Details for: USP25

Gene ID: 29761

Symbol: USP25

Ensembl ID: ENSG00000155313

Description: ubiquitin specific peptidase 25

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 302.0343
    Cell Significance Index: -46.9800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 186.6991
    Cell Significance Index: -47.3600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 103.8819
    Cell Significance Index: -49.0500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 99.6475
    Cell Significance Index: -40.4800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 88.0663
    Cell Significance Index: -45.3000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 42.6450
    Cell Significance Index: -40.7200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.7930
    Cell Significance Index: -47.8300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.0670
    Cell Significance Index: -45.7200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.6934
    Cell Significance Index: -45.1300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.7075
    Cell Significance Index: -30.0000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.2186
    Cell Significance Index: -48.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 4.8083
    Cell Significance Index: 128.3900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.4037
    Cell Significance Index: 150.5600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.3963
    Cell Significance Index: 87.3000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.1996
    Cell Significance Index: 121.1600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.5395
    Cell Significance Index: 72.4700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.4855
    Cell Significance Index: 48.5100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.1759
    Cell Significance Index: 46.5100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.0598
    Cell Significance Index: 158.0700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 1.9419
    Cell Significance Index: 47.3800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7999
    Cell Significance Index: 357.2000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.7930
    Cell Significance Index: 120.5600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6708
    Cell Significance Index: 165.2800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.6349
    Cell Significance Index: 91.7400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.5661
    Cell Significance Index: 561.7200
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 1.5029
    Cell Significance Index: 24.2500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4559
    Cell Significance Index: 236.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.1209
    Cell Significance Index: 28.0200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0130
    Cell Significance Index: 14.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.8752
    Cell Significance Index: 24.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8639
    Cell Significance Index: 597.4800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7852
    Cell Significance Index: 85.4100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6498
    Cell Significance Index: 39.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5994
    Cell Significance Index: 27.1700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4453
    Cell Significance Index: 12.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.3592
    Cell Significance Index: 9.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3035
    Cell Significance Index: 60.8900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2975
    Cell Significance Index: 162.4900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2781
    Cell Significance Index: 50.1400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2781
    Cell Significance Index: 19.2400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2714
    Cell Significance Index: 6.5100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2282
    Cell Significance Index: 28.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2252
    Cell Significance Index: 4.9300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2048
    Cell Significance Index: 385.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1713
    Cell Significance Index: 263.7200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1704
    Cell Significance Index: 314.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1675
    Cell Significance Index: 106.3900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.1549
    Cell Significance Index: 2.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1527
    Cell Significance Index: 69.3100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1330
    Cell Significance Index: 120.0900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1196
    Cell Significance Index: 22.7700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1053
    Cell Significance Index: 4.9500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0856
    Cell Significance Index: 116.4000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0774
    Cell Significance Index: 34.2400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0508
    Cell Significance Index: 1.1000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0418
    Cell Significance Index: 1.9500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0317
    Cell Significance Index: 4.3500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0088
    Cell Significance Index: -0.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0170
    Cell Significance Index: -12.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0328
    Cell Significance Index: -4.7700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0488
    Cell Significance Index: -0.7200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0511
    Cell Significance Index: -38.7100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0537
    Cell Significance Index: -39.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0826
    Cell Significance Index: -46.6000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0836
    Cell Significance Index: -14.2700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0871
    Cell Significance Index: -54.3700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0977
    Cell Significance Index: -5.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1256
    Cell Significance Index: -8.1000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1457
    Cell Significance Index: -41.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1700
    Cell Significance Index: -19.8100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1705
    Cell Significance Index: -1.0300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2072
    Cell Significance Index: -3.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2172
    Cell Significance Index: -22.1900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2223
    Cell Significance Index: -26.2200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2417
    Cell Significance Index: -31.2300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2561
    Cell Significance Index: -53.9400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2818
    Cell Significance Index: -36.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2923
    Cell Significance Index: -30.4400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3372
    Cell Significance Index: -38.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3552
    Cell Significance Index: -26.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3633
    Cell Significance Index: -18.8700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.3900
    Cell Significance Index: -5.6000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.4136
    Cell Significance Index: -8.5800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4287
    Cell Significance Index: -9.1300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4628
    Cell Significance Index: -23.3900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4820
    Cell Significance Index: -6.0100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4919
    Cell Significance Index: -38.9600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4962
    Cell Significance Index: -17.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5085
    Cell Significance Index: -35.9600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5125
    Cell Significance Index: -7.5700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6590
    Cell Significance Index: -40.4000
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.6611
    Cell Significance Index: -8.3300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6863
    Cell Significance Index: -21.9800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6866
    Cell Significance Index: -22.4800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.6941
    Cell Significance Index: -8.7600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7050
    Cell Significance Index: -22.4500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7194
    Cell Significance Index: -45.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.7370
    Cell Significance Index: -20.0600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.7588
    Cell Significance Index: -11.3700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7999
    Cell Significance Index: -42.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** USP25 is a cysteine-type deubiquitinating enzyme that exhibits a high degree of specificity for removing ubiquitin and ubiquitin-like proteins from lysine residues on target proteins. The enzyme is characterized by its ability to recognize and degrade various types of ubiquitin-containing proteins, including protein ubiquitination, sumoylation, and ubiquitin-like protein modifications. USP25 has been shown to be involved in negative regulation of the erad pathway, a process that is critical for maintaining cellular homeostasis and preventing disease. **Pathways and Functions:** USP25 plays a critical role in various cellular pathways, including: 1. **Protein Degradation:** USP25 is involved in the regulation of protein degradation through the removal of ubiquitin and ubiquitin-like proteins from lysine residues on target proteins. 2. **Protein Stability:** USP25 helps to maintain protein stability by removing ubiquitin and ubiquitin-like proteins that can promote protein degradation. 3. **Cell Signaling:** USP25 is involved in various cell signaling pathways, including the regulation of protein activity, localization, and stability. 4. **Metabolism:** USP25 plays a role in regulating metabolic processes, including the degradation of ubiquitin-containing proteins that are involved in energy metabolism. **Clinical Significance:** Dysregulation of USP25 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic disorders. For example: 1. **Cancer:** USP25 has been shown to be overexpressed in certain types of cancer, including breast cancer and colon cancer, where it can contribute to tumorigenesis and metastasis. 2. **Neurodegenerative Disorders:** USP25 has been implicated in the regulation of protein stability and function in neurons, and its dysregulation has been linked to neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. 3. **Metabolic Disorders:** USP25 plays a critical role in regulating metabolic processes, and its dysregulation has been linked to metabolic disorders such as diabetes and obesity. In conclusion, USP25 is a critical regulator of protein stability and function that plays a key role in maintaining cellular homeostasis and regulating various cellular processes. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of USP25 and its role in human disease.

Genular Protein ID: 1119117052

Symbol: UBP25_HUMAN

Name: Ubiquitin carboxyl-terminal hydrolase 25

UniProtKB Accession Codes:

Q9UHP3 C0LSZ0 Q6DHZ9 Q9H9W1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 Ensembl 3 ExpressionAtlas 1 GO 22 Gene3D 3 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10644437

Title: USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2.

PubMed ID: 10644437

DOI: 10.1006/geno.1999.6025

PubMed ID: 10612803

Title: Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment.

PubMed ID: 10612803

DOI: 10.1002/(sici)1098-2264(200002)27:2<153::aid-gcc6>3.3.co;2-1

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11597335

Title: Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25.

PubMed ID: 11597335

DOI: 10.1186/gb-2001-2-10-research0043

PubMed ID: 16501887

Title: The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.

PubMed ID: 16501887

DOI: 10.1007/s00018-005-5533-1

PubMed ID: 18538659

Title: Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25.

PubMed ID: 18538659

DOI: 10.1016/j.molcel.2008.03.021

PubMed ID: 19440361

Title: The UBA-UIM domains of the USP25 regulate the enzyme ubiquitination state and modulate substrate recognition.

PubMed ID: 19440361

DOI: 10.1371/journal.pone.0005571

PubMed ID: 19909739

Title: Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase.

PubMed ID: 19909739

DOI: 10.1016/j.yexcr.2009.10.023

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23042150

Title: Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25.

PubMed ID: 23042150

DOI: 10.1038/ni.2427

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 29518389

Title: Smurf1 restricts the antiviral function mediated by USP25 through promoting its ubiquitination and degradation.

PubMed ID: 29518389

DOI: 10.1016/j.bbrc.2018.03.015

PubMed ID: 30579117

Title: USP25 promotes endotoxin tolerance via suppressing K48-linked ubiquitination and degradation of TRAF3 in Kupffer cells.

PubMed ID: 30579117

DOI: 10.1016/j.molimm.2018.12.017

PubMed ID: 37339955

Title: USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice.

PubMed ID: 37339955

DOI: 10.1038/s41467-023-39412-6

PubMed ID: 37683630

Title: Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection.

PubMed ID: 37683630

DOI: 10.1016/j.devcel.2023.08.013

PubMed ID: 28619731

Title: USP25 regulates Wnt signaling by controlling the stability of tankyrases.

PubMed ID: 28619731

DOI: 10.1101/gad.300889.117

PubMed ID: 30478318

Title: A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25.

PubMed ID: 30478318

DOI: 10.1038/s41467-018-07510-5

PubMed ID: 30926243

Title: Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities.

PubMed ID: 30926243

DOI: 10.1016/j.molcel.2019.02.029

Sequence Information:

  • Length: 1055
  • Mass: 122218
  • Checksum: 0B9CECDCAD619CF2
  • Sequence:
    • MTVEQNVLQQ SAAQKHQQTF LNQLREITGI NDTQILQQAL KDSNGNLELA VAFLTAKNAK 
TPQQEETTYY QTALPGNDRY ISVGSQADTN VIDLTGDDKD DLQRAIALSL AESNRAFRET 
GITDEEQAIS RVLEASIAEN KACLKRTPTE VWRDSRNPYD RKRQDKAPVG LKNVGNTCWF 
SAVIQSLFNL LEFRRLVLNY KPPSNAQDLP RNQKEHRNLP FMRELRYLFA LLVGTKRKYV 
DPSRAVEILK DAFKSNDSQQ QDVSEFTHKL LDWLEDAFQM KAEEETDEEK PKNPMVELFY 
GRFLAVGVLE GKKFENTEMF GQYPLQVNGF KDLHECLEAA MIEGEIESLH SENSGKSGQE 
HWFTELPPVL TFELSRFEFN QALGRPEKIH NKLEFPQVLY LDRYMHRNRE ITRIKREEIK 
RLKDYLTVLQ QRLERYLSYG SGPKRFPLVD VLQYALEFAS SKPVCTSPVD DIDASSPPSG 
SIPSQTLPST TEQQGALSSE LPSTSPSSVA AISSRSVIHK PFTQSRIPPD LPMHPAPRHI 
TEEELSVLES CLHRWRTEIE NDTRDLQESI SRIHRTIELM YSDKSMIQVP YRLHAVLVHE 
GQANAGHYWA YIFDHRESRW MKYNDIAVTK SSWEELVRDS FGGYRNASAY CLMYINDKAQ 
FLIQEEFNKE TGQPLVGIET LPPDLRDFVE EDNQRFEKEL EEWDAQLAQK ALQEKLLASQ 
KLRESETSVT TAQAAGDPEY LEQPSRSDFS KHLKEETIQI ITKASHEHED KSPETVLQSA 
IKLEYARLVK LAQEDTPPET DYRLHHVVVY FIQNQAPKKI IEKTLLEQFG DRNLSFDERC 
HNIMKVAQAK LEMIKPEEVN LEEYEEWHQD YRKFRETTMY LIIGLENFQR ESYIDSLLFL 
ICAYQNNKEL LSKGLYRGHD EELISHYRRE CLLKLNEQAA ELFESGEDRE VNNGLIIMNE 
FIVPFLPLLL VDEMEEKDIL AVEDMRNRWC SYLGQEMEPH LQEKLTDFLP KLLDCSMEIK 
SFHEPPKLPS YSTHELCERF ARIMLSLSRT PADGR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.