Details for: DOK1

Gene ID: 1796

Symbol: DOK1

Ensembl ID: ENSG00000115325

Description: docking protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 57.6038
    Cell Significance Index: -8.9600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 22.9062
    Cell Significance Index: -5.8100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 21.7842
    Cell Significance Index: -8.8500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 21.4139
    Cell Significance Index: -10.1100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 19.5573
    Cell Significance Index: -10.0600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 9.3428
    Cell Significance Index: -8.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.5996
    Cell Significance Index: -9.3700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.4328
    Cell Significance Index: -9.6000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 1.8142
    Cell Significance Index: -4.8600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.3479
    Cell Significance Index: -2.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8507
    Cell Significance Index: 768.0900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6603
    Cell Significance Index: 71.8200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6178
    Cell Significance Index: 37.0900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.6091
    Cell Significance Index: 17.8900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5847
    Cell Significance Index: 95.0900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.4104
    Cell Significance Index: 7.5900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3469
    Cell Significance Index: 23.9900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3072
    Cell Significance Index: 19.8200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3014
    Cell Significance Index: 35.5400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2707
    Cell Significance Index: 7.2400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2607
    Cell Significance Index: 6.9900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1900
    Cell Significance Index: 8.6100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1833
    Cell Significance Index: 18.1300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1822
    Cell Significance Index: 34.6800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1803
    Cell Significance Index: 9.3900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1742
    Cell Significance Index: 5.0200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1665
    Cell Significance Index: 90.9200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1336
    Cell Significance Index: 18.3500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1324
    Cell Significance Index: 1.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0872
    Cell Significance Index: 1.8900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0601
    Cell Significance Index: 11.9200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0395
    Cell Significance Index: 5.0700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0268
    Cell Significance Index: 0.9400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0256
    Cell Significance Index: 17.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0209
    Cell Significance Index: 3.7600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0197
    Cell Significance Index: 0.3300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0107
    Cell Significance Index: 16.4300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0096
    Cell Significance Index: 0.2400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0048
    Cell Significance Index: 0.2500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0033
    Cell Significance Index: 6.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0021
    Cell Significance Index: -3.9000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0063
    Cell Significance Index: -4.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0064
    Cell Significance Index: -8.6700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0067
    Cell Significance Index: -0.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0081
    Cell Significance Index: -0.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0089
    Cell Significance Index: -5.6600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0119
    Cell Significance Index: -4.2900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0127
    Cell Significance Index: -0.2700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0131
    Cell Significance Index: -9.5800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0131
    Cell Significance Index: -9.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0146
    Cell Significance Index: -2.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0149
    Cell Significance Index: -6.6000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0155
    Cell Significance Index: -8.7400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0170
    Cell Significance Index: -7.7200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0217
    Cell Significance Index: -13.5500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0222
    Cell Significance Index: -2.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0248
    Cell Significance Index: -2.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0287
    Cell Significance Index: -8.2700
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0309
    Cell Significance Index: -0.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0328
    Cell Significance Index: -6.5700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0372
    Cell Significance Index: -0.9500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0389
    Cell Significance Index: -4.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0403
    Cell Significance Index: -5.8600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0412
    Cell Significance Index: -2.5300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0573
    Cell Significance Index: -12.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0641
    Cell Significance Index: -3.6000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0653
    Cell Significance Index: -4.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0687
    Cell Significance Index: -8.8800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0800
    Cell Significance Index: -2.7800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0879
    Cell Significance Index: -9.1500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0979
    Cell Significance Index: -4.6000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0988
    Cell Significance Index: -2.7600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1003
    Cell Significance Index: -6.1500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1012
    Cell Significance Index: -7.1600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1030
    Cell Significance Index: -5.4100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1136
    Cell Significance Index: -5.7400
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.1160
    Cell Significance Index: -1.6100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1211
    Cell Significance Index: -9.5900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1255
    Cell Significance Index: -9.6300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1297
    Cell Significance Index: -3.4100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1369
    Cell Significance Index: -1.1500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1458
    Cell Significance Index: -6.8000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1514
    Cell Significance Index: -10.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1518
    Cell Significance Index: -9.5700
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1618
    Cell Significance Index: -1.3800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1662
    Cell Significance Index: -2.5100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1710
    Cell Significance Index: -3.5800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1770
    Cell Significance Index: -4.0900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2008
    Cell Significance Index: -2.8800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2166
    Cell Significance Index: -8.8800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2269
    Cell Significance Index: -6.5100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.2295
    Cell Significance Index: -3.5500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2297
    Cell Significance Index: -10.1600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2350
    Cell Significance Index: -2.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2355
    Cell Significance Index: -6.4100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2400
    Cell Significance Index: -7.0700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2435
    Cell Significance Index: -1.6500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2587
    Cell Significance Index: -6.6500
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2589
    Cell Significance Index: -3.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2682
    Cell Significance Index: -10.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** DOK1 is a cytoplasmic protein that belongs to the docking protein family. It is characterized by its ability to bind to specific tyrosine kinases, such as PTK6, and facilitate the recruitment of downstream effectors. DOK1 is highly expressed in cells involved in immune responses, including macrophages and monocytes, where it plays a crucial role in the regulation of inflammatory responses. Additionally, DOK1 is also expressed in neurons, where it is involved in the regulation of axon guidance and neuronal development. **Pathways and Functions** DOK1 is involved in various signaling pathways, including: 1. **Tyrosine Kinase Signaling**: DOK1 binds to tyrosine kinases, such as PTK6, and facilitates the recruitment of downstream effectors, including Akt1 and Dok1 itself. 2. **MAPK Cascade**: DOK1 is involved in the regulation of the MAPK cascade, a key signaling pathway involved in cell proliferation, differentiation, and survival. 3. **Ras Protein Signaling**: DOK1 is also involved in Ras protein signaling, a pathway involved in cell growth and differentiation. 4. **Ret Signaling**: DOK1 is expressed in retinal cells and is involved in the regulation of retinal development and function. 5. **Immune Response**: DOK1 is highly expressed in immune cells, where it plays a crucial role in the regulation of inflammatory responses. **Functions** The functions of DOK1 can be summarized as follows: 1. **Cell Signaling**: DOK1 facilitates the interaction between signaling molecules and downstream effectors, regulating various cellular processes, including cell growth, differentiation, and survival. 2. **Immune Response**: DOK1 is involved in the regulation of inflammatory responses, particularly in macrophages and monocytes. 3. **Neuronal Development**: DOK1 is expressed in retinal cells and is involved in the regulation of axon guidance and neuronal development. 4. **Epithelial Function**: DOK1 is also expressed in epithelial cells, where it plays a role in maintaining epithelial integrity and function. **Clinical Significance** DOK1 has been implicated in various diseases, including: 1. **Autoimmune Disorders**: DOK1 has been shown to be overexpressed in autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer**: DOK1 has been implicated in the development and progression of various cancers, including breast cancer and colon cancer. 3. **Neurological Disorders**: DOK1 has been shown to be involved in the regulation of neuronal development and function, and has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, DOK1 is a critical gene involved in various cellular processes, including signaling pathways, cell development, and immune responses. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the functions and clinical significance of this gene.

Genular Protein ID: 2705587523

Symbol: DOK1_HUMAN

Name: Docking protein 1

UniProtKB Accession Codes:

Q99704 O43204 Q53TY2 Q9UHG6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 5 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SASBDB 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9008160

Title: p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells.

PubMed ID: 9008160

DOI: 10.1016/s0092-8674(00)81840-1

PubMed ID: 10940083

Title: Molecular cloning of a truncated p62Dok1 isoform, p22Dokdel.

PubMed ID: 10940083

DOI: 10.1046/j.1365-2370.2000.00203.x

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11551902

Title: Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.

PubMed ID: 11551902

DOI: 10.1074/jbc.m102116200

PubMed ID: 12595900

Title: DOK4 and DOK5: new Dok-related genes expressed in human T cells.

PubMed ID: 12595900

DOI: 10.1038/sj.gene.6363891

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19481542

Title: Targeted mass spectrometric analysis of N-terminally truncated isoforms generated via alternative translation initiation.

PubMed ID: 19481542

DOI: 10.1016/j.febslet.2009.05.042

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23822091

Title: The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate Dok1.

PubMed ID: 23822091

DOI: 10.1111/febs.12420

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 18156175

Title: An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.

PubMed ID: 18156175

DOI: 10.1074/jbc.m709435200

Sequence Information:

  • Length: 481
  • Mass: 52392
  • Checksum: E9D947831244BA6C
  • Sequence:
    • MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL 
DCKVIRLAEC VSVAPVTVET PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP 
KGSWTLAPTD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVEA 
ERLTLLTVGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND 
IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL 
DSLRIAPCPS QDSLYSDPLD STSAQAGEGV QRKKPLYWDL YEHAQQQLLK AKLTDPKEDP 
IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL 
LAPKPQGPAF PEPGTATGSG IKSHNSALYS QVQKSGASGS WDCGLSRVGT DKTGVKSEGS 
T

Genular Protein ID: 101179555

Symbol: B4DJN1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DJN1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 470
  • Mass: 51068
  • Checksum: F4DCD9AB4E6F0FA3
  • Sequence:
    • MPNLIRASSG WRKTWAVLYP ASPHGVARLE FFDHKGSSSG GGRGSSRRLD CKVIRLAECV 
SVAPVTVETP PEPGATAFRL DTAQRSHLLA ADAPSSAAWV QTLCRNAFPK GSWTLAPTDN 
PPKLSALEML ENSLYSPTWE GSQFWVTVQR TEAAERCGLH GSYVLRVEAE RLTLLTVGAQ 
SQILEPLLSW PYTLLRRYGR DKVMFSFEAG RRCPSGPGTF TFQTAQGNDI FQAVETAIHR 
QKAQGKAGQG HDVLRADSHE GEVAEGKLPS PPGPQELLDS PPALYAEPLD SLRIAPCPSQ 
DSLYSDPLDS TSAQAGEGVQ RKKPLYWDLY EHAQQQLLKA KLTDPKEDPI YDEPEGLAPV 
PPQGLYDLPR EPKDAWWCQA RVKEEGYELP YNPATDDYAV PPPRSTKPLL APKPQGPAFP 
EPGTATGSGI KSHNSALYSQ VQKSGASGSW DCGLSRVGTD KTGVKSEGST

Genular Protein ID: 447885415

Symbol: Q2TA81_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2TA81

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 GO 5 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 3 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 267
  • Mass: 28752
  • Checksum: 02B8B42C740979F0
  • Sequence:
    • MFSFEAGRRC PSGPGTFTFQ TAQGNDIFQA VETAIHRQKA QGKAGQGHDV LRADSHEGEV 
AEGKLPSPPG PQELLDSPPA LYAEPLDSLR IAPCPSQDSL YSDPLDSTSA QAGEGVQRKK 
PLYWDLYEHA QQQLLKAKLT DPKEDPIYDE PEGLAPVPPQ GLYDLPREPK DAWWCQARVK 
EEGYELPYNP ATDDYAVPPP RSTKPLLAPK PQGPAFPEPG TATGSGIKSH NSALYSQVQK 
SGASGSWDCG LSRVGTDKTG VKSEGST

Genular Protein ID: 247488736

Symbol: Q14CB2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q14CB2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 267
  • Mass: 28683
  • Checksum: 02B8B44704097905
  • Sequence:
    • MFSFEAGRSC PSGPGTFTFQ TAQGNDIFQA VETAIHRQKA QGKAGQGHDV LRADSHEGEV 
AEGKLPSPPG PQELLDSPPA LYAEPLDSLR IAPCPSQDSL YSDPLDSTSA QAGEGVQRKK 
PLYWDLYEHA QQQLLKAKLT DPKEDPIYDE PEGLAPVPPQ GLYDLPREPK DAWWCQARVK 
EEGYELPYNP ATDDYAVPPP RSTKPLLAPK PQGPAFPEPG TATGSGIKSH NSALYSQVQK 
SGASGSWDCG LSRVGTDKTG VKSEGST

Genular Protein ID: 3407105697

Symbol: B3KP83_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KP83

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 5 SAM 1 SMART 3 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 481
  • Mass: 52408
  • Checksum: 60A4C8D9A876C1DE
  • Sequence:
    • MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL 
DCKVIRLAEC VSVALVTVET PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP 
KGSWTLAPTD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVEA 
ERLTLLTVGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND 
IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL 
DSLRIAPCPS QDSLYSDPLD STSAQAGEGV QRKKPLYWDL YEHAQQQLLK AKLTDPKEDP 
IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL 
LAPKPQGPAF PEPGTATGSG IKSHNSALYS QVQKSGASGS WDCGLSRVGT DKTGVKSEGS 
T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.