Details for: HOOK2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 3.88
Marker Score: 86,743 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 2.89
Marker Score: 1,056 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.4
Marker Score: 6,003 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 2.25
Marker Score: 1,111 - Cell Name: fat cell (CL0000136)
Fold Change: 2.22
Marker Score: 1,239 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.17
Marker Score: 2,455 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.11
Marker Score: 1,468 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 2.06
Marker Score: 1,825 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.96
Marker Score: 2,369 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.96
Marker Score: 820 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.9
Marker Score: 595 - Cell Name: enterocyte (CL0000584)
Fold Change: 1.88
Marker Score: 9,046 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.87
Marker Score: 2,262 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.85
Marker Score: 1,747 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.83
Marker Score: 2,690 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.78
Marker Score: 6,321 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 1.77
Marker Score: 2,720 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.74
Marker Score: 15,021 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.72
Marker Score: 3,040 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.71
Marker Score: 7,158 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.7
Marker Score: 548 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.69
Marker Score: 536 - Cell Name: basal cell (CL0000646)
Fold Change: 1.69
Marker Score: 2,178 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.68
Marker Score: 3,420 - Cell Name: secretory cell (CL0000151)
Fold Change: 1.66
Marker Score: 3,039 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.64
Marker Score: 16,970 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.63
Marker Score: 1,805 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.62
Marker Score: 949 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.61
Marker Score: 12,008 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.61
Marker Score: 6,192 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.61
Marker Score: 55,624 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.6
Marker Score: 2,625 - Cell Name: pneumocyte (CL0000322)
Fold Change: 1.6
Marker Score: 2,565 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.59
Marker Score: 1,676 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.59
Marker Score: 770 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 1.57
Marker Score: 4,931 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.55
Marker Score: 856 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.55
Marker Score: 454 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.53
Marker Score: 1,322 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.53
Marker Score: 56,429 - Cell Name: club cell (CL0000158)
Fold Change: 1.53
Marker Score: 1,785 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.52
Marker Score: 416 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.52
Marker Score: 14,304 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.52
Marker Score: 5,960 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.51
Marker Score: 3,559 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.48
Marker Score: 551 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.48
Marker Score: 1,986 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.45
Marker Score: 89,298 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.45
Marker Score: 5,356 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.44
Marker Score: 2,220 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.43
Marker Score: 1,484 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.43
Marker Score: 3,255 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.42
Marker Score: 411 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.42
Marker Score: 22,814 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.42
Marker Score: 662 - Cell Name: neuron (CL0000540)
Fold Change: 1.42
Marker Score: 5,770 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.41
Marker Score: 12,151 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.37
Marker Score: 1,370 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 1.37
Marker Score: 1,225 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.35
Marker Score: 2,752 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.35
Marker Score: 787 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.35
Marker Score: 12,807 - Cell Name: stem cell (CL0000034)
Fold Change: 1.34
Marker Score: 3,183 - Cell Name: peptic cell (CL0000155)
Fold Change: 1.32
Marker Score: 554 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.32
Marker Score: 3,231 - Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
Fold Change: 1.32
Marker Score: 318 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 1.32
Marker Score: 10,270 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 1.31
Marker Score: 8,541 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.31
Marker Score: 1,329 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.3
Marker Score: 1,403 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.3
Marker Score: 5,383 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.29
Marker Score: 49,056 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.27
Marker Score: 19,938 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.26
Marker Score: 659 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 1.26
Marker Score: 332 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.25
Marker Score: 753 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.24
Marker Score: 290 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.23
Marker Score: 4,773 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.23
Marker Score: 305 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 1.23
Marker Score: 461 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.2
Marker Score: 804 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 1.2
Marker Score: 6,327 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.2
Marker Score: 23,794 - Cell Name: tracheobronchial goblet cell (CL0019003)
Fold Change: 1.18
Marker Score: 324 - Cell Name: paneth cell (CL0000510)
Fold Change: 1.18
Marker Score: 820 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 1.17
Marker Score: 230 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.16
Marker Score: 7,389 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 1.16
Marker Score: 366 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.14
Marker Score: 2,594 - Cell Name: keratinocyte (CL0000312)
Fold Change: 1.13
Marker Score: 943 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.13
Marker Score: 888 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.13
Marker Score: 656 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.11
Marker Score: 23,738 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.1
Marker Score: 8,466 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.1
Marker Score: 775 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.09
Marker Score: 16,295 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.07
Marker Score: 216 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.06
Marker Score: 546 - Cell Name: precursor cell (CL0011115)
Fold Change: 1.05
Marker Score: 256 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.05
Marker Score: 690
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3563277733
Symbol: HOOK2_HUMAN
Name: Protein Hook homolog 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9927460
Title: Genetic analysis of hook, a gene required for endocytic trafficking in Drosophila.
PubMed ID: 9927460
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11238449
Title: The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.
PubMed ID: 11238449
PubMed ID: 17540036
PubMed ID: 17140400
Title: Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function.
PubMed ID: 17140400
PubMed ID: 18799622
Title: An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.
PubMed ID: 18799622
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19273536
Title: SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans.
PubMed ID: 19273536
DOI: 10.1093/hmg/ddp099
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 32073997
Title: The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.
PubMed ID: 32073997
Sequence Information:
- Length: 719
- Mass: 83207
- Checksum: FDF5F8A53DEE9DB6
- Sequence:
MSVDKAELCG SLLTWLQTFH VPSPCASPQD LSSGLAVAYV LNQIDPSWFN EAWLQGISED PGPNWKLKVS NLKMVLRSLV EYSQDVLAHP VSEEHLPDVS LIGEFSDPAE LGKLLQLVLG CAISCEKKQD HIQRIMTLEE SVQHVVMEAI QELMTKDTPD SLSPETYGNF DSQSRRYYFL SEEAEEGDEL QQRCLDLERQ LMLLSEEKQS LAQENAGLRE RMGRPEGEGT PGLTAKKLLL LQSQLEQLQE ENFRLESGRE DERLRCAELE REVAELQHRN QALTSLAQEA QALKDEMDEL RQSSERAGQL EATLTSCRRR LGELRELRRQ VRQLEERNAG HAERTRQLED ELRRAGSLRA QLEAQRRQVQ ELQGQRQEEA MKAEKWLFEC RNLEEKYESV TKEKERLLAE RDSLREANEE LRCAQLQPRG LTQADPSLDP TSTPVDNLAA EILPAELRET LLRLQLENKR LCRQEAADRE RQEELQRHLE DANRARHGLE TQHRLNQQQL SELRAQVEDL QKALQEQGGK TEDAISILLK RKLEEHLQKL HEADLELQRK REYIEELEPP TDSSTARRIE ELQHNLQKKD ADLRAMEERY RRYVDKARMV MQTMEPKQRP AAGAPPELHS LRTQLRERDV RIRHLEMDFE KSRSQREQEE KLLISAWYNM GMALQQRAGE ERAPAHAQSF LAQQRLATNS RRGPLGRLAS LNLRPTDKH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.