Details for: NOP53

Gene ID: 29997

Symbol: NOP53

Ensembl ID: ENSG00000105373

Description: NOP53 ribosome biogenesis factor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 279.6472
    Cell Significance Index: -115.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 262.2969
    Cell Significance Index: -106.5600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 246.2708
    Cell Significance Index: -116.2700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 227.7670
    Cell Significance Index: -117.1600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 174.2118
    Cell Significance Index: -116.9000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 112.8576
    Cell Significance Index: -107.7500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 26.0430
    Cell Significance Index: -79.9900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.3544
    Cell Significance Index: -46.4900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 8.4108
    Cell Significance Index: 148.6300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 6.1930
    Cell Significance Index: 800.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 5.4545
    Cell Significance Index: 351.9000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 5.2869
    Cell Significance Index: 246.5000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 5.2111
    Cell Significance Index: 59.2000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 4.9181
    Cell Significance Index: 366.5400
  • Cell Name: theca cell (CL0000503)
    Fold Change: 4.5498
    Cell Significance Index: 26.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 4.4543
    Cell Significance Index: 315.0300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 3.9287
    Cell Significance Index: 42.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.9170
    Cell Significance Index: 537.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.7628
    Cell Significance Index: 462.6800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 3.7291
    Cell Significance Index: 1648.7400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.6911
    Cell Significance Index: 100.4700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 3.6624
    Cell Significance Index: 76.6600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.6484
    Cell Significance Index: 104.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.6017
    Cell Significance Index: 169.2800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 3.5648
    Cell Significance Index: 82.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.4544
    Cell Significance Index: 622.7300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.8159
    Cell Significance Index: 74.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 2.7047
    Cell Significance Index: 2442.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.5586
    Cell Significance Index: 88.9100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.1886
    Cell Significance Index: 280.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0592
    Cell Significance Index: 59.3300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.0181
    Cell Significance Index: 1102.1500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.9639
    Cell Significance Index: 15.6800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.8361
    Cell Significance Index: 95.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.7683
    Cell Significance Index: 174.9200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.6467
    Cell Significance Index: 98.8600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.5184
    Cell Significance Index: 179.0600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.0971
    Cell Significance Index: 32.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9558
    Cell Significance Index: 49.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8257
    Cell Significance Index: 37.4300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.5987
    Cell Significance Index: 4.3000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4253
    Cell Significance Index: 80.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3449
    Cell Significance Index: 56.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2279
    Cell Significance Index: 157.5900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2227
    Cell Significance Index: 7.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2039
    Cell Significance Index: 34.8200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1963
    Cell Significance Index: 38.9600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1111
    Cell Significance Index: 84.1100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1007
    Cell Significance Index: 1.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0751
    Cell Significance Index: 2.4000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0419
    Cell Significance Index: 2.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0174
    Cell Significance Index: 12.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0031
    Cell Significance Index: -0.1600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0228
    Cell Significance Index: -0.2100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0269
    Cell Significance Index: -0.3500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0349
    Cell Significance Index: -3.5600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0375
    Cell Significance Index: -70.6300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0639
    Cell Significance Index: -1.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0706
    Cell Significance Index: -130.2700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0845
    Cell Significance Index: -130.1200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1016
    Cell Significance Index: -138.1100
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.1120
    Cell Significance Index: -1.9300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1321
    Cell Significance Index: -6.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1371
    Cell Significance Index: -101.5600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.1393
    Cell Significance Index: -49.9800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1537
    Cell Significance Index: -97.6200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1912
    Cell Significance Index: -7.8300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1993
    Cell Significance Index: -112.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2062
    Cell Significance Index: -128.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2330
    Cell Significance Index: -105.7500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.2704
    Cell Significance Index: -54.2400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3661
    Cell Significance Index: -105.3500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4071
    Cell Significance Index: -10.4000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5470
    Cell Significance Index: -62.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.6228
    Cell Significance Index: -131.1700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.6935
    Cell Significance Index: -100.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.7593
    Cell Significance Index: -16.4500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8120
    Cell Significance Index: -94.6300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.8506
    Cell Significance Index: -23.7700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8562
    Cell Significance Index: -67.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.8996
    Cell Significance Index: -62.2200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.9893
    Cell Significance Index: -24.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.0914
    Cell Significance Index: -113.6400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.1687
    Cell Significance Index: -21.6000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.2292
    Cell Significance Index: -75.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.2890
    Cell Significance Index: -72.3300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.4162
    Cell Significance Index: -21.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.5101
    Cell Significance Index: -115.8800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.5342
    Cell Significance Index: -94.0600
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -1.5753
    Cell Significance Index: -8.5900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.6872
    Cell Significance Index: -23.0200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -2.1389
    Cell Significance Index: -36.0300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.3423
    Cell Significance Index: -68.9900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -2.5027
    Cell Significance Index: -110.7000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -2.5720
    Cell Significance Index: -30.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -2.6365
    Cell Significance Index: -67.7700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.6661
    Cell Significance Index: -97.8700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -2.8066
    Cell Significance Index: -58.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -2.9416
    Cell Significance Index: -111.3900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -2.9898
    Cell Significance Index: -30.9500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** NOP53 exhibits a unique set of characteristics that distinguish it from other genes. Its primary function is to regulate ribosome biogenesis, which is essential for protein synthesis. NOP53 also engages in negative regulation of various signaling pathways, including those involved in DNA damage response, apoptosis, and cell cycle regulation. Its expression is tightly linked to the expression of other genes, including those involved in the p53 pathway, highlighting its role as a negative regulator of this pathway. **Pathways and Functions:** NOP53 is involved in several critical pathways that regulate cellular homeostasis and response to stress. These include: 1. **Ribosome biogenesis:** NOP53 is essential for the synthesis of ribosomal subunits, which are necessary for protein synthesis. 2. **DNA damage response:** NOP53 acts as a negative regulator of the DNA damage response pathway, where it inhibits the activity of key enzymes involved in DNA repair. 3. **Apoptosis:** NOP53 is a negative regulator of the apoptotic pathway, where it inhibits the activation of pro-apoptotic proteins. 4. **Cell cycle regulation:** NOP53 regulates the cell cycle by inhibiting the activity of key cyclin-dependent kinases. 5. **Hypoxia response:** NOP53 is a negative regulator of the hypoxia response pathway, where it inhibits the activity of key transcription factors involved in hypoxia adaptation. **Clinical Significance:** NOP53 has significant implications for various diseases, including: 1. **Cancer:** NOP53 is often mutated or deleted in various types of cancer, including breast cancer, colon cancer, and leukemia. The loss of NOP53 function can lead to uncontrolled cell proliferation and tumorigenesis. 2. **Neurodegenerative diseases:** NOP53 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where it may play a role in regulating protein synthesis and apoptosis. 3. **Immune disorders:** NOP53 is expressed in immune cells, where it may play a role in regulating immune responses and preventing autoimmune diseases. 4. **Muscle disorders:** NOP53 is expressed in muscle cells, where it may play a role in regulating muscle growth and development. In conclusion, NOP53 is a critical gene that plays a pivotal role in maintaining cellular homeostasis and response to stress. Its dysregulation has significant implications for various diseases, highlighting the need for further research into the mechanisms by which NOP53 regulates cellular processes.

Genular Protein ID: 3068025049

Symbol: NOP53_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NZM5 Q9BTC6 Q9HAX6 Q9NPP1 Q9NPR4 Q9UFI2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EMDB 15 Ensembl 1 ExpressionAtlas 1 GO 32 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 15 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10708517

Title: A transcript map of the chromosome 19q-Arm glioma tumor suppressor region.

PubMed ID: 10708517

DOI: 10.1006/geno.1999.6101

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10196275

Title: A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and is recruited to the nucleus after infection.

PubMed ID: 10196275

DOI: 10.1128/jvi.73.5.3810-3817.1999

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 15355975

Title: Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein.

PubMed ID: 15355975

DOI: 10.1074/jbc.c400377200

PubMed ID: 16971513

Title: Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation.

PubMed ID: 16971513

DOI: 10.1091/mbc.e06-04-0301

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20042497

Title: GLTSCR2/PICT-1, a putative tumor suppressor gene product, induces the nucleolar targeting of the Kaposi's sarcoma-associated herpesvirus KS-Bcl-2 protein.

PubMed ID: 20042497

DOI: 10.1128/jvi.00757-09

PubMed ID: 21741933

Title: Involvement of GLTSCR2 in the DNA Damage Response.

PubMed ID: 21741933

DOI: 10.1016/j.ajpath.2011.05.041

PubMed ID: 21167305

Title: Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus.

PubMed ID: 21167305

DOI: 10.1016/j.biocel.2010.12.011

PubMed ID: 22522597

Title: Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses.

PubMed ID: 22522597

DOI: 10.1038/cdd.2012.40

PubMed ID: 22292050

Title: Nucleolar localization of GLTSCR2/PICT-1 is mediated by multiple unique nucleolar localization sequences.

PubMed ID: 22292050

DOI: 10.1371/journal.pone.0030825

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24120868

Title: The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress.

PubMed ID: 24120868

DOI: 10.1016/j.celrep.2013.08.049

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24923447

Title: Nucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 protein.

PubMed ID: 24923447

DOI: 10.1074/jbc.m114.571893

PubMed ID: 24735870

Title: The nucleolar PICT-1/GLTSCR2 protein forms homo-oligomers.

PubMed ID: 24735870

DOI: 10.1016/j.jmb.2014.04.006

PubMed ID: 24556985

Title: GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.

PubMed ID: 24556985

DOI: 10.1073/pnas.1400705111

PubMed ID: 25956029

Title: The nucleolar protein GLTSCR2 is an upstream negative regulator of the oncogenic Nucleophosmin-MYC axis.

PubMed ID: 25956029

DOI: 10.1016/j.ajpath.2015.03.016

PubMed ID: 25818168

Title: GLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer.

PubMed ID: 25818168

DOI: 10.1111/jcmm.12474

PubMed ID: 26903295

Title: c-Jun N-terminal kinase regulates the nucleoplasmic translocation and stability of nucleolar GLTSCR2 protein.

PubMed ID: 26903295

DOI: 10.1016/j.bbrc.2016.02.070

PubMed ID: 27729611

Title: PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.

PubMed ID: 27729611

DOI: 10.18632/oncotarget.12288

PubMed ID: 27829214

Title: PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.

PubMed ID: 27829214

DOI: 10.18632/oncotarget.13082

PubMed ID: 27824081

Title: The nucleolar protein GLTSCR2 is required for efficient viral replication.

PubMed ID: 27824081

DOI: 10.1038/srep36226

PubMed ID: 27323397

Title: GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF.

PubMed ID: 27323397

DOI: 10.18632/oncotarget.9957

Sequence Information:

  • Length: 478
  • Mass: 54389
  • Checksum: 7F1BA13D04BFB618
  • Sequence:
    • MAAGGSGVGG KRSSKSDADS GFLGLRPTSV DPALRRRRRG PRNKKRGWRR LAQEPLGLEV 
DQFLEDVRLQ ERTSGGLLSE APNEKLFFVD TGSKEKGLTK KRTKVQKKSL LLKKPLRVDL 
ILENTSKVPA PKDVLAHQVP NAKKLRRKEQ LWEKLAKQGE LPREVRRAQA RLLNPSATRA 
KPGPQDTVER PFYDLWASDN PLDRPLVGQD EFFLEQTKKK GVKRPARLHT KPSQAPAVEV 
APAGASYNPS FEDHQTLLSA AHEVELQRQK EAEKLERQLA LPATEQAATQ ESTFQELCEG 
LLEESDGEGE PGQGEGPEAG DAEVCPTPAR LATTEKKTEQ QRRREKAVHR LRVQQAALRA 
ARLRHQELFR LRGIKAQVAL RLAELARRQR RRQARREAEA DKPRRLGRLK YQAPDIDVQL 
SSELTDSLRT LKPEGNILRD RFKSFQRRNM IEPRERAKFK RKYKVKLVEK RAFREIQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.