Details for: GMDS
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 376.6107
Cell Significance Index: -58.5800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 220.5459
Cell Significance Index: -55.9400 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 135.8182
Cell Significance Index: -55.9500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 123.0009
Cell Significance Index: -49.9700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 88.4621
Cell Significance Index: -59.3600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 52.5482
Cell Significance Index: -50.1700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 47.9498
Cell Significance Index: -59.1200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 20.2288
Cell Significance Index: -54.1900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 18.9483
Cell Significance Index: -41.4700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.8478
Cell Significance Index: -58.5900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 10.1802
Cell Significance Index: 217.6100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 6.7771
Cell Significance Index: 315.9800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 6.3318
Cell Significance Index: 437.8800 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 5.3770
Cell Significance Index: 47.7300 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 5.1818
Cell Significance Index: 31.9700 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 4.4737
Cell Significance Index: 45.1300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 3.5159
Cell Significance Index: 155.5200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 3.5108
Cell Significance Index: 210.7700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 3.3321
Cell Significance Index: 126.1800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 2.7277
Cell Significance Index: 2462.8700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6094
Cell Significance Index: 523.4400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.4491
Cell Significance Index: 878.4600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.2939
Cell Significance Index: 455.2300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.1581
Cell Significance Index: 1492.6400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.0653
Cell Significance Index: 138.8700 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 2.0226
Cell Significance Index: 20.2400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.9519
Cell Significance Index: 55.7000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.6177
Cell Significance Index: 45.2100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.3802
Cell Significance Index: 162.7700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.2194
Cell Significance Index: 26.7000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.1540
Cell Significance Index: 33.2500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.8411
Cell Significance Index: 39.5300 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.8399
Cell Significance Index: 12.0800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7820
Cell Significance Index: 77.3600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.7320
Cell Significance Index: 44.9900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5864
Cell Significance Index: 26.5800 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 0.5389
Cell Significance Index: 11.2400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.4561
Cell Significance Index: 289.6600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4340
Cell Significance Index: 237.0300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4156
Cell Significance Index: 23.3200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.3989
Cell Significance Index: 181.0400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3884
Cell Significance Index: 171.7000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.3641
Cell Significance Index: 11.6600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3332
Cell Significance Index: 40.9700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.3210
Cell Significance Index: 24.6300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3166
Cell Significance Index: 57.0700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2646
Cell Significance Index: 4.5400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2427
Cell Significance Index: 5.8200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2184
Cell Significance Index: 37.2900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1834
Cell Significance Index: 34.9100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1509
Cell Significance Index: 284.1300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1339
Cell Significance Index: 9.4700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1004
Cell Significance Index: 185.0900 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0839
Cell Significance Index: 10.8400 - Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: 0.0647
Cell Significance Index: 0.3600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0446
Cell Significance Index: 68.7000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0037
Cell Significance Index: -0.1000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0213
Cell Significance Index: -15.6200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0230
Cell Significance Index: -31.2300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0491
Cell Significance Index: -2.5500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0624
Cell Significance Index: -46.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0636
Cell Significance Index: -48.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1035
Cell Significance Index: -58.3800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1071
Cell Significance Index: -66.8600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1509
Cell Significance Index: -2.9500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1566
Cell Significance Index: -18.2600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1640
Cell Significance Index: -23.8400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1780
Cell Significance Index: -51.2300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1892
Cell Significance Index: -19.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.2179
Cell Significance Index: -29.9200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2342
Cell Significance Index: -30.0200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2426
Cell Significance Index: -3.3100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2665
Cell Significance Index: -27.2200 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.2909
Cell Significance Index: -3.8800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3027
Cell Significance Index: -63.7500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3798
Cell Significance Index: -24.5100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.3817
Cell Significance Index: -6.4300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3865
Cell Significance Index: -13.4300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3906
Cell Significance Index: -29.1100 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.4351
Cell Significance Index: -6.6200 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4403
Cell Significance Index: -4.0600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4506
Cell Significance Index: -51.6300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.4552
Cell Significance Index: -6.8200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5750
Cell Significance Index: -45.5400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.6309
Cell Significance Index: -32.8700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.6673
Cell Significance Index: -9.8500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6784
Cell Significance Index: -22.2100 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.6936
Cell Significance Index: -14.7200 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.6982
Cell Significance Index: -8.6600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.7027
Cell Significance Index: -22.3800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.7143
Cell Significance Index: -18.3600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7668
Cell Significance Index: -47.0100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.8589
Cell Significance Index: -12.3000 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -0.8643
Cell Significance Index: -5.3700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.9009
Cell Significance Index: -22.5200 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.9043
Cell Significance Index: -17.8800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.9618
Cell Significance Index: -19.3100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.0138
Cell Significance Index: -63.9000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.0142
Cell Significance Index: -25.9100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.0224
Cell Significance Index: -53.6800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2968091807
Symbol: GMDS_HUMAN
Name: GDP-D-mannose dehydratase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9525924
Title: Molecular cloning of human GDP-mannose 4,6-dehydratase and reconstitution of GDP-fucose biosynthesis in vitro.
PubMed ID: 9525924
PubMed ID: 9603974
Title: Molecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cells.
PubMed ID: 9603974
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 372
- Mass: 41950
- Checksum: B1BAC441736D4C2B
- Sequence:
MAHAPARCPS ARGSGDGEMG KPRNVALITG ITGQDGSYLA EFLLEKGYEV HGIVRRSSSF NTGRIEHLYK NPQAHIEGNM KLHYGDLTDS TCLVKIINEV KPTEIYNLGA QSHVKISFDL AEYTADVDGV GTLRLLDAVK TCGLINSVKF YQASTSELYG KVQEIPQKET TPFYPRSPYG AAKLYAYWIV VNFREAYNLF AVNGILFNHE SPRRGANFVT RKISRSVAKI YLGQLECFSL GNLDAKRDWG HAKDYVEAMW LMLQNDEPED FVIATGEVHS VREFVEKSFL HIGKTIVWEG KNENEVGRCK ETGKVHVTVD LKYYRPTEVD FLQGDCTKAK QKLNWKPRVA FDELVREMVH ADVELMRTNP NA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.