Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 250.2809
Cell Significance Index: -38.9300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 153.9169
Cell Significance Index: -39.0400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 86.8418
Cell Significance Index: -41.0000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 81.6724
Cell Significance Index: -33.1800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 34.8680
Cell Significance Index: -33.2900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 31.6232
Cell Significance Index: -38.9900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 12.1220
Cell Significance Index: -26.5300 - Cell Name: colon endothelial cell (CL1001572)
Fold Change: 11.3074
Cell Significance Index: 8.6300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.8276
Cell Significance Index: -38.7800 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 3.8703
Cell Significance Index: 31.5600 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 3.4046
Cell Significance Index: 17.9200 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.5279
Cell Significance Index: 18.9000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.2007
Cell Significance Index: 26.2900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.9317
Cell Significance Index: 62.6500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.9085
Cell Significance Index: 11.6400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8512
Cell Significance Index: 168.9300 - Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: 0.7451
Cell Significance Index: 12.8000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.6525
Cell Significance Index: 17.4900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.5148
Cell Significance Index: 13.7500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.4489
Cell Significance Index: 52.3200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4072
Cell Significance Index: 77.5000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3392
Cell Significance Index: 43.4900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2919
Cell Significance Index: 17.9400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2779
Cell Significance Index: 122.8700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2503
Cell Significance Index: 50.2100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2467
Cell Significance Index: 134.7400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2448
Cell Significance Index: 87.8200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1413
Cell Significance Index: 64.1300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1245
Cell Significance Index: 112.4000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.1176
Cell Significance Index: 1.8200 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1092
Cell Significance Index: 0.6600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0712
Cell Significance Index: 134.0500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0407
Cell Significance Index: 28.1500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0344
Cell Significance Index: 6.2100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0313
Cell Significance Index: 4.3100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0066
Cell Significance Index: -4.9700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0156
Cell Significance Index: -2.5400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0220
Cell Significance Index: -0.4600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0224
Cell Significance Index: -16.5700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0249
Cell Significance Index: -45.9200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0257
Cell Significance Index: -14.5100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0284
Cell Significance Index: -17.7500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0290
Cell Significance Index: -44.6900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0345
Cell Significance Index: -46.9100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0418
Cell Significance Index: -1.4700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0503
Cell Significance Index: -31.9500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0507
Cell Significance Index: -37.1500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0545
Cell Significance Index: -5.3900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0564
Cell Significance Index: -2.9400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0782
Cell Significance Index: -9.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0877
Cell Significance Index: -9.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0961
Cell Significance Index: -2.7700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1077
Cell Significance Index: -31.0000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1249
Cell Significance Index: -3.5800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.1249
Cell Significance Index: -13.5900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1322
Cell Significance Index: -27.8500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1641
Cell Significance Index: -16.7600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1657
Cell Significance Index: -28.3000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1684
Cell Significance Index: -4.2100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1760
Cell Significance Index: -10.7900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2217
Cell Significance Index: -10.0500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2488
Cell Significance Index: -36.1700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2812
Cell Significance Index: -19.8900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3016
Cell Significance Index: -10.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3040
Cell Significance Index: -39.2700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3069
Cell Significance Index: -35.0300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3075
Cell Significance Index: -18.4600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3085
Cell Significance Index: -9.8800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3117
Cell Significance Index: -8.7100 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.3132
Cell Significance Index: -5.5400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3158
Cell Significance Index: -5.2900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3197
Cell Significance Index: -22.1100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3197
Cell Significance Index: -36.6300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3235
Cell Significance Index: -38.1500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.3833
Cell Significance Index: -8.3100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3948
Cell Significance Index: -20.7300 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.4229
Cell Significance Index: -6.7100 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.4234
Cell Significance Index: -6.0900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4449
Cell Significance Index: -9.2300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4727
Cell Significance Index: -37.4400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4771
Cell Significance Index: -36.6200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5284
Cell Significance Index: -39.3800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5377
Cell Significance Index: -34.6900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.5856
Cell Significance Index: -16.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.5900
Cell Significance Index: -27.7300 - Cell Name: embryonic fibroblast (CL2000042)
Fold Change: -0.6250
Cell Significance Index: -2.9900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.6446
Cell Significance Index: -36.1700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.6645
Cell Significance Index: -34.5200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.6677
Cell Significance Index: -42.0800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.7794
Cell Significance Index: -39.3900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.7837
Cell Significance Index: -11.8100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.7957
Cell Significance Index: -37.1000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.7968
Cell Significance Index: -19.1100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.8354
Cell Significance Index: -36.9500 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.8439
Cell Significance Index: -11.8000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8696
Cell Significance Index: -23.2600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.9009
Cell Significance Index: -33.0700 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: -0.9506
Cell Significance Index: -7.5100 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -1.0044
Cell Significance Index: -11.4100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -1.0304
Cell Significance Index: -39.0200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1860132011
Symbol: NRP2_HUMAN
Name: Neuropilin-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9331348
Title: Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III.
PubMed ID: 9331348
PubMed ID: 9529250
Title: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor.
PubMed ID: 9529250
PubMed ID: 11112349
Title: Genomic organization of human neuropilin-1 and neuropilin-2 genes: identification and distribution of splice variants and soluble isoforms.
PubMed ID: 11112349
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10748121
Title: Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165.
PubMed ID: 10748121
PubMed ID: 10520995
Title: Plexins are a large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates.
PubMed ID: 10520995
PubMed ID: 30057110
Title: An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor.
PubMed ID: 30057110
PubMed ID: 17989695
Title: Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.
PubMed ID: 17989695
PubMed ID: 22365152
Title: de novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP.
PubMed ID: 22365152
Sequence Information:
- Length: 931
- Mass: 104831
- Checksum: 270CBAE69A0A797C
- Sequence:
MDMFPLTWVF LALYFSRHQV RGQPDPPCGG RLNSKDAGYI TSPGYPQDYP SHQNCEWIVY APEPNQKIVL NFNPHFEIEK HDCKYDFIEI RDGDSESADL LGKHCGNIAP PTIISSGSML YIKFTSDYAR QGAGFSLRYE IFKTGSEDCS KNFTSPNGTI ESPGFPEKYP HNLDCTFTIL AKPKMEIILQ FLIFDLEHDP LQVGEGDCKY DWLDIWDGIP HVGPLIGKYC GTKTPSELRS STGILSLTFH TDMAVAKDGF SARYYLVHQE PLENFQCNVP LGMESGRIAN EQISASSTYS DGRWTPQQSR LHGDDNGWTP NLDSNKEYLQ VDLRFLTMLT AIATQGAISR ETQNGYYVKS YKLEVSTNGE DWMVYRHGKN HKVFQANNDA TEVVLNKLHA PLLTRFVRIR PQTWHSGIAL RLELFGCRVT DAPCSNMLGM LSGLIADSQI SASSTQEYLW SPSAARLVSS RSGWFPRIPQ AQPGEEWLQV DLGTPKTVKG VIIQGARGGD SITAVEARAF VRKFKVSYSL NGKDWEYIQD PRTQQPKLFE GNMHYDTPDI RRFDPIPAQY VRVYPERWSP AGIGMRLEVL GCDWTDSKPT VETLGPTVKS EETTTPYPTE EEATECGENC SFEDDKDLQL PSGFNCNFDF LEEPCGWMYD HAKWLRTTWA SSSSPNDRTF PDDRNFLRLQ SDSQREGQYA RLISPPVHLP RSPVCMEFQY QATGGRGVAL QVVREASQES KLLWVIREDQ GGEWKHGRII LPSYDMEYQI VFEGVIGKGR SGEIAIDDIR ISTDVPLENC MEPISAFAGE NFKVDIPEIH EREGYEDEID DEYEVDWSNS SSATSGSGAP STDKEKSWLY TLDPILITII AMSSLGVLLG ATCAGLLLYC TCSYSGLSSR SCTTLENYNF ELYDGLKHKV KMNHQKCCSE A
Genular Protein ID: 2364919600
Symbol: Q7Z3T9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 931
- Mass: 104750
- Checksum: CD7D2DF3D2756D9F
- Sequence:
MDMFPLTWVF LALYFSRHQV RGQPDPPCGG RLNSKDAGYI TSPGSPQDYP SHQNCEWIVY APEPNQKIVL NFNPHFEIEK HDCKYDFIEI RDGDSESADL LGKHCGNIAP PTIISSGSML YIKFTSDYAR QGAGFSLRYE IFKTGSEDCS KNFTSPNGTI ESPGFPEKYP HNLDCTFTIL AKPKMEIILQ FLIFDLEHDP LQVGEGDCKY DWLDIWDGIP HVGPLIGKYC GTKTPSELRS STGILSLTFH TDMAVAKDGF SARYYLVHQE PLENFQCNVP LGMESGRIAN EQISASSTYS DGRWTPQQSR LHGDDNGWTP NLDSNKEYLQ VDLRFLTMLT AIATQGAISR ETQNGYYVKS YKLEVSTNGE DWMVYRHGKN HKVFQANNDA TEVVLNKLHA PLLTRFVRIR PQTWHSGIAL RLELFGCRVT DAPCSNMLGM LSGLIADSQI SASSTQEYLW SPSAARLVSS RSGWFPRIPQ AQPGEEWLQV DLGTPKTVKG VIIQGARGGD SITAVEARAF VRKFKVSYSL NGKDWEYIQD PRTQQPKLFE GNMHYDTPDI RRFDPIPAQY VRVYPERWSP AGIGMRLEVL GCDWTDSKPT VETLGPTVKS EETTTPYPTE EEATECGENC SFEDDKDLQL PSGFNCNFDF LEEPCGWMYD HAKWLRTTWA SSSSPNDRTF PDDRNFLRLQ SDSQREGQYA RLISPPVHLP RSPVRMEFQY QATGGRGVAL QVVREASQES KLLWVIREDQ GGEWKHGRII LPSYDMEYQI VFEGVIGKGR SGEIAIDGIR ISTDVPLENC MEPISAFAGE NFKVDIPEIH EREGYEDEID DEYEVDWSNS SSATSGSGAP STDKEKSWLY TLDPILITII AMSSLGVLLG ATCAGLLLYC TCSYSGLSSR SCTTLENYNF ELYDGLKHKV KMNHQKCCSE A
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.