Details for: HMGA2

Gene ID: 8091

Symbol: HMGA2

Ensembl ID: ENSG00000149948

Description: high mobility group AT-hook 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 70.2690
    Cell Significance Index: -10.9300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 42.1852
    Cell Significance Index: -10.7000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 39.4225
    Cell Significance Index: -16.2400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.7952
    Cell Significance Index: -13.3100
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 6.7955
    Cell Significance Index: 169.4600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 5.4549
    Cell Significance Index: 114.1800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.5753
    Cell Significance Index: 36.5300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 3.8606
    Cell Significance Index: 41.9700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.4541
    Cell Significance Index: -13.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 3.0897
    Cell Significance Index: 613.1600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.6810
    Cell Significance Index: 93.1700
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 2.6483
    Cell Significance Index: 30.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.1893
    Cell Significance Index: 122.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 2.1634
    Cell Significance Index: 63.7200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.6354
    Cell Significance Index: 43.8200
  • Cell Name: chondroblast (CL0000058)
    Fold Change: 1.6014
    Cell Significance Index: 9.4000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1476
    Cell Significance Index: 52.0200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0483
    Cell Significance Index: 199.5000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7549
    Cell Significance Index: 74.6800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5825
    Cell Significance Index: 318.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5019
    Cell Significance Index: 453.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4738
    Cell Significance Index: 13.2400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4072
    Cell Significance Index: 66.2200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4061
    Cell Significance Index: 44.1800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3771
    Cell Significance Index: 22.6400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.3589
    Cell Significance Index: 3.7200
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: 0.3412
    Cell Significance Index: 2.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3337
    Cell Significance Index: 9.6200
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.2691
    Cell Significance Index: 3.7800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1957
    Cell Significance Index: 4.2400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.1566
    Cell Significance Index: 2.0100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1269
    Cell Significance Index: 8.7800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1160
    Cell Significance Index: 2.9000
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.0961
    Cell Significance Index: 0.5700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0837
    Cell Significance Index: 5.4000
  • Cell Name: obsolete somatic cell (CL0002371)
    Fold Change: 0.0607
    Cell Significance Index: 0.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0464
    Cell Significance Index: 32.1200
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.0358
    Cell Significance Index: 0.2600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0160
    Cell Significance Index: 29.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0098
    Cell Significance Index: 15.0300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0012
    Cell Significance Index: 0.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.8900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0106
    Cell Significance Index: -0.2200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0108
    Cell Significance Index: -14.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0112
    Cell Significance Index: -1.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0143
    Cell Significance Index: -2.8800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0168
    Cell Significance Index: -0.5900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0196
    Cell Significance Index: -14.8600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0219
    Cell Significance Index: -16.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0223
    Cell Significance Index: -14.1600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0228
    Cell Significance Index: -1.4000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0232
    Cell Significance Index: -10.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0236
    Cell Significance Index: -17.4500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0241
    Cell Significance Index: -15.0300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0268
    Cell Significance Index: -0.5700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0275
    Cell Significance Index: -3.2000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0307
    Cell Significance Index: -17.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0315
    Cell Significance Index: -14.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0319
    Cell Significance Index: -11.4300
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0382
    Cell Significance Index: -0.2400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0472
    Cell Significance Index: -13.5900
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.0527
    Cell Significance Index: -0.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0628
    Cell Significance Index: -2.0100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0674
    Cell Significance Index: -12.1500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0687
    Cell Significance Index: -8.4500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0800
    Cell Significance Index: -16.8500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0827
    Cell Significance Index: -0.5600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0855
    Cell Significance Index: -12.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0884
    Cell Significance Index: -15.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0892
    Cell Significance Index: -2.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0951
    Cell Significance Index: -13.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0996
    Cell Significance Index: -11.4100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1196
    Cell Significance Index: -15.4600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1248
    Cell Significance Index: -12.9900
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: -0.1321
    Cell Significance Index: -0.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1349
    Cell Significance Index: -13.7800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1428
    Cell Significance Index: -2.1400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1440
    Cell Significance Index: -16.9900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1705
    Cell Significance Index: -2.5700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.1719
    Cell Significance Index: -2.6600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1907
    Cell Significance Index: -5.4700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1912
    Cell Significance Index: -14.6800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1996
    Cell Significance Index: -5.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2051
    Cell Significance Index: -16.2500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2177
    Cell Significance Index: -14.6400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2285
    Cell Significance Index: -17.0300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2394
    Cell Significance Index: -2.7200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2745
    Cell Significance Index: -16.8700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2877
    Cell Significance Index: -4.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2998
    Cell Significance Index: -15.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3009
    Cell Significance Index: -14.1400
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.3042
    Cell Significance Index: -4.2200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3072
    Cell Significance Index: -13.5900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3114
    Cell Significance Index: -4.4600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3183
    Cell Significance Index: -16.0900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3381
    Cell Significance Index: -4.0300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3445
    Cell Significance Index: -8.8600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3607
    Cell Significance Index: -13.6600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3637
    Cell Significance Index: -12.7400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3696
    Cell Significance Index: -11.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** HMGA2 is characterized by its ability to bind to specific DNA sequences, including CAMP response elements (CRE), and its involvement in various signaling pathways, including those related to cell proliferation, differentiation, and survival. The protein has a unique structure, consisting of three AT-hook domains, which are responsible for its high mobility on DNA. HMGA2 is also known for its ability to regulate the expression of other genes, including those involved in cell cycle progression, angiogenesis, and stem cell maintenance. **Pathways and Functions** HMGA2 is involved in a wide range of cellular processes, including: 1. **Cell Proliferation**: HMGA2 regulates the expression of genes involved in cell cycle progression, including those involved in DNA replication and repair. 2. **Angiogenesis**: HMGA2 promotes the expression of genes involved in angiogenesis, including vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF). 3. **Stem Cell Proliferation**: HMGA2 regulates the expression of genes involved in stem cell maintenance, including those involved in self-renewal and differentiation. 4. **Cell Differentiation**: HMGA2 regulates the expression of genes involved in cell differentiation, including those involved in chondrocyte and fat cell differentiation. 5. **DNA Repair**: HMGA2 regulates the expression of genes involved in DNA repair, including those involved in base excision repair and nucleotide excision repair. **Clinical Significance** HMGA2 has been implicated in various diseases, including: 1. **Cancer**: HMGA2 is overexpressed in many types of cancer, including breast, lung, and colon cancer, and is associated with poor prognosis. 2. **Cardiovascular Disease**: HMGA2 is involved in the regulation of vascular smooth muscle cell proliferation and is associated with cardiovascular disease. 3. **Neurological Disorders**: HMGA2 has been implicated in the regulation of neural stem cell proliferation and is associated with neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Bone Metastasis**: HMGA2 is involved in the regulation of bone metastasis and is associated with breast cancer. In conclusion, HMGA2 is a critical regulator of cellular processes, including cell proliferation, differentiation, and survival. Its dysregulation has been implicated in various diseases, including cancer, cardiovascular disease, and neurological disorders. Further research is needed to fully understand the role of HMGA2 in human disease and to develop effective therapeutic strategies for its inhibition.

Genular Protein ID: 1607863008

Symbol: HMGA2_HUMAN

Name: High mobility group protein HMGI-C

UniProtKB Accession Codes:

P52926 E7EP85 E7EWA2 Q1M182 Q1M185 Q1M186 Q1M187 Q1M188

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 18 Ensembl 6 ExpressionAtlas 1 GO 56 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 5 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 2 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 1 SignaLink 1 TopDownProteomics 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8198613

Title: Expression and cDNA cloning of human HMGI-C phosphoprotein.

PubMed ID: 8198613

DOI: 10.1006/bbrc.1994.1669

PubMed ID: 7670494

Title: Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours.

PubMed ID: 7670494

DOI: 10.1038/ng0895-436

PubMed ID: 7501444

Title: The gene for the human architectural transcription factor HMGI-C consists of five exons each coding for a distinct functional element.

PubMed ID: 7501444

DOI: 10.1093/nar/23.21.4262

PubMed ID: 8824803

Title: Genomic characterization of human HMGIC, a member of the accessory transcription factor family found at translocation breakpoints in lipomas.

PubMed ID: 8824803

DOI: 10.1006/geno.1996.0033

PubMed ID: 15882911

Title: Extensive expression studies revealed a complex alternative splicing pattern of the HMGA2 gene.

PubMed ID: 15882911

DOI: 10.1016/j.bbaexp.2005.03.006

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 9772904

Title: Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma.

PubMed ID: 9772904

DOI: 10.1016/s0165-4608(98)00038-7

PubMed ID: 9892177

Title: Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas.

PubMed ID: 9892177

PubMed ID: 11066083

Title: An identical HMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with t(3;12)(q27-28;q14-15).

PubMed ID: 11066083

DOI: 10.1002/1098-2264(2000)9999:9999<1::aid-gcc1043>3.3.co;2-e

PubMed ID: 12649198

Title: Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15.

PubMed ID: 12649198

PubMed ID: 14645522

Title: Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2.

PubMed ID: 14645522

DOI: 10.1128/mcb.23.24.9104-9116.2003

PubMed ID: 17767157

Title: A common variant of HMGA2 is associated with adult and childhood height in the general population.

PubMed ID: 17767157

DOI: 10.1038/ng2121

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 25809938

Title: A splicing mutation of the HMGA2 gene is associated with Silver-Russell syndrome phenotype.

PubMed ID: 25809938

DOI: 10.1038/jhg.2015.29

PubMed ID: 28796236

Title: Genetic disruption of the oncogenic HMGA2-PLAG1-IGF2 pathway causes fetal growth restriction.

PubMed ID: 28796236

DOI: 10.1038/gim.2017.105

Sequence Information:

  • Length: 109
  • Mass: 11832
  • Checksum: F36BABE623DA4615
  • Sequence:
    • MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP 
SKAAQKKAEA TGEKRPRGRP RKWPQQVVQK KPAQEETEET SSQESAEED

Genular Protein ID: 3868882451

Symbol: Q1M183_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q1M183

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 6 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1

Sequence Information:

  • Length: 147
  • Mass: 16325
  • Checksum: C846C41DF4490C25
  • Sequence:
    • MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP 
SKAAQKKAEA TGEKRPRGRP RKWAGVQWYN LGSLQPPPPR FKQFSCLRLL SSWDYRHPPP 
HPANFCIFSR DGVSPCWPGW SRTPDLR

Genular Protein ID: 1521738869

Symbol: F5H2A4_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5H2A4

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 5 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 118
  • Mass: 12714
  • Checksum: 05A17E34D52E0D8E
  • Sequence:
    • MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP 
SKAAQKKAEA TGEKRPRGRP RKWPQQVVQK KPAQVNVALP GKDHPGNLIY LLFSKNAT

Genular Protein ID: 2061850110

Symbol: F5H6H0_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5H6H0

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 5 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 3 MINT 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 STRING 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 147
  • Mass: 16424
  • Checksum: C9F6C41DF4490C35
  • Sequence:
    • MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP 
SKAAQKKAEA TGEKRPRGRP RKWAGVQWYN LGSLQPPPPR FKQFSCLRLL SSWDYRHPPP 
HPANFCIFSR DRVSPCWPGW SRTPDLR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.