Details for: CAPN2

Gene ID: 824

Symbol: CAPN2

Ensembl ID: ENSG00000162909

Description: calpain 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 354.0449
    Cell Significance Index: -55.0700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 217.4313
    Cell Significance Index: -55.1500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 126.6193
    Cell Significance Index: -51.4400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 125.7724
    Cell Significance Index: -59.3800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 112.3283
    Cell Significance Index: -57.7800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 88.8048
    Cell Significance Index: -59.5900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 54.4754
    Cell Significance Index: -52.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 44.9570
    Cell Significance Index: -55.4300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.3847
    Cell Significance Index: -49.2500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.5266
    Cell Significance Index: -36.1700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.3906
    Cell Significance Index: -44.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.2649
    Cell Significance Index: -56.2900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 2.7000
    Cell Significance Index: 62.3800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.5486
    Cell Significance Index: 69.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.7381
    Cell Significance Index: 81.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.5480
    Cell Significance Index: 72.7600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.3405
    Cell Significance Index: 39.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2860
    Cell Significance Index: 158.1200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.1781
    Cell Significance Index: 33.7700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.1656
    Cell Significance Index: 22.7500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.1429
    Cell Significance Index: 24.7600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.0794
    Cell Significance Index: 19.9500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9840
    Cell Significance Index: 135.1300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.9023
    Cell Significance Index: 116.5800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8567
    Cell Significance Index: 22.9600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8521
    Cell Significance Index: 153.6100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.7833
    Cell Significance Index: 40.8000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7101
    Cell Significance Index: 32.1900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7081
    Cell Significance Index: 386.7300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6190
    Cell Significance Index: 79.3500
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.6185
    Cell Significance Index: 8.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6021
    Cell Significance Index: 59.5600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5984
    Cell Significance Index: 214.6500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5945
    Cell Significance Index: 536.7700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.5799
    Cell Significance Index: 8.6900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5607
    Cell Significance Index: 41.7900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.5011
    Cell Significance Index: 8.8600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4975
    Cell Significance Index: 99.8000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4949
    Cell Significance Index: 80.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3932
    Cell Significance Index: 173.8500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3746
    Cell Significance Index: 10.4700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.3714
    Cell Significance Index: 18.7700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2449
    Cell Significance Index: 169.3900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2164
    Cell Significance Index: 36.9500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1307
    Cell Significance Index: 240.9700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1231
    Cell Significance Index: 90.2200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1194
    Cell Significance Index: 22.7300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0939
    Cell Significance Index: 3.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0640
    Cell Significance Index: 120.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0422
    Cell Significance Index: 31.9500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0400
    Cell Significance Index: 61.5600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0272
    Cell Significance Index: 0.5700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0039
    Cell Significance Index: 1.7900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0023
    Cell Significance Index: 0.1200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0148
    Cell Significance Index: -2.9400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0170
    Cell Significance Index: -12.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0281
    Cell Significance Index: -17.8400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0282
    Cell Significance Index: -38.3700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0562
    Cell Significance Index: -0.9400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0575
    Cell Significance Index: -35.9300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0649
    Cell Significance Index: -2.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0655
    Cell Significance Index: -4.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0675
    Cell Significance Index: -38.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0731
    Cell Significance Index: -7.4700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1346
    Cell Significance Index: -19.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1527
    Cell Significance Index: -32.1600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1609
    Cell Significance Index: -46.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1657
    Cell Significance Index: -18.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1902
    Cell Significance Index: -22.1600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2074
    Cell Significance Index: -22.5600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2107
    Cell Significance Index: -5.6300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2170
    Cell Significance Index: -16.6600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2797
    Cell Significance Index: -22.1500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3452
    Cell Significance Index: -4.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3539
    Cell Significance Index: -21.7500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4440
    Cell Significance Index: -50.6800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4733
    Cell Significance Index: -55.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4739
    Cell Significance Index: -49.3500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5099
    Cell Significance Index: -17.7200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5682
    Cell Significance Index: -14.9400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.5779
    Cell Significance Index: -37.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5836
    Cell Significance Index: -32.7500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.6778
    Cell Significance Index: -7.7000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7125
    Cell Significance Index: -37.4100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7126
    Cell Significance Index: -31.5200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.7266
    Cell Significance Index: -4.3900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7350
    Cell Significance Index: -49.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7900
    Cell Significance Index: -49.7900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8563
    Cell Significance Index: -52.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.9041
    Cell Significance Index: -26.0500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.9243
    Cell Significance Index: -23.7600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9245
    Cell Significance Index: -35.0100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.9448
    Cell Significance Index: -20.2000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.1041
    Cell Significance Index: -40.5300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.1687
    Cell Significance Index: -24.8900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -1.1823
    Cell Significance Index: -16.8300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.1962
    Cell Significance Index: -20.5000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.2909
    Cell Significance Index: -22.3200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.3485
    Cell Significance Index: -47.2400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.3668
    Cell Significance Index: -36.5600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** Calpain 2 is a calcium-dependent protease that is activated by the binding of calcium ions to its regulatory subunit. This activation leads to the cleavage of various cellular substrates, including proteins involved in cytoskeleton organization, cell signaling, and protein degradation. Calpain 2 is a homodimeric enzyme, consisting of two identical subunits, and is highly specific for cysteine-containing peptides. Its activity is regulated by various mechanisms, including calcium ion binding, protein binding, and proteolysis. **Pathways and Functions** Calpain 2 is involved in several cellular pathways, including: 1. **Apoptosis regulation**: Calpain 2 is involved in the regulation of apoptosis, a process of programmed cell death. It cleaves and activates pro-apoptotic proteins, leading to the activation of caspases and the execution of cell death. 2. **Cytoskeleton organization**: Calpain 2 is involved in the regulation of cytoskeleton organization, including the degradation of actin filaments and microtubules. This leads to changes in cell shape, motility, and adhesion. 3. **Protein degradation**: Calpain 2 is involved in the degradation of various cellular proteins, including those involved in cell signaling, protein synthesis, and protein degradation. 4. **Inflammation regulation**: Calpain 2 is involved in the regulation of inflammation, including the cleavage of pro-inflammatory cytokines and the activation of anti-inflammatory pathways. 5. **Neurodegenerative diseases**: Calpain 2 has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. **Clinical Significance** Calpain 2 has been implicated in several diseases, including: 1. **Neurodegenerative disorders**: Calpain 2 has been implicated in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. 2. **Cancer**: Calpain 2 has been implicated in the progression of various cancers, including breast cancer, colon cancer, and lung cancer. 3. **Inflammatory conditions**: Calpain 2 has been implicated in the regulation of inflammation, including the cleavage of pro-inflammatory cytokines and the activation of anti-inflammatory pathways. 4. **Cardiovascular disease**: Calpain 2 has been implicated in the regulation of cardiovascular function, including the degradation of cardiac myosin and the activation of anti-inflammatory pathways. In conclusion, calpain 2 is a calcium-dependent protease that plays a crucial role in various cellular processes, including apoptosis, cytoskeleton organization, and protein degradation. Its dysregulation has been implicated in several diseases, including neurodegenerative disorders, cancer, inflammatory conditions, and cardiovascular disease. Further studies are needed to fully understand the mechanisms of calpain 2 and its role in human disease.

Genular Protein ID: 1372319129

Symbol: CAN2_HUMAN

Name: Calpain-2 catalytic subunit

UniProtKB Accession Codes:

P17655 A6NDG7 B7ZA96 E7ES58 Q16738 Q6PJT3 Q8WU26 Q9HBB1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CPTAC 2 CTD 1 ChEBI 26 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 10 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 42 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2852952

Title: Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease.

PubMed ID: 2852952

DOI: 10.1021/bi00421a022

PubMed ID: 10944468

Title: cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.

PubMed ID: 10944468

DOI: 10.1006/bbrc.2000.3282

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2539381

Title: Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease.

PubMed ID: 2539381

DOI: 10.1016/s0021-9258(18)83364-6

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 17650508

Title: Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease.

PubMed ID: 17650508

DOI: 10.1074/jbc.m609608200

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10639123

Title: The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.

PubMed ID: 10639123

DOI: 10.1073/pnas.97.2.588

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 700
  • Mass: 79995
  • Checksum: 8CF8294351A024E3
  • Sequence:
    • MAGIAAKLAK DREAAEGLGS HDRAIKYLNQ DYEALRNECL EAGTLFQDPS FPAIPSALGF 
KELGPYSSKT RGIEWKRPTE ICADPQFIIG GATRTDICQG ALGDCWLLAA IASLTLNEEI 
LARVVPLNQS FQENYAGIFH FQFWQYGEWV EVVVDDRLPT KDGELLFVHS AEGSEFWSAL 
LEKAYAKING CYEALSGGAT TEGFEDFTGG IAEWYELKKP PPNLFKIIQK ALQKGSLLGC 
SIDITSAADS EAITFQKLVK GHAYSVTGAE EVESNGSLQK LIRIRNPWGE VEWTGRWNDN 
CPSWNTIDPE ERERLTRRHE DGEFWMSFSD FLRHYSRLEI CNLTPDTLTS DTYKKWKLTK 
MDGNWRRGST AGGCRNYPNT FWMNPQYLIK LEEEDEDEED GESGCTFLVG LIQKHRRRQR 
KMGEDMHTIG FGIYEVPEEL SGQTNIHLSK NFFLTNRARE RSDTFINLRE VLNRFKLPPG 
EYILVPSTFE PNKDGDFCIR VFSEKKADYQ AVDDEIEANL EEFDISEDDI DDGFRRLFAQ 
LAGEDAEISA FELQTILRRV LAKRQDIKSD GFSIETCKIM VDMLDSDGSG KLGLKEFYIL 
WTKIQKYQKI YREIDVDRSG TMNSYEMRKA LEEAGFKMPC QLHQVIVARF ADDQLIIDFD 
NFVRCLVRLE TLFKIFKQLD PENTGTIELD LISWLCFSVL

Genular Protein ID: 4290277911

Symbol: B4DN77_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DN77

Database IDs:

ARBA 18 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 3 InterPro 13 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 Pfam 3 PharmGKB 1 RefSeq 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 622
  • Mass: 71582
  • Checksum: 4BCE8EA579A9120C
  • Sequence:
    • MEICADPQFI IGGATRTDIC QGALGDCWLL AAIASLTLNE EILARVVPLN QSFQENYAGI 
FHFQFWQYGE WVEVVVDDRL PTKDGELLFV HSAEGSEFWS ALLEKAYAKI NGCYEALSGG 
ATTEGFEDFT GGIAEWYELK KPPPNLFKII QKALQKGSLL GCSIDITSAA DSEAITFQKL 
VKGHAYSVTG AEEVESNGSL QKLIRIRNPW GEVEWTGRWN DNCPSWNTID PEERERLTRR 
HEDGEFWMSF SDFLRHYSRL EICNLTPDTL TSDTYKKWKL TKMDGNWRRG STAGGCRNYP 
NTFWMNPQYL IKLEEEDEDE EDGESGCTFL VGLIQKHRRR QRKMCEDMHT IGFGIYEVPE 
ELSGQTNIHL SKNFFLTNRA RERSDTFINL REVLNRFKLP PGEYILVPFT FEPNKDGDFC 
IRVFSEKKAD YQAVDDEIEA NLEEFDISED DIDDGFRRLF AQLAGEDAEI SAFELQTILR 
RVLAKRQDIK SDGFSIETCK IMVDMLDSDG SGKLGLKEFY ILWTKIQKYQ KIYREIDVDR 
SGTMNSYEMR KALEEAGFKM PCQLHQVIVA RFADDQLIID FDNFVRCLVR LETLFKIFKQ 
LDPENTGTIE LDLISWLCFS VL

Genular Protein ID: 1482384951

Symbol: Q59EF6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EF6

Database IDs:

ARBA 18 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 3 IntAct 1 InterPro 13 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 729
  • Mass: 83109
  • Checksum: 39E151FF908DB2F7
  • Sequence:
    • APGPGRAPAE RSAESPRPFS AQYGRRDRSM AGIAAKLAKD REAAEGLGSH ERAIKYLNQD 
YEALRNECLE AGTLFQDPSF PAIPSALGFK ELGPYSSKTR GIEWKRPTEI CADPQFIIGG 
ATRTDICQGA LGDCWLLAAI ASLTLNEEIL ARVVPLNQCF QENYAGIFHF QFWQYGEWVE 
VVVDDRLPTK DGELLFVHSA EGSEFWSALL EKAYAKINGC YEALSGGATT EGFEDFTGGI 
AEWYESKKPP PNLFKIIQKA LQKGSLLGCS IDITSAADSE AITFQKLVKG HAYSVTGAEE 
VESNGSLQKL IRIRNPWGEV EWTGRWNDNC PSWNTIDPEE RERLTRRHED GEFWMSFSDF 
LRHYSRLEIC NLTPDTLTSD TYKKWKLTKM DGNWRRGSTA GGCRNYPNTF WMNPQYLIKL 
EEEDEDEEDG ESGCTFLVGL IQKHRRRQRK MGEDMHTIGF GIYEVPEELS GQTNIHLSKN 
FFLTNRARER SDTFINLREV LNRFKLPPGE YILVPSTFEP NKDGDFCIRV FSEKKADYQA 
VDDEIEANLE EFDISEDDID DGFRRLFAQL AGEDAEISAF ELQTILRRVL AKRQDIKSDG 
FSIETCKIMV DMLDSDGSGK LGLKEFYILW TKIQKYQKIY REIDVDRSGT MNSYEMRKAL 
EEAGFKMPCQ LHQVIVARFA DDQLIIDFDN FVRCLVRLET LFKIFKQLDP ENTGTIELDL 
ISWLCFSVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.