Details for: INVS

Gene ID: 27130

Symbol: INVS

Ensembl ID: ENSG00000119509

Description: inversin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 300.1056
    Cell Significance Index: -46.6800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 183.5845
    Cell Significance Index: -46.5700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 86.0539
    Cell Significance Index: -34.9600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 85.3749
    Cell Significance Index: -35.1700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 37.9413
    Cell Significance Index: -46.7800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 36.6591
    Cell Significance Index: -35.0000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.7497
    Cell Significance Index: -44.8700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.2049
    Cell Significance Index: -28.9000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.9284
    Cell Significance Index: -47.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.7592
    Cell Significance Index: 154.8300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.5437
    Cell Significance Index: 49.6500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4727
    Cell Significance Index: 496.0200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.3889
    Cell Significance Index: 64.0100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.3206
    Cell Significance Index: 59.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.2396
    Cell Significance Index: 444.4600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.0642
    Cell Significance Index: 158.4000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.9221
    Cell Significance Index: 85.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.9020
    Cell Significance Index: 72.0300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.8139
    Cell Significance Index: 650.6100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 1.6951
    Cell Significance Index: 41.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.5994
    Cell Significance Index: 39.9800
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.4566
    Cell Significance Index: 12.9300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.3839
    Cell Significance Index: 38.6800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.2082
    Cell Significance Index: 835.6100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.1951
    Cell Significance Index: 25.5500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0905
    Cell Significance Index: 207.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.0459
    Cell Significance Index: 70.3300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8693
    Cell Significance Index: 53.4300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.7276
    Cell Significance Index: 17.4500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5883
    Cell Significance Index: 58.2000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5341
    Cell Significance Index: 482.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4215
    Cell Significance Index: 793.6800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.3926
    Cell Significance Index: 11.2100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3528
    Cell Significance Index: 10.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3503
    Cell Significance Index: 539.2600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2996
    Cell Significance Index: 552.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2969
    Cell Significance Index: 48.3000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.2932
    Cell Significance Index: 4.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2784
    Cell Significance Index: 176.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2253
    Cell Significance Index: 102.2400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1570
    Cell Significance Index: 2.6900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1359
    Cell Significance Index: 14.7900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1218
    Cell Significance Index: 5.5200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1144
    Cell Significance Index: 155.5200
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.0837
    Cell Significance Index: 1.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0685
    Cell Significance Index: 12.3600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0122
    Cell Significance Index: 0.1700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0020
    Cell Significance Index: 0.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0242
    Cell Significance Index: -3.5200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0258
    Cell Significance Index: -0.5600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0274
    Cell Significance Index: -3.3800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0311
    Cell Significance Index: -16.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0400
    Cell Significance Index: -29.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0479
    Cell Significance Index: -35.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0665
    Cell Significance Index: -37.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0684
    Cell Significance Index: -51.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0773
    Cell Significance Index: -9.1200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0789
    Cell Significance Index: -34.8800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0834
    Cell Significance Index: -52.0700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0966
    Cell Significance Index: -5.8000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1010
    Cell Significance Index: -1.2600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1145
    Cell Significance Index: -7.9200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1260
    Cell Significance Index: -36.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1394
    Cell Significance Index: -14.5100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1506
    Cell Significance Index: -4.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1585
    Cell Significance Index: -21.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1629
    Cell Significance Index: -18.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1751
    Cell Significance Index: -29.9100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2177
    Cell Significance Index: -45.8600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2761
    Cell Significance Index: -17.4000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2809
    Cell Significance Index: -36.0100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3155
    Cell Significance Index: -32.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3224
    Cell Significance Index: -41.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3431
    Cell Significance Index: -39.3100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.3795
    Cell Significance Index: -4.7900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4516
    Cell Significance Index: -27.6900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4584
    Cell Significance Index: -23.8100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4636
    Cell Significance Index: -21.7900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4800
    Cell Significance Index: -22.3800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4911
    Cell Significance Index: -7.2500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4914
    Cell Significance Index: -38.9200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5070
    Cell Significance Index: -26.4100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.5329
    Cell Significance Index: -6.7100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5487
    Cell Significance Index: -17.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.5627
    Cell Significance Index: -36.3000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5781
    Cell Significance Index: -11.4300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5791
    Cell Significance Index: -43.1600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5843
    Cell Significance Index: -19.1300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5974
    Cell Significance Index: -12.6800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.6032
    Cell Significance Index: -12.1100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.6336
    Cell Significance Index: -10.9600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.6473
    Cell Significance Index: -45.7800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6573
    Cell Significance Index: -11.0700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.6924
    Cell Significance Index: -10.2200
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.7098
    Cell Significance Index: -7.1600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7139
    Cell Significance Index: -37.4800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.7402
    Cell Significance Index: -10.3500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.7424
    Cell Significance Index: -5.0300
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.7999
    Cell Significance Index: -4.9400
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.8243
    Cell Significance Index: -12.5400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Ciliary Localization:** Inversin is specifically localized to the ciliary inversin compartment, a unique region within cilia that is essential for the regulation of Wnt signaling. 2. **Calmodulin Binding:** Inversin interacts with calmodulin, a calcium-binding protein, which is crucial for the regulation of its activity. 3. **Negative Regulation of Wnt Signaling:** Inversin acts as a negative regulator of the canonical Wnt signaling pathway, preventing excessive activation of this pathway. 4. **Expression in Specific Cell Types:** Inversin is expressed in various cell types, including cortical cells of the adrenal gland, lens epithelial cells, and vascular leptomeningeal cells. **Pathways and Functions:** 1. **Wnt Signaling Pathway:** Inversin's role in the negative regulation of the canonical Wnt signaling pathway is critical for maintaining cellular homeostasis and preventing aberrant cell growth. 2. **Ciliary Function:** Inversin's localization to the ciliary inversin compartment ensures proper ciliary function, which is essential for the maintenance of cellular polarity and the regulation of various signaling pathways. 3. **Cellular Polarity:** Inversin's interaction with calmodulin and its localization to the ciliary inversin compartment contribute to the establishment and maintenance of cellular polarity. **Clinical Significance:** Dysregulation of the inversin gene has been implicated in several human diseases, including: 1. **Conductive Hearing Loss:** Mutations in the INVS gene have been associated with non-syndromic hearing loss, highlighting the importance of inversin in the maintenance of auditory function. 2. **Ciliary Dyskinesia:** Inversin's role in ciliary function and the regulation of Wnt signaling pathways underscores its involvement in ciliary dyskinesia, a condition characterized by abnormal ciliary motility. 3. **Cancer:** The dysregulation of Wnt signaling pathways, in which inversin plays a critical role, has been implicated in various types of cancer, including colorectal and breast cancer. In conclusion, the inversin gene is a crucial component of the ciliary apparatus, playing a pivotal role in the regulation of Wnt signaling pathways. Its dysregulation has been implicated in several human diseases, highlighting the importance of its investigation and potential therapeutic targeting. Further research is necessary to fully elucidate the mechanisms by which inversin regulates Wnt signaling and to explore its potential as a therapeutic target for various diseases.

Genular Protein ID: 858699489

Symbol: INVS_HUMAN

Name: Inversin

UniProtKB Accession Codes:

Q9Y283 A2A2Y2 Q2NKL0 Q5W0T6 Q8IVX8 Q9BRB9 Q9Y488 Q9Y498

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 39 Ensembl 3 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11935322

Title: Identification, genomic organization, chromosomal mapping and mutation analysis of the human INV gene, the ortholog of a murine gene implicated in left-right axis development and biliary atresia.

PubMed ID: 11935322

DOI: 10.1007/s00439-001-0655-5

PubMed ID: 11941489

Title: The left-right determinant inversin has highly conserved ankyrin repeat and IQ domains and interacts with calmodulin.

PubMed ID: 11941489

DOI: 10.1007/s00439-002-0696-4

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12872123

Title: Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.

PubMed ID: 12872123

DOI: 10.1038/ng1217

PubMed ID: 15852005

Title: Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.

PubMed ID: 15852005

DOI: 10.1038/ng1552

PubMed ID: 18371931

Title: Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia.

PubMed ID: 18371931

DOI: 10.1016/j.ajhg.2008.02.017

PubMed ID: 21565611

Title: Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

PubMed ID: 21565611

DOI: 10.1016/j.cell.2011.04.019

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23793029

Title: ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.

PubMed ID: 23793029

DOI: 10.1038/ng.2681

Sequence Information:

  • Length: 1065
  • Mass: 117826
  • Checksum: DACDF33C1B8573AC
  • Sequence:
    • MNKSENLLFA GSSLASQVHA AAVNGDKGAL QRLIVGNSAL KDKEDQFGRT PLMYCVLADR 
LDCADALLKA GADVNKTDHS QRTALHLAAQ KGNYRFMKLL LTRRANWMQK DLEEMTPLHL 
TTRHRSPKCL ALLLKFMAPG EVDTQDKNKQ TALHWSAYYN NPEHVKLLIK HDSNIGIPDV 
EGKIPLHWAA NHKDPSAVHT VRCILDAAPT ESLLNWQDYE GRTPLHFAVA DGNVTVVDVL 
TSYESCNITS YDNLFRTPLH WAALLGHAQI VHLLLERNKS GTIPSDSQGA TPLHYAAQSN 
FAETVKVFLK HPSVKDDSDL EGRTSFMWAA GKGSDDVLRT MLSLKSDIDI NMADKYGGTA 
LHAAALSGHV STVKLLLENN AQVDATDVMK HTPLFRACEM GHKDVIQTLI KGGARVDLVD 
QDGHSLLHWA ALGGNADVCQ ILIENKINPN VQDYAGRTPL QCAAYGGYIN CMAVLMENNA 
DPNIQDKEGR TALHWSCNNG YLDAIKLLLD FAAFPNQMEN NEERYTPLDY ALLGERHEVI 
QFMLEHGALS IAAIQDIAAF KIQAVYKGYK VRKAFRDRKN LLMKHEQLRK DAAAKKREEE 
NKRKEAEQQK GRRSPDSCRP QALPCLPSTQ DVPSRQSRAP SKQPPAGNVA QGPEPRDSRG 
SPGGSLGGAL QKEQHVSSDL QGTNSRRPNE TAREHSKGQS ACVHFRPNEG SDGSRHPGVP 
SVEKSRGETA GDERCAKGKG FVKQPSCIRV AGPDEKGEDS RRAAASLPPH DSHWKPSRRH 
DTEPKAKCAP QKRRTQELRG GRCSPAGSSR PGSARGEAVH AGQNPPHHRT PRNKVTQAKL 
TGGLYSHLPQ STEELRSGAR RLETSTLSED FQVSKETDPA PGPLSGQSVN IDLLPVELRL 
QIIQRERRRK ELFRKKNKAA AVIQRAWRSY QLRKHLSHLR HMKQLGAGDV DRWRQESTAL 
LLQVWRKELE LKFPQTTAVS KAPKSPSKGT SGTKSTKHSV LKQIYGCSHE GKIHHPTRSV 
KASSVLRLNS VSNLQCIHLL ENSGRSKNFS YNLQSATQPK NKTKP

Genular Protein ID: 1633449597

Symbol: Q2M1I4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2M1I4

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 725
  • Mass: 80010
  • Checksum: 957245E46A9616D4
  • Sequence:
    • MNKSENLLFA GSSLASQVHA AAVNGDKGAL QRLIVGNSAL KDKEDQFGRT PLMYCVLADR 
LDCADALLKA GADVNKTDHS QRTALHLAAQ KGNYRFMKLL LTRRANWMQK DLEEMTPLHL 
TTRHRSPKCL ALLLKFMAPG EVDTQDKNKQ TALHWSAYYN NPEHVKLLIK HDSNIGIPDV 
EGKIPLHWAA NHKDPSAVHT VRCILDAAPT ESLLNWQDYE GRTPLHFAVA DGNVTVVDVL 
TSYESCNITS YDNLFRTPLH WAALLGHAQI VHLLLERNKS GTIPSDSQGA TPLHYAAQSN 
FAETVKVFLK HPSVKDDSDL EGRTSFMWAA GKGSDDVLRT MLSLKSDIDI NMADKYGGTA 
LHAAALSGHV STVKLLLENN AQVDATDVMK HTPLFRACEM GHKDVIQTLI KGGARVDLVD 
QDGHSLLHWA ALGGNADVCQ ILIENKINPN VQDYAGRTPL QCAAYGGYIN CMAVLMENNA 
DPNIQDKEGR TALHWSCNNG YLDAIKLLLD FAAFPNQMEN NEERYTPLDY ALLGERHEVI 
QFMLEHGALS IAAIQDIAAF KIQAVYKGYK VRKAFRDRKN LLMKHEQLRK DAAAKKREEE 
NKRKEAEQQK GRRSPDSCRP QALPCLPSTQ DVPSRQSRAP SKQPPAGNVA QGPEPRDSRG 
SPGGSLGGAL QKEQHVSSDL QGTNSRRPND PMKAVMEAGI QEFPLLRSPE VRQLAMSGVQ 
RGKAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.