIKNP MDMGTIKKRL ENNYYWSASE CMQDFNTMFT NCYIYNKPTD 
DIVLMAQALE KIFLQKVAQM PQEEVELLPP APKGKGRKPA AGAQSAGTQQ VAAVSSVSPA 
TPFQSVPPTV SQTPVIAATP VPTITANVTS VPVPPAAAPP PPATPIVPVV PPTPPVVKKK 
GVKRKADTTT PTTSAITASR SESPPPLSDP KQAKVVARRE SGGRPIKPPK KDLEDGEVPQ 
HAGKKGKLSE HLRYCDSILR EMLSKKHAAY AWPFYKPVDA EALELHDYHD IIKHPMDLST 
VKRKMDGREY PDAQGFAADV RLMFSNCYKY NPPDHEVVAM ARKLQDVFEM RFAKMPDEPV 
EAPALPAPAA PMVSKGAESS RSSEESSSDS GSSDSEEERA TRLAELQEQL KAVHEQLAAL 
SQAPVNKPKK KKEKKEKEKK KKDKEKEKEK HKVKAEEEKK AKVAPPAKQA QQKKAPAKKA 
NSTTTAGRQL KKGGKQASAS YDSEEEEEGL PMSYDEKRQL SLDINRLPGE KLGRVVHIIQ 
SREPSLRDSN PDEIEIDFET LKPTTLRELE RYVKSCLQKK QRKPFSASGK KQAAKSKEEL 
AQEKKKELEK RLQDVSGQLS SSKKPARKEK PGSAPSGGPS RLSSSSSSES GSSSSSGSSS 
DSSDSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.