Details for: EPHB2

Gene ID: 2048

Symbol: EPHB2

Ensembl ID: ENSG00000133216

Description: EPH receptor B2

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.6
    Marker Score: 121684
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.92
    Marker Score: 15669
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.05
    Marker Score: 1149
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2
    Marker Score: 29841
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.82
    Marker Score: 9531
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.73
    Marker Score: 13047
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.71
    Marker Score: 17658
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.69
    Marker Score: 3197.5
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.68
    Marker Score: 1266
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.62
    Marker Score: 3302
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.62
    Marker Score: 623
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.61
    Marker Score: 3698
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.58
    Marker Score: 15014
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.55
    Marker Score: 95612
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.49
    Marker Score: 3531
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.43
    Marker Score: 13460
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.41
    Marker Score: 5460
  • Cell Name: interneuron (CL0000099)
    Fold Change: 1.38
    Marker Score: 630
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.38
    Marker Score: 50827
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.38
    Marker Score: 2123
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.35
    Marker Score: 858
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.33
    Marker Score: 11425
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.3
    Marker Score: 3113
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.24
    Marker Score: 723
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 1.24
    Marker Score: 3549
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.23
    Marker Score: 24553
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.2
    Marker Score: 450
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.19
    Marker Score: 18696
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.18
    Marker Score: 621
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.15
    Marker Score: 43557
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.12
    Marker Score: 354
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.11
    Marker Score: 8498
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.08
    Marker Score: 4397
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71781
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48005
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30405
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.97
    Marker Score: 4500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 501
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 455
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2411
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.94
    Marker Score: 1531
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5319
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.92
    Marker Score: 297
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2733
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.9
    Marker Score: 445
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.89
    Marker Score: 320
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5296
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.86
    Marker Score: 596
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.84
    Marker Score: 351
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.78
    Marker Score: 1317
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.78
    Marker Score: 595
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.77
    Marker Score: 3220.5
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.77
    Marker Score: 3191
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 0.77
    Marker Score: 2566
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.76
    Marker Score: 305
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.76
    Marker Score: 457
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 390
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.75
    Marker Score: 360
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.73
    Marker Score: 2073
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.73
    Marker Score: 464
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.71
    Marker Score: 648
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.71
    Marker Score: 2932
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.71
    Marker Score: 611
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.7
    Marker Score: 464
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.7
    Marker Score: 875
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 177
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.66
    Marker Score: 717
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.66
    Marker Score: 1783
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.65
    Marker Score: 1527
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.64
    Marker Score: 206
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.64
    Marker Score: 4145
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.63
    Marker Score: 759
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.58
    Marker Score: 408
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.58
    Marker Score: 575
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 0.57
    Marker Score: 173
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 148
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.55
    Marker Score: 574
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 0.55
    Marker Score: 529
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 439
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.54
    Marker Score: 195
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.54
    Marker Score: 126
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.53
    Marker Score: 5364
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.53
    Marker Score: 1672
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.53
    Marker Score: 751
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.51
    Marker Score: 235
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.51
    Marker Score: 281
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.51
    Marker Score: 243
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.51
    Marker Score: 132
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 0.5
    Marker Score: 708
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.49
    Marker Score: 2056.5
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.48
    Marker Score: 239
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.48
    Marker Score: 211
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.47
    Marker Score: 195
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.47
    Marker Score: 293
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.46
    Marker Score: 357
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.46
    Marker Score: 2744
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.46
    Marker Score: 236
  • Cell Name: epithelial fate stem cell (CL0000036)
    Fold Change: 0.45
    Marker Score: 130
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.45
    Marker Score: 767
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 0.45
    Marker Score: 150

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Other Information

**Key characteristics:** - EPHB2 is a single-pass transmembrane protein with a molecular weight of approximately 140 kDa. - It is a member of the Eph family of cell surface receptors, which are characterized by a conserved extracellular domain and a transmembrane domain. - EPHB2 is a ligand for Ephrin-A, a secreted extracellular protein that is expressed in the developing nervous system. **Pathways and functions:** - EPHB2 is a key receptor for Ephrin-A, which is expressed on neurons and glial cells. - Ephrin-A and EPHB2 bind to each other, which triggers a signaling cascade that leads to the phosphorylation of EPHB2 and the subsequent activation of downstream signaling pathways. - These pathways include the ERK/MAPK pathway, the PI3K/Akt pathway, and the Wnt/β-catenin pathway. - Activation of these pathways leads to a variety of cellular responses, including cell migration, proliferation, and survival. **Clinical significance:** - Mutations in EPHB2 have been linked to a number of neurodevelopmental disorders, including autism, schizophrenia, and Alzheimer's disease. - EPHB2 is a potential therapeutic target for these disorders, as inhibitors of EphB2 have been shown to be effective in preventing neurodevelopmental defects. **Additional information:** - EPHB2 is a highly conserved protein, with a similar protein found in mice. - It is expressed in a variety of brain regions, including the cerebral cortex, cerebellum, and hippocampus. - EPHB2 is a key regulator of neural tube closure and brain development.

Genular Protein ID: 353326526

Symbol: EPHB2_HUMAN

Name: Ephrin type-B receptor 2

UniProtKB Accession Codes:

P29323 O43477 Q5T0U6 Q5T0U7 Q5T0U8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 5 CPTAC 2 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 EC 2 EMBL 10 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 80 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 19 KEGG 1 MANE-Select 1 MIM 6 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 5 PIR 2 PIRSF 1 PRINTS 2 PRO 1 PROSITE 8 PROSITE-ProRule 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 5 RefSeq 3 Rhea 3 SAM 1 SIGNOR 1 SMART 5 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8033077

Title: Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors.

PubMed ID: 8033077

PubMed ID: 8589679

Title: Molecular characterization and chromosomal localization of DRT (EPHT3): a developmentally regulated human protein-tyrosine kinase gene of the EPH family.

PubMed ID: 8589679

DOI: 10.1093/hmg/4.11.2033

PubMed ID: 9696046

Title: A variant transcript encoding an isoform of the human protein tyrosine kinase EPHB2 is generated by alternative splicing and alternative use of polyadenylation signals.

PubMed ID: 9696046

DOI: 10.1038/sj.onc.1201960

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 7898931

Title: cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

PubMed ID: 7898931

PubMed ID: 7601466

Title: Identification of the human ERK gene as a putative receptor tyrosine kinase and its chromosomal localization to 1p36.1: a comparative mapping of human, mouse, and rat chromosomes.

PubMed ID: 7601466

DOI: 10.1016/0888-7543(95)80224-a

PubMed ID: 7688222

Title: Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer.

PubMed ID: 7688222

DOI: 10.1006/bbrc.1993.1878

PubMed ID: 1648701

Title: eek and erk, new members of the eph subclass of receptor protein-tyrosine kinases.

PubMed ID: 1648701

PubMed ID: 9267020

Title: Unified nomenclature for Eph family receptors and their ligands, the ephrins.

PubMed ID: 9267020

DOI: 10.1016/s0092-8674(00)80500-0

PubMed ID: 10508479

Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.

PubMed ID: 10508479

DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 28931592

Title: Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.

PubMed ID: 28931592

DOI: 10.1091/mbc.e17-07-0450

PubMed ID: 33280498

Title: RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.

PubMed ID: 33280498

DOI: 10.1080/15548627.2020.1851496

PubMed ID: 9933164

Title: Oligomeric structure of the human EphB2 receptor SAM domain.

PubMed ID: 9933164

DOI: 10.1126/science.283.5403.833

PubMed ID: 17897949

Title: Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.

PubMed ID: 17897949

DOI: 10.1074/jbc.m706340200

PubMed ID: 15300251

Title: Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.

PubMed ID: 15300251

DOI: 10.1038/ng1408

PubMed ID: 16155194

Title: A common nonsense mutation in EphB2 is associated with prostate cancer risk in African American men with a positive family history.

PubMed ID: 16155194

DOI: 10.1136/jmg.2005.035790

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 30213874

Title: A mutation of the human EPHB2 gene leads to a major platelet functional defect.

PubMed ID: 30213874

DOI: 10.1182/blood-2018-04-845644

Sequence Information:

  • Length: 1055
  • Mass: 117493
  • Checksum: 4F8BFEDC45986483
  • Sequence:
    • MALRRLGAAL LLLPLLAAVE ETLMDSTTAT AELGWMVHPP SGWEEVSGYD ENMNTIRTYQ 
VCNVFESSQN NWLRTKFIRR RGAHRIHVEM KFSVRDCSSI PSVPGSCKET FNLYYYEADF 
DSATKTFPNW MENPWVKVDT IAADESFSQV DLGGRVMKIN TEVRSFGPVS RSGFYLAFQD 
YGGCMSLIAV RVFYRKCPRI IQNGAIFQET LSGAESTSLV AARGSCIANA EEVDVPIKLY 
CNGDGEWLVP IGRCMCKAGF EAVENGTVCR GCPSGTFKAN QGDEACTHCP INSRTTSEGA 
TNCVCRNGYY RADLDPLDMP CTTIPSAPQA VISSVNETSL MLEWTPPRDS GGREDLVYNI 
ICKSCGSGRG ACTRCGDNVQ YAPRQLGLTE PRIYISDLLA HTQYTFEIQA VNGVTDQSPF 
SPQFASVNIT TNQAAPSAVS IMHQVSRTVD SITLSWSQPD QPNGVILDYE LQYYEKELSE 
YNATAIKSPT NTVTVQGLKA GAIYVFQVRA RTVAGYGRYS GKMYFQTMTE AEYQTSIQEK 
LPLIIGSSAA GLVFLIAVVV IAIVCNRRGF ERADSEYTDK LQHYTSGHMT PGMKIYIDPF 
TYEDPNEAVR EFAKEIDISC VKIEQVIGAG EFGEVCSGHL KLPGKREIFV AIKTLKSGYT 
EKQRRDFLSE ASIMGQFDHP NVIHLEGVVT KSTPVMIITE FMENGSLDSF LRQNDGQFTV 
IQLVGMLRGI AAGMKYLADM NYVHRDLAAR NILVNSNLVC KVSDFGLSRF LEDDTSDPTY 
TSALGGKIPI RWTAPEAIQY RKFTSASDVW SYGIVMWEVM SYGERPYWDM TNQDVINAIE 
QDYRLPPPMD CPSALHQLML DCWQKDRNHR PKFGQIVNTL DKMIRNPNSL KAMAPLSSGI 
NLPLLDRTIP DYTSFNTVDE WLEAIKMGQY KESFANAGFT SFDVVSQMMM EDILRVGVTL 
AGHQKKILNS IQVMRAQMNQ IQSVEGQPLA RRPRATGRTK RCQPRDVTKK TCNSNDGKKK 
GMGKKKTDPG RGREIQGIFF KEDSHKESND CSCGG

Genular Protein ID: 3612401510

Symbol: Q6NVW1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6NVW1

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 2 GO 4 Gene3D 4 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 9 KEGG 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 4 SAM 1 SMART 3 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

Sequence Information:

  • Length: 482
  • Mass: 53252
  • Checksum: 29086541708507B5
  • Sequence:
    • MALRRLGAAL LLLPLLAAVE ETLMDSTTAT AELGWMVHPP SGWEEVSGYD ENMNTIRTYQ 
VCNVFESSQN NWLRTKFIRR RGAHRIHVEM KFSVRDCSSI PSVPGSCKET FNLYYYEADF 
DSATKTFPNW MENPWVKVDT IAADESFSQV DLGGRVMKIN TEVRSFGPVS RSGFYLAFQD 
YGGCMSLIAV RVFYRKCPRI IQNGAIFQET LSGAESTSLV AARGSCIANA EEVDVPIKLY 
CNGDGEWLVP IGRCMCKAGF EAVENGTVCR GCPSGTFKAN QGDEACTHCP INSRTTSEGA 
TNCVCRNGYY RADLDPLDMP CTTIPSAPQA VISSVNETSL MLEWTPPRDS GGREDLVYNI 
ICKSCGSGRG ACTRCGDNVQ YAPRQLGLTE PRIYISDLLA HTQYTFEIQA VNGVTDQSPF 
SPQFASVNIT TNQAAPSAVS IMHQVSRTVD SITLSWSQPD QPNGVILDYE LQYYEKMKTQ 
RS

Genular Protein ID: 1505998436

Symbol: Q4LE53_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q4LE53

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 5 CTD 1 ChEBI 7 ChiTaRS 1 DNASU 1 EC 1 EMBL 2 GO 3 Gene3D 6 GenomeRNAi 1 InterPro 19 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 12 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 RefSeq 3 Rhea 3 SAM 2 SMART 5 SUPFAM 5

Sequence Information:

  • Length: 1004
  • Mass: 111512
  • Checksum: 0CBA9D22B278CA49
  • Sequence:
    • PGRPGPAAPR PEAPGSAAMA LRRLGAALLL LPLLAAVEET LMDSTTATAE LGWMVHPPSG 
WEEVSGYDEN MNTIRTYQVC NVFESSQNNW LRTKFIRRRG AHRIHVEMKF SVRDCSSIPS 
VPGSCKETFN LYYYEADFDS ATKTFPNWME NPWVKVDTIA ADESFSQVDL GGRVMKINTE 
VRSFGPVSRS GFYLAFQDYG GCMSLIAVRV FYRKCPRIIQ NGAIFQETLS GAESTSLVAA 
RGSCIANAEE VDVPIKLYCN GDGEWLVPIG RCMCKAGFEA VENGTVCRGC PSGTFKANQG 
DEACTHCPIN SRTTSEGATN CVCRNGYYRA DLDPLDMPCT TIPSAPQAVI SSVNETSLML 
EWTPPRDSGG REDLVYNIIC KSCGSGRGAC TRCGDNVQYA PRQLGLTEPR IYISDLLAHT 
QYTFEIQAVN GVTDQSPFSP QFASVNITTN QAAPSAVSIM HQVSRTVDSI TLSWSQPDQP 
NGVILDYELQ YYEKELSEYN ATAIKSPTNT VTVQGLKAGA IYVFQVRART VAGYGRYSGK 
MYFQTMTEAE YQTSIQEKLP LIIGSSAAGL VFLIAVVVIA IVCNRRGFER ADSEYTDKLQ 
HYTSGHMTPG MKIYIDPFTY EDPNEAVREF AKEIDISCVK IEQVIGAGEF GEVCSGHLKL 
PGKREIFVAI KTLKSGYTEK QRRDFLSEAS IMGQFDHPNV IHLEGVVTKS TPVMIITEFM 
ENGSLDSFLR QNDGQFTVIQ LVGMLRGIAA GMKYLADMNY VHRDLAARNI LVNSNLVCKV 
SDFGLSRFLE DDTSDPTYTS ALGGKIPIRW TAPEAIQYRK FTSASDVWSY GIVMWEVMSY 
GERPYWDMTN QDVINAIEQD YRLPPPMDCP SALHQLMLDC WQKDRNHRPK FGQIVNTLDK 
MIRNPNSLKA MAPLSSGINL PLLDRTIPDY TSFNTVDEWL EAIKMGQYKE SFANAGFTSF 
DVVSQMMMED ILRVGVTLAG HQKKILNSIQ VMRAQMNQIQ SVEV

Genular Protein ID: 2107416866

Symbol: B4DSE0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DSE0

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 5 CTD 1 ChEBI 7 DNASU 1 EC 1 EMBL 2 GO 3 Gene3D 6 GenomeRNAi 1 InterPro 19 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 12 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 RefSeq 1 Rhea 3 SAM 1 SMART 5 SUPFAM 5

Sequence Information:

  • Length: 928
  • Mass: 103510
  • Checksum: A7A32A8A82504910
  • Sequence:
    • MALRRLGAAL LLLPLLAAVE ETLMDSTTAT AELGWMVHPP SGWEEVSGYD ENMNTIRTYQ 
VCNVFESSQN NWLRTKFIRR RGAHRIHVEM KFSVRDCSSI PSVPGSCKET FNLYYYEADF 
DSATKTFPNW MENPWVKVDT IAADESFSQV DLGGRVMKIN TEVRSFGPVS RSGFYLAFQD 
YGGCMSLIAV RVFYRKCPRI IQNGAIFQET LSGAESTSLV AARGSCIANA EEVDVPIKLY 
CNGDGEWLVP IGRCMCKAGF EAVENGTVCR GCPSGTFKAN QGDEACTHCP INSRTTSEGA 
TNCVCRNGYY RADLDPLDMP CTTIPSAPQA VISSVNETSL MLEWTPPRDS GGREDLVYNI 
ICKSCGSGRG ACTRCGDNVQ YAPRQLGLTE PRIYISDLLA HTQYTFEIQA VNGVTDQSPF 
SPQFASVNIT TNQAAPSAVS IMHQVSRTVD SITLSWSQPD QPNGVILDYE LQYYEKELSE 
YNATAIKSPT NTVTVQGLKA GAIYVFQVRA RTVAGYGRYS GKMYFQTMTE VTPGMKIYID 
PFTYEDPNEA VREFAKEIDI SCVKIEQVIG AGEFGEVCSG HLKLPGKREI FVAIKTLKSG 
YTEKQRRDFL SEASIMGQFD HPNVIHLEGV VTKSTPVMII TEFMENGSLD SFLRQNDGQF 
TVIQLVGMLR GIAAGMKYLA DMNYVHRDLA ARNILVNSNL VCKVSDFGLS RFLEDDTSDP 
TYTSALGGKI PIRWTAPEAI QYRKFTSASD VWSYGIVMWE VMSYGERPYW DMTNQDVINA 
IEQDYRLPPP MDCPSALHQL MLDCWQKDRN HRPKFGQIVN TLDKMIRNPN SLKAMAPLSS 
GINLPLLDRT IPDYTSFNTV DEWLEAIKMG QYKESFANAG FTSFDVVSQM MMEDILRVGV 
TLTGHQKKIL NSIQVMRAQM NQIQSVEV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.