Details for: COPS3

Gene ID: 8533

Symbol: COPS3

Ensembl ID: ENSG00000141030

Description: COP9 signalosome subunit 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 118.3257
    Cell Significance Index: -18.4100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 109.0902
    Cell Significance Index: -27.6700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 91.6379
    Cell Significance Index: -37.7500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 85.8993
    Cell Significance Index: -40.5600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 82.5339
    Cell Significance Index: -33.5300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 75.2597
    Cell Significance Index: -38.7100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 60.4265
    Cell Significance Index: -40.5500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 35.4965
    Cell Significance Index: -33.8900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.6061
    Cell Significance Index: -35.2700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.3854
    Cell Significance Index: -30.5000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.8630
    Cell Significance Index: -38.9200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.6771
    Cell Significance Index: -23.5800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.8159
    Cell Significance Index: -10.5400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.6619
    Cell Significance Index: 99.7700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1036
    Cell Significance Index: 179.4900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0116
    Cell Significance Index: 65.2700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.0085
    Cell Significance Index: 35.0500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.9668
    Cell Significance Index: 10.5100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.9197
    Cell Significance Index: 19.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.8410
    Cell Significance Index: 99.1800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6673
    Cell Significance Index: 46.1500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6135
    Cell Significance Index: 38.6700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5895
    Cell Significance Index: 80.9500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5750
    Cell Significance Index: 26.8100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5724
    Cell Significance Index: 7.8100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5700
    Cell Significance Index: 114.3500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5688
    Cell Significance Index: 40.2300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5671
    Cell Significance Index: 250.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5564
    Cell Significance Index: 303.8800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4960
    Cell Significance Index: 23.3100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4681
    Cell Significance Index: 12.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4396
    Cell Significance Index: 54.0600
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.4251
    Cell Significance Index: 3.2100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.4154
    Cell Significance Index: 12.2000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4123
    Cell Significance Index: 285.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4037
    Cell Significance Index: 72.7800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4013
    Cell Significance Index: 51.8500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3740
    Cell Significance Index: 63.8600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3500
    Cell Significance Index: 69.4500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3242
    Cell Significance Index: 16.8400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2613
    Cell Significance Index: 7.4900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2396
    Cell Significance Index: 85.9600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2268
    Cell Significance Index: 29.0700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2124
    Cell Significance Index: 5.7800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2001
    Cell Significance Index: 180.6500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1882
    Cell Significance Index: 9.8800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1688
    Cell Significance Index: 12.5800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1457
    Cell Significance Index: 3.8300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1388
    Cell Significance Index: 26.4100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1219
    Cell Significance Index: 2.6400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0881
    Cell Significance Index: 1.0500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0663
    Cell Significance Index: 1.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0574
    Cell Significance Index: 2.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0462
    Cell Significance Index: 1.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0271
    Cell Significance Index: 2.0800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0106
    Cell Significance Index: 1.0500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0031
    Cell Significance Index: -0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0047
    Cell Significance Index: -8.8200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0098
    Cell Significance Index: -7.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0120
    Cell Significance Index: -8.8600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0132
    Cell Significance Index: -24.3900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0144
    Cell Significance Index: -22.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0192
    Cell Significance Index: -26.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0214
    Cell Significance Index: -15.7200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0234
    Cell Significance Index: -14.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0293
    Cell Significance Index: -18.6400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0364
    Cell Significance Index: -0.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0368
    Cell Significance Index: -3.7600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0392
    Cell Significance Index: -22.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0440
    Cell Significance Index: -2.4700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0503
    Cell Significance Index: -22.8200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0562
    Cell Significance Index: -1.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0850
    Cell Significance Index: -17.9000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0885
    Cell Significance Index: -12.8600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1082
    Cell Significance Index: -31.1400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1170
    Cell Significance Index: -13.6300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1428
    Cell Significance Index: -3.6700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1531
    Cell Significance Index: -3.9100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1770
    Cell Significance Index: -6.2200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1822
    Cell Significance Index: -20.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2107
    Cell Significance Index: -12.9500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2263
    Cell Significance Index: -6.0500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2598
    Cell Significance Index: -29.6600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2720
    Cell Significance Index: -18.2900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2813
    Cell Significance Index: -4.8200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3217
    Cell Significance Index: -3.3300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3642
    Cell Significance Index: -6.4400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3651
    Cell Significance Index: -38.0200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3972
    Cell Significance Index: -31.4600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4834
    Cell Significance Index: -21.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5081
    Cell Significance Index: -31.1500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5172
    Cell Significance Index: -12.6200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5555
    Cell Significance Index: -4.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5997
    Cell Significance Index: -22.7100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6063
    Cell Significance Index: -16.2500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.6628
    Cell Significance Index: -12.2500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.6793
    Cell Significance Index: -14.5200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.7181
    Cell Significance Index: -16.5900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7238
    Cell Significance Index: -21.3200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.7720
    Cell Significance Index: -8.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **COPS3 gene structure:** The COPS3 gene encodes a subunit of the COP9 signalosome complex, which is a hetero-oligomeric protein complex. 2. **Significant expression:** COPS3 is highly expressed in erythroid progenitor cells, oogonial cells, and other cell types involved in hematopoiesis and germ cell development. 3. **Multiple cellular functions:** COPS3 participates in various cellular processes, including DNA damage response, protein neddylation, transcription regulation, and membrane trafficking. 4. **Interactions with other proteins:** COPS3 interacts with other proteins, such as CSN1, CSN2, and CSN6, to form the CSN complex. **Pathways and Functions:** 1. **DNA damage response:** COPS3 plays a crucial role in the regulation of DNA damage response, particularly in the formation of the 8-oxo-guanine (8-oxoG) endonuclease (GGN) complex. 2. **Protein neddylation:** COPS3 is involved in the neddylation of proteins, which is a post-translational modification that regulates protein activity and stability. 3. **Transcription regulation:** COPS3 interacts with transcription factors, such as p53 and p21, to regulate gene expression in response to DNA damage. 4. **Clathrin-mediated endocytosis:** COPS3 is involved in the regulation of clathrin-mediated endocytosis, a process essential for maintaining cellular homeostasis. 5. **Membrane trafficking:** COPS3 participates in the regulation of membrane trafficking, including vesicle-mediated transport and endocytosis. **Clinical Significance:** The dysregulation of COPS3 has been implicated in various diseases, including: 1. **Cancer:** Altered expression of COPS3 has been observed in various types of cancer, including breast, lung, and colon cancer. 2. **Neurological disorders:** COPS3 has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Immunological disorders:** COPS3 has been implicated in immunological disorders, including autoimmune diseases and immunodeficiency syndromes. In conclusion, the COPS3 gene plays a critical role in maintaining cellular homeostasis through its involvement in DNA damage response, protein neddylation, transcription regulation, and membrane trafficking. Further research is necessary to fully elucidate the functions of COPS3 and its role in human disease.

Genular Protein ID: 2066446534

Symbol: CSN3_HUMAN

Name: COP9 signalosome complex subunit 3

UniProtKB Accession Codes:

Q9UNS2 B2R683 B4DY81 O43191 Q7LDR6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EMDB 13 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 4 RefSeq 8 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9535219

Title: A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits.

PubMed ID: 9535219

DOI: 10.1096/fasebj.12.6.469

PubMed ID: 10191102

Title: Subunit 3 of the COP9 signal transduction complex is conserved from plants to humans and maps within the Smith-Magenis syndrome critical region in 17p11.2.

PubMed ID: 10191102

DOI: 10.1006/geno.1998.5748

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 11285227

Title: COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system.

PubMed ID: 11285227

DOI: 10.1093/emboj/20.7.1630

PubMed ID: 11418127

Title: CSN3 interacts with IKKgamma and inhibits TNF- but not IL-1-induced NF-kappaB activation.

PubMed ID: 11418127

DOI: 10.1016/s0014-5793(01)02535-2

PubMed ID: 11337588

Title: Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome.

PubMed ID: 11337588

DOI: 10.1126/science.1059780

PubMed ID: 12220626

Title: Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome.

PubMed ID: 12220626

DOI: 10.1016/s0014-5793(02)03147-2

PubMed ID: 12732143

Title: The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

PubMed ID: 12732143

DOI: 10.1016/s0092-8674(03)00316-7

PubMed ID: 12628923

Title: Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.

PubMed ID: 12628923

DOI: 10.1093/emboj/cdg127

PubMed ID: 12917637

Title: Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation.

PubMed ID: 12917637

DOI: 10.1038/sj.onc.1206671

PubMed ID: 15325100

Title: Amplification and overexpression of genes in 17p11.2 approximately p12 in osteosarcoma.

PubMed ID: 15325100

DOI: 10.1016/j.cancergencyto.2004.03.007

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18850735

Title: Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.

PubMed ID: 18850735

DOI: 10.1021/pr800574c

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26456823

Title: CSNAP is a stoichiometric subunit of the COP9 signalosome.

PubMed ID: 26456823

DOI: 10.1016/j.celrep.2015.09.021

PubMed ID: 26030138

Title: Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

PubMed ID: 26030138

DOI: 10.1371/journal.pone.0128558

Sequence Information:

  • Length: 423
  • Mass: 47873
  • Checksum: 1D371050C7D7BF8D
  • Sequence:
    • MASALEQFVN SVRQLSAQGQ MTQLCELINK SGELLAKNLS HLDTVLGALD VQEHSLGVLA 
VLFVKFSMPS VPDFETLFSQ VQLFISTCNG EHIRYATDTF AGLCHQLTNA LVERKQPLRG 
IGILKQAIDK MQMNTNQLTS IHADLCQLCL LAKCFKPALP YLDVDMMDIC KENGAYDAKH 
FLCYYYYGGM IYTGLKNFER ALYFYEQAIT TPAMAVSHIM LESYKKYILV SLILLGKVQQ 
LPKYTSQIVG RFIKPLSNAY HELAQVYSTN NPSELRNLVN KHSETFTRDN NMGLVKQCLS 
SLYKKNIQRL TKTFLTLSLQ DMASRVQLSG PQEAEKYVLH MIEDGEIFAS INQKDGMVSF 
HDNPEKYNNP AMLHNIDQEM LKCIELDERL KAMDQEITVN PQFVQKSMGS QEDDSGNKPS 
SYS

Genular Protein ID: 2214498548

Symbol: B4DN01_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DN01

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 293
  • Mass: 33573
  • Checksum: 8F06AFA6F6A66A23
  • Sequence:
    • MQMNTNQLTS IHADLCQLCL LAKCFKPALP YLDVDMMDIC KENGAYDAKH FLCYYYYGGM 
IYTGLKNFER ALYFYEQAIT TPAMAVSHIV LESYKKYILV SLILLGKVQQ LPKYTSQIVG 
RFIKPLSNAY HELAQVYSTN NPSELRNLVN KHSETFTRDN NMGLVKQCLS SLYKKNIQRL 
TKTFLTLSLQ DMASRVQLSG PQEAEKYVLH MIEDGEIFAS INQKDGMVSF HDNPEKYNNP 
AMLHNIDQEM LKCIELDERL KAMDQEITVN PQFVQKSMGS QEDDSGNKPS SYS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.