Details for: CFD
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 207.5924
Cell Significance Index: -32.2900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 127.0879
Cell Significance Index: -32.2400 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 82.7290
Cell Significance Index: -34.0800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 70.2511
Cell Significance Index: -28.5400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 67.9061
Cell Significance Index: -32.0600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 62.4338
Cell Significance Index: -32.1200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 30.2490
Cell Significance Index: -28.8800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 26.0999
Cell Significance Index: -32.1800 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 24.4158
Cell Significance Index: 165.4300 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 21.9838
Cell Significance Index: 65.3800 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 18.8745
Cell Significance Index: 49.7900 - Cell Name: preadipocyte (CL0002334)
Fold Change: 12.0269
Cell Significance Index: 234.7300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 11.9939
Cell Significance Index: -32.1300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 8.3017
Cell Significance Index: 237.9800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.9295
Cell Significance Index: -31.2900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 7.6439
Cell Significance Index: 141.2800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.6185
Cell Significance Index: -23.4000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 6.6618
Cell Significance Index: -14.5800 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 5.9409
Cell Significance Index: 36.7600 - Cell Name: fibroblast of the aortic adventitia (CL0002547)
Fold Change: 5.8534
Cell Significance Index: 59.0700 - Cell Name: theca cell (CL0000503)
Fold Change: 2.6111
Cell Significance Index: 15.3400 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 2.2238
Cell Significance Index: 5.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.8925
Cell Significance Index: 360.1600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.7883
Cell Significance Index: 245.5800 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 1.6260
Cell Significance Index: 23.3500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.5462
Cell Significance Index: 152.9500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.4871
Cell Significance Index: 31.6700 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.4228
Cell Significance Index: 15.5300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.2613
Cell Significance Index: 65.5200 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 1.1293
Cell Significance Index: 14.2200 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.0126
Cell Significance Index: 11.1900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.0023
Cell Significance Index: 70.8900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8933
Cell Significance Index: 806.5700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.8349
Cell Significance Index: 107.0300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.7266
Cell Significance Index: 54.1500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.6645
Cell Significance Index: 33.5800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6103
Cell Significance Index: 99.2600 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.4188
Cell Significance Index: 6.4800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2909
Cell Significance Index: 128.6100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2648
Cell Significance Index: 18.3200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1645
Cell Significance Index: 12.6300 - Cell Name: embryonic fibroblast (CL2000042)
Fold Change: 0.1547
Cell Significance Index: 0.7400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1542
Cell Significance Index: 18.9700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1523
Cell Significance Index: 17.7500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1187
Cell Significance Index: 64.8200 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1020
Cell Significance Index: 13.1800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0761
Cell Significance Index: 13.7300 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0710
Cell Significance Index: 7.2500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0489
Cell Significance Index: 0.8700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0284
Cell Significance Index: 53.4700 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.0273
Cell Significance Index: 0.1300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0268
Cell Significance Index: 1.2600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0159
Cell Significance Index: -0.5600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0183
Cell Significance Index: -33.6800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0202
Cell Significance Index: -15.2600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0240
Cell Significance Index: -36.9200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0281
Cell Significance Index: -38.2100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0387
Cell Significance Index: -28.4000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0442
Cell Significance Index: -28.0400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0472
Cell Significance Index: -1.1800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0497
Cell Significance Index: -36.8500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0606
Cell Significance Index: -21.7300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0639
Cell Significance Index: -36.0200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0685
Cell Significance Index: -31.1000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0722
Cell Significance Index: -45.0800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1006
Cell Significance Index: -28.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1191
Cell Significance Index: -23.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1418
Cell Significance Index: -28.4400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1849
Cell Significance Index: -38.9500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1982
Cell Significance Index: -12.1500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2001
Cell Significance Index: -29.0800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.2162
Cell Significance Index: -6.2300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2356
Cell Significance Index: -10.6800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2454
Cell Significance Index: -12.7800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2476
Cell Significance Index: -29.2000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2520
Cell Significance Index: -43.0300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2696
Cell Significance Index: -28.0700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2752
Cell Significance Index: -31.5300 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.3624
Cell Significance Index: -2.2300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3634
Cell Significance Index: -11.6400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3679
Cell Significance Index: -5.0200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3726
Cell Significance Index: -24.0400 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.3747
Cell Significance Index: -4.8100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3765
Cell Significance Index: -29.8200 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.4318
Cell Significance Index: -6.4700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.4403
Cell Significance Index: -9.5400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4451
Cell Significance Index: -11.4400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.4480
Cell Significance Index: -12.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.4783
Cell Significance Index: -22.3000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4865
Cell Significance Index: -4.4800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4964
Cell Significance Index: -26.0700 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.5276
Cell Significance Index: -8.3700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.5592
Cell Significance Index: -35.2500 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.5653
Cell Significance Index: -5.4500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.6307
Cell Significance Index: -16.8400 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.6455
Cell Significance Index: -12.6200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.6510
Cell Significance Index: -36.5300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.6889
Cell Significance Index: -14.7300 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.6933
Cell Significance Index: -30.1500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.6979
Cell Significance Index: -25.6200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2003327440
Symbol: CFAD_HUMAN
Name: Complement factor D
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1374388
Title: Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue.
PubMed ID: 1374388
PubMed ID: 6383466
Title: Amino acid sequence of human D of the alternative complement pathway.
PubMed ID: 6383466
DOI: 10.1021/bi00306a025
PubMed ID: 6363133
Title: Amino acid sequence of human factor D of the complement system. Similarity in sequence between factor D and proteases of non-plasma origin.
PubMed ID: 6363133
PubMed ID: 6987665
Title: Partial amino acid sequence of human factor D: homology with serine proteases.
PubMed ID: 6987665
PubMed ID: 6776531
Title: Active site amino acid sequence of human factor D.
PubMed ID: 6776531
PubMed ID: 6821372
Title: Factor D of the alternative pathway of human complement. Purification, alignment and N-terminal amino acid sequences of the major cyanogen bromide fragments, and localization of the serine residue at the active site.
PubMed ID: 6821372
DOI: 10.1042/bj1870863
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 8289289
Title: Structure of human factor D. A complement system protein at 2.0-A resolution.
PubMed ID: 8289289
PubMed ID: 7592653
Title: Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.
PubMed ID: 7592653
PubMed ID: 16527897
Title: Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections.
PubMed ID: 16527897
Sequence Information:
- Length: 253
- Mass: 27033
- Checksum: 78B06C209DEEA362
- Sequence:
MHSWERLAVL VLLGAAACAA PPRGRILGGR EAEAHARPYM ASVQLNGAHL CGGVLVAEQW VLSAAHCLED AADGKVQVLL GAHSLSQPEP SKRLYDVLRA VPHPDSQPDT IDHDLLLLQL SEKATLGPAV RPLPWQRVDR DVAPGTLCDV AGWGIVNHAG RRPDSLQHVL LPVLDRATCN RRTHHDGAIT ERLMCAESNR RDSCKGDSGG PLVCGGVLEG VVTSGSRVCG NRKKPGIYTR VASYAAWIDS VLA
Genular Protein ID: 728180445
Symbol: K7ERG9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
Sequence Information:
- Length: 260
- Mass: 27863
- Checksum: 271B5A14D64E0990
- Sequence:
MHSWERLAVL VLLGAAACGE EAWAWAAPPR GRILGGREAE AHARPYMASV QLNGAHLCGG VLVAEQWVLS AAHCLEDAAD GKVQVLLGAH SLSQPEPSKR LYDVLRAVPH PDSQPDTIDH DLLLLQLSEK ATLGPAVRPL PWQRVDRDVA PGTLCDVAGW GIVNHAGRRP DSLQHVLLPV LDRATCNRRT HHDGAITERL MCAESNRRDS CKGDSGGPLV CGGVLEGVVT SGSRVCGNRK KPGIYTRVAS YAAWIDSVLA
Genular Protein ID: 1971628381
Symbol: A6XNE2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 260
- Mass: 27780
- Checksum: EC76ECCBFAFCC2B7
- Sequence:
MHSWERLAVL VLLGAAACGE EAWACAAPPR GRILGGREAE AHARPYMASV QLNGAHLCGG VLVAEQWVLS AAHCLEDAAD GKVQVLLGAH SLSQPEPSKR LYDVLRAVPH PDSQPDTIDH DLLLLQLSEK ATLGPAVRPL PWQRVDRDVA PGTLCDVAGW GIVNHAGRRP DSLQHVLLPV LDRATCNRRT HHDGAITERL MCAESNRRDS CKGDSGGPLV CGGVLEGVVT SGSRVCGNRK KPGIYTRVAS YAAWIDSVLA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.