Details for: FANCA
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.12
Marker Score: 3325 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.01
Marker Score: 2059 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71783 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48008 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30404 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.97
Marker Score: 9214 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.96
Marker Score: 540 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.96
Marker Score: 2263 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.95
Marker Score: 491 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.95
Marker Score: 1147 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.95
Marker Score: 306 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2408 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.94
Marker Score: 445 - Cell Name: centroblast (CL0009112)
Fold Change: 0.94
Marker Score: 462 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.92
Marker Score: 555 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2724 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.89
Marker Score: 13975 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5035 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.88
Marker Score: 8284 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.88
Marker Score: 53839 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5295 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 312 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.86
Marker Score: 1326 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.83
Marker Score: 7171 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.82
Marker Score: 934 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.8
Marker Score: 691 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1264 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.75
Marker Score: 509 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.75
Marker Score: 561 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.74
Marker Score: 568 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.74
Marker Score: 2018.5 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.74
Marker Score: 381 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.73
Marker Score: 293 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.73
Marker Score: 5568 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.73
Marker Score: 965 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.72
Marker Score: 674 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.7
Marker Score: 464 - Cell Name: brush cell (CL0002204)
Fold Change: 0.69
Marker Score: 632 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.68
Marker Score: 2872 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 169 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.65
Marker Score: 584 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.62
Marker Score: 9324 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.61
Marker Score: 2367 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.61
Marker Score: 190 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.6
Marker Score: 642 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.57
Marker Score: 719 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.55
Marker Score: 792 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.53
Marker Score: 438 - Cell Name: germinal center B cell (CL0000844)
Fold Change: 0.52
Marker Score: 316 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.51
Marker Score: 2007 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.5
Marker Score: 856 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.49
Marker Score: 492 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.49
Marker Score: 129 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.49
Marker Score: 238 - Cell Name: Unknown (CL0000548)
Fold Change: 0.48
Marker Score: 353 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.47
Marker Score: 17818 - Cell Name: promyelocyte (CL0000836)
Fold Change: 0.47
Marker Score: 231 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.46
Marker Score: 1880 - Cell Name: interneuron (CL0000099)
Fold Change: 0.45
Marker Score: 207 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.45
Marker Score: 228 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.45
Marker Score: 938 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.44
Marker Score: 8688 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.43
Marker Score: 2614 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.43
Marker Score: 416 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.43
Marker Score: 205 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.42
Marker Score: 244 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.4
Marker Score: 14604 - Cell Name: B cell (CL0000236)
Fold Change: 0.39
Marker Score: 375 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.39
Marker Score: 164 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.39
Marker Score: 112 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.39
Marker Score: 193 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.39
Marker Score: 242 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.38
Marker Score: 244 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.38
Marker Score: 159 - Cell Name: oocyte (CL0000023)
Fold Change: 0.38
Marker Score: 93 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.37
Marker Score: 88 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.37
Marker Score: 262 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.37
Marker Score: 589 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.36
Marker Score: 98 - Cell Name: stem cell (CL0000034)
Fold Change: 0.36
Marker Score: 847 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.35
Marker Score: 595 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.35
Marker Score: 220 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.35
Marker Score: 132.5 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.35
Marker Score: 146 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.35
Marker Score: 111 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.35
Marker Score: 90 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.34
Marker Score: 322 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.34
Marker Score: 1414 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.34
Marker Score: 250 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.34
Marker Score: 797 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.33
Marker Score: 186 - Cell Name: neuron (CL0000540)
Fold Change: 0.33
Marker Score: 1330 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.32
Marker Score: 607 - Cell Name: natural killer cell (CL0000623)
Fold Change: 0.32
Marker Score: 415 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.32
Marker Score: 101 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.32
Marker Score: 3271 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.31
Marker Score: 326 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.31
Marker Score: 3024 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.3
Marker Score: 207
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Other Information
Genular Protein ID: 2876220884
Symbol: FANCA_HUMAN
Name: Fanconi anemia group A protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8896563
Title: Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA.
PubMed ID: 8896563
DOI: 10.1038/ng1196-320
PubMed ID: 9169126
Title: The genomic organization of the Fanconi anemia group A (FAA) gene.
PubMed ID: 9169126
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9721219
Title: Fine exon-intron structure of the Fanconi anemia group A (FAA) gene and characterization of two genomic deletions.
PubMed ID: 9721219
PubMed ID: 9711872
Title: Identification of Alu-mediated deletions in the Fanconi anemia gene FAA.
PubMed ID: 9711872
DOI: 10.1002/(sici)1098-1004(1998)12:3<145::aid-humu2>3.0.co;2-g
PubMed ID: 9742112
Title: Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization.
PubMed ID: 9742112
PubMed ID: 12724401
Title: A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome.
PubMed ID: 12724401
PubMed ID: 9789045
Title: The Fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
PubMed ID: 9789045
PubMed ID: 15299030
Title: The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).
PubMed ID: 15299030
PubMed ID: 15502827
Title: X-linked inheritance of Fanconi anemia complementation group B.
PubMed ID: 15502827
DOI: 10.1038/ng1458
PubMed ID: 16116422
Title: A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.
PubMed ID: 16116422
DOI: 10.1038/ng1626
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18550849
Title: HES1 is a novel interactor of the Fanconi anemia core complex.
PubMed ID: 18550849
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 22343915
Title: FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway.
PubMed ID: 22343915
PubMed ID: 22705371
Title: A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.
PubMed ID: 22705371
PubMed ID: 22266823
Title: Regulation of Rev1 by the Fanconi anemia core complex.
PubMed ID: 22266823
DOI: 10.1038/nsmb.2222
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 9399890
Title: Mutations of the Fanconi anemia group A gene (FAA) in Italian patients.
PubMed ID: 9399890
DOI: 10.1086/301632
PubMed ID: 9371798
Title: Sequence variation in the Fanconi anemia gene FAA.
PubMed ID: 9371798
PubMed ID: 10521298
Title: High frequency of large intragenic deletions in the Fanconi anemia group A gene.
PubMed ID: 10521298
DOI: 10.1086/302627
PubMed ID: 10094191
Title: Heterogeneous spectrum of mutations in the Fanconi anaemia group A gene.
PubMed ID: 10094191
PubMed ID: 10210316
Title: A patient-derived mutant form of the Fanconi anemia protein, FANCA, is defective in nuclear accumulation.
PubMed ID: 10210316
PubMed ID: 9929978
Title: Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients.
PubMed ID: 9929978
PubMed ID: 11091222
Title: Fanconi anaemia group A (FANCA) mutations in Israeli non-Ashkenazi Jewish patients.
PubMed ID: 11091222
PubMed ID: 10807541
Title: Novel mutations of the FANCG gene causing alternative splicing in Japanese Fanconi anemia.
PubMed ID: 10807541
PubMed ID: 17924555
Title: Genetic subtyping of Fanconi anemia by comprehensive mutation screening.
PubMed ID: 17924555
DOI: 10.1002/humu.20625
PubMed ID: 18987736
Title: DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
PubMed ID: 18987736
DOI: 10.1038/nature07485
Sequence Information:
- Length: 1455
- Mass: 162775
- Checksum: 5A1918F2BEF4BC50
- Sequence:
MSDSWVPNSA SGQDPGGRRR AWAELLAGRV KREKYNPERA QKLKESAVRL LRSHQDLNAL LLEVEGPLCK KLSLSKVIDC DSSEAYANHS SSFIGSALQD QASRLGVPVG ILSAGMVASS VGQICTAPAE TSHPVLLTVE QRKKLSSLLE FAQYLLAHSM FSRLSFCQEL WKIQSSLLLE AVWHLHVQGI VSLQELLESH PDMHAVGSWL FRNLCCLCEQ MEASCQHADV ARAMLSDFVQ MFVLRGFQKN SDLRRTVEPE KMPQVTVDVL QRMLIFALDA LAAGVQEESS THKIVRCWFG VFSGHTLGSV ISTDPLKRFF SHTLTQILTH SPVLKASDAV QMQREWSFAR THPLLTSLYR RLFVMLSAEE LVGHLQEVLE TQEVHWQRVL SFVSALVVCF PEAQQLLEDW VARLMAQAFE SCQLDSMVTA FLVVRQAALE GPSAFLSYAD WFKASFGSTR GYHGCSKKAL VFLFTFLSEL VPFESPRYLQ VHILHPPLVP GKYRSLLTDY ISLAKTRLAD LKVSIENMGL YEDLSSAGDI TEPHSQALQD VEKAIMVFEH TGNIPVTVME ASIFRRPYYV SHFLPALLTP RVLPKVPDSR VAFIESLKRA DKIPPSLYST YCQACSAAEE KPEDAALGVR AEPNSAEEPL GQLTAALGEL RASMTDPSQR DVISAQVAVI SERLRAVLGH NEDDSSVEIS KIQLSINTPR LEPREHMAVD LLLTSFCQNL MAASSVAPPE RQGPWAALFV RTMCGRVLPA VLTRLCQLLR HQGPSLSAPH VLGLAALAVH LGESRSALPE VDVGPPAPGA GLPVPALFDS LLTCRTRDSL FFCLKFCTAA ISYSLCKFSS QSRDTLCSCL SPGLIKKFQF LMFRLFSEAR QPLSEEDVAS LSWRPLHLPS ADWQRAALSL WTHRTFREVL KEEDVHLTYQ DWLHLELEIQ PEADALSDTE RQDFHQWAIH EHFLPESSAS GGCDGDLQAA CTILVNALMD FHQSSRSYDH SENSDLVFGG RTGNEDIISR LQEMVADLEL QQDLIVPLGH TPSQEHFLFE IFRRRLQALT SGWSVAASLQ RQRELLMYKR ILLRLPSSVL CGSSFQAEQP ITARCEQFFH LVNSEMRNFC SHGGALTQDI TAHFFRGLLN ACLRSRDPSL MVDFILAKCQ TKCPLILTSA LVWWPSLEPV LLCRWRRHCQ SPLPRELQKL QEGRQFASDF LSPEAASPAP NPDWLSAAAL HFAIQQVREE NIRKQLKKLD CEREELLVFL FFFSLMGLLS SHLTSNSTTD LPKAFHVCAA ILECLEKRKI SWLALFQLTE SDLRLGRLLL RVAPDQHTRL LPFAFYSLLS YFHEDAAIRE EAFLHVAVDM YLKLVQLFVA GDTSTVSPPA GRSLELKGQG NPVELITKAR LFLLQLIPRC PKKSFSHVAE LLADRGDCDP EVSAALQSRQ QAAPDADLSQ EPHLF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.