Details for: SMARCA5

Gene ID: 8467

Symbol: SMARCA5

Ensembl ID: ENSG00000153147

Description: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 4.1
    Marker Score: 17090
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 3.08
    Marker Score: 12838
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.98
    Marker Score: 2111
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.92
    Marker Score: 2313
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.85
    Marker Score: 7179
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.85
    Marker Score: 10968
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.81
    Marker Score: 15873
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.8
    Marker Score: 2582
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 1.79
    Marker Score: 1404
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.77
    Marker Score: 2614
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.76
    Marker Score: 61136.5
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.76
    Marker Score: 1773
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.76
    Marker Score: 4776
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.72
    Marker Score: 5898
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.7
    Marker Score: 734
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.69
    Marker Score: 1792
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.68
    Marker Score: 1124
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.67
    Marker Score: 399
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.67
    Marker Score: 1611
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.66
    Marker Score: 4646
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.65
    Marker Score: 909
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.65
    Marker Score: 3444
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.64
    Marker Score: 16507
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.64
    Marker Score: 16602
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.63
    Marker Score: 1190
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.63
    Marker Score: 10639
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.63
    Marker Score: 18379
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.63
    Marker Score: 55400
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.61
    Marker Score: 464
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.61
    Marker Score: 4373
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.61
    Marker Score: 498
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.61
    Marker Score: 2207.5
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.61
    Marker Score: 2013
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.6
    Marker Score: 2726
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.6
    Marker Score: 1705
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 1.58
    Marker Score: 1901
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.58
    Marker Score: 1704
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.58
    Marker Score: 13718.5
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.58
    Marker Score: 1662
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.58
    Marker Score: 587
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.56
    Marker Score: 1647
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.55
    Marker Score: 463
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.55
    Marker Score: 776
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.55
    Marker Score: 6500
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.54
    Marker Score: 807
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.53
    Marker Score: 1437
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.52
    Marker Score: 5620
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.52
    Marker Score: 529
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.52
    Marker Score: 614
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.5
    Marker Score: 605
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.5
    Marker Score: 17409
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.5
    Marker Score: 2120
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.5
    Marker Score: 1932
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.5
    Marker Score: 1019
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 1.49
    Marker Score: 564
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.49
    Marker Score: 3752
  • Cell Name: neural cell (CL0002319)
    Fold Change: 1.49
    Marker Score: 717
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.48
    Marker Score: 1796.5
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.48
    Marker Score: 1972
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.48
    Marker Score: 2355
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.48
    Marker Score: 1786
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.48
    Marker Score: 602.5
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.46
    Marker Score: 2553
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 1.46
    Marker Score: 1109
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 1.46
    Marker Score: 1589
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 1.46
    Marker Score: 319
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.45
    Marker Score: 9458
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.45
    Marker Score: 2564
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.44
    Marker Score: 3398
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 1.44
    Marker Score: 1449
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.43
    Marker Score: 14809
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.43
    Marker Score: 1928
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.43
    Marker Score: 54397
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.43
    Marker Score: 976.5
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 1.43
    Marker Score: 400.5
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 1.42
    Marker Score: 1681
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.42
    Marker Score: 326
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.42
    Marker Score: 945
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.41
    Marker Score: 413
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.41
    Marker Score: 2174
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 1.4
    Marker Score: 370
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.4
    Marker Score: 1450
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 1.39
    Marker Score: 1042
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 1.39
    Marker Score: 678
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.38
    Marker Score: 11895
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.38
    Marker Score: 480
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.38
    Marker Score: 399
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.38
    Marker Score: 340
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 1.38
    Marker Score: 864
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 1.37
    Marker Score: 731
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.37
    Marker Score: 912
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.37
    Marker Score: 5386
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.37
    Marker Score: 84195
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.37
    Marker Score: 3662
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.36
    Marker Score: 848
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.36
    Marker Score: 274
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.36
    Marker Score: 17888
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.35
    Marker Score: 2971
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.35
    Marker Score: 21713
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.35
    Marker Score: 1371

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key Characteristics:** 1. **Chromatin remodeling**: SMARCA5 is a component of the SWI/SNF complex, which is responsible for dynamic chromatin remodeling, a process that regulates gene expression and cellular differentiation. 2. **Actin-dependent**: SMARCA5 is unique among SWI/SNF family members due to its association with actin filaments, which are essential for maintaining chromatin structure and facilitating complex movement. 3. **Tissue-specific expression**: SMARCA5 is expressed in various cell types, including epithelial cells, neural progenitor cells, and myeloid leukocytes, highlighting its diverse roles in different tissues. 4. **Disease association**: SMARCA5 has been implicated in several human diseases, including cancer, neurodegenerative disorders, and immunological conditions. **Pathways and Functions:** 1. **Chromatin organization**: SMARCA5 plays a crucial role in maintaining chromatin structure and organization, influencing gene expression and cellular differentiation. 2. **DNA damage response**: SMARCA5 is involved in the recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double-strand breaks. 3. **Transcriptional control**: SMARCA5 regulates transcription by RNA polymerase II, influencing the expression of genes involved in cell cycle progression and DNA repair. 4. **Epigenetic regulation**: SMARCA5 is involved in epigenetic regulation of gene expression, modulating the activity of histone-modifying enzymes and chromatin-remodeling complexes. 5. **Cell cycle regulation**: SMARCA5 is essential for maintaining proper cell cycle progression, influencing the expression of genes involved in cell cycle checkpoints and DNA repair. **Clinical Significance:** 1. **Cancer association**: SMARCA5 mutations have been identified in various cancers, including breast, ovarian, and prostate cancer, highlighting its role in tumorigenesis. 2. **Neurodegenerative disorders**: SMARCA5 has been implicated in neurodegenerative disorders, such as frontotemporal dementia and amyotrophic lateral sclerosis, suggesting a role in neuronal function and survival. 3. **Immunological conditions**: SMARCA5 is expressed in immune cells and has been implicated in immunological conditions, such as type I NK T cell dysfunction. 4. **Diagnosis and treatment**: SMARCA5 mutations can be used as biomarkers for diagnosis and as targets for therapeutic interventions in cancer and neurodegenerative disorders. In conclusion, SMARCA5 is a multifunctional gene that plays a crucial role in regulating chromatin structure and gene expression. Its involvement in various cellular processes and its association with human diseases highlight the need for further research into the molecular mechanisms underlying its functions and its potential as a therapeutic target.

Genular Protein ID: 3646918632

Symbol: SMCA5_HUMAN

Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

UniProtKB Accession Codes:

O60264

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CPTAC 1 CTD 1 ChEBI 1 ChiTaRS 1 ComplexPortal 6 DIP 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 2 EMDB 1 EPD 1 Ensembl 1 GO 45 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 1 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9730600

Title: Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI.

PubMed ID: 9730600

DOI: 10.1159/000015027

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10880450

Title: HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins.

PubMed ID: 10880450

DOI: 10.1093/emboj/19.13.3377

PubMed ID: 10914549

Title: Chromatin remodeling gene SMARCA5 is dysregulated in primitive hematopoietic cells of acute leukemia.

PubMed ID: 10914549

DOI: 10.1038/sj.leu.2401807

PubMed ID: 10655480

Title: A family of chromatin remodeling factors related to Williams syndrome transcription factor.

PubMed ID: 10655480

DOI: 10.1073/pnas.97.3.1038

PubMed ID: 11435432

Title: Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H.

PubMed ID: 11435432

DOI: 10.1074/jbc.m104163200

PubMed ID: 11980720

Title: WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.

PubMed ID: 11980720

DOI: 10.1093/emboj/21.9.2231

PubMed ID: 12434153

Title: An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin.

PubMed ID: 12434153

DOI: 10.1038/ng1046

PubMed ID: 12198550

Title: A chromatin remodelling complex that loads cohesin onto human chromosomes.

PubMed ID: 12198550

DOI: 10.1038/nature01024

PubMed ID: 12972596

Title: Functional analysis of the subunits of the chromatin assembly factor RSF.

PubMed ID: 12972596

DOI: 10.1128/mcb.23.19.6759-6768.2003

PubMed ID: 15284901

Title: Functional diversity of ISWI complexes.

PubMed ID: 15284901

DOI: 10.1139/o04-044

PubMed ID: 14759371

Title: The histone-fold protein complex CHRAC-15/17 enhances nucleosome sliding and assembly mediated by ACF.

PubMed ID: 14759371

DOI: 10.1016/s1097-2765(03)00523-9

PubMed ID: 15543136

Title: The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci.

PubMed ID: 15543136

DOI: 10.1038/ncb1196

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16603771

Title: The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.

PubMed ID: 16603771

DOI: 10.1074/jbc.m600233200

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23911928

Title: SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.

PubMed ID: 23911928

DOI: 10.1016/j.molcel.2013.06.018

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26100909

Title: BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase.

PubMed ID: 26100909

DOI: 10.1073/pnas.1424705112

PubMed ID: 28801535

Title: Expansion of the ISWI chromatin remodeler family with new active complexes.

PubMed ID: 28801535

DOI: 10.15252/embr.201744011

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30926617

Title: BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV.

PubMed ID: 30926617

DOI: 10.26508/lsa.201800108

PubMed ID: 33092197

Title: A Comprehensive Proteomics Analysis of the JC Virus (JCV) Large and Small Tumor Antigen Interacting Proteins: Large T Primarily Targets the Host Protein Complexes with V-ATPase and Ubiquitin Ligase Activities While Small t Mostly Associates with Those Having Phosphatase and Chromatin-Remodeling Functions.

PubMed ID: 33092197

DOI: 10.3390/v12101192

Sequence Information:

  • Length: 1052
  • Mass: 121905
  • Checksum: 6CC8CB25BAF7A876
  • Sequence:
    • MSSAAEPPPP PPPESAPSKP AASIASGGSN SSNKGGPEGV AAQAVASAAS AGPADAEMEE 
IFDDASPGKQ KEIQEPDPTY EEKMQTDRAN RFEYLLKQTE LFAHFIQPAA QKTPTSPLKM 
KPGRPRIKKD EKQNLLSVGD YRHRRTEQEE DEELLTESSK ATNVCTRFED SPSYVKWGKL 
RDYQVRGLNW LISLYENGIN GILADEMGLG KTLQTISLLG YMKHYRNIPG PHMVLVPKST 
LHNWMSEFKR WVPTLRSVCL IGDKEQRAAF VRDVLLPGEW DVCVTSYEML IKEKSVFKKF 
NWRYLVIDEA HRIKNEKSKL SEIVREFKTT NRLLLTGTPL QNNLHELWSL LNFLLPDVFN 
SADDFDSWFD TNNCLGDQKL VERLHMVLRP FLLRRIKADV EKSLPPKKEV KIYVGLSKMQ 
REWYTRILMK DIDILNSAGK MDKMRLLNIL MQLRKCCNHP YLFDGAEPGP PYTTDMHLVT 
NSGKMVVLDK LLPKLKEQGS RVLIFSQMTR VLDILEDYCM WRNYEYCRLD GQTPHDERQD 
SINAYNEPNS TKFVFMLSTR AGGLGINLAT ADVVILYDSD WNPQVDLQAM DRAHRIGQTK 
TVRVFRFITD NTVEERIVER AEMKLRLDSI VIQQGRLVDQ NLNKIGKDEM LQMIRHGATH 
VFASKESEIT DEDIDGILER GAKKTAEMNE KLSKMGESSL RNFTMDTESS VYNFEGEDYR 
EKQKIAFTEW IEPPKRERKA NYAVDAYFRE ALRVSEPKAP KAPRPPKQPN VQDFQFFPPR 
LFELLEKEIL FYRKTIGYKV PRNPELPNAA QAQKEEQLKI DEAESLNDEE LEEKEKLLTQ 
GFTNWNKRDF NQFIKANEKW GRDDIENIAR EVEGKTPEEV IEYSAVFWER CNELQDIEKI 
MAQIERGEAR IQRRISIKKA LDTKIGRYKA PFHQLRISYG TNKGKNYTEE EDRFLICMLH 
KLGFDKENVY DELRQCIRNS PQFRFDWFLK SRTAMELQRR CNTLITLIER ENMELEEKEK 
AEKKKRGPKP STQKRKMDGA PDGRGRKKKL KL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.