Details for: GPD2
Gene ID: 2820
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: GPD2
Ensembl ID: ENSG00000115159
Description: glycerol-3-phosphate dehydrogenase 2
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 17.15rCSI 42.46%PRS 41.88
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CSI 14.29rCSI 10.59%PRS 37.73
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CSI 13.5rCSI 42.21%PRS 29.96
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CSI 9.91rCSI 12.78%PRS 29.7
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CSI 7.6rCSI 12.51%PRS 49.32
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CSI 7.26rCSI 12.81%PRS 27.84
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CSI 6.76rCSI 10.78%PRS 37.96
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CSI 6.57rCSI 7.58%PRS 38.42
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CSI 6.27rCSI 14.3%PRS 42.53
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CSI 6.01rCSI 8.52%PRS 40.89
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CSI 5.96rCSI 8.15%PRS 46.43
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CSI 5.86rCSI 32.77%PRS 56.72
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CSI 5.78rCSI 12.8%PRS 41.21
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CSI 5.5rCSI 12.33%PRS 29.48
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CSI 5.21rCSI 8.54%PRS 34.94
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CSI 4.77rCSI 6.38%PRS 52.19
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CSI 4.66rCSI 7.5%PRS 30.84
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CSI 4.41rCSI 7.62%PRS 34.93
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CSI 4.36rCSI 5.27%PRS 51.45
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CSI 4.27rCSI 7.99%PRS 34.06
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CSI 4.21rCSI 9.63%PRS 43.21
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CSI 4.12rCSI 8.28%PRS 34.16
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CSI 3.96rCSI 3.9%PRS 46.09
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CSI 3.9rCSI 8.58%PRS 47.79
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CSI 3.87rCSI 11.49%PRS 55.62
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CSI 3.69rCSI 4.73%PRS 48.55
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CSI 3.53rCSI 8.06%PRS 37.58
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CSI 3.51rCSI 9.25%PRS 66.43
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CSI 3.49rCSI 5.55%PRS 37.27
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CSI 3.32rCSI 4.87%PRS 40
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CSI 3.25rCSI 3.07%PRS 44.84
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CSI 3.19rCSI 2.52%PRS 32.13
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CSI 3.16rCSI 3.93%PRS 27.36
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CSI 3.13rCSI 3.28%PRS 46.5
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CSI 3.1rCSI 7.85%PRS 52.01
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CSI 2.95rCSI 15.12%PRS 47.47
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CSI 2.93rCSI 12.46%PRS 41.34
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CSI 2.93rCSI 3.5%PRS 28.79
-
CSI 2.87rCSI 3.68%PRS 39.62
-
CSI 2.84rCSI 8.22%PRS 35.64
-
CSI 2.67rCSI 2.79%PRS 44.56
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CSI 2.66rCSI 5.94%PRS 50.3
-
CSI 2.63rCSI 2.62%PRS 38.29
-
CSI 2.61rCSI 5.74%PRS 58.27
-
CSI 2.6rCSI 3.24%PRS 46.52
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CSI 2.6rCSI 9.74%PRS 37.18
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CSI 2.56rCSI 2.38%PRS 43.65
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CSI 2.54rCSI 5.27%PRS 41.78
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CSI 2.53rCSI 8.4%PRS 45.78
-
CSI 2.49rCSI 5.58%PRS 63.76
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CSI 2.46rCSI 11.81%PRS 42.25
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CSI 2.43rCSI 4.26%PRS 36.43
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CSI 2.41rCSI 3.22%PRS 45.37
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CSI 2.41rCSI 3.57%PRS 48.77
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CSI 2.33rCSI 3.56%PRS 52.84
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CSI 2.3rCSI 2.52%PRS 47.61
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CSI 2.29rCSI 13.19%PRS 45.94
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CSI 2.28rCSI 1.77%PRS 44.25
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CSI 2.27rCSI 4.08%PRS 37.52
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CSI 2.23rCSI 10.67%PRS 45.51
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CSI 2.21rCSI 2.03%PRS 51.1
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CSI 2.18rCSI 52.23%PRS 28.29
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CSI 2.17rCSI 6.18%PRS 43.89
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CSI 2.16rCSI 4.99%PRS 36
-
CSI 2.16rCSI 3.41%PRS 44.79
-
CSI 2.13rCSI 5.7%PRS 37.07
-
CSI 2.11rCSI 2.26%PRS 41.82
-
CSI 2.11rCSI 6.74%PRS 40.83
-
CSI 2.07rCSI 1.91%PRS 44.83
-
CSI 2.06rCSI 3.1%PRS 45.81
-
CSI 2.05rCSI 1.72%PRS 48.85
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CSI 2.03rCSI 3.69%PRS 37.58
-
CSI 2.02rCSI 2.9%PRS 35.56
-
CSI 2.02rCSI 48.66%PRS 29.18
-
CSI 2.01rCSI 2.08%PRS 49.59
-
CSI 1.96rCSI 6.56%PRS 32.78
-
CSI 1.95rCSI 2.86%PRS 46.78
-
CSI 1.89rCSI 4.94%PRS 42.93
-
CSI 1.89rCSI 7.4%PRS 21.76
-
CSI 1.88rCSI 3.16%PRS 28.81
-
CSI 1.84rCSI 3.47%PRS 54.01
-
CSI 1.78rCSI 4.63%PRS 43.65
-
CSI 1.78rCSI 2.71%PRS 44.47
-
CSI 1.77rCSI 2.42%PRS 40.38
-
CSI 1.76rCSI 2.2%PRS 55.21
-
CSI 1.74rCSI 2.78%PRS 47.53
-
CSI 1.69rCSI 2.24%PRS 48.5
-
CSI 1.68rCSI 1.76%PRS 41.19
-
CSI 1.65rCSI 3.92%PRS 46.09
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CSI 1.64rCSI 2.89%PRS 42.32
-
CSI 1.53rCSI 1.47%PRS 44.34
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CSI 1.52rCSI 3.69%PRS 28
-
CSI 1.52rCSI 2.36%PRS 53.78
-
CSI 1.5rCSI 3.81%PRS 34.8
-
CSI 1.49rCSI 6.01%PRS 42.4
-
CSI 1.45rCSI 3.83%PRS 51.26
-
CSI 1.45rCSI 3.37%PRS 61.78
-
CSI 1.43rCSI 3.68%PRS 46.76
-
CSI 1.37rCSI 6.04%PRS 37.64
-
CSI 1.37rCSI 3.55%PRS 49.05
-
CSI 0.2rCSI 1.3%PRS 31.9%
-
CSI 0.2rCSI 2.1%PRS 45.3%
-
CSI 0.3rCSI 1.8%PRS 58.6%
-
CSI 0.5rCSI 1.8%PRS 27.7%
-
CSI 0.5rCSI 3.7%PRS 42.0%
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CSI 0.6rCSI 1.1%PRS 60.1%
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CSI 0.7rCSI 4.9%PRS 39.9%
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CSI 0.7rCSI 2.4%PRS 35.9%
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CSI 0.7rCSI 4.7%PRS 43.0%
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CSI 0.8rCSI 1.9%PRS 49.6%
-
CSI 0.8rCSI 4.9%PRS 30.2%
-
CSI 0.9rCSI 3.8%PRS 41.7%
-
CSI 0.9rCSI 1.9%PRS 32.7%
-
CSI 0.9rCSI 7.0%PRS 32.3%
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CSI 1.0rCSI 1.5%PRS 54.4%
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CSI 1.0rCSI 2.7%PRS 40.7%
-
CSI 1.0rCSI 23.0%PRS 66.6%
-
CSI 1.0rCSI 2.5%PRS 54.0%
-
CSI 1.1rCSI 0.8%PRS 42.6%
-
CSI 1.1rCSI 1.8%PRS 35.0%
-
CSI 1.1rCSI 3.6%PRS 46.0%
-
CSI 1.2rCSI 7.3%PRS 36.6%
-
CSI 1.2rCSI 1.8%PRS 48.4%
-
CSI 1.2rCSI 2.5%PRS 38.6%
-
CSI 1.2rCSI 2.1%PRS 53.0%
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CSI 1.2rCSI 2.7%PRS 53.8%
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CSI 1.3rCSI 10.3%PRS 38.6%
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CSI 1.3rCSI 3.3%PRS 40.2%
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CSI 1.3rCSI 4.9%PRS 29.8%
-
CSI 1.3rCSI 4.0%PRS 32.2%
-
CSI 1.3rCSI 4.2%PRS 43.2%
-
CSI 1.3rCSI 1.9%PRS 51.2%
-
CSI 1.3rCSI 1.6%PRS 39.8%
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CSI 1.3rCSI 3.7%PRS 58.4%
-
CSI 1.3rCSI 3.3%PRS 40.1%
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CSI 1.4rCSI 1.6%PRS 34.4%
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CSI 1.4rCSI 3.6%PRS 49.1%
-
CSI 1.4rCSI 6.0%PRS 37.6%
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CSI 1.4rCSI 3.7%PRS 46.8%
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CSI 1.5rCSI 3.4%PRS 61.8%
-
CSI 1.5rCSI 3.8%PRS 51.3%
-
CSI 1.5rCSI 6.0%PRS 42.4%
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CSI 1.5rCSI 3.8%PRS 34.8%
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CSI 1.5rCSI 2.4%PRS 53.8%
-
CSI 1.5rCSI 3.7%PRS 28.0%
-
CSI 1.5rCSI 1.5%PRS 44.3%
-
CSI 1.6rCSI 2.9%PRS 42.3%
-
CSI 1.7rCSI 3.9%PRS 46.1%
-
CSI 1.7rCSI 1.8%PRS 41.2%
-
CSI 1.7rCSI 2.2%PRS 48.5%
-
CSI 1.7rCSI 2.8%PRS 47.5%
-
CSI 1.8rCSI 2.2%PRS 55.2%
-
CSI 1.8rCSI 2.4%PRS 40.4%
-
CSI 1.8rCSI 2.7%PRS 44.5%
-
CSI 1.8rCSI 4.6%PRS 43.7%
-
CSI 1.8rCSI 3.5%PRS 54.0%
-
CSI 1.9rCSI 3.2%PRS 28.8%
-
CSI 1.9rCSI 7.4%PRS 21.8%
-
CSI 1.9rCSI 4.9%PRS 42.9%
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CSI 2.0rCSI 2.9%PRS 46.8%
-
CSI 2.0rCSI 6.6%PRS 32.8%
-
CSI 2.0rCSI 2.1%PRS 49.6%
-
CSI 2.0rCSI 48.7%PRS 29.2%
-
CSI 2.0rCSI 2.9%PRS 35.6%
-
CSI 2.0rCSI 3.7%PRS 37.6%
-
CSI 2.1rCSI 1.7%PRS 48.9%
-
CSI 2.1rCSI 3.1%PRS 45.8%
-
CSI 2.1rCSI 1.9%PRS 44.8%
-
CSI 2.1rCSI 6.7%PRS 40.8%
-
CSI 2.1rCSI 2.3%PRS 41.8%
-
CSI 2.1rCSI 5.7%PRS 37.1%
-
CSI 2.2rCSI 3.4%PRS 44.8%
-
CSI 2.2rCSI 5.0%PRS 36.0%
-
CSI 2.2rCSI 6.2%PRS 43.9%
-
CSI 2.2rCSI 52.2%PRS 28.3%
-
CSI 2.2rCSI 2.0%PRS 51.1%
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CSI 2.2rCSI 10.7%PRS 45.5%
-
CSI 2.3rCSI 4.1%PRS 37.5%
-
CSI 2.3rCSI 1.8%PRS 44.3%
-
CSI 2.3rCSI 13.2%PRS 45.9%
-
CSI 2.3rCSI 2.5%PRS 47.6%
-
CSI 2.3rCSI 3.6%PRS 52.8%
-
CSI 2.4rCSI 3.6%PRS 48.8%
-
CSI 2.4rCSI 3.2%PRS 45.4%
-
CSI 2.4rCSI 4.3%PRS 36.4%
-
CSI 2.5rCSI 11.8%PRS 42.3%
-
CSI 2.5rCSI 5.6%PRS 63.8%
-
CSI 2.5rCSI 8.4%PRS 45.8%
-
CSI 2.5rCSI 5.3%PRS 41.8%
-
CSI 2.6rCSI 2.4%PRS 43.7%
-
CSI 2.6rCSI 9.7%PRS 37.2%
-
CSI 2.6rCSI 3.2%PRS 46.5%
-
CSI 2.6rCSI 5.7%PRS 58.3%
-
CSI 2.6rCSI 2.6%PRS 38.3%
-
CSI 2.7rCSI 5.9%PRS 50.3%
-
CSI 2.7rCSI 2.8%PRS 44.6%
-
CSI 2.8rCSI 8.2%PRS 35.6%
-
CSI 2.9rCSI 3.7%PRS 39.6%
-
CSI 2.9rCSI 3.5%PRS 28.8%
-
CSI 2.9rCSI 12.5%PRS 41.3%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 3626871269
Symbol: GPDM_HUMAN
Name: mtGPD
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7821823
Title: The sequence of a human mitochondrial glycerol-3-phosphate dehydrogenase-encoding cDNA.
PubMed ID: 7821823
PubMed ID: 8549872
Title: Mitochondrial glycerol-3-phosphate dehydrogenase. Cloning of an alternatively spliced human islet-cell cDNA, tissue distribution, physical mapping, and identification of a polymorphic genetic marker.
PubMed ID: 8549872
PubMed ID: 8682323
Title: Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene.
PubMed ID: 8682323
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 9110174
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 9070847
Title: Mutation in the calcium-binding domain of the mitochondrial glycerophosphate dehydrogenase gene in a family of diabetic subjects.
PubMed ID: 9070847
Sequence Information:
- Length: 727
- Mass: 80853
- Checksum: 70D8B4E5CB4F2EFD
- Sequence:
MAFQKAVKGT ILVGGGALAT VLGLSQFAHY RRKQMNLAYV KAADCISEPV NREPPSREAQ LLTLQNTSEF DILVIGGGAT GSGCALDAVT RGLKTALVER DDFSSGTSSR STKLIHGGVR YLQKAIMKLD IEQYRMVKEA LHERANLLEI APHLSAPLPI MLPVYKWWQL PYYWVGIKLY DLVAGSNCLK SSYVLSKSRA LEHFPMLQKD KLVGAIVYYD GQHNDARMNL AIALTAARYG AATANYMEVV SLLKKTDPQT GKVRVSGARC KDVLTGQEFD VRAKCVINAT GPFTDSVRKM DDKDAAAICQ PSAGVHIVMP GYYSPESMGL LDPATSDGRV IFFLPWQKMT IAGTTDTPTD VTHHPIPSEE DINFILNEVR NYLSCDVEVR RGDVLAAWSG IRPLVTDPKS ADTQSISRNH VVDISESGLI TIAGGKWTTY RSMAEDTINA AVKTHNLKAG PSRTVGLFLQ GGKDWSPTLY IRLVQDYGLE SEVAQHLAAT YGDKAFEVAK MASVTGKRWP IVGVRLVSEF PYIEAEVKYG IKEYACTAVD MISRRTRLAF LNVQAAEEAL PRIVELMGRE LNWDDYKKQE QLETARKFLY YEMGYKSRSE QLTDRSEISL LPSDIDRYKK RFHKFDADQK GFITIVDVQR VLESINVQMD ENTLHEILNE VDLNKNGQVE LNEFLQLMSA IQKGRVSGSR LAILMKTAEE NLDRRVPIPV DRSCGGL