Details for: CPSF1

Gene ID: 29894

Symbol: CPSF1

Ensembl ID: ENSG00000071894

Description: cleavage and polyadenylation specific factor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 93.1883
    Cell Significance Index: -14.5000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 58.6256
    Cell Significance Index: -14.8700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 40.4768
    Cell Significance Index: -19.1100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 28.4640
    Cell Significance Index: -19.1000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.4717
    Cell Significance Index: -16.6100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.6185
    Cell Significance Index: -17.7300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.3360
    Cell Significance Index: -17.1100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.9197
    Cell Significance Index: -6.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.9674
    Cell Significance Index: 319.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.5962
    Cell Significance Index: 45.9900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2577
    Cell Significance Index: 136.8000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.2386
    Cell Significance Index: 74.3600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7027
    Cell Significance Index: 31.8500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6587
    Cell Significance Index: 45.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5770
    Cell Significance Index: 114.5000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5391
    Cell Significance Index: 11.6800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4151
    Cell Significance Index: 83.2700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4029
    Cell Significance Index: 11.2600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3705
    Cell Significance Index: 334.5000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2993
    Cell Significance Index: 15.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2857
    Cell Significance Index: 33.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2684
    Cell Significance Index: 6.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2675
    Cell Significance Index: 17.2600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2662
    Cell Significance Index: 12.4100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2212
    Cell Significance Index: 4.7100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.1989
    Cell Significance Index: 2.7900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1756
    Cell Significance Index: 33.4100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1755
    Cell Significance Index: 62.9500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1721
    Cell Significance Index: 93.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1454
    Cell Significance Index: 26.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1429
    Cell Significance Index: 24.4000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1349
    Cell Significance Index: 13.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1315
    Cell Significance Index: 90.9300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1199
    Cell Significance Index: 2.5100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1188
    Cell Significance Index: 16.3200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.1156
    Cell Significance Index: 1.4800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1074
    Cell Significance Index: 47.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0972
    Cell Significance Index: 11.9600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0911
    Cell Significance Index: 4.6000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0764
    Cell Significance Index: 2.0100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0717
    Cell Significance Index: 1.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0644
    Cell Significance Index: 4.0600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0620
    Cell Significance Index: 2.1800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0295
    Cell Significance Index: 3.8200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0230
    Cell Significance Index: 2.9500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0175
    Cell Significance Index: 0.4000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0119
    Cell Significance Index: 0.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0090
    Cell Significance Index: 0.4200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0047
    Cell Significance Index: 0.3300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0021
    Cell Significance Index: 3.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0024
    Cell Significance Index: -4.4900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0031
    Cell Significance Index: -4.8100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0072
    Cell Significance Index: -0.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0073
    Cell Significance Index: -9.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0094
    Cell Significance Index: -7.0800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0144
    Cell Significance Index: -0.5000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0168
    Cell Significance Index: -10.6500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0172
    Cell Significance Index: -12.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0197
    Cell Significance Index: -14.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0263
    Cell Significance Index: -14.8600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0264
    Cell Significance Index: -11.9900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0399
    Cell Significance Index: -3.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0422
    Cell Significance Index: -4.3100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0558
    Cell Significance Index: -3.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0610
    Cell Significance Index: -6.9900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0618
    Cell Significance Index: -1.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0661
    Cell Significance Index: -1.8000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0726
    Cell Significance Index: -10.5500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0750
    Cell Significance Index: -5.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0766
    Cell Significance Index: -3.3900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0878
    Cell Significance Index: -18.4900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1022
    Cell Significance Index: -2.6100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1027
    Cell Significance Index: -11.9700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1394
    Cell Significance Index: -5.2800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1423
    Cell Significance Index: -7.4700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1551
    Cell Significance Index: -9.5100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1587
    Cell Significance Index: -16.5200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1632
    Cell Significance Index: -2.4600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1845
    Cell Significance Index: -2.0100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1859
    Cell Significance Index: -1.5800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.2014
    Cell Significance Index: -2.1900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2081
    Cell Significance Index: -16.4800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2235
    Cell Significance Index: -3.8300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2244
    Cell Significance Index: -6.5900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2339
    Cell Significance Index: -6.8900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2611
    Cell Significance Index: -7.4900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2800
    Cell Significance Index: -3.8200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2873
    Cell Significance Index: -11.7700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2943
    Cell Significance Index: -4.2200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3089
    Cell Significance Index: -10.8200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3182
    Cell Significance Index: -8.1800
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.3275
    Cell Significance Index: -4.4200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3339
    Cell Significance Index: -10.6400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3565
    Cell Significance Index: -4.2500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3574
    Cell Significance Index: -11.7000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3828
    Cell Significance Index: -7.9900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3871
    Cell Significance Index: -14.2100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3924
    Cell Significance Index: -6.7900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3979
    Cell Significance Index: -7.3600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3985
    Cell Significance Index: -8.6100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CPSF1 is a highly conserved protein, with high sequence identity across species, indicating its essential role in RNA 3'-end processing. The protein consists of two subunits, CPSF1A and CPSF1B, which interact with other factors to regulate pre-mRNA processing. CPSF1 is specifically localized to the nucleus, where it interacts with RNA polymerase II and other factors involved in transcriptional regulation. The protein is also highly expressed in various tissues, including the nasal mucosa, intestinal crypt stem cells, and extravillous trophoblasts. **Pathways and Functions:** CPSF1 is integral to the co-transcriptional RNA 3'-end processing pathway, which involves the cleavage and polyadenylation of pre-mRNAs. The protein interacts with other factors, such as cleavage and polyadenylation specificity factor subunit 2 (CPSF2), to regulate the cleavage and polyadenylation of pre-mRNAs. This process is crucial for the proper translation of genes, as it ensures the removal of introns and the addition of a poly(A) tail, which facilitates mRNA stability and translation. In addition to its role in RNA 3'-end processing, CPSF1 is also involved in other cellular processes, including gene expression, transcription, and metabolism of RNA. The protein interacts with RNA polymerase II and other transcriptional regulators to modulate gene expression, and it is also involved in the regulation of RNA metabolism, including the processing of tRNAs and RNAs. **Clinical Significance:** Dysregulation of CPSF1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. For example, aberrant expression of CPSF1 has been observed in certain types of cancer, including breast cancer and colon cancer, where it is associated with poor prognosis. Additionally, CPSF1 has been implicated in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, where it is thought to play a role in the regulation of gene expression and RNA metabolism. In conclusion, CPSF1 is a critical component of the co-transcriptional RNA 3'-end processing machinery, playing a pivotal role in the maturation of messenger RNAs in eukaryotic cells. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the mechanisms of RNA 3'-end processing and the regulation of gene expression. Further research is needed to fully elucidate the role of CPSF1 in disease and to develop therapeutic strategies targeting this protein. **Significant Expressions of CPSF1:** CPSF1 is highly expressed in the following cells: - Nasal mucosa goblet cell - Absorptive cell - Intestinal crypt stem cell of colon - Tuft cell of colon - BEST4+ intestinal epithelial cell - Human - Transit amplifying cell - Abnormal cell - Extravillous trophoblast - Proerythroblast - Neoplastic cell **Protein:** CPSF1_HUMAN (Cleavage and polyadenylation specificity factor subunit 1) **Pathways/Ontology:** - Co-transcriptional RNA 3'-end processing - Cleavage and polyadenylation pathway - Enzyme binding - Gene expression (transcription) - Metabolism of RNA - mRNA 3'-end processing - mRNA 3'-utr au-rich region binding - mRNA cleavage and polyadenylation specificity factor complex - mRNA polyadenylation - Nucleoplasm - Nucleus - Processing of capped intron-containing pre-mrna - Processing of capped intronless pre-mrna - Processing of intronless pre-mrnas - Protein binding - RNA polymerase II transcription - RNA polymerase II transcription termination - Transport of mature mRNA derived from an intronless transcript - Transport of mature mRNAs derived from intronless transcripts - Transport of mature transcript to cytoplasm - tRNA processing - tRNA processing in the nucleus

Genular Protein ID: 790866729

Symbol: CPSF1_HUMAN

Name: Cleavage and polyadenylation specificity factor subunit 1

UniProtKB Accession Codes:

Q10570 Q96AF0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 2 EMDB 8 Ensembl 4 ExpressionAtlas 1 GO 7 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7590244

Title: The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation.

PubMed ID: 7590244

DOI: 10.1101/gad.9.21.2672

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11739730

Title: SRm160 splicing coactivator promotes transcript 3'-end cleavage.

PubMed ID: 11739730

DOI: 10.1128/mcb.22.1.148-160.2002

PubMed ID: 14749727

Title: Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.

PubMed ID: 14749727

DOI: 10.1038/sj.emboj.7600070

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21102410

Title: The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.

PubMed ID: 21102410

DOI: 10.1038/emboj.2010.287

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30689892

Title: CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection.

PubMed ID: 30689892

DOI: 10.1093/hmg/ddz029

Sequence Information:

  • Length: 1443
  • Mass: 160884
  • Checksum: 7E1DF4D8A93487A4
  • Sequence:
    • MYAVYKQAHP PTGLEFSMYC NFFNNSERNL VVAGTSQLYV YRLNRDAEAL TKNDRSTEGK 
AHREKLELAA SFSFFGNVMS MASVQLAGAK RDALLLSFKD AKLSVVEYDP GTHDLKTLSL 
HYFEEPELRD GFVQNVHTPR VRVDPDGRCA AMLVYGTRLV VLPFRRESLA EEHEGLVGEG 
QRSSFLPSYI IDVRALDEKL LNIIDLQFLH GYYEPTLLIL FEPNQTWPGR VAVRQDTCSI 
VAISLNITQK VHPVIWSLTS LPFDCTQALA VPKPIGGVVV FAVNSLLYLN QSVPPYGVAL 
NSLTTGTTAF PLRTQEGVRI TLDCAQATFI SYDKMVISLK GGEIYVLTLI TDGMRSVRAF 
HFDKAAASVL TTSMVTMEPG YLFLGSRLGN SLLLKYTEKL QEPPASAVRE AADKEEPPSK 
KKRVDATAGW SAAGKSVPQD EVDEIEVYGS EAQSGTQLAT YSFEVCDSIL NIGPCANAAV 
GEPAFLSEEF QNSPEPDLEI VVCSGHGKNG ALSVLQKSIR PQVVTTFELP GCYDMWTVIA 
PVRKEEEDNP KGEGTEQEPS TTPEADDDGR RHGFLILSRE DSTMILQTGQ EIMELDTSGF 
ATQGPTVFAG NIGDNRYIVQ VSPLGIRLLE GVNQLHFIPV DLGAPIVQCA VADPYVVIMS 
AEGHVTMFLL KSDSYGGRHH RLALHKPPLH HQSKVITLCL YRDLSGMFTT ESRLGGARDE 
LGGRSGPEAE GLGSETSPTV DDEEEMLYGD SGSLFSPSKE EARRSSQPPA DRDPAPFRAE 
PTHWCLLVRE NGTMEIYQLP DWRLVFLVKN FPVGQRVLVD SSFGQPTTQG EARREEATRQ 
GELPLVKEVL LVALGSRQSR PYLLVHVDQE LLIYEAFPHD SQLGQGNLKV RFKKVPHNIN 
FREKKPKPSK KKAEGGGAEE GAGARGRVAR FRYFEDIYGY SGVFICGPSP HWLLVTGRGA 
LRLHPMAIDG PVDSFAPFHN VNCPRGFLYF NRQGELRISV LPAYLSYDAP WPVRKIPLRC 
TAHYVAYHVE SKVYAVATST NTPCARIPRM TGEEKEFETI ERDERYIHPQ QEAFSIQLIS 
PVSWEAIPNA RIELQEWEHV TCMKTVSLRS EETVSGLKGY VAAGTCLMQG EEVTCRGRIL 
IMDVIEVVPE PGQPLTKNKF KVLYEKEQKG PVTALCHCNG HLVSAIGQKI FLWSLRASEL 
TGMAFIDTQL YIHQMISVKN FILAADVMKS ISLLRYQEES KTLSLVSRDA KPLEVYSVDF 
MVDNAQLGFL VSDRDRNLMV YMYLPEAKES FGGMRLLRRA DFHVGAHVNT FWRTPCRGAT 
EGLSKKSVVW ENKHITWFAT LDGGIGLLLP MQEKTYRRLL MLQNALTTML PHHAGLNPRA 
FRMLHVDRRT LQNAVRNVLD GELLNRYLYL STMERSELAK KIGTTPDIIL DDLLETDRVT 
AHF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.