Details for: CAPN2

Gene ID: 824

Symbol: CAPN2

Ensembl ID: ENSG00000162909

Description: calpain 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 3.13
    Marker Score: 3,773
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 2.77
    Marker Score: 9,512
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.7
    Marker Score: 1,807
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 2.54
    Marker Score: 1,732
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 2.52
    Marker Score: 21,876
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.46
    Marker Score: 3,567
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.42
    Marker Score: 6,482
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.39
    Marker Score: 2,097
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.35
    Marker Score: 1,854
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.33
    Marker Score: 49,743
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 2.31
    Marker Score: 11,345
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.29
    Marker Score: 3,805
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.27
    Marker Score: 2,411
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 2.22
    Marker Score: 11,689
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 2.19
    Marker Score: 4,006
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2.18
    Marker Score: 6,859
  • Cell Name: club cell (CL0000158)
    Fold Change: 2.13
    Marker Score: 2,489
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.13
    Marker Score: 119,073
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.13
    Marker Score: 34,180
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 2.09
    Marker Score: 3,084
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.09
    Marker Score: 6,589
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 2.06
    Marker Score: 654
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 2.04
    Marker Score: 955
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.04
    Marker Score: 2,183
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.04
    Marker Score: 69,517
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 2.04
    Marker Score: 3,878
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.03
    Marker Score: 15,091
  • Cell Name: basal cell (CL0000646)
    Fold Change: 2.02
    Marker Score: 2,607
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2
    Marker Score: 739
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.97
    Marker Score: 937
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.97
    Marker Score: 12,853
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 1.96
    Marker Score: 695
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.95
    Marker Score: 564
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.95
    Marker Score: 16,781
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.92
    Marker Score: 4,683
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.91
    Marker Score: 3,382
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 1.89
    Marker Score: 8,120
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.86
    Marker Score: 918
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 1.86
    Marker Score: 1,139
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.85
    Marker Score: 2,486
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.83
    Marker Score: 528
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.82
    Marker Score: 7,830
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.8
    Marker Score: 809
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.8
    Marker Score: 14,035
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.79
    Marker Score: 1,826
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.79
    Marker Score: 1,815
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.77
    Marker Score: 1,532
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.76
    Marker Score: 11,274
  • Cell Name: peptic cell (CL0000155)
    Fold Change: 1.76
    Marker Score: 735
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.75
    Marker Score: 4,404
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.75
    Marker Score: 1,272
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.7
    Marker Score: 3,879
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.7
    Marker Score: 16,792
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 1.69
    Marker Score: 1,509
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.68
    Marker Score: 2,670
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.67
    Marker Score: 10,675
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.66
    Marker Score: 1,752
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.64
    Marker Score: 1,768
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.64
    Marker Score: 706
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 1.63
    Marker Score: 953
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.62
    Marker Score: 2,607
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.62
    Marker Score: 399
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.61
    Marker Score: 1,736
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 1.61
    Marker Score: 3,919
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.59
    Marker Score: 3,963
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.59
    Marker Score: 1,003
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.59
    Marker Score: 1,326
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.58
    Marker Score: 18,339
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.58
    Marker Score: 2,232
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.55
    Marker Score: 1,820
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.54
    Marker Score: 3,001
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 1.54
    Marker Score: 391
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 1.53
    Marker Score: 818
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 1.53
    Marker Score: 337
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.53
    Marker Score: 4,280
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 1.52
    Marker Score: 430
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.51
    Marker Score: 3,430
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.51
    Marker Score: 485
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.51
    Marker Score: 79,712
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.5
    Marker Score: 7,208
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.49
    Marker Score: 1,335
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 1.49
    Marker Score: 1,089
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.48
    Marker Score: 846
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.48
    Marker Score: 779
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.47
    Marker Score: 3,855
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 1.47
    Marker Score: 3,726
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 1.46
    Marker Score: 587
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 1.46
    Marker Score: 898
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.46
    Marker Score: 2,008
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 1.45
    Marker Score: 4,228
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.44
    Marker Score: 332
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.44
    Marker Score: 716
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.44
    Marker Score: 2,116
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.44
    Marker Score: 791
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.43
    Marker Score: 2,427
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 1.43
    Marker Score: 340
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.42
    Marker Score: 1,475
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.42
    Marker Score: 1,566
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 1.4
    Marker Score: 511
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 1.4
    Marker Score: 304

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** Calpain 2 is a calcium-dependent protease that is activated by the binding of calcium ions to its regulatory subunit. This activation leads to the cleavage of various cellular substrates, including proteins involved in cytoskeleton organization, cell signaling, and protein degradation. Calpain 2 is a homodimeric enzyme, consisting of two identical subunits, and is highly specific for cysteine-containing peptides. Its activity is regulated by various mechanisms, including calcium ion binding, protein binding, and proteolysis. **Pathways and Functions** Calpain 2 is involved in several cellular pathways, including: 1. **Apoptosis regulation**: Calpain 2 is involved in the regulation of apoptosis, a process of programmed cell death. It cleaves and activates pro-apoptotic proteins, leading to the activation of caspases and the execution of cell death. 2. **Cytoskeleton organization**: Calpain 2 is involved in the regulation of cytoskeleton organization, including the degradation of actin filaments and microtubules. This leads to changes in cell shape, motility, and adhesion. 3. **Protein degradation**: Calpain 2 is involved in the degradation of various cellular proteins, including those involved in cell signaling, protein synthesis, and protein degradation. 4. **Inflammation regulation**: Calpain 2 is involved in the regulation of inflammation, including the cleavage of pro-inflammatory cytokines and the activation of anti-inflammatory pathways. 5. **Neurodegenerative diseases**: Calpain 2 has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. **Clinical Significance** Calpain 2 has been implicated in several diseases, including: 1. **Neurodegenerative disorders**: Calpain 2 has been implicated in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. 2. **Cancer**: Calpain 2 has been implicated in the progression of various cancers, including breast cancer, colon cancer, and lung cancer. 3. **Inflammatory conditions**: Calpain 2 has been implicated in the regulation of inflammation, including the cleavage of pro-inflammatory cytokines and the activation of anti-inflammatory pathways. 4. **Cardiovascular disease**: Calpain 2 has been implicated in the regulation of cardiovascular function, including the degradation of cardiac myosin and the activation of anti-inflammatory pathways. In conclusion, calpain 2 is a calcium-dependent protease that plays a crucial role in various cellular processes, including apoptosis, cytoskeleton organization, and protein degradation. Its dysregulation has been implicated in several diseases, including neurodegenerative disorders, cancer, inflammatory conditions, and cardiovascular disease. Further studies are needed to fully understand the mechanisms of calpain 2 and its role in human disease.

Genular Protein ID: 1372319129

Symbol: CAN2_HUMAN

Name: Calpain-2 catalytic subunit

UniProtKB Accession Codes:

P17655 A6NDG7 B7ZA96 E7ES58 Q16738 Q6PJT3 Q8WU26 Q9HBB1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CPTAC 2 CTD 1 ChEBI 26 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 10 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 42 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2852952

Title: Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease.

PubMed ID: 2852952

DOI: 10.1021/bi00421a022

PubMed ID: 10944468

Title: cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.

PubMed ID: 10944468

DOI: 10.1006/bbrc.2000.3282

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2539381

Title: Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease.

PubMed ID: 2539381

DOI: 10.1016/s0021-9258(18)83364-6

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 17650508

Title: Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease.

PubMed ID: 17650508

DOI: 10.1074/jbc.m609608200

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10639123

Title: The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.

PubMed ID: 10639123

DOI: 10.1073/pnas.97.2.588

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 700
  • Mass: 79995
  • Checksum: 8CF8294351A024E3
  • Sequence:
    • MAGIAAKLAK DREAAEGLGS HDRAIKYLNQ DYEALRNECL EAGTLFQDPS FPAIPSALGF 
KELGPYSSKT RGIEWKRPTE ICADPQFIIG GATRTDICQG ALGDCWLLAA IASLTLNEEI 
LARVVPLNQS FQENYAGIFH FQFWQYGEWV EVVVDDRLPT KDGELLFVHS AEGSEFWSAL 
LEKAYAKING CYEALSGGAT TEGFEDFTGG IAEWYELKKP PPNLFKIIQK ALQKGSLLGC 
SIDITSAADS EAITFQKLVK GHAYSVTGAE EVESNGSLQK LIRIRNPWGE VEWTGRWNDN 
CPSWNTIDPE ERERLTRRHE DGEFWMSFSD FLRHYSRLEI CNLTPDTLTS DTYKKWKLTK 
MDGNWRRGST AGGCRNYPNT FWMNPQYLIK LEEEDEDEED GESGCTFLVG LIQKHRRRQR 
KMGEDMHTIG FGIYEVPEEL SGQTNIHLSK NFFLTNRARE RSDTFINLRE VLNRFKLPPG 
EYILVPSTFE PNKDGDFCIR VFSEKKADYQ AVDDEIEANL EEFDISEDDI DDGFRRLFAQ 
LAGEDAEISA FELQTILRRV LAKRQDIKSD GFSIETCKIM VDMLDSDGSG KLGLKEFYIL 
WTKIQKYQKI YREIDVDRSG TMNSYEMRKA LEEAGFKMPC QLHQVIVARF ADDQLIIDFD 
NFVRCLVRLE TLFKIFKQLD PENTGTIELD LISWLCFSVL

Genular Protein ID: 1482384951

Symbol: Q59EF6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EF6

Database IDs:

ARBA 16 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 DNASU 1 EC 1 EMBL 2 GO 5 Gene3D 3 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 12 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 729
  • Mass: 83109
  • Checksum: 39E151FF908DB2F7
  • Sequence:
    • APGPGRAPAE RSAESPRPFS AQYGRRDRSM AGIAAKLAKD REAAEGLGSH ERAIKYLNQD 
YEALRNECLE AGTLFQDPSF PAIPSALGFK ELGPYSSKTR GIEWKRPTEI CADPQFIIGG 
ATRTDICQGA LGDCWLLAAI ASLTLNEEIL ARVVPLNQCF QENYAGIFHF QFWQYGEWVE 
VVVDDRLPTK DGELLFVHSA EGSEFWSALL EKAYAKINGC YEALSGGATT EGFEDFTGGI 
AEWYESKKPP PNLFKIIQKA LQKGSLLGCS IDITSAADSE AITFQKLVKG HAYSVTGAEE 
VESNGSLQKL IRIRNPWGEV EWTGRWNDNC PSWNTIDPEE RERLTRRHED GEFWMSFSDF 
LRHYSRLEIC NLTPDTLTSD TYKKWKLTKM DGNWRRGSTA GGCRNYPNTF WMNPQYLIKL 
EEEDEDEEDG ESGCTFLVGL IQKHRRRQRK MGEDMHTIGF GIYEVPEELS GQTNIHLSKN 
FFLTNRARER SDTFINLREV LNRFKLPPGE YILVPSTFEP NKDGDFCIRV FSEKKADYQA 
VDDEIEANLE EFDISEDDID DGFRRLFAQL AGEDAEISAF ELQTILRRVL AKRQDIKSDG 
FSIETCKIMV DMLDSDGSGK LGLKEFYILW TKIQKYQKIY REIDVDRSGT MNSYEMRKAL 
EEAGFKMPCQ LHQVIVARFA DDQLIIDFDN FVRCLVRLET LFKIFKQLDP ENTGTIELDL 
ISWLCFSVL

Genular Protein ID: 4290277911

Symbol: B4DN77_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DN77

Database IDs:

ARBA 16 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 DNASU 1 EC 1 EMBL 2 GO 5 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 12 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 Pfam 3 PharmGKB 1 RefSeq 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 622
  • Mass: 71582
  • Checksum: 4BCE8EA579A9120C
  • Sequence:
    • MEICADPQFI IGGATRTDIC QGALGDCWLL AAIASLTLNE EILARVVPLN QSFQENYAGI 
FHFQFWQYGE WVEVVVDDRL PTKDGELLFV HSAEGSEFWS ALLEKAYAKI NGCYEALSGG 
ATTEGFEDFT GGIAEWYELK KPPPNLFKII QKALQKGSLL GCSIDITSAA DSEAITFQKL 
VKGHAYSVTG AEEVESNGSL QKLIRIRNPW GEVEWTGRWN DNCPSWNTID PEERERLTRR 
HEDGEFWMSF SDFLRHYSRL EICNLTPDTL TSDTYKKWKL TKMDGNWRRG STAGGCRNYP 
NTFWMNPQYL IKLEEEDEDE EDGESGCTFL VGLIQKHRRR QRKMCEDMHT IGFGIYEVPE 
ELSGQTNIHL SKNFFLTNRA RERSDTFINL REVLNRFKLP PGEYILVPFT FEPNKDGDFC 
IRVFSEKKAD YQAVDDEIEA NLEEFDISED DIDDGFRRLF AQLAGEDAEI SAFELQTILR 
RVLAKRQDIK SDGFSIETCK IMVDMLDSDG SGKLGLKEFY ILWTKIQKYQ KIYREIDVDR 
SGTMNSYEMR KALEEAGFKM PCQLHQVIVA RFADDQLIID FDNFVRCLVR LETLFKIFKQ 
LDPENTGTIE LDLISWLCFS VL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.