Details for: ZNF544

Gene ID: 27300

Gene Type:  Protein-coding  - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.

Symbol: ZNF544

Ensembl ID: ENSG00000198131

Description: zinc finger protein 544

Cell Significance Landscape

Associated with

  • Gene expression (transcription)
    (R-HSA-74160)
  • Generic transcription pathway
    (R-HSA-212436)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Metal ion binding
    (GO:0046872)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Significant Cells

Cell Significance Index (CSI) scores for the chosen context(s)

  • choroid plexus epithelial cell CL0000706
    CSI 9.54
    rCSI 15.63%
    PRS 86.22
  • adipocyte CL0000136
    CSI 8.64
    rCSI 11.09%
    PRS 85.15
  • neural crest cell CL0011012
    CSI 7.76
    rCSI 6.13%
    PRS 86.24
  • cardiac muscle cell CL0000746
    CSI 6.92
    rCSI 9.92%
    PRS 85.14
  • squamous epithelial cell CL0000076
    CSI 6.67
    rCSI 15.84%
    PRS 89.22
  • alveolar adventitial fibroblast CL4028006
    CSI 6.31
    rCSI 9.96%
    PRS 93.15
  • renal interstitial pericyte CL1001318
    CSI 5.97
    rCSI 16.46%
    PRS 90.23
  • ON-bipolar cell CL0000749
    CSI 5.21
    rCSI 7.74%
    PRS 90.85
  • naive B cell CL0000788
    CSI 4.8
    rCSI 4.12%
    PRS 95.1
  • ciliated columnar cell of tracheobronchial tree CL0002145
    CSI 4.03
    rCSI 9.2%
    PRS 85.85
  • stem cell CL0000034
    CSI 3.91
    rCSI 3.77%
    PRS 88.65
  • kidney interstitial alternatively activated macrophage CL1000695
    CSI 3.72
    rCSI 9.68%
    PRS 93.91
  • plasmacytoid dendritic cell, human CL0001058
    CSI 3.48
    rCSI 2.43%
    PRS 94.94
  • ionocyte CL0005006
    CSI 3.17
    rCSI 3.39%
    PRS 93.28
  • interneuron CL0000099
    CSI 3.15
    rCSI 6.33%
    PRS 87.05
  • erythrocyte CL0000232
    CSI 3.09
    rCSI 7.01%
    PRS 90.15
  • retinal rod cell CL0000604
    CSI 3.03
    rCSI 5.34%
    PRS 88.58
  • pro-B cell CL0000826
    CSI 2.87
    rCSI 2.38%
    PRS 93.16
  • erythroblast CL0000765
    CSI 2.82
    rCSI 7.48%
    PRS 92.64
  • rod bipolar cell CL0000751
    CSI 2.77
    rCSI 4.97%
    PRS 87.89
  • Mueller cell CL0000636
    CSI 2.76
    rCSI 6.3%
    PRS 86.63
  • group 3 innate lymphoid cell CL0001071
    CSI 2.62
    rCSI 1.97%
    PRS 94.65
  • peripheral nervous system neuron CL2000032
    CSI 2.58
    rCSI 3.52%
    PRS 86.43
  • kidney loop of Henle thin descending limb epithelial cell CL1001111
    CSI 2.5
    rCSI 3.54%
    PRS 90.7
  • megakaryocyte-erythroid progenitor cell CL0000050
    CSI 2.44
    rCSI 2.21%
    PRS 91.09
  • cardiac endothelial cell CL0010008
    CSI 2.44
    rCSI 9.86%
    PRS 92.88
  • hematopoietic stem cell CL0000037
    CSI 2.4
    rCSI 1.6%
    PRS 93.4
  • retinal pigment epithelial cell CL0002586
    CSI 2.34
    rCSI 4.64%
    PRS 89.28
  • cerebral cortex GABAergic interneuron CL0010011
    CSI 2.33
    rCSI 6.87%
    PRS 91.79
  • parietal epithelial cell CL1000452
    CSI 2.24
    rCSI 5.99%
    PRS 87.91
  • pvalb GABAergic cortical interneuron CL4023018
    CSI 2.2
    rCSI 2.74%
    PRS 78.79
  • ciliated epithelial cell CL0000067
    CSI 2.18
    rCSI 1.92%
    PRS 84.36
  • retinal bipolar neuron CL0000748
    CSI 2.07
    rCSI 3.87%
    PRS 84.93
  • VIP GABAergic cortical interneuron CL4023016
    CSI 2.02
    rCSI 2.41%
    PRS 81.02
  • cerebral cortex endothelial cell CL1001602
    CSI 1.99
    rCSI 3.45%
    PRS 87.63
  • kidney connecting tubule epithelial cell CL1000768
    CSI 1.96
    rCSI 4.98%
    PRS 87.23
  • mesothelial cell CL0000077
    CSI 1.94
    rCSI 7.59%
    PRS 78.03
  • glycinergic amacrine cell CL4030028
    CSI 1.93
    rCSI 5.02%
    PRS 86.92
  • sst GABAergic cortical interneuron CL4023017
    CSI 1.91
    rCSI 2.46%
    PRS 82.07
  • ependymal cell CL0000065
    CSI 1.88
    rCSI 3.82%
    PRS 76.28
  • caudal ganglionic eminence derived cortical interneuron CL4023064
    CSI 1.88
    rCSI 3.31%
    PRS 80.41
  • retina horizontal cell CL0000745
    CSI 1.85
    rCSI 2.82%
    PRS 89.31
  • epithelial cell of proximal tubule CL0002306
    CSI 1.81
    rCSI 4.42%
    PRS 86.64
  • Schwann cell CL0002573
    CSI 1.73
    rCSI 4.91%
    PRS 89.21
  • lung ciliated cell CL1000271
    CSI 1.72
    rCSI 1.99%
    PRS 87.38
  • astrocyte of the cerebral cortex CL0002605
    CSI 1.67
    rCSI 3.74%
    PRS 81.21
  • glial cell CL0000125
    CSI 1.64
    rCSI 6.23%
    PRS 86.62
  • glutamatergic neuron CL0000679
    CSI 1.61
    rCSI 3.31%
    PRS 81.77
  • sncg GABAergic cortical interneuron CL4023015
    CSI 1.58
    rCSI 2.55%
    PRS 82.06
  • kidney loop of Henle thin ascending limb epithelial cell CL1001107
    CSI 1.57
    rCSI 4.07%
    PRS 90.18
  • lamp5 GABAergic cortical interneuron CL4023011
    CSI 1.57
    rCSI 2.63%
    PRS 81.05
  • club cell CL0000158
    CSI 1.52
    rCSI 2.22%
    PRS 88.45
  • L4 intratelencephalic projecting glutamatergic neuron CL4030063
    CSI 1.49
    rCSI 3.57%
    PRS 83.23
  • retinal cone cell CL0000573
    CSI 1.49
    rCSI 2.39%
    PRS 85.27
  • GABAergic amacrine cell CL4030027
    CSI 1.42
    rCSI 4.85%
    PRS 80.92
  • lymphoid lineage restricted progenitor cell CL0000838
    CSI 1.41
    rCSI 5.47%
    PRS 98.49
  • inhibitory interneuron CL0000498
    CSI 1.32
    rCSI 3.04%
    PRS 84.4
  • indirect pathway medium spiny neuron CL4023029
    CSI 1.24
    rCSI 29.99%
    PRS 78.97
  • direct pathway medium spiny neuron CL4023026
    CSI 1.23
    rCSI 29.55%
    PRS 78.8
  • podocyte CL0000653
    CSI 1.13
    rCSI 5.04%
    PRS 92.54
  • amacrine cell CL0000561
    CSI 1.13
    rCSI 3.26%
    PRS 84.82
  • S cone cell CL0003050
    CSI 1.08
    rCSI 4.76%
    PRS 88.58
  • H1 horizontal cell CL0004217
    CSI 1.06
    rCSI 4.19%
    PRS 86.82
  • retinal ganglion cell CL0000740
    CSI 1.04
    rCSI 2.3%
    PRS 83.13
  • regular atrial cardiac myocyte CL0002129
    CSI 1.01
    rCSI 3.24%
    PRS 89
  • H2 horizontal cell CL0004218
    CSI 0.93
    rCSI 4.62%
    PRS 87.51
  • GABAergic neuron CL0000617
    CSI 0.92
    rCSI 3.07%
    PRS 80.36
  • L2/3-6 intratelencephalic projecting glutamatergic neuron CL4023040
    CSI 0.89
    rCSI 2.16%
    PRS 78.86
  • ON midget ganglion cell CL4033046
    CSI 0.86
    rCSI 17.6%
    PRS 84.7
  • ON parasol ganglion cell CL4033052
    CSI 0.86
    rCSI 12.19%
    PRS 85.73
  • chandelier pvalb GABAergic cortical interneuron CL4023036
    CSI 0.76
    rCSI 2.39%
    PRS 83.93
  • L6b glutamatergic cortical neuron CL4023038
    CSI 0.66
    rCSI 2.07%
    PRS 82.23
  • diffuse bipolar 3a cell CL4033029
    CSI 0.63
    rCSI 4.3%
    PRS 84.91
  • OFF midget ganglion cell CL4033047
    CSI 0.61
    rCSI 12.44%
    PRS 85.34
  • near-projecting glutamatergic cortical neuron CL4023012
    CSI 0.59
    rCSI 2.23%
    PRS 81.22
  • L5 extratelencephalic projecting glutamatergic cortical neuron CL4023041
    CSI 0.59
    rCSI 2.12%
    PRS 79.13
  • corticothalamic-projecting glutamatergic cortical neuron CL4023013
    CSI 0.37
    rCSI 2.21%
    PRS 81.39

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration

Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.

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Comma-separated if multiple.
Legend:
  • Query Gene
  • Node Color (Target Cell CSI, relative to current network):
    • Very High
    • High
    • Medium
    • Low
    • Very Low
    • CSI N/A
  • Node Size: Proportional to Target Cell CSI magnitude
  • STRING PPI Edge
  • Shared Pathway Edge (ONTOLOGY)

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Other Information

This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.

## Summary [ZNF544](/details-gene/27300) is a protein-coding gene located on chromosome 19 that encodes Zinc Finger Protein 544. Functional annotations strongly suggest that [ZNF544](/details-gene/27300) acts as a DNA-binding transcription activator that positively regulates gene expression by RNA polymerase II. Consistent with its role as a transcription factor, the protein is localized to the [nucleus](/details-cell/GO:0005634). **Overall**, expression data indicate that [ZNF544](/details-gene/27300) is a significant gene in a diverse range of specialized cell types, including [choroid plexus epithelial cell](/details-cell/CL0000706), [adipocyte](/details-cell/CL0000136), and [neural crest cell](/details-cell/CL0011012), suggesting a role in maintaining unique cellular identities and functions across different tissues. ## Cellular Roles and Expression Landscape The expression profile of [ZNF544](/details-gene/27300) indicates a broad but specific functional footprint across multiple lineages. The gene's highest significance is observed in [choroid plexus epithelial cell](/details-cell/CL0000706) (CSI: 9.54), which forms the blood-cerebrospinal fluid barrier, suggesting a potential role in regulating the specialized secretory and barrier functions of this tissue. High significance is also noted in cell types associated with metabolic and structural functions, including [adipocyte](/details-cell/CL0000136) (CSI: 8.64) and [cardiac muscle cell](/details-cell/CL0000746) (CSI: 6.92), implying a possible involvement in metabolic regulation or cellular maintenance in these high-energy-demand cells. Furthermore, its prominence in developmental cell types such as [neural crest cell](/details-cell/CL0011012) (CSI: 7.76) and [stem cell](/details-cell/CL0000034) (CSI: 3.91) suggests it may play a role in lineage specification or differentiation. The diverse array of cell types where [ZNF544](/details-gene/27300) is significant, including epithelial ([squamous epithelial cell](/details-cell/CL0000076)), mesenchymal ([alveolar adventitial fibroblast](/details-cell/CL4028006)), and immune cells ([naive B cell](/details-cell/CL0000788)), highlights its likely role as a fundamental transcriptional regulator essential for establishing and maintaining a variety of specialized cellular programs. ## Pathways and Molecular Function [ZNF544](/details-gene/27300) is functionally annotated as a nuclear transcription factor. Its molecular functions are centered on DNA binding and transcriptional activation, specifically through [Dna-binding transcription activator activity, rna polymerase ii-specific](/details-cell/GO:0001228) and [Rna polymerase ii cis-regulatory region sequence-specific dna binding](/details-cell/GO:0000978). This is consistent with its classification as a zinc finger protein, which requires [Metal ion binding](/details-cell/GO:0046872) for structural integrity and function. The biological processes it participates in include the [Positive regulation of transcription by rna polymerase ii](/details-cell/GO:0045944). These activities are fundamental components of the overarching Reactome pathways [Gene expression (transcription)](https://reactome.org/content/detail/R-HSA-74160) and [Rna polymerase ii transcription](https://reactome.org/content/detail/R-HSA-73857). Additionally, proteomic studies have identified [ZNF544](/details-gene/27300) as a target for SUMOylation, a post-translational modification that can regulate transcription factor activity and protein-protein interactions ([Link](https://pubmed.ncbi.nlm.nih.gov/25218447), [Link](https://pubmed.ncbi.nlm.nih.gov/28112733)). This suggests its regulatory function may be dynamically controlled by cellular signaling pathways. ## Research Directions The diverse expression pattern of [ZNF544](/details-gene/27300) across functionally distinct cell types opens several avenues for future investigation. Its role appears to be context-specific, likely regulating unique gene programs essential for the identity of each cell type. ### Proposed Hypotheses: 1. **Hypothesis 1:** Given its top significance score in [choroid plexus epithelial cell](/details-cell/CL0000706), [ZNF544](/details-gene/27300) is a master regulator of the transcriptional program that establishes and maintains the blood-cerebrospinal fluid barrier, controlling the expression of key transporters, junctional proteins, and secreted factors. 2. **Hypothesis 2:** In [adipocyte](/details-cell/CL0000136) and [cardiac muscle cell](/details-cell/CL0000746), [ZNF544](/details-gene/27300) orchestrates the expression of genes involved in key metabolic pathways, such as lipid metabolism and energy homeostasis, and its dysregulation could contribute to metabolic disorders. 3. **Hypothesis 3:** The high significance of [ZNF544](/details-gene/27300) in progenitor populations like [neural crest cell](/details-cell/CL0011012) suggests it functions as a critical factor in developmental lineage commitment, where its expression level determines cell fate decisions. ### Experimental Approach: To test the first hypothesis regarding its role in the choroid plexus, an *in vitro* model using human induced pluripotent stem cell (iPSC)-derived choroid plexus epithelial cells could be employed. CRISPR-Cas9-mediated knockout of [ZNF544](/details-gene/27300) would be performed. The functional consequences would be assessed by measuring transepithelial electrical resistance (TEER) to evaluate barrier integrity. Furthermore, RNA-sequencing could identify global changes in the transcriptome, while Chromatin Immunoprecipitation sequencing (ChIP-seq) for [ZNF544](/details-gene/27300) would map its direct downstream gene targets, revealing the specific pathways it regulates to maintain choroid plexus function. ### Therapeutic Potential: As an intracellular transcription factor, [ZNF544](/details-gene/27300) presents a challenging target for traditional small-molecule inhibitors. However, its high specificity in certain cell types makes it conceptually attractive. If [ZNF544](/details-gene/27300) dysregulation is linked to diseases of the central nervous system (e.g., those involving altered CSF dynamics) or metabolic syndromes, targeting its downstream effectors might be a more viable therapeutic strategy. Further research into its specific transcriptional targets could uncover more druggable nodes within the pathways it controls.

Genular Protein ID: 3442650415

Symbol: ZN544_HUMAN

Name: Zinc finger protein 544

UniProtKB Accession Codes:

Q6NX49 A8K6J1 Q9UEX4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 3 ExpressionAtlas 1 GO 5 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 13 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 715
  • Mass: 81742
  • Checksum: D0F6F775D9741E03
  • Sequence:
    • MEARSMLVPP QASVCFEDVA MAFTQEEWEQ LDLAQRTLYR EVTLETWEHI VSLGLFLSKS 
DVISQLEQEE DLCRAEQEAP RDWKATLEEN RLNSEKDRAR EELSHHVEVY RSGPEEPPSL 
VLGKVQDQSN QLREHQENSL RFMVLTSERL FAQREHCELE LGGGYSLPST LSLLPTTLPT 
STGFPKPNSQ VKELKQNSAF INHEKNGADG KHCESHQCAR AFCQSIYLSK LGNVETGKKN 
PYEYIVSGDS LNYGSSLCFH GRTFSVKKSD DCKDYGNLFS HSVSLNEQKP VHFGKSQYEC 
DECRETCSES LCLVQTERSG PGETPFRCEE RCAAFPMASS FSDCNIIQTT EKPSVCNQCG 
KSFSCCKLIH QRTHTGEKPF ECTQCGKSFS QSYDLVIHQR THTGEKPYEC DLCGKSFTQR 
SKLITHQRIH TGEKPYQCIE CRKSFRWNSN LIVHQRIHTG EKPYECTHCG KSFSQSYELV 
THKRTHTGEK PFKCTQCGKS FSQKYDLVVH QRTHTGEKPY ECNLCGKSFS QSSKLITHQR 
IHTGEKPYQC IECGKSFRWN SNLVIHQRIH TGEKPYDCTH CGKSFSQSYQ LVAHKRTHTG 
EKPYECNECG KAFNRSTQLI RHLQIHTGEK PYKCNQCNKA FARSSYLVMH QRTHTGEKPF 
ECSQCGKAFS GSSNLLSHHR IHSGEKPYEC SDCGKSFRQQ SQLVVHRRTH TGEKP

Genular Protein ID: 896422275

Symbol: B4DL50_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DL50

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 2 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 687
  • Mass: 78596
  • Checksum: A9FA7F5DFA88CEFA
  • Sequence:
    • MEARSMLVPP QASVCFEDVA MAFTQEEWEQ LDLAQRTLYR EVTLETWEHI VSLDWKATLE 
ENRLNSEKDR AREELSHHVE VYRSGPEEPP SLVLGKVQDQ SNQLREHQEN SLRFMVLTSE 
RLFAQREHCE LELGGGYSLP STLSLLPTTL PTSTGFPKPN SQVKELKQNS AFINHEKNGA 
DGKHCESHQC ARAFCQSIYL SKLGNVETGK KNPYEYIVSG DSLNYGSSLC FHGRTFSVKK 
SDDCKDYGNL FSHSVSLNEQ KPVHFGKSQY ECDECRETCS ESLCLVQTER SGPGETPFRC 
EERCAAFPMA SSFSDCNIIQ TTEKPSVCNQ CGKSFSCCKL IHQRTHTGEK PFECTQCGKS 
FSQSYDLVIH QRTHTGEKPY ECDLCGKSFT QRSKLITHQR IHTGEKPYQC IECRKSFRWN 
SNLIVHQRIH TGEKPYECTH CGKSFSQSYE LVTHKRTHTG EKPFKCTQCG KSFSQKYDLV 
VHQRTHTGEK PYECNLCGKS FSQSSKLITH QRIHTGEKPY QCIECGKSFR WNSNLVIHQR 
IHTGEKPYDC THCGKSFSQS YQLVAHKRTH TGEKPYECNE CGKAFNRSTQ LIRHLQIHTG 
EKPYKCNQCN KAFARSSYLV MHQRTHTGEK PFECSQCGKA FSGSSNLLSH HRIHSGEKPY 
ECSDCGKSFR QRSQLVVHRR THTGEKP

Genular Protein ID: 3161348664

Symbol: B7ZAY1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZAY1

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 2 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 687
  • Mass: 78546
  • Checksum: 17220C1DFA88CEF9
  • Sequence:
    • MEARSMLVPP QASVCFEDVA MAFTQEEWEQ LDLAQRTLYR EVTLETWEHI VSLDWKATLE 
ENRLNSEKDR AREELSHHVE VYRSGPEEPP SLVLGKVQDQ SNQLREHQEN SLRFMVLTSE 
RLFAQREHCE LELGGGYSLP STLSLLPTTL PTSTGFPKPN SQVKELKQNS AFINDEKNGA 
DGKHCESHQC ARAFCQSIYL SKLGNVETGK KNPYEYIVSG DSLNYGSSLC FHGRTFSVKK 
SDDCKDYGNL FSHSVSLNEQ KPVHFGKSQY ECDECRETCS ESLCLVQTER SGPGETPFRC 
EERCAAFPMA SSFSDCNIIQ TTEKPSVCNQ CGKSFSCCKL IHQRTHTGEK PFECTQCGKS 
FSQSYDLVIH QRTHTGEKPY ECDLCGKSFT QRSKLITHQR IHTGEKPYQC IECRKSFRWN 
SNLIVHQRIH TGEKPYECTH CGKSFSQSYE LVTHKRTHTG EKPFKCTQCG KSFSQKYDLV 
VHQRTHTGEK PYECNLCGKS FSQSSKLITH QRIHTGEKPY QCIECGKSFR WNSNLVIHQR 
IHTGEKPYDC THCGKSFSQS YQLVAHKRTH TGEKPYECNE CGKAFNRSTQ LIRHLQIHTG 
EKPYKCNQCN KAFARSSYLV MHQRTHTGEK PFECSQCGKA FSGSSNLLSH HRIHSGEKPY 
ECSDCGKSFR QQSQLVVHRR THTGEKP

Genular Protein ID: 3941689483

Symbol: M0R2F0_HUMAN

Name: N/A

UniProtKB Accession Codes:

M0R2F0

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 5 GO 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 Proteomes 2 RefSeq 4 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 75
  • Mass: 8461
  • Checksum: E170508BB0990A81
  • Sequence:
    • MEARSMLVPP QASVCFEDVA MAFTQEEWEQ LDLAQRTLYR EVTLETWEHI VSLAGARRGP 
VQGRAGGPPR LESYP

Genular Protein ID: 480618009

Symbol: J3KQC8_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KQC8

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 3 GO 2 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 3 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 687
  • Mass: 78568
  • Checksum: 146A7F5DFA88CEF9
  • Sequence:
    • MEARSMLVPP QASVCFEDVA MAFTQEEWEQ LDLAQRTLYR EVTLETWEHI VSLDWKATLE 
ENRLNSEKDR AREELSHHVE VYRSGPEEPP SLVLGKVQDQ SNQLREHQEN SLRFMVLTSE 
RLFAQREHCE LELGGGYSLP STLSLLPTTL PTSTGFPKPN SQVKELKQNS AFINHEKNGA 
DGKHCESHQC ARAFCQSIYL SKLGNVETGK KNPYEYIVSG DSLNYGSSLC FHGRTFSVKK 
SDDCKDYGNL FSHSVSLNEQ KPVHFGKSQY ECDECRETCS ESLCLVQTER SGPGETPFRC 
EERCAAFPMA SSFSDCNIIQ TTEKPSVCNQ CGKSFSCCKL IHQRTHTGEK PFECTQCGKS 
FSQSYDLVIH QRTHTGEKPY ECDLCGKSFT QRSKLITHQR IHTGEKPYQC IECRKSFRWN 
SNLIVHQRIH TGEKPYECTH CGKSFSQSYE LVTHKRTHTG EKPFKCTQCG KSFSQKYDLV 
VHQRTHTGEK PYECNLCGKS FSQSSKLITH QRIHTGEKPY QCIECGKSFR WNSNLVIHQR 
IHTGEKPYDC THCGKSFSQS YQLVAHKRTH TGEKPYECNE CGKAFNRSTQ LIRHLQIHTG 
EKPYKCNQCN KAFARSSYLV MHQRTHTGEK PFECSQCGKA FSGSSNLLSH HRIHSGEKPY 
ECSDCGKSFR QQSQLVVHRR THTGEKP

Genular Protein ID: 1648412830

Symbol: M0QZM7_HUMAN

Name: N/A

UniProtKB Accession Codes:

M0QZM7

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 97
  • Mass: 11414
  • Checksum: 947A4F85D8F3102F
  • Sequence:
    • MEARSMLVPP QASVCFEDVA MAFTQEEWEQ LDLAQRTLYR EVTLETWEHI VSLGLFLSKS 
DVISQLEQEE DLCRAEQEAP RGTRPSKKQR RYRARRI