Details for: INTS6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 423.3495
Cell Significance Index: -65.8500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 259.0645
Cell Significance Index: -65.7100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 146.3603
Cell Significance Index: -69.1000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 138.3853
Cell Significance Index: -56.2200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 126.3061
Cell Significance Index: -64.9700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 102.9921
Cell Significance Index: -69.1100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 59.3144
Cell Significance Index: -56.6300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 55.5170
Cell Significance Index: -68.4500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 24.4470
Cell Significance Index: -65.4900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 18.2454
Cell Significance Index: -56.0400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 17.5365
Cell Significance Index: -69.2000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 16.0514
Cell Significance Index: -35.1300 - Cell Name: odontoblast (CL0000060)
Fold Change: 4.9561
Cell Significance Index: 635.3400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.5354
Cell Significance Index: 67.7000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.0105
Cell Significance Index: 403.3000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.8519
Cell Significance Index: 83.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.7251
Cell Significance Index: 342.3500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.5948
Cell Significance Index: 259.3700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.1017
Cell Significance Index: 31.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.0763
Cell Significance Index: 69.4400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.0505
Cell Significance Index: 58.9500 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.0193
Cell Significance Index: 17.1700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9962
Cell Significance Index: 27.8400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.9907
Cell Significance Index: 438.0000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.9120
Cell Significance Index: 61.3200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.8449
Cell Significance Index: 22.6400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.8180
Cell Significance Index: 88.9700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.7769
Cell Significance Index: 59.6200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.7630
Cell Significance Index: 93.8200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7602
Cell Significance Index: 525.7900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7428
Cell Significance Index: 266.4300 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.6941
Cell Significance Index: 5.8300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6870
Cell Significance Index: 123.8500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.6679
Cell Significance Index: 18.1800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6199
Cell Significance Index: 85.1300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6006
Cell Significance Index: 59.4100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5342
Cell Significance Index: 291.7300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5195
Cell Significance Index: 31.1900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4605
Cell Significance Index: 415.7700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4098
Cell Significance Index: 77.9800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3696
Cell Significance Index: 19.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.3118
Cell Significance Index: 198.0000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3041
Cell Significance Index: 21.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2848
Cell Significance Index: 13.3900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2828
Cell Significance Index: 532.4100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2805
Cell Significance Index: 19.8400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.2452
Cell Significance Index: 8.5200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2175
Cell Significance Index: 98.7100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2173
Cell Significance Index: 37.1000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2108
Cell Significance Index: 10.9800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1911
Cell Significance Index: 8.9100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.1825
Cell Significance Index: 3.8200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1801
Cell Significance Index: 6.3300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1740
Cell Significance Index: 12.9700 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.1564
Cell Significance Index: 1.0600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1419
Cell Significance Index: 218.4600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0954
Cell Significance Index: 175.8700 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0875
Cell Significance Index: 11.3100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0556
Cell Significance Index: 75.5900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0338
Cell Significance Index: 0.5800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0111
Cell Significance Index: 0.2400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0081
Cell Significance Index: -5.9500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0185
Cell Significance Index: -13.6800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0566
Cell Significance Index: -3.4800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0653
Cell Significance Index: -49.4500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0670
Cell Significance Index: -41.8100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0683
Cell Significance Index: -7.8300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0808
Cell Significance Index: -45.6000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0914
Cell Significance Index: -10.7800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1598
Cell Significance Index: -7.0700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1901
Cell Significance Index: -27.6400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2050
Cell Significance Index: -58.9800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2148
Cell Significance Index: -45.2400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2178
Cell Significance Index: -4.2500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2187
Cell Significance Index: -6.2400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2232
Cell Significance Index: -26.0100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2303
Cell Significance Index: -8.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2320
Cell Significance Index: -23.7000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3179
Cell Significance Index: -3.7900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3320
Cell Significance Index: -4.5300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.3462
Cell Significance Index: -5.1100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3594
Cell Significance Index: -18.8700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.4102
Cell Significance Index: -5.8900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.4118
Cell Significance Index: -11.8700 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.5151
Cell Significance Index: -3.9700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.5230
Cell Significance Index: -32.9600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5396
Cell Significance Index: -61.5900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5441
Cell Significance Index: -56.6500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.7408
Cell Significance Index: -13.0900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7432
Cell Significance Index: -58.8700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.7625
Cell Significance Index: -16.2400 - Cell Name: peg cell (CL4033014)
Fold Change: -0.7709
Cell Significance Index: -17.8100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.9686
Cell Significance Index: -20.7100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.9785
Cell Significance Index: -25.7300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.9997
Cell Significance Index: -50.5200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -1.0946
Cell Significance Index: -10.0800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.1042
Cell Significance Index: -67.7000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.1389
Cell Significance Index: -28.4700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.2974
Cell Significance Index: -33.3500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -1.3760
Cell Significance Index: -33.0000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2852564731
Symbol: INT6_HUMAN
Name: Integrator complex subunit 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10467397
Title: Isolation of DICE1: a gene frequently affected by LOH and downregulated in lung carcinomas.
PubMed ID: 10467397
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11939413
Title: Molecular characterization of the DICE1 (DDX26) tumor suppressor gene in lung carcinoma cells.
PubMed ID: 11939413
PubMed ID: 15254679
Title: Ectopic expression of DICE1 suppresses tumor cell growth.
PubMed ID: 15254679
PubMed ID: 16007164
Title: Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer.
PubMed ID: 16007164
PubMed ID: 16271964
Title: Absence of mutations in DICE1/DDX26 gene in human cancer cell lines with frequent 13q14 deletions.
PubMed ID: 16271964
PubMed ID: 16239144
Title: Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
PubMed ID: 16239144
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 23904267
Title: Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.
PubMed ID: 23904267
Sequence Information:
- Length: 887
- Mass: 100390
- Checksum: FCD3FD61B7767E03
- Sequence:
MPILLFLIDT SASMNQRSHL GTTYLDTAKG AVETFMKLRA RDPASRGDRY MLVTFEEPPY AIKAGWKENH ATFMNELKNL QAEGLTTLGQ SLRTAFDLLN LNRLVTGIDN YGQGRNPFFL EPAIIITITD GSKLTTTSGV QDELHLPLNS PLPGSELTKE PFRWDQRLFA LVLRLPGTMS VESEQLTGVP LDDSAITPMC EVTGGRSYSV CSPRMLNQCL ESLVQKVQSG VVINFEKAGP DPSPVEDGQP DISRPFGSQP WHSCHKLIYV RPNPKTGVPI GHWPVPESFW PDQNSPTLPP RTSHPVVKFS CTDCEPMVID KLPFDKYELE PSPLTQFILE RKSPQTCWQV YVSNSAKYSE LGHPFGYLKA STALNCVNLF VMPYNYPVLL PLLDDLFKVH KAKPTLKWRQ SFESYLKTMP PYYLGPLKKA VRMMGAPNLI ADSMEYGLSY SVISYLKKLS QQAKIESDRV IGSVGKKVVQ ETGIKVRSRS HGLSMAYRKD FQQLLQGISE DVPHRLLDLN MKEYTGFQVA LLNKDLKPQT FRNAYDIPRR NLLDHLTRMR SNLLKSTRRF LKGQDEDQVH SVPIAQMGNY QEYLKQVPSP LRELDPDQPR RLHTFGNPFK LDKKGMMIDE ADEFVAGPQN KHKRPGEPNM QGIPKRRRCM SPLLRGRQQN PVVNNHIGGK GPPAPTTQAQ PDLIKPLPLH KISETTNDSI IHDVVENHVA DQLSSDITPN AMDTEFSASS PASLLERPTN HMEALGHDHL GTNDLTVGGF LENHEEPRDK EQCAEENIPA SSLNKGKKLM HCRSHEEVNT ELKAQIMKEI RKPGRKYERI FTLLKHVQGS LQTRLIFLQN VIKEASRFKK RMLIEQLENF LDEIHRRANQ INHINSN
Genular Protein ID: 3724858919
Symbol: B3KU90_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
Sequence Information:
- Length: 709
- Mass: 80512
- Checksum: 94A92B2EC617B5F8
- Sequence:
MSVESEQLTG VPLDDSAITP MCEVTGGRSY SVCSPRMLNQ CLESLVQKVQ SGVVINFEKA GPDPSPVEDG QPDISRPFGS QPWHSCHKLI YVRPNPKTGV PIGHWPVPES FWPDQNSPTL PPRTSHPVVK FSCTDCEPMV IDKLPFDKYE LEPSPLTQFI LERKSPQTCW QVYVSNSAKY SELGHPFGYL KASTALNCVN LFVMPYNYPV LLPLLDDLFK VHKAKPTLKW RQSFESYLKT MPPYYLGPLK KAVRMMGAPN LIADSMEYGL SYSVISYLKK LSQQAKIESD RVIGSVGKKV VQETGIKVRS RSHGLSMAYR KDFQQLLQGI SEDVPHRLLD LNMKEYTGFQ VALLNKDLKP QTFRNAYDIP RRNLLDHLTR MRSNLLKSTR RFLKGQDEDQ VHSVPIAQMG NYQEYLKQVP SPLRELDPDQ PRRLHTFGNP FKLDKKGMMI DEADEFVAGP QNKHKRPGEP NMQGIPKRRR CMSPLLRGRQ QNPVVNNHIG GKGPPAPTTQ AQPDLIKPLP LHKISETTND SIIHDVVENH VADQLSSDIT PNAMDTEFSA SSPASLLERP TNHMEALGHD HLGTNDLTVG GFLENHEEPR DKEQCAEENI PASSLNKGKK LMHCRSHEEV NTELKAQIMK EIRKPGRKYE RIFTLLKHVQ GSLQTRLIFL QNVIKEASRF KKRMLIEQLE NFLDEIHRRA NQINHINSN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.