Details for: EIF5
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 3.66
Marker Score: 2,865 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 3.45
Marker Score: 2,943 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 3.34
Marker Score: 3,570 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.09
Marker Score: 105,153 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 2.94
Marker Score: 3,556 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 2.85
Marker Score: 2,160 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 2.73
Marker Score: 2,694 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.69
Marker Score: 7,543 - Cell Name: granulocyte (CL0000094)
Fold Change: 2.67
Marker Score: 1,195 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.65
Marker Score: 1,105 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.63
Marker Score: 2,063 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.62
Marker Score: 4,300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.6
Marker Score: 6,361 - Cell Name: oogonial cell (CL0000024)
Fold Change: 2.59
Marker Score: 3,729 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 2.56
Marker Score: 2,155 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.55
Marker Score: 610 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 2.49
Marker Score: 1,503 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.44
Marker Score: 84,685 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 2.42
Marker Score: 5,080 - Cell Name: mature T cell (CL0002419)
Fold Change: 2.4
Marker Score: 23,769 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.39
Marker Score: 133,472 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 2.38
Marker Score: 2,584 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 2.37
Marker Score: 1,186 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.37
Marker Score: 24,056 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 2.37
Marker Score: 18,517 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 2.36
Marker Score: 963 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.35
Marker Score: 4,693 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 2.34
Marker Score: 123,977 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 2.33
Marker Score: 20,041 - Cell Name: kidney loop of Henle epithelial cell (CL1000909)
Fold Change: 2.32
Marker Score: 1,457 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 2.32
Marker Score: 17,256 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 2.31
Marker Score: 537 - Cell Name: blood cell (CL0000081)
Fold Change: 2.31
Marker Score: 26,797 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.3
Marker Score: 4,681 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 2.3
Marker Score: 814 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 2.29
Marker Score: 1,558 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 2.28
Marker Score: 30,078 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 2.28
Marker Score: 2,133 - Cell Name: adventitial cell (CL0002503)
Fold Change: 2.27
Marker Score: 561 - Cell Name: hepatocyte (CL0000182)
Fold Change: 2.27
Marker Score: 1,548 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.27
Marker Score: 8,738 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 2.27
Marker Score: 8,390 - Cell Name: memory B cell (CL0000787)
Fold Change: 2.26
Marker Score: 1,712 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 2.26
Marker Score: 1,026 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 2.25
Marker Score: 2,124 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 2.25
Marker Score: 697 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.25
Marker Score: 1,281 - Cell Name: pro-B cell (CL0000826)
Fold Change: 2.24
Marker Score: 2,161 - Cell Name: supporting cell (CL0000630)
Fold Change: 2.23
Marker Score: 4,198 - Cell Name: endothelial cell (CL0000115)
Fold Change: 2.23
Marker Score: 2,001 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 2.23
Marker Score: 3,885 - Cell Name: IgA plasma cell (CL0000987)
Fold Change: 2.22
Marker Score: 1,889 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 2.22
Marker Score: 587 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 2.21
Marker Score: 19,227 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 2.21
Marker Score: 1,270 - Cell Name: theca cell (CL0000503)
Fold Change: 2.21
Marker Score: 1,580 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.2
Marker Score: 2,654 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 2.19
Marker Score: 1,005 - Cell Name: basal cell (CL0000646)
Fold Change: 2.19
Marker Score: 2,825 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 2.19
Marker Score: 1,380 - Cell Name: ciliated cell (CL0000064)
Fold Change: 2.18
Marker Score: 7,511 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 2.17
Marker Score: 3,078 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 2.17
Marker Score: 4,227 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 2.17
Marker Score: 14,107 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.17
Marker Score: 4,521 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.16
Marker Score: 2,476 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.16
Marker Score: 55,305 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 2.15
Marker Score: 1,827 - Cell Name: group 3 innate lymphoid cell (CL0001071)
Fold Change: 2.15
Marker Score: 904 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.15
Marker Score: 3,169 - Cell Name: dendritic cell (CL0000451)
Fold Change: 2.15
Marker Score: 1,475 - Cell Name: erythroid lineage cell (CL0000764)
Fold Change: 2.15
Marker Score: 1,072 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 2.15
Marker Score: 1,429 - Cell Name: stromal cell (CL0000499)
Fold Change: 2.15
Marker Score: 2,514 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.13
Marker Score: 4,853 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 2.13
Marker Score: 6,709 - Cell Name: leukocyte (CL0000738)
Fold Change: 2.12
Marker Score: 1,214 - Cell Name: epidermal cell (CL0000362)
Fold Change: 2.11
Marker Score: 594 - Cell Name: immature B cell (CL0000816)
Fold Change: 2.11
Marker Score: 1,400 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 2.11
Marker Score: 1,092 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 2.11
Marker Score: 555 - Cell Name: malignant cell (CL0001064)
Fold Change: 2.11
Marker Score: 28,329 - Cell Name: Mueller cell (CL0000636)
Fold Change: 2.11
Marker Score: 2,923 - Cell Name: ependymal cell (CL0000065)
Fold Change: 2.11
Marker Score: 735 - Cell Name: naive B cell (CL0000788)
Fold Change: 2.11
Marker Score: 1,880 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 2.1
Marker Score: 815 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 2.1
Marker Score: 5,490 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 2.09
Marker Score: 597 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 2.09
Marker Score: 422 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 2.09
Marker Score: 588 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.09
Marker Score: 6,552 - Cell Name: starburst amacrine cell (CL0004232)
Fold Change: 2.08
Marker Score: 591 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.08
Marker Score: 23,397 - Cell Name: chondrocyte (CL0000138)
Fold Change: 2.08
Marker Score: 935 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 2.08
Marker Score: 2,166 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 2.07
Marker Score: 3,676 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.07
Marker Score: 18,198 - Cell Name: Unknown (CL0000548)
Fold Change: 2.07
Marker Score: 1,509 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.07
Marker Score: 6,138 - Cell Name: tracheobronchial goblet cell (CL0019003)
Fold Change: 2.07
Marker Score: 567
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1835800574
Symbol: IF5_HUMAN
Name: Eukaryotic translation initiation factor 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8663286
Title: Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5).
PubMed ID: 8663286
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11166181
Title: Eukaryotic translation initiation factor 5 (eIF5) acts as a classical GTPase-activator protein.
PubMed ID: 11166181
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21745818
Title: Mechanisms of translational regulation by a human eIF5-mimic protein.
PubMed ID: 21745818
DOI: 10.1093/nar/gkr339
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22813744
Title: The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2beta.
PubMed ID: 22813744
PubMed ID: 24319994
Title: The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes.
PubMed ID: 24319994
DOI: 10.1021/bi4009775
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24658146
Title: Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin.
PubMed ID: 24658146
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 30211544
Title: Human eIF5 and eIF1A compete for binding to eIF5B.
PubMed ID: 30211544
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 431
- Mass: 49223
- Checksum: C6CCC3A255F9B9BC
- Sequence:
MSVNVNRSVS DQFYRYKMPR LIAKVEGKGN GIKTVIVNMV DVAKALNRPP TYPTKYFGCE LGAQTQFDVK NDRYIVNGSH EANKLQDMLD GFIKKFVLCP ECENPETDLH VNPKKQTIGN SCKACGYRGM LDTHHKLCTF ILKNPPENSD SGTGKKEKEK KNRKGKDKEN GSVSSSETPP PPPPPNEINP PPHTMEEEED DDWGEDTTEE AQRRRMDEIS DHAKVLTLSD DLERTIEERV NILFDFVKKK KEEGVIDSSD KEIVAEAERL DVKAMGPLVL TEVLFNEKIR EQIKKYRRHF LRFCHNNKKA QRYLLHGLEC VVAMHQAQLI SKIPHILKEM YDADLLEEEV IISWSEKASK KYVSKELAKE IRVKAEPFIK WLKEAEEESS GGEEEDEDEN IEVVYSKAAS VPKVETVKSD NKDDDIDIDA I
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.