Details for: DOK1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 1.95
Marker Score: 16463 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.17
Marker Score: 1457 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71763 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47987 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30403 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.97
Marker Score: 2427 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.96
Marker Score: 2714 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2405 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 483 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 437 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.92
Marker Score: 506 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5216 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2719 - Cell Name: germ cell (CL0000586)
Fold Change: 0.88
Marker Score: 1533 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5262 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.82
Marker Score: 20950 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.75
Marker Score: 1225 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.73
Marker Score: 3008 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 374 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.72
Marker Score: 547 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.71
Marker Score: 284 - Cell Name: brush cell (CL0002204)
Fold Change: 0.7
Marker Score: 636 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.69
Marker Score: 4383 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.68
Marker Score: 2853 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.67
Marker Score: 1304 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.66
Marker Score: 37038 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.65
Marker Score: 524 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.65
Marker Score: 167 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.65
Marker Score: 324 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 0.64
Marker Score: 205 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.62
Marker Score: 1258 - Cell Name: blood cell (CL0000081)
Fold Change: 0.61
Marker Score: 7041 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.58
Marker Score: 202 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.57
Marker Score: 580 - Cell Name: promyelocyte (CL0000836)
Fold Change: 0.57
Marker Score: 280 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.57
Marker Score: 683 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.56
Marker Score: 293 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.55
Marker Score: 176 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 430 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.52
Marker Score: 1542 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.52
Marker Score: 517 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 0.51
Marker Score: 1328 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 0.5
Marker Score: 364 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.49
Marker Score: 2973 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.49
Marker Score: 130 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.49
Marker Score: 155 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.49
Marker Score: 203 - Cell Name: lung macrophage (CL1001603)
Fold Change: 0.47
Marker Score: 539 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.46
Marker Score: 314 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.44
Marker Score: 282 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.44
Marker Score: 211 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.44
Marker Score: 4461 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 0.44
Marker Score: 2648 - Cell Name: basophil (CL0000767)
Fold Change: 0.44
Marker Score: 207 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.43
Marker Score: 291 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.43
Marker Score: 685 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 0.43
Marker Score: 178 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 0.42
Marker Score: 170 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.42
Marker Score: 275 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.41
Marker Score: 180 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.41
Marker Score: 515.5 - Cell Name: Langerhans cell (CL0000453)
Fold Change: 0.41
Marker Score: 123 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.41
Marker Score: 271 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.4
Marker Score: 198 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.4
Marker Score: 78 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.39
Marker Score: 717 - Cell Name: neural cell (CL0002319)
Fold Change: 0.39
Marker Score: 188 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 0.39
Marker Score: 366 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.39
Marker Score: 559 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.39
Marker Score: 375 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.38
Marker Score: 83 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.38
Marker Score: 77 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.38
Marker Score: 382 - Cell Name: myelocyte (CL0002193)
Fold Change: 0.38
Marker Score: 163.5 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.38
Marker Score: 370 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.38
Marker Score: 96 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.38
Marker Score: 184 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.37
Marker Score: 154 - Cell Name: Unknown (CL0000548)
Fold Change: 0.37
Marker Score: 268 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.36
Marker Score: 998 - Cell Name: platelet (CL0000233)
Fold Change: 0.36
Marker Score: 162 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.35
Marker Score: 157 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.35
Marker Score: 223 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.35
Marker Score: 265 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.35
Marker Score: 158 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.35
Marker Score: 77 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.35
Marker Score: 955.5 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.35
Marker Score: 211 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 0.35
Marker Score: 252 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.35
Marker Score: 110 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.35
Marker Score: 5426 - Cell Name: memory B cell (CL0000787)
Fold Change: 0.35
Marker Score: 262 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.34
Marker Score: 119 - Cell Name: oocyte (CL0000023)
Fold Change: 0.34
Marker Score: 85 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 0.34
Marker Score: 822 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.34
Marker Score: 106 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.34
Marker Score: 140 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.34
Marker Score: 79 - Cell Name: pre-conventional dendritic cell (CL0002010)
Fold Change: 0.33
Marker Score: 99
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Other Information
Genular Protein ID: 2705587523
Symbol: DOK1_HUMAN
Name: Docking protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9008160
Title: p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells.
PubMed ID: 9008160
PubMed ID: 10940083
Title: Molecular cloning of a truncated p62Dok1 isoform, p22Dokdel.
PubMed ID: 10940083
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11551902
Title: Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.
PubMed ID: 11551902
PubMed ID: 12595900
Title: DOK4 and DOK5: new Dok-related genes expressed in human T cells.
PubMed ID: 12595900
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19481542
Title: Targeted mass spectrometric analysis of N-terminally truncated isoforms generated via alternative translation initiation.
PubMed ID: 19481542
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23822091
Title: The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate Dok1.
PubMed ID: 23822091
DOI: 10.1111/febs.12420
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 18156175
Title: An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.
PubMed ID: 18156175
Sequence Information:
- Length: 481
- Mass: 52392
- Checksum: E9D947831244BA6C
- Sequence:
MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL DCKVIRLAEC VSVAPVTVET PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP KGSWTLAPTD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVEA ERLTLLTVGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL DSLRIAPCPS QDSLYSDPLD STSAQAGEGV QRKKPLYWDL YEHAQQQLLK AKLTDPKEDP IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL LAPKPQGPAF PEPGTATGSG IKSHNSALYS QVQKSGASGS WDCGLSRVGT DKTGVKSEGS T
Genular Protein ID: 247488736
Symbol: Q14CB2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 267
- Mass: 28683
- Checksum: 02B8B44704097905
- Sequence:
MFSFEAGRSC PSGPGTFTFQ TAQGNDIFQA VETAIHRQKA QGKAGQGHDV LRADSHEGEV AEGKLPSPPG PQELLDSPPA LYAEPLDSLR IAPCPSQDSL YSDPLDSTSA QAGEGVQRKK PLYWDLYEHA QQQLLKAKLT DPKEDPIYDE PEGLAPVPPQ GLYDLPREPK DAWWCQARVK EEGYELPYNP ATDDYAVPPP RSTKPLLAPK PQGPAFPEPG TATGSGIKSH NSALYSQVQK SGASGSWDCG LSRVGTDKTG VKSEGST
Genular Protein ID: 447885415
Symbol: Q2TA81_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 267
- Mass: 28752
- Checksum: 02B8B42C740979F0
- Sequence:
MFSFEAGRRC PSGPGTFTFQ TAQGNDIFQA VETAIHRQKA QGKAGQGHDV LRADSHEGEV AEGKLPSPPG PQELLDSPPA LYAEPLDSLR IAPCPSQDSL YSDPLDSTSA QAGEGVQRKK PLYWDLYEHA QQQLLKAKLT DPKEDPIYDE PEGLAPVPPQ GLYDLPREPK DAWWCQARVK EEGYELPYNP ATDDYAVPPP RSTKPLLAPK PQGPAFPEPG TATGSGIKSH NSALYSQVQK SGASGSWDCG LSRVGTDKTG VKSEGST
Genular Protein ID: 101179555
Symbol: B4DJN1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 470
- Mass: 51068
- Checksum: F4DCD9AB4E6F0FA3
- Sequence:
MPNLIRASSG WRKTWAVLYP ASPHGVARLE FFDHKGSSSG GGRGSSRRLD CKVIRLAECV SVAPVTVETP PEPGATAFRL DTAQRSHLLA ADAPSSAAWV QTLCRNAFPK GSWTLAPTDN PPKLSALEML ENSLYSPTWE GSQFWVTVQR TEAAERCGLH GSYVLRVEAE RLTLLTVGAQ SQILEPLLSW PYTLLRRYGR DKVMFSFEAG RRCPSGPGTF TFQTAQGNDI FQAVETAIHR QKAQGKAGQG HDVLRADSHE GEVAEGKLPS PPGPQELLDS PPALYAEPLD SLRIAPCPSQ DSLYSDPLDS TSAQAGEGVQ RKKPLYWDLY EHAQQQLLKA KLTDPKEDPI YDEPEGLAPV PPQGLYDLPR EPKDAWWCQA RVKEEGYELP YNPATDDYAV PPPRSTKPLL APKPQGPAFP EPGTATGSGI KSHNSALYSQ VQKSGASGSW DCGLSRVGTD KTGVKSEGST
Genular Protein ID: 3407105697
Symbol: B3KP83_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 481
- Mass: 52408
- Checksum: 60A4C8D9A876C1DE
- Sequence:
MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL DCKVIRLAEC VSVALVTVET PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP KGSWTLAPTD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVEA ERLTLLTVGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL DSLRIAPCPS QDSLYSDPLD STSAQAGEGV QRKKPLYWDL YEHAQQQLLK AKLTDPKEDP IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL LAPKPQGPAF PEPGTATGSG IKSHNSALYS QVQKSGASGS WDCGLSRVGT DKTGVKSEGS T
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.