Details for: SEC61A1

Gene ID: 29927

Symbol: SEC61A1

Ensembl ID: ENSG00000058262

Description: SEC61 translocon subunit alpha 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 245.1699
    Cell Significance Index: -38.1400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 154.0746
    Cell Significance Index: -39.0800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 95.9708
    Cell Significance Index: -45.3100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 94.0537
    Cell Significance Index: -38.2100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 86.8415
    Cell Significance Index: -44.6700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 67.4940
    Cell Significance Index: -45.2900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 40.0736
    Cell Significance Index: -38.2600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.4602
    Cell Significance Index: -41.2600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.3013
    Cell Significance Index: -40.9900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.6588
    Cell Significance Index: -42.0600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.2004
    Cell Significance Index: -31.3300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.3074
    Cell Significance Index: -20.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.3080
    Cell Significance Index: 107.6100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.9723
    Cell Significance Index: 214.5300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.4419
    Cell Significance Index: 38.5000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.3160
    Cell Significance Index: 224.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9621
    Cell Significance Index: 190.9400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9515
    Cell Significance Index: 154.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.9379
    Cell Significance Index: 25.5300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8354
    Cell Significance Index: 22.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.8351
    Cell Significance Index: 456.0700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7668
    Cell Significance Index: 138.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7400
    Cell Significance Index: 34.7800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.7225
    Cell Significance Index: 20.7100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.7085
    Cell Significance Index: 14.8300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6785
    Cell Significance Index: 19.5500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6620
    Cell Significance Index: 45.7800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6310
    Cell Significance Index: 47.0300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6177
    Cell Significance Index: 14.2700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.6157
    Cell Significance Index: 79.5400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6036
    Cell Significance Index: 82.8900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.5841
    Cell Significance Index: 15.6300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5311
    Cell Significance Index: 27.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5281
    Cell Significance Index: 100.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5067
    Cell Significance Index: 14.1600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4958
    Cell Significance Index: 49.0500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4909
    Cell Significance Index: 60.3600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4869
    Cell Significance Index: 97.6800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4546
    Cell Significance Index: 20.6100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3890
    Cell Significance Index: 172.0000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3130
    Cell Significance Index: 40.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2973
    Cell Significance Index: 8.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2892
    Cell Significance Index: 261.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2684
    Cell Significance Index: 96.2800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1919
    Cell Significance Index: 6.6700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1616
    Cell Significance Index: 19.0600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1487
    Cell Significance Index: 102.8500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1333
    Cell Significance Index: 10.2300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0976
    Cell Significance Index: 73.9100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0883
    Cell Significance Index: 1.8800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0288
    Cell Significance Index: 2.0400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0140
    Cell Significance Index: 0.9000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0096
    Cell Significance Index: 0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0084
    Cell Significance Index: 15.7500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0047
    Cell Significance Index: -7.2800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0078
    Cell Significance Index: -14.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0082
    Cell Significance Index: -11.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0116
    Cell Significance Index: -7.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0165
    Cell Significance Index: -12.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0197
    Cell Significance Index: -14.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0344
    Cell Significance Index: -3.5100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0380
    Cell Significance Index: -23.7000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0430
    Cell Significance Index: -1.1300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0452
    Cell Significance Index: -20.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0482
    Cell Significance Index: -27.1600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0879
    Cell Significance Index: -18.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1121
    Cell Significance Index: -32.2500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1135
    Cell Significance Index: -13.0100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1187
    Cell Significance Index: -2.0000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1241
    Cell Significance Index: -0.7500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1996
    Cell Significance Index: -29.0100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2020
    Cell Significance Index: -1.8600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2264
    Cell Significance Index: -5.6600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2514
    Cell Significance Index: -29.3000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2616
    Cell Significance Index: -8.3800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2814
    Cell Significance Index: -15.7900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2926
    Cell Significance Index: -5.4100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3008
    Cell Significance Index: -7.3400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3033
    Cell Significance Index: -18.6400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3395
    Cell Significance Index: -38.7500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3453
    Cell Significance Index: -23.2200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3900
    Cell Significance Index: -40.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3951
    Cell Significance Index: -24.9000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4075
    Cell Significance Index: -24.4700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4323
    Cell Significance Index: -6.3800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4736
    Cell Significance Index: -5.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4867
    Cell Significance Index: -6.6400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5047
    Cell Significance Index: -39.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5166
    Cell Significance Index: -31.6700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5167
    Cell Significance Index: -27.1300
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.5682
    Cell Significance Index: -5.8800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5815
    Cell Significance Index: -11.3500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6160
    Cell Significance Index: -32.0900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6459
    Cell Significance Index: -16.5000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7147
    Cell Significance Index: -18.3700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7366
    Cell Significance Index: -32.5800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.7609
    Cell Significance Index: -9.7500
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -0.7701
    Cell Significance Index: -16.0600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.8680
    Cell Significance Index: -8.9900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.8709
    Cell Significance Index: -32.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Subunit of the SEC61 translocon**: SEC61A1 is a subunit of the SEC61 translocon complex, which is responsible for the translocation of proteins across the ER membrane. 2. **Cotranslational targeting**: The SEC61 translocon complex, including SEC61A1, facilitates the cotranslational targeting of proteins to the ER membrane. 3. **Protein insertion into ER membrane**: SEC61A1 is involved in the insertion of newly synthesized proteins into the ER lumen. 4. **High expression in immune cells**: The SEC61A1 gene is highly expressed in immune cells, such as plasmablasts, IgA-producing cells, and decidual cells, indicating its critical role in the adaptive immune response. **Pathways and Functions** 1. **Adaptive immune system**: SEC61A1 plays a crucial role in the adaptive immune response, particularly in the processing and presentation of antigens to T-cells. 2. **Antigen processing-cross presentation**: The SEC61 translocon complex, including SEC61A1, is involved in the cross-presentation of antigens from dying cells to antigen-presenting cells (APCs). 3. **Calcium channel activity**: SEC61A1 has been implicated in the regulation of calcium channel activity, which is essential for various cellular processes, including immune responses. 4. **Protein binding and translocation**: SEC61A1 interacts with other proteins to facilitate the binding and translocation of proteins across the ER membrane. **Clinical Significance** 1. **Autoimmune diseases**: Abnormalities in the SEC61A1 gene have been linked to autoimmune diseases, such as rheumatoid arthritis and lupus, highlighting its potential role in immune dysregulation. 2. **Cancer**: The SEC61 translocon complex, including SEC61A1, has been implicated in the development and progression of various cancers, including breast, lung, and colon cancer. 3. **Infectious diseases**: SEC61A1 has been shown to play a role in the immune response to infections, such as tuberculosis and malaria. 4. **Immunodeficiency disorders**: Mutations in the SEC61A1 gene have been associated with immunodeficiency disorders, such as severe combined immunodeficiency (SCID). In conclusion, the SEC61A1 gene plays a critical role in the adaptive immune response, antigen processing, and presentation, and has implications in various diseases, including autoimmune disorders, cancer, and infectious diseases. Further research is necessary to fully elucidate the functions and clinical significance of the SEC61A1 gene.

Genular Protein ID: 4060938873

Symbol: S61A1_HUMAN

Name: Protein transport protein Sec61 subunit alpha isoform 1

UniProtKB Accession Codes:

P61619 P38378 P57726 Q5JPF8 Q8N0Z4 Q8N3U3 Q8NC71 Q9BU16 Q9Y2R3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EMDB 20 Ensembl 2 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 8616892

Title: The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process.

PubMed ID: 8616892

DOI: 10.1016/s0092-8674(00)81115-0

PubMed ID: 12475939

Title: Different transmembrane domains associate with distinct endoplasmic reticulum components during membrane integration of a polytopic protein.

PubMed ID: 12475939

DOI: 10.1091/mbc.e02-04-0198

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22375059

Title: Different effects of Sec61alpha, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.

PubMed ID: 22375059

DOI: 10.1242/jcs.096727

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29719251

Title: Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier.

PubMed ID: 29719251

DOI: 10.1016/j.celrep.2018.03.122

PubMed ID: 32814900

Title: An intramembrane chaperone complex facilitates membrane protein biogenesis.

PubMed ID: 32814900

DOI: 10.1038/s41586-020-2624-y

PubMed ID: 32820719

Title: An ER translocon for multi-pass membrane protein biogenesis.

PubMed ID: 32820719

DOI: 10.7554/elife.56889

PubMed ID: 36261522

Title: Substrate-driven assembly of a translocon for multipass membrane proteins.

PubMed ID: 36261522

DOI: 10.1038/s41586-022-05330-8

PubMed ID: 27392076

Title: Heterozygous loss-of-function SEC61A1 mutations cause autosomal-dominant tubulo-interstitial and glomerulocystic kidney disease with anemia.

PubMed ID: 27392076

DOI: 10.1016/j.ajhg.2016.05.028

PubMed ID: 28782633

Title: Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1).

PubMed ID: 28782633

DOI: 10.1016/j.jaci.2017.06.042

PubMed ID: 32325141

Title: Defective Sec61alpha1 underlies a novel cause of autosomal dominant severe congenital neutropenia.

PubMed ID: 32325141

DOI: 10.1016/j.jaci.2020.03.034

PubMed ID: 33185949

Title: De novo SEC61A1 mutation in autosomal dominant tubulo-interstitial kidney disease: Phenotype expansion and review of literature.

PubMed ID: 33185949

DOI: 10.1111/jpc.15148

Sequence Information:

  • Length: 476
  • Mass: 52265
  • Checksum: 44A9B7B37C7C82E4
  • Sequence:
    • MAIKFLEVIK PFCVILPEIQ KPERKIQFKE KVLWTAITLF IFLVCCQIPL FGIMSSDSAD 
PFYWMRVILA SNRGTLMELG ISPIVTSGLI MQLLAGAKII EVGDTPKDRA LFNGAQKLFG 
MIITIGQSIV YVMTGMYGDP SEMGAGICLL ITIQLFVAGL IVLLLDELLQ KGYGLGSGIS 
LFIATNICET IVWKAFSPTT VNTGRGMEFE GAIIALFHLL ATRTDKVRAL REAFYRQNLP 
NLMNLIATIF VFAVVIYFQG FRVDLPIKSA RYRGQYNTYP IKLFYTSNIP IILQSALVSN 
LYVISQMLSA RFSGNLLVSL LGTWSDTSSG GPARAYPVGG LCYYLSPPES FGSVLEDPVH 
AVVYIVFMLG SCAFFSKTWI EVSGSSAKDV AKQLKEQQMV MRGHRETSMV HELNRYIPTA 
AAFGGLCIGA LSVLADFLGA IGSGTGILLA VTIIYQYFEI FVKEQSEVGS MGALLF

Genular Protein ID: 648958828

Symbol: B3KME8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KME8

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 3 GO 6 Gene3D 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 170
  • Mass: 18176
  • Checksum: A9592F3C68619F26
  • Sequence:
    • MLSARFSGNL LVSLLGTWSD TSSGGPARAY PVGGLCYYLS PPESFGSVLE DPVHAVVYIV 
FMLGSCAFFS KTWIEVSGSS AKDVAKQLKE QQMVMRGHRE TSMVHELNRY IPTAAAFGGL 
CIGALSVLAD FLGAIGSGTG ILLAVTIIYQ YFEIFVKEQS EVGSMGALLF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.